Prevalite

Hardening of the Arteries, partial biliary obstruction, Itching + 1 more
Treatment
5 FDA approvals
20 Active Studies for Prevalite

What is Prevalite

CholestyramineThe Generic name of this drug
Treatment SummaryCholestyramine (also known as Colestyramine) is a medication that binds to bile acids in the gut and prevents them from being absorbed into the body. It is an ion exchange resin that is very water-soluble, but not water-soluble. This drug is used to treat high cholesterol and other conditions involving bile acids.
Cholestyramine Lightis the brand name
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Prevalite Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cholestyramine Light
Cholestyramine
1994
47

Approved as Treatment by the FDA

Cholestyramine, commonly known as Cholestyramine Light, is approved by the FDA for 5 uses like Hardening of the Arteries and partial biliary obstruction .
Hardening of the Arteries
Helps manage Atherosclerosis
partial biliary obstruction
Itching
Primary Hypercholesterolemia
Pruritus

Effectiveness

How Prevalite Affects PatientsCholesterol is the main ingredient used to create bile acids in the body. During digestion, bile acids are released into the intestines, where most of them are absorbed and returned to the liver. However, cholestyramine resin binds to bile acids in the intestines, forming an insoluble complex that is then excreted and not absorbed back into the liver, reducing the amount of bile acids in circulation.
How Prevalite works in the bodyCholestyramine works by preventing bile acids from reabsorbing into your system. It is made out of a special type of resin that exchanges its negatively-charged ions for the anionic bile acids present in your gastrointestinal tract. This resin is held together by a functional group made from quaternary ammonium and styrene-divinylbenzene copolymer.

When to interrupt dosage

The proffered dosage of Prevalite is contingent upon the determined state, including Hardening of the arteries, Itch and Primary Hypercholesterolemia. The amount of dosage fluctuates according to the technique of delivery (e.g. Oral or Powder, for suspension) as presented in the table beneath.
Condition
Dosage
Administration
Itching
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
Hardening of the Arteries
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
partial biliary obstruction
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
Primary Hypercholesterolemia
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral

Warnings

Prevalite has one contraindication, and thus should not be blended with the ailments listed in the subsequent table.Prevalite Contraindications
Condition
Risk Level
Notes
complete biliary obstruction
Do Not Combine
There are 20 known major drug interactions with Prevalite.
Common Prevalite Drug Interactions
Drug Name
Risk Level
Description
Mycophenolate mofetil
Major
Cholestyramine may increase the excretion rate of Mycophenolate mofetil which could result in a lower serum level and potentially a reduction in efficacy.
Mycophenolic acid
Major
Cholestyramine may increase the excretion rate of Mycophenolic acid which could result in a lower serum level and potentially a reduction in efficacy.
Raloxifene
Major
Cholestyramine can cause a decrease in the absorption of Raloxifene resulting in a reduced serum concentration and potentially a decrease in efficacy.
(R)-warfarin
Minor
Cholestyramine can cause a decrease in the absorption of (R)-warfarin resulting in a reduced serum concentration and potentially a decrease in efficacy.
(S)-Warfarin
Minor
Cholestyramine can cause a decrease in the absorption of (S)-Warfarin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Prevalite Toxicity & Overdose RiskTaking too much of this drug may result in a blockage in the stomach or intestines.
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Prevalite Novel Uses: Which Conditions Have a Clinical Trial Featuring Prevalite?

68 active clinical trials are being conducted to assess the effectiveness of Prevalite in relieving Itch, partial biliary obstruction and Primary Hypercholesterolemia.
Condition
Clinical Trials
Trial Phases
Primary Hypercholesterolemia
10 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Itching
3 Actively Recruiting
Phase 2, Phase 3, Not Applicable
partial biliary obstruction
0 Actively Recruiting
Hardening of the Arteries
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Phase 1

Prevalite Reviews: What are patients saying about Prevalite?

5Patient Review
12/31/2015
Prevalite for Chronic Diarrhea
After my gallbladder was removed, I had really bad diarrhea that made it hard to do anything. Once I started taking Prevalite, everything got better and I could live normally again.
5Patient Review
1/2/2020
Prevalite for Chronic Diarrhea
This medication is really easy to take and mix with milk. It's helped my diarrhea immensely and has been a complete game-changer for me.
5Patient Review
7/1/2016
Prevalite for Chronic Diarrhea
The cancer treatment is going well, but I can't afford it. My supplement only covered $78 for 30 packs.
4.7Patient Review
1/7/2013
Prevalite for Chronic Diarrhea
I had severe problems with diarrhea for several years after my gallbladder was removed. Several doctors told me there was no solution to the problem; my endocrinologist suggested this, and it changed my life. Before, I was apprehensive about eating in a restaurant or going to someone's home for a meal. It has taken a little experimenting to adjust the dosage and frequency, but I've never taken a medication that has made such a difference. Thanks to my wonderful doctor!
4.7Patient Review
6/8/2012
Prevalite for High Amount of Fats in the Blood
I am currently treating the "dumping syndrome" that can occur after a Gall Bladder removal. This stuff has been working great for me so far. I mix it in orange juice to make the taste and texture more palatable. For the gas, I use charcoal capsules which can be found at health food stores.
View All Reviews
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Patient Q&A Section about prevalite

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are side effects of Prevalite?

"If you experience any of the following side effects, speak to your doctor or pharmacist: constipation, stomach/abdominal pain, gas, nausea, or vomiting. Prevention methods for constipation include increasing your intake of dietary fiber, drinking enough water, and exercising."

Answered by AI

What is Prevalite used to treat?

"The drug cholestyramine is available in both a generic form and a brand-name form (Prevalite). It comes as a powder that is mixed with a non-carbonated drink or applesauce and taken orally. Cholestyramine is used to treat high cholesterol (hyperlipidemia) and itching caused by partial bile obstruction."

Answered by AI

Is cholestyramine used to treat diarrhea?

"Cholestyramine powder is most commonly given at a dosage of 4 g per day. The dosage may be increased if needed, but clinical practice suggests that it is often just as effective to give the powder less often, at a dosage of 4 g twice per day."

Answered by AI

What are the side effects of taking cholestyramine?

"Some common gastrointestinal issues include constipation, bloating, stomach pain, gas, and upset stomach. More serious issues can include vomiting, diarrhea, and loss of appetite."

Answered by AI

Clinical Trials for Prevalite

Have you considered Prevalite clinical trials? We made a collection of clinical trials featuring Prevalite, we think they might fit your search criteria.
Have you considered Prevalite clinical trials? We made a collection of clinical trials featuring Prevalite, we think they might fit your search criteria.
Have you considered Prevalite clinical trials? We made a collection of clinical trials featuring Prevalite, we think they might fit your search criteria.
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