Aceon

Congestive heart failure, Hypesthesia, Hypesthesia + 9 more

Treatment

8 FDA approvals

20 Active Studies for Aceon

Treatment for

Congestive heart failure

What is Aceon

PerindoprilThe Generic name of this drug

Treatment SummaryPerindopril is a medication used to lower blood pressure and reduce cardiovascular risk in people with hypertension or coronary heart disease. It belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. Perindopril is taken orally and is quickly converted to its active metabolite, perindoprilat, which works by blocking the enzyme responsible for converting angiotensin I to angiotensin II. By blocking this enzyme, Perindopril helps to regulate blood pressure and maintain a healthy balance of hormones in the body.

Aceonis the brand name

image of different drug pills on a surface

Aceon Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aceon

Perindopril

1993

Approved as Treatment by the FDA

Perindopril, also known as Aceon, is approved by the FDA for 8 uses like Stroke and Congestive heart failure .

Stroke

Used to treat Cerebrovascular Accident in combination with Amlodipine

Congestive heart failure

Helps manage NYHA Class I Congestive heart failure

Heart Attack

Used to treat Myocardial Infarction in combination with Amlodipine

Hypertensive disease

Used to treat High Blood Pressure (Hypertension) in combination with Amlodipine

Hypesthesia

Helps manage chronic heart failure with reduced ejection fraction (NYHA Class III)

Hypesthesia

Helps manage chronic heart failure with reduced ejection fraction (NYHA Class II)

Hypertensive disease

Helps manage Hypertension, Essential Hypertension

perindopril

Used to treat inadequate response on perindopril monotherapy in combination with Amlodipine

Effectiveness

How Aceon Affects PatientsPerindopril is a drug that works by blocking the enzyme (angiotensin II) and hormone system (renin angiotensin aldosterone system, or RAAS) that regulates blood pressure and water balance in the body. It works by inhibiting the conversion of angiotensin I to angiotensin II, which has numerous effects on the body including increasing blood pressure, increasing sodium and water reabsorption from the kidneys, stimulating the secretion of vasopressin, and inducing thirst. Additionally, it prevents the breakdown of bradykinin, a vasodilator which helps further reduce blood

How Aceon works in the bodyACE inhibitors work by blocking an enzyme called ACE. This enzyme has two parts, called N and C domains, which have similar roles. The C domain is mainly responsible for controlling blood pressure, and the N domain helps with stem cell development. Perindopril, the active form of ACE inhibitor, stops ACE from binding to another protein, called ATI. This lowers the amount of ATI in the body, which in turn lowers blood pressure. Perindopril also increases the amount of renin in the body, which can help to regulate blood pressure.

When to interrupt dosage

The measure of Aceon is contingent upon the recognized disorder, for example, Hypertensive disease, Hypesthesia and Hypesthesia. The amount of dosage fluctuates as per the method of delivery (e.g. Tablet or Oral) featured in the table beneath.

Condition

Dosage

Administration

perindopril