← Back to Search

Exercise for Healthy Aging (COMET Trial)

N/A
Recruiting
Led By Eric D Vidoni, PhD
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Reliable means of transportation.
Age 65-80 yrs (inclusive at time of consent)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3 months, 6 months, 12 months
Awards & highlights

COMET Trial Summary

This trial will test whether recommended levels of exercise improve cognition in older adults.

Who is the study for?
This trial is for people aged 65-80 with good cognitive health, confirmed by a medical monitor. Participants must speak and read English, have their own transport, and be medically cleared to exercise. Excluded are those using walking aids, on insulin or certain heart medications, with recent serious health issues like heart attacks or untreated atrial fibrillation, or planning extensive travel.Check my eligibility
What is being tested?
The study investigates the benefits of recommended public health exercises on cognitive function in older adults. It aims to encourage active lifestyles among seniors and inform effective exercise programs that support both physical and mental well-being.See study design
What are the potential side effects?
Since this trial involves standard exercise routines designed for older individuals, side effects might include typical exercise-related discomforts such as muscle soreness or fatigue but should generally be minimal.

COMET Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have a reliable way to get to my appointments.
Select...
I am between 65 and 80 years old.
Select...
I am between 65 and 80 years old.
Select...
I am between 65 and 80 years old.

COMET Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3 months, 6 months, 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3 months, 6 months, 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Global Cognition
Secondary outcome measures
1-Repetition Maximum
Hippocampal volume
Peak oxygen consumption
Other outcome measures
Barriers Self-Efficacy Scale
Blood biomarkers
Blood lactate concentration
+36 more

COMET Trial Design

4Treatment groups
Active Control
Group I: Weight TrainingActive Control1 Intervention
Progressive resistance training 2 days/week, non-consecutive, of 2 sets (10 - 15 repetitions) of 10 exercises (~75 minutes/week). Progression based on repetition completion and 1-repetition maximum. In addition 3 days of Core and Fusion control exercise will also be recommended.
Group II: Core and Fusion TrainingActive Control1 Intervention
150 minutes/week of Core and Fusion exercise, a mix of low impact toning, strengthening, flexibility and balance exercises.
Group III: Combined Endurance and Weight TrainingActive Control1 Intervention
Moderate-intensity endurance training such as brisk walking, 150 minutes/week over 3-5 days. Progression based on a set schedule. Progressive resistance training 2 days/week, non-consecutive, of 2 sets (10 - 15 repetitions) of 10 exercises (~75 minutes/week). Progression based on repetition completion and 1-repetition maximum.
Group IV: Endurance TrainingActive Control1 Intervention
Moderate-intensity endurance training such as brisk walking, 150 minutes/week over 3-5 days. Progression based on a set schedule. In addition 0-2 days of Core and Fusion control exercise will also be recommended.

Find a Location

Who is running the clinical trial?

University of Kansas Medical CenterLead Sponsor
459 Previous Clinical Trials
168,824 Total Patients Enrolled
4 Trials studying Healthy Aging
205 Patients Enrolled for Healthy Aging
Eric D Vidoni, PhDPrincipal InvestigatorUniversity of Kansas Medical Center

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT04848038 — N/A
Healthy Aging Research Study Groups: Weight Training, Core and Fusion Training, Combined Endurance and Weight Training, Endurance Training
Healthy Aging Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT04848038 — N/A
Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT04848038 — N/A
Healthy Aging Patient Testimony for trial: Trial Name: NCT04848038 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How do I qualify to participate in this research?

"In order to qualify for this study, elderly adults must be in good health and within the age range of 65 to 80 years old. Up to 280 patients will be accepted in total."

Answered by AI

How many people are being treated as part of this research?

"That is accurate, the clinical trial in question is still recruiting patients. According to the information on clinicaltrials.gov, which was last updated on 9/6/2022, the study originally began recruitment on 10/14/2021 and is looking for 280 participants at 1 site."

Answered by AI

Are there any patients currently needed for this research?

"That is correct, the clinical trial mentioned is still recruiting patients. According to information on clinicaltrials.gov, the posting date was October 14th 2021 and the most recent update was September 6th 2022. Only 1 site is needed for this study as it enrolling a total of 280 people."

Answered by AI

Are patients who are 45 years or older being accepted into this trial?

"The lower age limit for this clinical trial is 65 years old and the upper age limit is 80 years old."

Answered by AI

Who else is applying?

What state do they live in?
Missouri
Kansas
What site did they apply to?
University of Kansas Alzheimer's Disease Center
What portion of applicants met pre-screening criteria?
Did not meet criteria
Met criteria
How many prior treatments have patients received?
2
1
0

What questions have other patients asked about this trial?

How long is the trial? What kinds of exercise would be appropriate for me?
PatientReceived no prior treatments

Why did patients apply to this trial?

I enjoy these trials. Hx Alzheimer’s disease. I enjoy working on these studies.
PatientReceived 2+ prior treatments
I need to lose weight and get in shape. I have been in a trial before and it was so good for men.
PatientReceived 2+ prior treatments

How responsive is this trial?

Typically responds via
Email
Phone Call
Most responsive sites:
  1. University of Kansas Alzheimer's Disease Center: < 48 hours
Average response time
  • < 2 Days
~77 spots leftby Mar 2025