Aerobid

Asthma
Treatment
20 Active Studies for Aerobid

What is Aerobid

FlunisolideThe Generic name of this drug
Treatment SummaryFlunisolide (AeroBid, Nasalide, Nasarel) is an anti-inflammatory steroid used to treat allergic rhinitis. It works by activating glucocorticoid receptors in the body, which reduces inflammation.
Nasarelis the brand name
Aerobid Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nasarel
Flunisolide
1995
14

Effectiveness

How Aerobid Affects PatientsFlunisolide is a man-made hormone that helps to reduce inflammation and suppress immune responses. It is available as an oral inhaler for asthma or as nasal spray for allergies, and can help reduce common allergy symptoms like sneezing, runny nose, congestion, and throat itching.
How Aerobid works in the bodyFlunisolide is a medication that helps reduce inflammation. It does this by blocking the production of certain molecules that cause inflammation. It also suppresses the immune system, reducing the amount of antibodies and immune cells in the body. Flunisolide works by attaching to a protein in the body called transcortin, which then activates the medication.

When to interrupt dosage

The suggested measure of Aerobid is contingent upon the determined condition. The amount of dosage can be found in the table below, based on the technique of administration (e.g. Aerosol, metered or Nasal).
Condition
Dosage
Administration
Asthma
, 0.25 mg/mL, 0.08 mg, 0.025 %, 0.25 mg, 0.029 mg, 0.25 mg/pump actuation, 0.025 mg/pump actuation, 0.025 mg/dose
Solution, , Nasal, Solution - Nasal, Spray, metered, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray - Nasal, Spray, Solution; Spray, Respiratory (inhalation), Solution; Spray - Nasal

Warnings

Aerobid has two contraindications and should not be taken when encountering the circumstances detailed in the following table.Aerobid Contraindications
Condition
Risk Level
Notes
Status Asthmaticus
Do Not Combine
Asthma
Do Not Combine
There are 20 known major drug interactions with Aerobid.
Common Aerobid Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Flunisolide is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Flunisolide is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Flunisolide is combined with Abatacept.
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Flunisolide.
Abetimus
Major
The risk or severity of adverse effects can be increased when Flunisolide is combined with Abetimus.

Aerobid Novel Uses: Which Conditions Have a Clinical Trial Featuring Aerobid?

150 active trials are currently assessing the potential of Aerobid to alleviate Asthma symptoms.
Condition
Clinical Trials
Trial Phases
Asthma
92 Actively Recruiting
Phase 1, Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 3

Aerobid Reviews: What are patients saying about Aerobid?

5Patient Review
10/22/2010
Aerobid for Asthma Prevention
I've been using this medication for 15 years and it's always given me the best results. I've tried switching to other, more recent drugs but they never work as well as this one does.
5Patient Review
10/30/2007
Aerobid for Asthma
5Patient Review
7/21/2010
Aerobid for Severe Chronic Obstructed Lung Disease
This medication has really helped me out by allowing me to do things I couldn't before. The only downside is that my pharmacy has trouble getting it in stock.
4.3Patient Review
5/4/2009
Aerobid for Asthma
I was using Intal and Aerobid, but my doctor switched me to Advair in 2003. I finally convinced them to switch me back last September, and I haven't had pneumonia since. The taste can be bad, but using a chamber with the Aerobid helps mitigate that
1.7Patient Review
2/4/2009
Aerobid for Asthma
The taste of this medication is beyond words, and unfortunately it has not done much to help with my coughing at night. I will continue using it as prescribed, but it's honestly a struggle because of how terrible it tastes.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aerobid

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Flunisolide inhaler used for?

"This medication is intended to help manage asthma symptoms and improve lung function. It will not work to stop an asthma attack that has already begun."

Answered by AI

What is the generic name for aerobid?

"The brand name Flovent Diskus is no longer available in the U.S.

Generic versions may be available.

This medication is used to treat the symptoms of asthma. It helps to decrease inflammation in the airways. This makes it easier to breathe.

Flunisolide is a medication used to treat the symptoms of asthma by decreasing the inflammation in the airways."

Answered by AI

What is aerobid used for?

"This drug is a type of corticosteroid. It works by reducing swelling and irritation in the lungs, making it easier to breathe. You must use this medication regularly to prevent attacks of wheezing or shortness of breath."

Answered by AI

Clinical Trials for Aerobid

Have you considered Aerobid clinical trials? We made a collection of clinical trials featuring Aerobid, we think they might fit your search criteria.Go to Trials
Image of Allergy Immunology Associates in Mayfield Heights, United States.

Osteopathic Manipulative Treatment for Asthma

18 - 60
All Sexes
Mayfield Heights, OH
Asthma is a common respiratory condition that can be difficult to control despite the use of medications such as inhalers, oral steroids or even injectable medications. Osteopathic Manipulative Treatment (OMT) is a hands-on technique used to improve the chest structure and function and may help in improving breathing. Previous research showed that OMT in asthma patients, can improve the movement of the ribs and improve the "peak flow" which is the maximum rate at which a person can exhale air after taking a deep breath. However, no studies have evaluated the impact of OMT on lung inflammation. This single-site research study at University Hospitals aims to evaluate whether Osteopathic Manipulative Treatment (OMT) can reduce lung inflammation and improve breathing and lung function in adult patients with asthma. The lung function will be evaluated by Spirometry which is a test that measures how much air you can breathe in and out of your lungs, as well as how quickly and easily you can exhale air. The lung inflammation will be measured using a device that can detect how much you are breathing out Nitric Oxide which is a gas produced by inflamed cells in the lungs, this test is called: Fractional exhaled Nitric Oxide or FeNO. Approximately 100 participants will be enrolled.
Waitlist Available
Has No Placebo
Allergy Immunology AssociatesNancy Wasserbauer-Kingston, DO
Image of DARTNet Institute in Aurora, United States.

Inhaled Corticosteroids + Azithromycin for Asthma

13 - 75
All Sexes
Aurora, CO
While asthma therapy is becoming more individualized based on asthma phenotypes, more research is needed to tailor newer therapies to individuals. Inhaled corticosteroid (ICS) medications are the foundation of care for all individuals with persistent asthma. But ICS use is not without possible long term side effects. This study will compare two currently available approaches to reduce AEX in primary care patients: (1) use of inhaled corticosteroids (ICS) as part of rescue therapy, also known as MART (Maintenance And Reliever Therapy) or PARTICS (Patient Activated Reliever Trigger Inhaled Corticosteriods) therapy - either of these therapies will be called Rescue-Inhaled Corticosteroids or R-ICS pronounced "Ricks," and (2) use of azithromycin (AZ) as a preventive therapy. These treatments will be studied both individually and in combination.
Phase 4
Recruiting
DARTNet Institute (+12 Sites)Wilson D Pace, MD, FAAFP
Image of Medical Place Pharmacy in Ajax, Canada.

Pharmacy Support System for Asthma

Any Age
All Sexes
Ajax, Canada
The goal of this study is to assess the effect of an electronic asthma management system in pharmacies (eAMS-Pharm) on asthma control assessment, asthma medication adjustment, asthma action plan delivery, and prompting for specialist referral in severe asthma. The study assesses the differences on pharmacy processes (affecting both the pharmacy team and patients) and pharmacy-delivered care using an interrupted time-series analysis (six-months before vs. six-months after the introduction of eAMS-Pharm in study pharmacy sites). The eAMS-Pharm uses patient data (asthma control, asthma flare-up risk, and current medications) to provide clinical decision support to pharmacists, empowering them to bridge existing gaps between guideline-recommended asthma care and patient care received.
Waitlist Available
Has No Placebo
Medical Place Pharmacy (+2 Sites)
Image of St. Paul's Hospital in Vancouver, Canada.

Salbutamol for Athletic Performance

18 - 55
All Sexes
Vancouver, Canada
β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972. Research has shown non-asthmatics receive no benefit from these drugs at therapeutic dosages; however, many elite athletes still use them, and asthmatic athletes often win more Olympic medals. In some non-asthmatics, β2-agonists may improve breathing limitations during high intensity exercise, which may improve performance. Therefore, we aim to examine if there is a select group of non-asthmatic individuals who experience breathing limitations that may receive benefit from β2-agonists.
Waitlist Available
Paid Trial
St. Paul's HospitalJordan A Guenette, PhD
Have you considered Aerobid clinical trials? We made a collection of clinical trials featuring Aerobid, we think they might fit your search criteria.Go to Trials
Image of Velocity Clinical Research, Mobile in Mobile, United States.

PF-07275315 for Asthma

18 - 70
All Sexes
Mobile, AL
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected. This study is seeking participants who: * Are 18 to 70 years old * Have had moderate-to-severe asthma for at least 12 months that is not well controlled * Have been taking their regular maintenance treatment(s) for asthma over the last 12 months All participants will receive PF-07275315 or a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. PF-07275315 or placebo will be given as multiple shots in the clinic over the course of 12 weeks. We will compare the experiences of people receiving PF-07275315 to those of the people who do not. This will help us determine if PF-07275315 is safe and effective. Participants will be involved in this study for about 9.5 months. During this time, they will have 10 visits at the study clinic.
Phase 2
Recruiting
Velocity Clinical Research, Mobile (+10 Sites)Pfizer CT.gov Call CenterPfizer
Image of St. Joseph's Healthcare Hamilton in Hamilton, Canada.

Corticosteroids for Asthma

18+
All Sexes
Hamilton, Canada
Most individuals with asthma can effectively manage their symptoms and maintain normal lung function using inhaled medications, unfortunately, there is a subset of asthma sufferers whose symptoms, lung function, and risk of asthma attacks remain unimproved despite conventional inhaled medications. There could be several reasons for this. One possibility is that inhaled medications fail to reach the intended areas within the lungs, due to structural abnormalities within the airways themselves. Much like road conditions or closures can impede the speed and efficiency of vehicle travel, factors such as airway narrowing or mucus blockages, which are common in asthma, can obstruct the passage of inhaled medications through the airways. Our team has now optimized advanced medical imaging techniques, including magnetic resonance imaging (MRI) and computed tomography (CT), required to investigate this. This study will use these imaging methods to visually assess and measure individual patients' airways and determine whether abnormal airway structures impact how well they respond to inhaled and orally delivered medications. We anticipate finding that abnormal airway structures make inhaled medications less effective, but that they do not affect the response to oral medications.
Phase 4
Recruiting
St. Joseph's Healthcare Hamilton (+1 Sites)
Have you considered Aerobid clinical trials? We made a collection of clinical trials featuring Aerobid, we think they might fit your search criteria.Go to Trials
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