Atrovent Hfa

Allergic Rhinitis, Bronchial Spasm, Asthma + 8 more
Treatment
1 FDA approval
20 Active Studies for Atrovent Hfa

What is Atrovent Hfa

IpratropiumThe Generic name of this drug
Treatment SummaryIpratropium is a medication used to treat breathing problems caused by narrowing of the airways. It works by blocking a specific type of nerve receptor and relaxing the airways, allowing for easier breathing. Ipratropium was first approved by the FDA in 1986 and is available as a single medication or in combination with albuterol. It is administered through inhalation, which allows it to work locally without being absorbed into the bloodstream.
Atroventis the brand name
image of different drug pills on a surface
Atrovent Hfa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Atrovent
Ipratropium
1986
115

Approved as Treatment by the FDA

Ipratropium, otherwise known as Atrovent, is approved by the FDA for 1 uses such as Chronic Obstructive Pulmonary Disease .
Chronic Obstructive Pulmonary Disease
Used to treat Chronic Obstructive Pulmonary Disease (COPD) in combination with Salbutamol

Effectiveness

How Atrovent Hfa Affects PatientsIpratropium is a medication that helps to open up the airways in the lungs, making it easier to breathe and reducing wheezing and chest tightness. Its effect starts about 1-2 hours after taking it, and lasts for about 4-6 hours. In clinical studies, it has been shown to improve breathing in those suffering from asthma attacks, but taking it regularly or before an attack is not proven to be beneficial.
How Atrovent Hfa works in the bodyIpratropium blocks the effects of the parasympathetic nervous system in the airways, resulting in bronchial dilation and less mucus production. It does this by blocking the release of acetylcholine, a chemical that causes the airway muscles to contract and narrow. By blocking this chemical, the airways stay relaxed, allowing more air to flow through them.

When to interrupt dosage

The advocated dosage of Atrovent Hfa is contingent upon the ascertained condition, such as Chronic Obstructive Pulmonary Disease (COPD), Asthma and Non-Allergic Rhinitis. The quantity of dosage fluctuates, in accordance with the administration technique featured in the table below.
Condition
Dosage
Administration
Chronic Obstructive Pulmonary Disease
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Non-Allergic Rhinitis
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Emphysema
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Bronchitis, Chronic
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Rhinitis, Allergic
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Chronic Obstructive Airway Disease
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Allergic Rhinitis
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Bronchial Spasm
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Asthma
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Nasal Congestion Associated With the Common Cold
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)
Asthma
, 0.5 mg/mL, 0.021 mg, 0.042 mg, 0.017 mg, 0.5 mg, 0.02 mg, 0.018 mg, 0.25 mg/mL, 0.125 mg/mL, 0.3 mg/mL, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.021 mg/pump actuation
, Respiratory (inhalation), Solution, Solution - Respiratory (inhalation), Spray, metered, Nasal, Spray, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Spray, Spray - Nasal, Liquid, Liquid - Respiratory (inhalation), Nasal; Respiratory (inhalation), Solution - Nasal, Aerosol, Aerosol - Nasal; Respiratory (inhalation), Solution - Nasal; Respiratory (inhalation), Spray, metered - Respiratory (inhalation), Inhalant, Inhalant - Respiratory (inhalation), Spray - Respiratory (inhalation)

Warnings

Atrovent Hfa Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Atrovent Hfa.
Common Atrovent Hfa Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Ipratropium is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Glycopyrronium.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Ipratropium.
Atrovent Hfa Toxicity & Overdose RiskThe toxic dose of ipratropium in mice, when taken orally, is 1500mg/kg. The chances of overdosing on ipratropium are low due to its poor absorption rate. Studies have also not found any evidence that ipratropium can cause cancer, birth defects, or gene mutation. High doses of ipratropium, however, may lower fertility rates.
image of a doctor in a lab doing drug, clinical research

Atrovent Hfa Novel Uses: Which Conditions Have a Clinical Trial Featuring Atrovent Hfa?

282 active trials are currently in progress to assess the utility of Atrovent Hfa in managing Asthma, Bronchospasm and Perennial Allergic Rhinitis (PAR).
Condition
Clinical Trials
Trial Phases
Chronic Obstructive Airway Disease
0 Actively Recruiting
Asthma
86 Actively Recruiting
Phase 4, Early Phase 1, Phase 2, Not Applicable, Phase 1, Phase 3
Chronic Obstructive Pulmonary Disease
84 Actively Recruiting
Phase 3, Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4
Bronchial Spasm
0 Actively Recruiting
Bronchitis, Chronic
0 Actively Recruiting
Asthma
0 Actively Recruiting
Allergic Rhinitis
0 Actively Recruiting
Rhinitis, Allergic
0 Actively Recruiting
Emphysema
4 Actively Recruiting
Phase 2, Not Applicable
Nasal Congestion Associated With the Common Cold
0 Actively Recruiting
Non-Allergic Rhinitis
0 Actively Recruiting

Atrovent Hfa Reviews: What are patients saying about Atrovent Hfa?

5Patient Review
12/18/2010
Atrovent Hfa for Chronic Obstructive Lung Disease
Though I experienced some adverse effects like tingling and numbness in my extremities, this treatment did help relieve my labored breathing.
5Patient Review
5/31/2015
Atrovent Hfa for Asthma
I've been using this inhaler for years, and it's really helped me. Suddenly, my insurance won't cover the cost anymore. I went a week without it and had a lot of trouble breathing.
5Patient Review
2/24/2012
Atrovent Hfa for Asthma
I've been using this for the last three months to help with a dry cough that was caused by mucus going down into my stomach. I've also been taking Rabeprazole (a small yellow tablet) twice daily, and it seems to be working. However, I'm concerned about the potential long-term side effects of using this spray, such as a dry mouth or pain in the sinus area. Are there any other people out there who have used this treatment for an extended period of time?
5Patient Review
4/19/2011
Atrovent Hfa for Emphysema
I've only been using this inhaler for five weeks, and I've already noticed a huge difference in my breathing. The coughing has also almost completely stopped.
5Patient Review
12/18/2010
Atrovent Hfa for Chronic Obstructive Lung Disease
After the emergency doctor had me take this medication, I experienced tingling and numbness in my hands and face, chest pains, lots of coughing, and a sore throat. These effects lasted for about 24 hours. However, this did relieve my labored breathing.
View All Reviews
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Patient Q&A Section about atrovent hfa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Atrovent HFA a rescue inhaler?

"Ipratropium bromide is a drug used to help keep airways open. It is not a rescue medication and takes about 15 minutes to start working."

Answered by AI

Is Atrovent a steroid inhaler?

"Atrovent is not a steroid. It is an anticholinergic, which is a medication that works differently than steroids to treat runny nose and allergies."

Answered by AI

Is Atrovent the same as albuterol?

"Atrovent and albuterol treat different conditions by relaxing airway muscles in different ways. Albuterol works faster so it should be used first if difficulty breathing or COPD attack is experienced."

Answered by AI

What is Atrovent HFA inhaler used for?

"Ipratropium is a medication used to relieve symptoms of COPD such as wheezing and shortness of breath. It works by relaxing the muscles in the airways to ease breathing."

Answered by AI

Clinical Trials for Atrovent Hfa

Have you considered Atrovent Hfa clinical trials? We made a collection of clinical trials featuring Atrovent Hfa, we think they might fit your search criteria.
Have you considered Atrovent Hfa clinical trials? We made a collection of clinical trials featuring Atrovent Hfa, we think they might fit your search criteria.
Have you considered Atrovent Hfa clinical trials? We made a collection of clinical trials featuring Atrovent Hfa, we think they might fit your search criteria.
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