Atrovent Hfa

Asthma, Non-Allergic Rhinitis, Chronic Obstructive Pulmonary Disease + 8 more
Treatment
1 FDA approval
20 Active Studies for Atrovent Hfa

What is Atrovent Hfa

IpratropiumThe Generic name of this drug
Treatment SummaryIpratropium is a medication used to treat breathing problems caused by narrowing of the airways. It works by blocking a specific type of nerve receptor and relaxing the airways, allowing for easier breathing. Ipratropium was first approved by the FDA in 1986 and is available as a single medication or in combination with albuterol. It is administered through inhalation, which allows it to work locally without being absorbed into the bloodstream.
Atroventis the brand name
Atrovent Hfa Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Atrovent
Ipratropium
1986
113

Approved as Treatment by the FDA

Ipratropium, otherwise known as Atrovent, is approved by the FDA for 1 uses such as Chronic Obstructive Pulmonary Disease .
Chronic Obstructive Pulmonary Disease
Used to treat Chronic Obstructive Pulmonary Disease (COPD) in combination with Salbutamol

Effectiveness

How Atrovent Hfa Affects PatientsIpratropium is a medication that helps to open up the airways in the lungs, making it easier to breathe and reducing wheezing and chest tightness. Its effect starts about 1-2 hours after taking it, and lasts for about 4-6 hours. In clinical studies, it has been shown to improve breathing in those suffering from asthma attacks, but taking it regularly or before an attack is not proven to be beneficial.
How Atrovent Hfa works in the bodyIpratropium blocks the effects of the parasympathetic nervous system in the airways, resulting in bronchial dilation and less mucus production. It does this by blocking the release of acetylcholine, a chemical that causes the airway muscles to contract and narrow. By blocking this chemical, the airways stay relaxed, allowing more air to flow through them.

When to interrupt dosage

The advocated dosage of Atrovent Hfa is contingent upon the ascertained condition, such as Chronic Obstructive Pulmonary Disease (COPD), Asthma and Non-Allergic Rhinitis. The quantity of dosage fluctuates, in accordance with the administration technique featured in the table below.
Condition
Dosage
Administration
Asthma
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Non-Allergic Rhinitis
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Chronic Obstructive Pulmonary Disease
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Chronic Bronchitis
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Nasal Congestion Associated With the Common Cold
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Bronchospasm
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Perennial Allergic Rhinitis (PAR)
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Chronic Obstructive Airway Disease
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Emphysema
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Allergic Rhinitis
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal
Asthma
, 0.25 mg/mL, 0.125 mg/mL, 0.5 mg/mL, 0.02 mg, 0.3 mg/mL, 0.042 mg, 0.021 mg, 0.017 mg, 0.021 mg/pump actuation, 0.042 mg/pump actuation, 0.02 mg/pump actuation, 0.5 mg, 0.018 mg
Solution - Respiratory (inhalation), , Respiratory (inhalation), Liquid, Nasal; Respiratory (inhalation), Solution, Aerosol, metered - Respiratory (inhalation), Spray, Spray, metered, Aerosol, Spray, metered - Nasal, Nasal, Liquid - Respiratory (inhalation), Solution - Nasal, Spray - Respiratory (inhalation), Aerosol, metered, Solution - Nasal; Respiratory (inhalation), Aerosol - Nasal; Respiratory (inhalation), Inhalant, Spray, metered - Respiratory (inhalation), Inhalant - Respiratory (inhalation), Spray - Nasal

Warnings

Atrovent Hfa Contraindications
Condition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
There are 20 known major drug interactions with Atrovent Hfa.
Common Atrovent Hfa Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Ipratropium is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Ipratropium is combined with Glycopyrronium.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Ipratropium.
Atrovent Hfa Toxicity & Overdose RiskThe toxic dose of ipratropium in mice, when taken orally, is 1500mg/kg. The chances of overdosing on ipratropium are low due to its poor absorption rate. Studies have also not found any evidence that ipratropium can cause cancer, birth defects, or gene mutation. High doses of ipratropium, however, may lower fertility rates.

Atrovent Hfa Novel Uses: Which Conditions Have a Clinical Trial Featuring Atrovent Hfa?

282 active trials are currently in progress to assess the utility of Atrovent Hfa in managing Asthma, Bronchospasm and Perennial Allergic Rhinitis (PAR).
Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
93 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Asthma
157 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Asthma
1 Actively Recruiting
Phase 2
Perennial Allergic Rhinitis (PAR)
0 Actively Recruiting
Allergic Rhinitis
14 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 1, Phase 4
Nasal Congestion Associated With the Common Cold
0 Actively Recruiting
Emphysema
13 Actively Recruiting
Phase 3, Phase 4, Early Phase 1, Phase 1, Phase 2, Not Applicable
Chronic Bronchitis
6 Actively Recruiting
Not Applicable, Phase 3, Phase 2
Non-Allergic Rhinitis
0 Actively Recruiting
Chronic Obstructive Airway Disease
0 Actively Recruiting
Bronchospasm
0 Actively Recruiting

Atrovent Hfa Reviews: What are patients saying about Atrovent Hfa?

5Patient Review
12/18/2010
Atrovent Hfa for Chronic Obstructive Lung Disease
Though I experienced some adverse effects like tingling and numbness in my extremities, this treatment did help relieve my labored breathing.
5Patient Review
5/31/2015
Atrovent Hfa for Asthma
I've been using this inhaler for years, and it's really helped me. Suddenly, my insurance won't cover the cost anymore. I went a week without it and had a lot of trouble breathing.
5Patient Review
2/24/2012
Atrovent Hfa for Asthma
I've been using this for the last three months to help with a dry cough that was caused by mucus going down into my stomach. I've also been taking Rabeprazole (a small yellow tablet) twice daily, and it seems to be working. However, I'm concerned about the potential long-term side effects of using this spray, such as a dry mouth or pain in the sinus area. Are there any other people out there who have used this treatment for an extended period of time?
5Patient Review
4/19/2011
Atrovent Hfa for Emphysema
I've only been using this inhaler for five weeks, and I've already noticed a huge difference in my breathing. The coughing has also almost completely stopped.
5Patient Review
12/18/2010
Atrovent Hfa for Chronic Obstructive Lung Disease
After the emergency doctor had me take this medication, I experienced tingling and numbness in my hands and face, chest pains, lots of coughing, and a sore throat. These effects lasted for about 24 hours. However, this did relieve my labored breathing.
5Patient Review
2/24/2012
Atrovent Hfa for Asthma
I've been using this for the last three months to address a dry cough, and it seems to be working. I'm a little worried about long-term side effects, but so far so good.
5Patient Review
4/19/2011
Atrovent Hfa for Emphysema
This inhaler has been a huge help to me. I started using it five weeks ago and simultaneously quit smoking. In just two weeks, I saw a significant improvement in my breathing and coughing.
5Patient Review
5/31/2015
Atrovent Hfa for Asthma
I've been using this inhaler for over 15 years, and it's really helped me. Suddenly, my insurance won't cover the cost, and I had to go a week without it. In that time, I really struggled to breathe.
4.3Patient Review
7/13/2013
Atrovent Hfa for Asthma
Xopenex/albuterol worked better and faster, but I developed vertigo, headaches and other side effects. Spiriva worked well, but kept me awake, so my doctor suggested Atrovent and it's great. I take inhaled steroids and use Atrovent when I exercise as well as every day. It stops my coughing and I have no side effects. The only time I needed to use Xopenex too was when I caught a chest cold.
4.3Patient Review
10/24/2010
Atrovent Hfa for Emphysema
4.3Patient Review
10/24/2010
Atrovent Hfa for Emphysema
4.3Patient Review
4/20/2011
Atrovent Hfa for Emphysema
I've been using this medication for 16 years now, and I'm noticing that the side effects are getting worse and worse each day.
4.3Patient Review
2/6/2012
Atrovent Hfa for Bronchitis
I use two puffs of this twice a day, and it's been hugely effective in reducing the whistling noise in my ears.
4.3Patient Review
2/6/2012
Atrovent Hfa for Bronchitis
I've been using this medication for a little over a year now, taking two puffs twice daily. It's helped to significantly reduce the ringing in my ears.
4.3Patient Review
4/20/2011
Atrovent Hfa for Emphysema
I've been using this drug for 16 years now, and I'm noticing that the side effects are worsening.
4.3Patient Review
7/13/2013
Atrovent Hfa for Asthma
Xopenex/albuterol works better and faster, but I developed vertigo, headaches, and other side effects. Spiriva worked well but kept me awake, so my doctor suggested Atrovent instead and it's great! I take inhaled steroids every day as well as use Atrovent when I exercise; it stops my coughing with no side effects. The only time I needed to use Xopenex was when I caught a chest cold.
4Patient Review
2/15/2010
Atrovent Hfa for Asthma
4Patient Review
2/15/2010
Atrovent Hfa for Asthma
3.7Patient Review
9/23/2020
Atrovent Hfa for Chronic Obstructive Lung Disease
I have to use this inhaler more frequently than the directions indicate I should, but it's still effective for me. Just something to be aware of if you're considering this treatment.
3.7Patient Review
9/23/2020
Atrovent Hfa for Chronic Obstructive Lung Disease
Though the inhaler is supposed to have 200 doses, I find that I go through it much faster. The medication still works well for me, but be aware that you may need to replace your inhaler more often than expected.
3.3Patient Review
1/14/2011
Atrovent Hfa for Chronic Obstructive Lung Disease
When I took this as directed--two puffs, four times a day--I experienced an alarming increase in heart rate. Additionally, there was a weird taste that lingered on my tongue for hours, even after rinsing. Cutting back to one puff three or four times daily eliminated the fast heart beat issue; however, there still sometimes is a strange taste left behind even if I don't rinse immediately after taking the medication.
3.3Patient Review
1/14/2011
Atrovent Hfa for Chronic Obstructive Lung Disease
I found that when I cut the dosage down, this medication didn't have as many negative side-effects.
3Patient Review
12/17/2019
Atrovent Hfa for Emphysema
Atrovent HFA may be a good product, but it is very expensive. My last inhaler ran out after only four uses, which cost me $64. The new doctor is changing me to a nebulizer, which only costs $8. I'm looking forward to trying it next week.
3Patient Review
6/19/2012
Atrovent Hfa for Chronic Obstructive Lung Disease
I'm finding it tough to keep up with the 16-puff-per-day prescription. I've read that you shouldn't take more than 12 puffs per day, but my doctor says otherwise. Not sure what to make of this discrepancy..
3Patient Review
12/17/2019
Atrovent Hfa for Emphysema
Atrovent HFA is a good product, however it is very expensive. My last inhaler skipped from 20 doses to zero in four doses. Thatâ??s $64 in medicine, gone (16 doses at $4 each). My new doctor is changing me to a nebulizer ($40 online). The new Rx is $8. EIGHT DOLLARS. 1/100th of Atrovent.
3Patient Review
6/19/2012
Atrovent Hfa for Chronic Obstructive Lung Disease
It's tough for me to keep up with the 16 puffs per day that my doctor prescribed. I've read that you shouldn't take more than 12 puffs a day, so I'm not sure what to make of the discrepancy.
2.7Patient Review
5/8/2013
Atrovent Hfa for Bronchitis
I felt very dizzy and my vision was blurred after taking this medication. Additionally, I experienced heaviness in my legs.
2.7Patient Review
5/8/2013
Atrovent Hfa for Bronchitis
I felt very heavy in my legs and dizzy, and my vision was blurred.
1Patient Review
8/5/2017
Atrovent Hfa for Asthma
The taste was really unpleasant. It's like if you shot vodka into your mouth--just terrible.
1Patient Review
8/5/2017
Atrovent Hfa for Asthma
The taste was really unpleasant. It's like a shot of vodka mixed with air.

Patient Q&A Section about atrovent hfa

Is Atrovent HFA a rescue inhaler?

"Ipratropium bromide is a drug used to help keep airways open. It is not a rescue medication and takes about 15 minutes to start working." - Anonymous Online Contributor

Unverified Answer

Is Atrovent a steroid inhaler?

"Atrovent is not a steroid. It is an anticholinergic, which is a medication that works differently than steroids to treat runny nose and allergies." - Anonymous Online Contributor

Unverified Answer

Is Atrovent the same as albuterol?

"Atrovent and albuterol treat different conditions by relaxing airway muscles in different ways. Albuterol works faster so it should be used first if difficulty breathing or COPD attack is experienced." - Anonymous Online Contributor

Unverified Answer

What is Atrovent HFA inhaler used for?

"Ipratropium is a medication used to relieve symptoms of COPD such as wheezing and shortness of breath. It works by relaxing the muscles in the airways to ease breathing." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Atrovent Hfa

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Have you considered Atrovent Hfa clinical trials? We made a collection of clinical trials featuring Atrovent Hfa, we think they might fit your search criteria.
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