<p>Bentyl and <a href="https://www.withpower.com/clinical-trials/viberzi">Viberzi</a> are two different types of drugs. Bentyl is an anticholinergic and Viberzi is a mu-opioid receptor agonist.</p>

Bentyl

Irritable Bowel Syndrome, Intestines, gastrointestinal cramps caused by Gas

Treatment

4 FDA approvals

6 Active Studies for Bentyl

Treatment for

Irritable Bowel Syndrome

What is Bentyl

DicyclomineThe Generic name of this drug

Treatment SummaryDicyclomine is a medication used to treat cramps and spasms of the intestines caused by irritable bowel syndrome or functional bowel disorder. It blocks certain natural substances in the body to reduce muscle contractions. Despite common prescription, there is limited evidence to support its effectiveness. Dicyclomine was approved by the FDA in 1950.

Bentylis the brand name

image of different drug pills on a surface

Bentyl Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Bentyl

Dicyclomine

1950

217

Approved as Treatment by the FDA

Dicyclomine, also known as Bentyl, is approved by the FDA for 4 uses which include Bowel; Functional Syndrome and Irritable Bowel Syndrome (IBS) .

Bowel; Functional Syndrome

Irritable Bowel Syndrome (IBS)

Intestines

Irritable Bowel Syndrome

Effectiveness

How Bentyl Affects PatientsDicyclomine is a medication used to relax the muscles of the digestive system. It should be taken four times per day, with doses of 20-40mg orally or 10-20mg by injection. Do not take this drug intravenously.

How Bentyl works in the bodyDicyclomine works by blocking the action of certain chemicals that cause muscles to spasm. It blocks some receptors, as well as bradykinin and histamine, which are chemicals that cause muscle contractions. By blocking them, the muscle spasms are reduced.

When to interrupt dosage

The measure of Bentyl relies upon the identified malady, including Irritable Bowel Syndrome (IBS), gastrointestinal spasms caused by Gas and Intestines. The magnitude of dosage can be found in the table beneath, contingent upon the mode of administration.

Condition

Dosage

Administration

Irritable Bowel Syndrome

20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg

, Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral, Intramuscular, Injection, Injection - Intramuscular, Syrup, Syrup - Oral, Injection, solution, Injection, solution - Intramuscular, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Tablet, extended release, Tablet, extended release - Oral

Intestines

20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg

gastrointestinal cramps caused by Gas

20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg

Warnings

Bentyl Contraindications

Condition

Risk Level

Notes

Myasthenia Gravis

Do Not Combine

Reflux Esophagitis (RE)

Do Not Combine

Cardiovascular Physiological Phenomena

Do Not Combine

Arterial Occlusive Diseases

Do Not Combine

Pulse Frequency

Do Not Combine

Ulcerative Colitis

Do Not Combine

Uropathy Obstructive

Do Not Combine

Open-angle glaucoma

Do Not Combine

There are 20 known major drug interactions with Bentyl.

Common Bentyl Drug Interactions

Drug Name

Risk Level

Description

Aclidinium

Major

The risk or severity of adverse effects can be increased when Dicyclomine is combined with Aclidinium.

Cimetropium

Major

The risk or severity of adverse effects can be increased when Dicyclomine is combined with Cimetropium.

Eluxadoline

Major

The risk or severity of constipation can be increased when Dicyclomine is combined with Eluxadoline.

Glycopyrronium

Major

The risk or severity of adverse effects can be increased when Dicyclomine is combined with Glycopyrronium.

Ipratropium

Major

The risk or severity of adverse effects can be increased when Dicyclomine is combined with Ipratropium.

Bentyl Toxicity & Overdose RiskIndividuals who have taken too much of this drug may have a headache, vomiting, blurry vision, enlarged pupils, dizziness, dry mouth, difficulty swallowing, and feeling overly excited. They may also have hot, dry skin. Treatment for overdose includes stomach pumping, vomiting, activated charcoal, sedatives for excitement, and an agent to help with muscle control if necessary. The lowest toxic dose in mice is 625mg/kg.

image of a doctor in a lab doing drug, clinical research

Bentyl Novel Uses: Which Conditions Have a Clinical Trial Featuring Bentyl?

A total of 5 trials are assessing the potential of Bentyl to alleviate Irritable Bowel Syndrome (IBS), Gastrointestinal Cramps and Intestinal Disorders.

Condition

Clinical Trials

Trial Phases

Intestines

0 Actively Recruiting

gastrointestinal cramps caused by Gas

0 Actively Recruiting

Irritable Bowel Syndrome

6 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Early Phase 1

Bentyl Reviews: What are patients saying about Bentyl?

5Patient Review

1/25/2017

Bentyl for Irritable Colon

Unfortunately, this medication made my IBS-D worse. I experienced more intestinal pain and irregularity.

5Patient Review

1/20/2018

Bentyl for Irritable Colon

This medication has been greatly helping my irritable bowl syndrome, but I am concerned about long-term side effects.

5Patient Review

8/20/2018

Bentyl for Irritable Colon

I've been taking this medication for two years now, since I had to get a stool transplant for c diff. My IBS has gotten worse since then, but this drug really helps me manage it. The doctor recently upped my dosage, which has resulted in a few more side effects like dizziness and drowsiness; however, it's still working pretty well for me overall.

5Patient Review

7/27/2016

Bentyl for Irritable Colon

This medication has been a lifesaver for me. I have IBS-C and it really helps to stop the pain and spasms without causing constipation like other medications I've tried.

5Patient Review

7/23/2016

Bentyl for Irritable Colon

I use this for stomach cramps and it works great. The only weird side effect is that my lips and face start tingling, but it's not uncomfortable or anything.

View All Reviews

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Patient Q&A Section about bentyl

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Bentyl supposed to do?

"This medication can help reduce the symptoms of stomach and intestinal cramping by slowing the natural movements of the gut and relaxing the muscles in the stomach and intestines."

Answered by AI

Is Bentyl a muscle relaxer?

"Bentyl is a type of drug known as an anticholinergic. It is an antispasmodic that prevents spasms in the muscles of the gut and bladder by causing those muscles to relax. It also reduces the amount of acid that is produced in the stomach."

Answered by AI

Is Bentyl an opioid?

"Bentyl and Viberzi are two different types of drugs. Bentyl is an anticholinergic and Viberzi is a mu-opioid receptor agonist."

Answered by AI

What are the side effects of Bentyl?

"A person may experience dry mouth, blurred vision, dry eyes, confusion, agitation, increased heart rate, constipation, difficulty urinating, and headaches when they are dehydrated."

Answered by AI