Bentyl

Irritable Bowel Syndrome (IBS), Intestines, gastrointestinal cramps caused by Gas
Treatment
2 FDA approvals
9 Active Studies for Bentyl

What is Bentyl

DicyclomineThe Generic name of this drug
Treatment SummaryDicyclomine is a medication used to treat cramps and spasms of the intestines caused by irritable bowel syndrome or functional bowel disorder. It blocks certain natural substances in the body to reduce muscle contractions. Despite common prescription, there is limited evidence to support its effectiveness. Dicyclomine was approved by the FDA in 1950.
Bentylis the brand name
image of different drug pills on a surface
Bentyl Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bentyl
Dicyclomine
1950
217

Approved as Treatment by the FDA

Dicyclomine, also known as Bentyl, is approved by the FDA for 2 uses which include Intestines and Irritable Bowel Syndrome (IBS) .
Intestines
Irritable Bowel Syndrome (IBS)

Effectiveness

How Bentyl Affects PatientsDicyclomine is a medication used to relax the muscles of the digestive system. It should be taken four times per day, with doses of 20-40mg orally or 10-20mg by injection. Do not take this drug intravenously.
How Bentyl works in the bodyDicyclomine works by blocking the action of certain chemicals that cause muscles to spasm. It blocks some receptors, as well as bradykinin and histamine, which are chemicals that cause muscle contractions. By blocking them, the muscle spasms are reduced.

When to interrupt dosage

The measure of Bentyl relies upon the identified malady, including Irritable Bowel Syndrome (IBS), gastrointestinal spasms caused by Gas and Intestines. The magnitude of dosage can be found in the table beneath, contingent upon the mode of administration.
Condition
Dosage
Administration
gastrointestinal cramps caused by Gas
20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral, Intramuscular, Injection, Injection - Intramuscular, Syrup, Syrup - Oral, Injection, solution, Injection, solution - Intramuscular, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Tablet, extended release, Tablet, extended release - Oral
Intestines
20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral, Intramuscular, Injection, Injection - Intramuscular, Syrup, Syrup - Oral, Injection, solution, Injection, solution - Intramuscular, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Tablet, extended release, Tablet, extended release - Oral
Irritable Bowel Syndrome (IBS)
20.0 mg, , 10.0 mg, 10.0 mg/mL, 20.6 mg, 20.0 mg/mL, 30.0 mg, 2.5 mg, 40.0 mg
, Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Solution, Solution - Oral, Intramuscular, Injection, Injection - Intramuscular, Syrup, Syrup - Oral, Injection, solution, Injection, solution - Intramuscular, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Tablet, extended release, Tablet, extended release - Oral

Warnings

Bentyl Contraindications
Condition
Risk Level
Notes
Myasthenia Gravis
Do Not Combine
Reflux Esophagitis (RE)
Do Not Combine
Cardiovascular Physiological Phenomena
Do Not Combine
Arterial Occlusive Diseases
Do Not Combine
Pulse Frequency
Do Not Combine
Ulcerative Colitis
Do Not Combine
Uropathy Obstructive
Do Not Combine
Open-angle glaucoma
Do Not Combine
There are 20 known major drug interactions with Bentyl.
Common Bentyl Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Dicyclomine is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Dicyclomine is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Dicyclomine is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Dicyclomine is combined with Glycopyrronium.
Ipratropium
Major
The risk or severity of adverse effects can be increased when Dicyclomine is combined with Ipratropium.
Bentyl Toxicity & Overdose RiskIndividuals who have taken too much of this drug may have a headache, vomiting, blurry vision, enlarged pupils, dizziness, dry mouth, difficulty swallowing, and feeling overly excited. They may also have hot, dry skin. Treatment for overdose includes stomach pumping, vomiting, activated charcoal, sedatives for excitement, and an agent to help with muscle control if necessary. The lowest toxic dose in mice is 625mg/kg.
image of a doctor in a lab doing drug, clinical research

Bentyl Novel Uses: Which Conditions Have a Clinical Trial Featuring Bentyl?

A total of 5 trials are assessing the potential of Bentyl to alleviate Irritable Bowel Syndrome (IBS), Gastrointestinal Cramps and Intestinal Disorders.
Condition
Clinical Trials
Trial Phases
Intestines
0 Actively Recruiting
gastrointestinal cramps caused by Gas
0 Actively Recruiting
Irritable Bowel Syndrome (IBS)
9 Actively Recruiting
Not Applicable, Phase 4, Phase 2

Bentyl Reviews: What are patients saying about Bentyl?

5Patient Review
1/25/2017
Bentyl for Irritable Colon
Unfortunately, this medication made my IBS-D worse. I experienced more intestinal pain and irregularity.
5Patient Review
1/20/2018
Bentyl for Irritable Colon
This medication has been greatly helping my irritable bowl syndrome, but I am concerned about long-term side effects.
5Patient Review
8/20/2018
Bentyl for Irritable Colon
I've been taking this medication for two years now, since I had to get a stool transplant for c diff. My IBS has gotten worse since then, but this drug really helps me manage it. The doctor recently upped my dosage, which has resulted in a few more side effects like dizziness and drowsiness; however, it's still working pretty well for me overall.
5Patient Review
7/27/2016
Bentyl for Irritable Colon
This medication has been a lifesaver for me. I have IBS-C and it really helps to stop the pain and spasms without causing constipation like other medications I've tried.
5Patient Review
7/23/2016
Bentyl for Irritable Colon
I use this for stomach cramps and it works great. The only weird side effect is that my lips and face start tingling, but it's not uncomfortable or anything.
4.3Patient Review
4/24/2017
Bentyl for Irritable Colon
I was finally prescribed this medicine after a year of struggling with UC symptoms. I'm so grateful to no longer be in pain.
4Patient Review
10/23/2016
Bentyl for Irritable Colon
This treatment really helped me with the excess gas I was struggling with.
3.7Patient Review
4/24/2018
Bentyl for Irritable Colon
This medication is helpful for pain and diarrhea, but the side effects are not worth it. Blurred vision, dry and red eyes, headaches, extreme fatigue, and agitation are all common complaints. Peppermint oil capsules and calcium carbonate are a better choice.
2.7Patient Review
9/4/2022
Bentyl for Irritable Colon
While this medication did alleviate my initial problems of abdominal pain and diarrhea, the side effects were far too much for me to handle. I experienced a constant headache, fatigue, confusion, brain fog, dizziness, and dry eyes.
2.3Patient Review
10/11/2020
Bentyl for Irritable Colon
I was prescribed this at a low dosage for just one week. However, after only four days of taking it I am now in more pain than before and constipated to boot. This medication clearly does not agree with me and I will never take it again.
2.3Patient Review
2/13/2016
Bentyl for Irritable Colon
1Patient Review
5/22/2019
Bentyl for Irritable Colon
Do not bother with this medication. I found it made my bloating, gas and indigestion worse. If you're looking for relief, try natural methods instead.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about bentyl

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Bentyl supposed to do?

"This medication can help reduce the symptoms of stomach and intestinal cramping by slowing the natural movements of the gut and relaxing the muscles in the stomach and intestines."

Answered by AI

Is Bentyl a muscle relaxer?

"Bentyl is a type of drug known as an anticholinergic. It is an antispasmodic that prevents spasms in the muscles of the gut and bladder by causing those muscles to relax. It also reduces the amount of acid that is produced in the stomach."

Answered by AI

Is Bentyl an opioid?

"Bentyl and Viberzi are two different types of drugs. Bentyl is an anticholinergic and Viberzi is a mu-opioid receptor agonist."

Answered by AI

What are the side effects of Bentyl?

"A person may experience dry mouth, blurred vision, dry eyes, confusion, agitation, increased heart rate, constipation, difficulty urinating, and headaches when they are dehydrated."

Answered by AI

Clinical Trials for Bentyl

Have you considered Bentyl clinical trials? We made a collection of clinical trials featuring Bentyl, we think they might fit your search criteria.