Jalyn

Enlarged Prostate, Prostatic Hyperplasia, Benign Prostatic Hyperplasia
Treatment
5 FDA approvals
20 Active Studies for Jalyn

What is Jalyn

DutasterideThe Generic name of this drug
Treatment SummaryDutasteride, sold under the brand name Avodart, is a medication used to treat benign prostatic hyperplasia (BPH) in men. It works by blocking two types of enzymes (type 1 and type 2 5α-reductase) that convert testosterone into dihydrotestosterone (DHT), which contributes to the enlargement of the prostate gland. Dutasteride was approved by the FDA in 2001 and is as effective as another medication (finasteride) for treating BPH. Dutasteride has also been studied for treating hair loss, but it is not currently approved for this use
Avodartis the brand name
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Jalyn Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Avodart
Dutasteride
2002
57

Approved as Treatment by the FDA

Dutasteride, also called Avodart, is approved by the FDA for 5 uses including Enlarged Prostate and symptomatic benign prostatic hyperplasia (BPH) .
Enlarged Prostate
Helps manage Benign Prostatic Hyperplasia (BPH)
symptomatic benign prostatic hyperplasia (BPH)
Used to treat symptomatic benign prostatic hyperplasia (BPH) in combination with Tamsulosin
Enlarged Prostate
Used to treat Enlarged Prostate in combination with Tamsulosin
Benign Prostatic Hyperplasia
Used to treat symptomatic benign prostatic hyperplasia (BPH) in combination with Tamsulosin
Prostatic Hyperplasia
Used to treat Enlarged Prostate in combination with Tamsulosin

Effectiveness

How Jalyn Affects PatientsDutasteride is a drug that works to lower the levels of a hormone called dihydrotestosterone (DHT) that is found in the body. It can help reduce the size of the prostate gland, improve urinary flow, and ease symptoms of benign prostatic hyperplasia. After taking dutasteride for 1-2 weeks, the amount of DHT in the body is decreased by 85-90%. After taking it for one year, most people have a decrease in DHT of over 90%. Additionally, dutasteride may also reduce the levels of prostate-specific antigen (PSA) in people with
How Jalyn works in the bodyDutasteride reduces the levels of DHT, a hormone linked to prostate growth. It does this by forming a complex with an enzyme in the prostate that converts testosterone into DHT. By binding to this enzyme, it prevents it from doing its job, so the levels of DHT are reduced. Dutasteride is more effective at reducing DHT levels than other drugs, reducing levels by more than 90%. It does not bind to the androgen receptor, but it is a competitive and specific inhibitor of both Type I and Type II 5α-reductase isoenzymes. This means that it prevents the enzyme from

When to interrupt dosage

The suggested dosage of Jalyn is affected by the recognized condition, including Benign Prostatic Hyperplasia, Enlarged Prostate and Enlarged Prostate. The amount of dosage can be found in the table below, contingent upon the technique of delivery (e.g. Capsule or Capsule, extended release - Oral).
Condition
Dosage
Administration
Enlarged Prostate
0.5 mg,
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral
Prostatic Hyperplasia
0.5 mg,
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral
Benign Prostatic Hyperplasia
0.5 mg,
, Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Capsule, Capsule - Oral, Capsule, extended release, Capsule, extended release - Oral

Warnings

Jalyn has three contraindications, and it should not be used in conjunction with the conditions outlined in the following table.Jalyn Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
intended pregnancy
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Jalyn.
Common Jalyn Drug Interactions
Drug Name
Risk Level
Description
Alfuzosin
Major
Dutasteride may increase the hypotensive activities of Alfuzosin.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Dutasteride.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Dutasteride.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Dutasteride.
Carbamazepine
Major
The metabolism of Carbamazepine can be decreased when combined with Dutasteride.
Jalyn Toxicity & Overdose RiskThe toxic dose of dutasteride in rabbits is greater than 2,000 mg/kg. In studies involving people taking a single dose of dutasteride up to 80 times the normal dose, only minor side effects such as reduced libido, impotence, gynecomastia, and ejaculation problems were reported. There is no known antidote for overdose. In animal studies, high doses of dutasteride caused decreased fertility in male rats and signs of non-specific, reversible toxicity in rats and dogs. Pregnant women should not take dutasteride as it may cause harm to male fetuses.

Jalyn Novel Uses: Which Conditions Have a Clinical Trial Featuring Jalyn?

21 active clinical trials are being conducted to assess the potential of Jalyn to treat Enlarged Prostate, Benign Prostatic Hyperplasia and other related conditions.
Condition
Clinical Trials
Trial Phases
Benign Prostatic Hyperplasia
0 Actively Recruiting
Enlarged Prostate
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2
Prostatic Hyperplasia
0 Actively Recruiting

Jalyn Reviews: What are patients saying about Jalyn?

5Patient Review
2/2/2013
Jalyn for Enlarged Prostate
Though it is quite pricey, this medication appears to be doing its job. I wish there was a less expensive generic option available, but as it stands, I have to pay over one hundred dollars every three months.
4.7Patient Review
8/22/2013
Jalyn for Enlarged Prostate
This treatment has been a game-changer for me. I no longer have to self-catheterize, and I can't tell you how much of an improvement that has been in my quality of life.
4.7Patient Review
12/26/2012
Jalyn for Enlarged Prostate
Jalyn is a slow-acting medication, and it's quite expensive compared to its alternatives. However, it is more convenient because you only have to take one pill instead of two.
4.3Patient Review
2/26/2014
Jalyn for Enlarged Prostate
Upon taking one pill for two days in a row, I found that my urinary and bowel functions greatly improved.
4.3Patient Review
5/29/2013
Jalyn for Enlarged Prostate
Jayln gives me heartburn, so I make sure to eat something when I take it.
View All Reviews
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Patient Q&A Section about jalyn

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug Jalyn used for?

"This product is used by men to treat the symptoms of an enlarged prostate. Dutasteride works by reducing the size of the enlarged prostate. Tamsulosin is an alpha-blocker that works by relaxing muscles in the bladder and prostate."

Answered by AI

How much does jalyn cost?

"Jalyn is a medication that is used to treat an enlarged prostate. It works by reducing the amount of a hormone that leads to prostate growth. It also relaxes the muscles in the prostate and bladder, which makes it easier to urinate. The lowest GoodRx price for the most common version of generic Jalyn is around $90.41, 81% off the average retail price of $485.22."

Answered by AI

What is the generic name for jalyn?

"The drug Jalyn, which is a combination of dutasteride and tamsulosin, is now available as a generic medication. This may be a much cheaper option than the brand version of the drug."

Answered by AI

What are the side effects of dutasteride tamsulosin?

"The following side effects may occur: feeling dizzy, lightheaded, or sleepy; having a stuffy or runny nose; having sexual problems; having pain or swelling in the testicles; or having bigger or more tender breasts."

Answered by AI

Clinical Trials for Jalyn

Have you considered Jalyn clinical trials? We made a collection of clinical trials featuring Jalyn, we think they might fit your search criteria.
Have you considered Jalyn clinical trials? We made a collection of clinical trials featuring Jalyn, we think they might fit your search criteria.
Have you considered Jalyn clinical trials? We made a collection of clinical trials featuring Jalyn, we think they might fit your search criteria.
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