Your session is about to expire
What is Chlorpheniramine Maleate
Dexchlorpheniramine maleateThe Generic name of this drug
Treatment SummaryDexchlorpheniramine is a stronger form of chlorpheniramine, a first-generation antihistamine. It is the single active variant of the original form and is more effective at treating allergies and hay fever symptoms.
Dexchlorpheniramine Maleateis the brand name
Chlorpheniramine Maleate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dexchlorpheniramine Maleate
Dexchlorpheniramine maleate
1984
4
Approved as Treatment by the FDA
Dexchlorpheniramine maleate, also known as Dexchlorpheniramine Maleate, is approved by the FDA for 7 uses which include Allergic Conjunctivitis (AC) and Allergic Reaction .Allergic Conjunctivitis (AC)
Helps manage Allergic Conjunctivitis (AC)
Allergic Reaction
Vasomotor Rhinitis
Helps manage Vasomotor Rhinitis
Angioedema
Helps manage Angioedema
Catarrh
Hives
Helps manage Urticaria
Dermographism
Helps manage Dermographism
Effectiveness
How Chlorpheniramine Maleate Affects PatientsDuring allergic reactions, an allergen triggers the release of histamine from cells like mast cells and basophils, which can cause a variety of symptoms like itching, flushing, headaches, and breathing problems. Dexchlorpheniramine is a drug that blocks histamine from attaching to receptors in the body, providing temporary relief from hay fever and other allergy symptoms like sneezing, itchy eyes, and a runny nose.
How Chlorpheniramine Maleate works in the bodyDexchlorpheniramine works by blocking the effect of histamine in certain parts of the body, including the stomach, blood vessels and lungs. It does this by competing with histamine for certain receptor sites. Dexchlorpheniramine is more effective than other forms of chlorpheniramine because it is twice as strong.
When to interrupt dosage
The advocated dosage of Chlorpheniramine Maleate is contingent upon the diagnosed condition, such as Allergic Conjunctivitis (AC), Angioedema and Hay Fever. The quantity of dosage may vary, in accordance with the delivery technique featured in the table below.Condition
Dosage
Administration
Angioedema
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Allergic Reaction
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Catarrh
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Allergic Conjunctivitis (AC)
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Dermographism
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Hives
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Vasomotor Rhinitis
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Warnings
There are 20 known major drug interactions with Chlorpheniramine Maleate.Common Chlorpheniramine Maleate Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Dexchlorpheniramine maleate.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dexchlorpheniramine maleate.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Artemether.
Chlorpheniramine Maleate Toxicity & Overdose RiskDecreased activity in the brain and spinal cord.
Chlorpheniramine Maleate Novel Uses: Which Conditions Have a Clinical Trial Featuring Chlorpheniramine Maleate?
150 active clinical trials are being conducted to assess the utility of Chlorpheniramine Maleate in relieving Allergy, Dermographism and Catarrh Symptoms.Condition
Clinical Trials
Trial Phases
Angioedema
14 Actively Recruiting
Phase 2, Phase 3, Phase 1
Hives
19 Actively Recruiting
Early Phase 1, Phase 3, Phase 4, Phase 2, Phase 1
Allergic Reaction
3 Actively Recruiting
Not Applicable, Phase 4
Vasomotor Rhinitis
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Dermographism
0 Actively Recruiting
Catarrh
2 Actively Recruiting
Phase 2, Not Applicable
Patient Q&A Section about chlorpheniramine maleate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Does chlorpheniramine maleate 2 mg make you sleepy?
"Chlorphenamine is known to have drowsy effects, while non-drowsy antihistamines such as cetirizine, fexofenadine, and loratadine are less likely to cause drowsiness."
Answered by AI
What is chlorpheniramine maleate used for?
"Chlorpheniramine is a medication that helps to relieve symptoms such as red, itchy, watery eyes; sneezing; an itchy nose or throat; and a runny nose. These symptoms are often caused by allergies, hay fever, or the common cold. Chlorpheniramine can help control the symptoms of a cold or allergies but will not treat the underlying cause of the symptoms or speed up the recovery process."
Answered by AI