Promethazine Dm

Anaphylaxis, Catarrh, Acute Bronchitis + 18 more
Treatment
6 FDA approvals
20 Active Studies for Promethazine Dm

What is Promethazine Dm

PromethazineThe Generic name of this drug
Treatment SummaryDextromethorphan is a medication used to reduce coughing. It is a derivative of codeine but does not have the same effects on opioid receptors as other opioids. Dextromethorphan was approved by the FDA in 1957 and is sometimes abused as a recreational drug.
Phenerganis the brand name
image of different drug pills on a surface
Promethazine Dm Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Phenergan
Promethazine
1951
473

Approved as Treatment by the FDA

Promethazine, otherwise called Phenergan, is approved by the FDA for 6 uses such as Nasal Congestion and Acute Bronchitis .
Nasal Congestion
Used to treat Nasal Congestion in combination with Phenylephrine
Acute Bronchitis
Used to treat Cough in combination with Dextromethorphan
Hypersensitivity
Used to treat Allergic Reaction in combination with Codeine
Anaphylaxis
Catarrh
Used to treat Common Cold in combination with Codeine
upper respiratory symptoms
Used to treat upper respiratory symptoms in combination with Codeine

Effectiveness

How Promethazine Dm Affects PatientsDextromethorphan is used together with other medicines to treat coughing and pseudobulbar affect. It is important to be careful with this drug, as taking too much can cause intoxication. The effects of dextromethorphan generally last for a moderate amount of time. Patients should be warned about the risk of taking too much of this medication.
How Promethazine Dm works in the bodyDextromethorphan works by activating and blocking certain receptors in the body. It activates NMDA and sigma-1 receptors, as well as blocking α3/β4 nicotinic receptors. Although it is not fully understood, this action is thought to have a beneficial effect on the body.

When to interrupt dosage

The portion of Promethazine Dm is relative to the determined condition, such as Coughing, Fever and Antisepsis. The amount of dosage fluctuates, in line with the method of delivery listed in the table below.
Condition
Dosage
Administration
Hypersensitivity
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Allergic urticaria
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Sedative therapy
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Allergic Conjunctivitis (AC)
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Postoperative Pain
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
upper respiratory symptoms
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Analgesics
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Hay Fever
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Coughing
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Nasal Congestion
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Motion Sickness
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Acute Bronchitis
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Nausea
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Dermographism
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
perioperative nausea and vomiting
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Airsickness
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Rhinitis, Vasomotor
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Anaphylaxis
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Hypersensitivity
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical
Catarrh
, 12.5 mg, 25.0 mg, 50.0 mg, 6.25 mg/mL, 25.0 mg/mL, 50.0 mg/mL, 0.25 mg, 0.5 mg/mL, 1.0 mg/mL, 0.625 mg/mL, 6.5 mg/mL, 10.0 mg, 2.0 %, 10.0 mg/mL, 28.2 mg/mL, 3.125 mg/mL
Oral, Tablet - Oral, Tablet, , Syrup - Oral, Syrup, Injection, solution - Intramuscular; Intravenous, Injection, solution, Intramuscular; Intravenous, Rectal, Suppository - Rectal, Suppository, Injection, Injection - Intramuscular; Intravenous, Intramuscular, Injection - Intramuscular, Liquid, Solution, Solution - Oral, Capsule, Capsule - Oral, Injection, solution - Intramuscular, Intravenous, Injection, solution - Intravenous, Liquid - Intramuscular; Intravenous, Solution - Intramuscular; Intravenous, Cream, Cream - Topical, Liquid - Oral, Topical

Warnings

Promethazine Dm has one contraindication and should not be utilized if you experience any of the circumstances listed in the following table.Promethazine Dm Contraindications
Condition
Risk Level
Notes
subcutaneous route of administration
Do Not Combine
Asthma
Do Not Combine
Pulse Frequency
Do Not Combine
intra-arterial route of administration
Do Not Combine
Coma
Do Not Combine
lower respiratory tract symptoms
Do Not Combine
There are 20 known major drug interactions with Promethazine Dm.
Common Promethazine Dm Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Promethazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Promethazine is combined with Aclidinium.
Amisulpride
Major
Promethazine may increase the antipsychotic activities of Amisulpride.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Promethazine.
Azelastine
Major
Promethazine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Promethazine Dm Toxicity & Overdose RiskAn overdose of dextromethorphan may cause nausea, vomiting, loss of consciousness, slowed breathing, seizures, rapid heartbeat, confusion, hallucinations, unsteadiness, jerky eye movements, changes in reflexes, and serotonin syndrome. Treatment for overdose includes providing supportive care and symptom relief.

Promethazine Dm Novel Uses: Which Conditions Have a Clinical Trial Featuring Promethazine Dm?

134 active studies are underway to assess the potential of Promethazine Dm in providing relief from Influenza, Pseudobulbar Affect (PBA) and Coughing.
Condition
Clinical Trials
Trial Phases
Anaphylaxis
3 Actively Recruiting
Phase 1, Phase 2
Rhinitis, Vasomotor
0 Actively Recruiting
Motion Sickness
0 Actively Recruiting
Analgesics
2 Actively Recruiting
Phase 4
Catarrh
0 Actively Recruiting
Nausea
0 Actively Recruiting
Dermographism
0 Actively Recruiting
Acute Bronchitis
7 Actively Recruiting
Phase 4, Not Applicable, Phase 3, Early Phase 1
upper respiratory symptoms
0 Actively Recruiting
Postoperative Pain
19 Actively Recruiting
Phase 4, Phase 2, Phase 1, Phase 3, Not Applicable
Allergic urticaria
0 Actively Recruiting
perioperative nausea and vomiting
0 Actively Recruiting
Sedative therapy
0 Actively Recruiting
Pain management
0 Actively Recruiting
Nasal Congestion
0 Actively Recruiting
Hypersensitivity
1 Actively Recruiting
Phase 4
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Hay Fever
0 Actively Recruiting
Hypersensitivity
0 Actively Recruiting
Airsickness
2 Actively Recruiting
Not Applicable, Phase 3

Promethazine Dm Reviews: What are patients saying about Promethazine Dm?

5Patient Review
5/1/2021
Promethazine Dm for Cough
This treatment was very effective for my bronchitis.
5Patient Review
4/9/2022
Promethazine Dm for Cold Symptoms
This is the only treatment that has worked for me. I was sick for three weeks with upper respiratory problems, and the last doctor I saw at MD360 recommended this. I have finally had three full nights of sleep and feeling much better!
5Patient Review
6/29/2022
Promethazine Dm for Cough
This treatment is highly effective for treating coughs related to Covid-19.
4.7Patient Review
10/28/2022
Promethazine Dm for Cold Symptoms
This medication was very effective at helping me fight the flu. I would wake up drenched in sweat, but it meant that the fever had broken and I could finally get some sleep. I took another dose that night and had a similar experience.
4.3Patient Review
12/28/2021
Promethazine Dm for Cough
This treatment has helped me immensely with my cough. I was really struggling before, to the point where I didn't want to leave my house or see anyone. The promethazine-DM has made a huge difference and I'm now only coughing 10% of the time. However, I have experienced some weird dreams while taking it. Other than that, though, it's been great!
4.3Patient Review
3/18/2020
Promethazine Dm for Cough
I didn't find this to be helpful for my cough at all. If anything, I think it made it worse.
4Patient Review
1/14/2022
Promethazine Dm for Cough
I've been taking this for years and it's really helped me sleep. I'm a little frustrated that I wasn't prescribed the Prometh VC version, which has codeine in it, but overall this treatment has been great.
2.3Patient Review
11/13/2019
Promethazine Dm for Cough
Unfortunately, this medicine didn't work for me at all. In fact, it made things worse as I coughed for five minutes every time I took it.
2.3Patient Review
4/19/2019
Promethazine Dm for Cough
This medicine was prescribed to me for my cough, but it only made things worse. Not only did I not sleep at all, but my coughing fits kept me up all night.
2Patient Review
11/10/2019
Promethazine Dm for Cough
Unfortunately, this medication made me cough more. I had to sleep upright and was still waking up coughing. The headaches from all the coughing were terrible, and I was always exhausted.
2Patient Review
1/3/2020
Promethazine Dm for Cough
The article was great, but I'm still unclear on what an overdose looks like. It says to call 911, but what are the specific symptoms one should be looking for?
2Patient Review
2/18/2020
Promethazine Dm for Cough
I was extremely disappointed with this product. I originally bought it to help control my cough from the flu, but it ended up keeping me awake all night long.
2Patient Review
3/29/2019
Promethazine Dm for Cough
1.7Patient Review
5/9/2022
Promethazine Dm for Cough
Unfortunately, this medication did not help me when I needed it most. I coughed continuously and couldn't get any rest. After a few days of usage, I decided to stop taking the medicine and thankfully started feeling better soon after.
1.7Patient Review
10/22/2022
Promethazine Dm for Cough
NyQuil is better than this. Don't waste your time or money.
1Patient Review
5/9/2021
Promethazine Dm for Cough
This drug has always worked wonders for me in the past, reducing cough and sinus congestion. I take two teaspoons before bed and it allows me to sleep soundly through the night.
1Patient Review
1/7/2020
Promethazine Dm for Cough
This didn't help my cough at all. I'm going back to the doctor to ask for something else!

Patient Q&A Section about promethazine dm

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Promethazine DM?

"Promethazine DM is a combination medication that temporarily relieves symptoms related to allergies and the common cold. It is made of two ingredients, promethazine and dextromethorphan."

Answered by AI

Is promethazine a narcotic?

"Promethazine has the potential to be abused, although it is not a controlled substance. The risk of abuse is increased when it is combined with codeine, which is a combination used as a prescription medication for cough and upper respiratory symptoms accompanying allergies or a cold."

Answered by AI

Does promethazine make you sleepy?

"Promethazine is a sedating antihistamine, which means it may cause drowsiness. Non-drowsy antihistamines are less likely to have this effect."

Answered by AI

Is Promethazine DM the same as?

"Promethazine-Dm is a prescription cough syrup that helps with coughs and upper respiratory symptoms caused by colds or allergies. Promethazine is an antihistamine that eases allergy symptoms. Dextromethorphan is an opioid-like drug that stops the cough reflex in the brain's cough center."

Answered by AI

Clinical Trials for Promethazine Dm

Have you considered Promethazine Dm clinical trials? We made a collection of clinical trials featuring Promethazine Dm, we think they might fit your search criteria.Go to Trials
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Ketorolac for Infertility Treatment

18 - 37
Female
Iowa City, IA
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days later). The concern was that ketorolac might increase the risk of bleeding or reduce the chances of the embryo implanting in the uterus. This concern comes from how ketorolac works-it blocks certain chemicals in the body (like prostaglandins and thromboxane) that help with blood clotting and play a role in early pregnancy. However, a large review of past studies found no real evidence that ketorolac increases bleeding risk. In fact, ketorolac is now routinely used for pain relief in IVF cycles where embryos are frozen and not transferred right away. More recent studies from Boston and Chapel Hill have shown that ketorolac provides better pain control and does not appear to harm IVF outcomes, even when embryos are transferred fresh (within the same cycle). Despite these encouraging findings, many IVF clinics still avoid using ketorolac during fresh cycles because of the theoretical concerns. That's why we need stronger, higher-quality research. This study aims to fill that gap by conducting a double-blind randomized controlled trial to find out whether giving ketorolac through an IV after egg retrieval affects important IVF outcomes-especially the chance of implantation and live birth-in patients undergoing fresh embryo transfers. Patients who choose to join the study will randomly be placed into one of two groups. One group will get ketorolac (a pain medicine) after an IVF egg retrieval. The other group will not get ketorolac after egg retrieval. Everything else in their IVF care will stay the same as it normally would. Primary outcome will be implantation rate following fresh embryo transfers in patients receiving ketorolac (30mg IV) vs no ketorolac for post-retrieval analgesia. Secondary outcomes will include pain scale, narcotics required, time to discharge, need for evaluation w/in 24 hours for pain/bleeding, clinical pregnancy rates, miscarriage rates, and live birth rates following fresh embryo transfers in patients receiving ketorolac vs no ketorolac for post-retrieval analgesia.
Phase 4
Recruiting
UI Health Care Center for Advanced Reproductive Care
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Physical Therapy for Ventral Hernia

18 - 75
All Sexes
Philadelphia, PA
The goal of this clinical trial is to evaluate the efficacy, safety, and cost-effectiveness of a tailored physical therapy (PT) intervention targeting Abdominal Core Health components in patients recovering from ventral hernia repair. The study focuses on patients aged 18-75 diagnosed with a ventral transverse hernia between 4 cm and 10 cm, scheduled for elective Ventral Hernia Repair (VHR). The main questions it aims to answer are: * Will tailored PT significantly improve abdominal core strength, biomechanical stability, and functional mobility compared to usual care at 3-months post-surgery? * Will tailored PT lead to higher patient-reported quality of life and satisfaction scores, with a lower incidence of post-operative complications such as bowel obstruction and pelvic floor dysfunction over a 1-year follow-up? * Will tailored PT result in decreased healthcare utilization, leading to overall cost savings or neutrality compared to usual care over the first year after VHR? Researchers will compare the tailored physical therapy group to a usual care group to see if the tailored intervention leads to significant improvements in clinical efficacy, patient outcomes, and cost-effectiveness. Participants will: * Be randomly assigned to either the Usual Care Group or the PT Group. * If in the Usual Care Group, receive standard post-operative instructions for 12 weeks, including guidance on binder use, safe lifting, and gradual return to activities. * If in the PT Group, receive foundational post-operative instructions for the first 2 weeks (similar to usual care). Undergo 6 structured and individualized PT sessions over 10 weeks if in the PT Group, with progression based on Oswestry Disability Index (ODI) and Pelvic Floor Distress Inventory-20 (PFDI-20) scores, including Symptom Modulation, Movement Control, Functional Optimization, or Impairment-Based interventions. Participants undergo data collection at 2 weeks, 12 weeks, and 1 year post-operation, including imaging, functional mobility tests, pain scales, patient-reported outcomes, physical measurements, and tracking of complications and healthcare utilization. Participate in semi-structured interviews after the 12-week assessment to provide qualitative insights into their experiences and perceived barriers/facilitators.
Waitlist Available
Has No Placebo
Thomas Jefferson UniversityChristopher Keating
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Temporo-masseteric Nerve Block for Postoperative Pain

18+
All Sexes
Newark, NJ
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain, improve mouth opening and minimize pain medication consumption. 80 participants undergoing lower third molar removal under sedation will be enrolled. Those who develop significant jaw muscle pain on the following day will be randomized to receive either the TMNB injection or a placebo. Daily ecological momentary assessments (EMAs) will be collected reflecting elements of patient experience for all participants. On Day 8, participants return for an end-of-study evaluation and return their unused pain medications. Up to 40 participants who are randomized to receive TMNB/placebo will be recruited to participate in a qualitative interview regarding their experience.
Phase 2
Waitlist Available
Rutgers School of Dental Medicine
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Omeprazole + Lifestyle Therapy for Laryngopharyngeal Reflux

18 - 89
All Sexes
San Deigo, CA
The goal of this clinical trial is to learn if a mechanism guided strategy that utilizes a multidisciplinary approach to treat adults patients (age 18-89) with chronic throat symptoms who are undergoing clinical evaluation for laryngopharyngeal reflux (LPR) is more effective than the usual care strategy with proton pump inhibitor (PPI) therapy used in gastroenterology for these patients. The main question it aims to answer is: Will a greater proportion of the mechanism guided strategy participants achieve symptom response in comparison to the usual care strategy participants? If there is a comparison group: Researchers will compare the mechanism guided strategy to usual care strategy to see if treatment response differs between the groups. Participants will be be asked to do the following: * participate in an 8-week blinded study phase where they will be randomized to either 1) Mechanism Guided Strategy or 2) Usual Care Strategy * take an oral capsule daily (omeprazole 40mg or placebo) * come to 3 in-person visits at UC San Diego Health for an intervention visit with a study provider * consider incorporating recommended lifestyle modifications * complete weekly surveys
Phase 4
Recruiting
University of California San DiegoRena Yadlapati, MD
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