Kemadrin

Parkinsonism, MPTP Poisoning
Treatment
3 Active Studies for Kemadrin

What is Kemadrin

ProcyclidineThe Generic name of this drug
Treatment SummaryBenztropine is a drug that is used to treat muscle stiffness and shaking caused by certain medications. It works by blocking signals from a certain type of nerve receptor that helps control muscle movement. It can also cross the blood-brain barrier, making it useful for treating Parkinson's disease.
Kemadrinis the brand name
Kemadrin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Kemadrin
Procyclidine
1955
1

Effectiveness

How Kemadrin Affects PatientsProcyclidine works by blocking signals from the brain to certain muscles, which helps to reduce spasms. It works by blocking certain chemical receptors in the brain (M1, M2, and M4). It is used to reduce the symptoms of Parkinson's disease and to treat movement issues caused by certain psychiatric medications.
How Kemadrin works in the bodyWe don't know exactly how Procyclidine works, but it is believed to help balance nerve signaling in the brain by blocking certain types of signals. This helps relax certain muscles and reduce saliva production. It is similar to atropine in its effects.

When to interrupt dosage

The measure of Kemadrin is contingent upon the diagnosed condition. The degree of dosage is dependent on the technique of application (e.g. Oral or Tablet) specified in the table below.
Condition
Dosage
Administration
Parkinsonism
, 2.5 mg, 5.0 mg, 2.5 mg/mL
, Oral, Elixir, Elixir - Oral, Tablet, Tablet - Oral
MPTP Poisoning
, 2.5 mg, 5.0 mg, 2.5 mg/mL
, Oral, Elixir, Elixir - Oral, Tablet, Tablet - Oral

Warnings

There are 20 known major drug interactions with Kemadrin.
Common Kemadrin Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Procyclidine is combined with Aclidinium.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Procyclidine is combined with Cimetropium.
Eluxadoline
Major
The risk or severity of constipation can be increased when Procyclidine is combined with Eluxadoline.
Glycopyrronium
Major
The risk or severity of adverse effects can be increased when Procyclidine is combined with Glycopyrronium.
Ipratropium
Major
The risk or severity of adverse effects can be increased when Procyclidine is combined with Ipratropium.
Kemadrin Toxicity & Overdose RiskThe toxic dose of this drug in mice when administered intravenously is 60mg/kg.
image of a doctor in a lab doing drug, clinical research

Kemadrin Novel Uses: Which Conditions Have a Clinical Trial Featuring Kemadrin?

Two ongoing studies are examining the potential of Kemadrin to provide relief from MPTP Poisoning.
Condition
Clinical Trials
Trial Phases
MPTP Poisoning
0 Actively Recruiting
Parkinsonism
3 Actively Recruiting
Phase 4

Kemadrin Reviews: What are patients saying about Kemadrin?

4Patient Review
7/12/2008
Kemadrin for Parkinson's Disease
I've been managing my Parkinson's with Kemadrin for many years now. The increased dosage has helped me control the tremors, and I definitely notice when I miss a dose. The constipation is unpleasant but manageable. All things considered, this treatment is preferable to living with uncontrolled movement.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about kemadrin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the side effects of kemadrin?

"You may experience drowsiness, dizziness, constipation, flushing, nausea, nervousness, blurred vision, or dry mouth when taking this medication. These side effects typically go away as your body adjusts to the medicine. If any of these side effects persist or worsen, call your doctor or pharmacist."

Answered by AI

What is procyclidine medicine used for?

"Procyclidine is a drug used to treat symptoms of Parkinson's disease or involuntary movements caused by the side effects of certain psychiatric drugs (antipsychotics such as chlorpromazine/haloperidol)."

Answered by AI

What is kemadrin used for?

"Kemadrin can be used to help with the symptoms of Parkinson's disease, such as muscle stiffness, paralysis, and tremors. It can also help with problems with talking, writing, and walking."

Answered by AI

Clinical Trials for Kemadrin