BOOST-OA for Osteoarthritis
(BOOST-OA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to help Veterans with knee osteoarthritis maintain their home exercise routines during and after physical therapy. It tests a new approach called BOOST-OA, which includes special tools and health coaching to support exercise habits. Participants will either continue with regular physical therapy or receive additional support through BOOST-OA, involving ongoing coaching after therapy ends. Veterans with knee osteoarthritis, knee pain for at least three months, and difficulty walking or climbing stairs may be eligible to participate. As an unphased trial, this study offers Veterans the opportunity to explore innovative support methods to enhance their exercise routines and improve their quality of life.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.
What prior data suggests that the BOOST-OA intervention is safe for Veterans with knee osteoarthritis?
Research has shown that app-based programs for osteoarthritis (OA) are generally safe. One study found these programs effective and safe for OA patients, suggesting that the BOOST-OA program, which focuses on behavior changes, could be well-tolerated by participants.
In studies related to exercise, only a few cases reported safety issues. However, no major safety concerns emerged compared to other treatments, indicating that the exercise components of BOOST-OA are likely safe for participants.
Overall, the evidence suggests that BOOST-OA should be a safe option for those joining the trial.12345Why are researchers excited about this trial?
Researchers are excited about BOOST-OA for osteoarthritis because it combines traditional physical therapy (PT) with an innovative behavioral approach. Unlike standard PT, which typically focuses only on exercises during sessions, BOOST-OA adds components aimed at initiating and maintaining healthy behaviors beyond the clinic. This includes personalized support from a health coach via phone or video calls, reinforcing exercise habits and encouraging regular physical activity over a full year. These elements are designed to sustain improvements and potentially enhance long-term outcomes for osteoarthritis patients.
What evidence suggests that BOOST-OA is effective for improving adherence to home exercise in knee osteoarthritis?
Research has shown that exercise and follow-up sessions can improve knee osteoarthritis (OA). Studies have found that strengthening exercises and aerobic activities lessen pain and enhance physical function for individuals with mild to moderate knee OA. This trial will compare two approaches: the BOOST-OA program and usual physical therapy care. BOOST-OA includes ongoing support and coaching, aiming to maintain improvements by focusing on both exercise and healthy habits. By encouraging adherence to beneficial exercise routines, BOOST-OA may lead to better movement and reduced pain.678910
Who Is on the Research Team?
Kelli Dominick Allen, PhD
Principal Investigator
Durham VA Medical Center, Durham, NC
Are You a Good Fit for This Trial?
This trial is for Veterans with knee osteoarthritis who are receiving physical therapy. Participants should be willing to adhere to a home exercise program and participate in health coaching calls post-therapy. Specific eligibility criteria details were not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Behavior Initiation
Participants receive tools and activities to address outcome expectations, action self-efficacy, goal-setting, and monitoring during PT visits
Behavior Maintenance
Participants receive health coaching calls addressing satisfaction with outcomes, relapse prevention planning, and independent monitoring
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- BOOST-OA
Trial Overview
The study tests 'BOOST-OA', an intervention aiming to improve exercise adherence among Veterans with knee OA. It includes tools and activities during PT, followed by health coaching calls for nine months after PT ends, focusing on goal-setting, monitoring, and relapse prevention.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
BOOST-OA includes components that are integrated into PT visits (concurrent), focused on behavior initiation, as well as components that occur after PT visits have ended (sequential), focused on behavior maintenance. Concurrent components will be delivered in conjunction with usual care PT visits. Clinicians must provide enrolled Veterans with at least 4 PT visits, spaced at least weekly. PT visits must be also completed within 3 months. Sequential components will be delivered by a health coach via phone or video. Health coach sessions will be conducted every other week for the first 2 months (months 4-5), monthly for an additional 3 months (months 6- 8), and every other month for the last 4 months (months 9-12; 9 total contacts). Calls will address strengthening and stretching exercises (≥3 times per week), as well as overall physical activity (e.g., minutes / steps).
UC will be delivered by trained clinicians at participating sites. The study team will provide clinicians with guidance and training to standardize core aspects of PT, aligned with best practice recommendations. Clinicians must provide enrolled Veterans with at least 4 PT visits, spaced at least weekly so that Veterans can practice home exercise and receive guidance in exercise progression. All PT visits must be completed within 3 months.
Find a Clinic Near You
Who Is Running the Clinical Trial?
VA Office of Research and Development
Lead Sponsor
Citations
Exercise, Manual Therapy, and Booster Sessions in Knee ...
Conclusions: Spacing exercise-based physical therapy sessions over 12 months using periodic booster sessions was less costly and more effective ...
Osteoarthritis Year In Review 2024: Rehabilitation and ...
An RCT in people with hand OA found that a home exercise program did not improve muscle strength, range of motion, pain, or function in 190 participants.
Effectiveness of exercise for osteoarthritis of the knee
Muscle strengthening and aerobic exercises are effective in reducing pain and improving physical function in patients with mild to moderate OA of the knee.
Exercise, Manual Therapy, and Booster Sessions in Knee ...
Spacing exercise-based physical therapy sessions over 12 months using periodic booster sessions was less costly and more effective over 2 years than strategies ...
The Better Management of Patients with Osteoarthritis Program
This was an observational registry-based study evaluating changes in outcome variables in patients following BOA program, including patients ...
The osteoarthritis prevention study (TOPS) - PMC
Osteoarthritis (OA), the leading cause of disability among adults, has no cure and is associated with significant comorbidities.
The Effect and Safety of App-Based Interventions for ...
This study showed that app-based interventions were safe and effective for patients with OA, which might provide a cost-effective option, ...
Osteoarthritis year in review 2024: Epidemiology and therapy
The global age-standardized rate of years lived with disability (YLDs) due to OA was 255.0 YLDs (95% UI 119.7–557.2) per 100,000 in 2020, marking a 9.5% (8.6– ...
systematic review and network meta-analysis
The safety outcome was reported in a small proportion of studies (40 studies, 18%), and no clear differences were observed between exercise ...
Global, regional, and national burden of osteoarthritis ...
Compared with 2020, cases of osteoarthritis are projected to increase 74·9% (59·4–89·9) for knee, 48·6% (35·9–67·1) for hand, 78·6% (57·7–105·3) for hip, and 95 ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.