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What is Dexchlorpheniramine Maleate
Dexchlorpheniramine maleateThe Generic name of this drug
Treatment SummaryDexchlorpheniramine is an antihistamine medication used to treat allergic reactions. It is more powerful than regular chlorpheniramine, since it contains only the active form of the drug.
Dexchlorpheniramine Maleateis the brand name
Dexchlorpheniramine Maleate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dexchlorpheniramine Maleate
Dexchlorpheniramine maleate
1984
4
Approved as Treatment by the FDA
Dexchlorpheniramine maleate, also known as Dexchlorpheniramine Maleate, is approved by the FDA for 7 uses which include Allergic Conjunctivitis (AC) and Allergic Reaction .Allergic Conjunctivitis (AC)
Helps manage Allergic Conjunctivitis (AC)
Allergic Reaction
Vasomotor Rhinitis
Helps manage Vasomotor Rhinitis
Angioedema
Helps manage Angioedema
Catarrh
Hives
Helps manage Urticaria
Dermographism
Helps manage Dermographism
Effectiveness
How Dexchlorpheniramine Maleate Affects PatientsAllergic reactions occur when an allergen (a substance that causes an allergic reaction) binds to IgE antibodies on mast cells and basophils. This causes the release of histamine, a chemical which can cause a range of symptoms like itching, redness, low blood pressure, headaches, and difficulty breathing. Dexchlorpheniramine is a medicine that helps block histamine from binding to cells and relieves symptoms of allergies such as hay fever, sneezing, itchy eyes, and a runny nose.
How Dexchlorpheniramine Maleate works in the bodyDexchlorpheniramine works by blocking the histamine receptors on cells responsible for digestion, blood flow and breathing. This drug is more effective than other forms of chlorpheniramine, as it is twice as active.
When to interrupt dosage
The suggested measure of Dexchlorpheniramine Maleate is contingent upon the determined state, such as Allergic Conjunctivitis (AC), Angioedema and Hay Fever. The quantity of dosage fluctuates, depending on the application technique specified in the table below.Condition
Dosage
Administration
Angioedema
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Allergic Reaction
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Catarrh
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Allergic Conjunctivitis (AC)
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Dermographism
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Hives
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Vasomotor Rhinitis
, 2.0 mg, 2.0 mg/mL, 0.5 mg/mL, 1.0 mg/mL, 6.0 mg, 1.0 mg, 3.0 mg
, Oral, Tablet, coated, Tablet, coated - Oral, Liquid, Liquid - Oral, Solution / drops, Solution / drops - Oral, Solution, Solution - Oral, Tablet, multilayer, Tablet, multilayer - Oral, Syrup, Syrup - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral
Warnings
There are 20 known major drug interactions with Dexchlorpheniramine Maleate.Common Dexchlorpheniramine Maleate Drug Interactions
Drug Name
Risk Level
Description
Amitriptyline
Major
The metabolism of Amitriptyline can be decreased when combined with Dexchlorpheniramine maleate.
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Dexchlorpheniramine maleate.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Dexchlorpheniramine maleate is combined with Artemether.
Dexchlorpheniramine Maleate Toxicity & Overdose RiskSlowed or depressed brain activity.
Dexchlorpheniramine Maleate Novel Uses: Which Conditions Have a Clinical Trial Featuring Dexchlorpheniramine Maleate?
150 active clinical trials are currently assessing the potential of Dexchlorpheniramine Maleate to provide relief from Allergy, Dermographism and Catarrhal Symptoms.Condition
Clinical Trials
Trial Phases
Angioedema
14 Actively Recruiting
Phase 2, Phase 3, Phase 1
Hives
19 Actively Recruiting
Early Phase 1, Phase 3, Phase 4, Phase 2, Phase 1
Allergic Reaction
3 Actively Recruiting
Not Applicable, Phase 4
Vasomotor Rhinitis
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Dermographism
0 Actively Recruiting
Catarrh
2 Actively Recruiting
Phase 2, Not Applicable
Dexchlorpheniramine Maleate Reviews: What are patients saying about Dexchlorpheniramine Maleate?
4.7Patient Review
3/11/2014 I was struggling with a skin issue that was only getting worse with my previous doctor's treatment. I decided to switch, and the new doctor put me on Atminic. It worked like a charm--I saw results within just three days! Plus, I didn't experience any negative side effects, which was great.
4.3Patient Review
11/2/2014 This medication was incredibly effective for me in addressing a chronic cough that I had been struggling with for some time. Nothing else on the market worked as well as this did to finally give me some relief and allow me to get a good night's sleep.
Patient Q&A Section about dexchlorpheniramine maleate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What class of drug is dexchlorpheniramine maleate?
"Dexchlorpheniramine works by blocking histamine H1 receptors. Histamine is a chemical that is released by the body during an allergic reaction. When histamine binds to histamine H1 receptors, it causes symptoms such as sneezing, itching, and increased mucus production. By blocking histamine H1 receptors, dexchlorpheniramine reduces these symptoms."
Answered by AI
Is dexchlorpheniramine maleate a steroid?
"TheBetamethasone/dexchlorpheniramine drug contains both betamethasone (a steroid) and dexchlorpheniramine maleate (an antihistamine) to treat allergic conditions. The betamethasone component works to relieve itches and inflammation while the dexchlorpheniramine maleate component helps to treat urticaria (hives)."
Answered by AI
What is dexchlorpheniramine maleate used for?
"The medication dexchlorpheniramine is used to relieve symptoms that are commonly associated with allergies, hay fever, and the cold. These symptoms can manifest as a rash, watery eyes, itchiness in the eyes, nose, throat, or skin, a cough, a runny nose, or sneezing."
Answered by AI
Does dexchlorpheniramine make you sleepy?
"While taking dexchlorpheniramine, be cautious about using alcohol as it may increase drowsiness and dizziness. If you experience these effects, avoid activities that require alertness such as operating machinery or driving."
Answered by AI