Karbinal Er

Anaphylaxis, Angioedema, Hives + 4 more

Treatment

11 FDA approvals

8 Active Studies for Karbinal Er

What is Karbinal Er

Carbinoxamine

The Generic name of this drug

Treatment Summary

Carbinoxamine is an allergy medicine that works by blocking the effects of histamine, a substance that can cause sneezing, runny nose, and other allergy symptoms. The product label for carbinoxamine has been changed to state "do not use" in children under 4 years of age because unapproved uses can cause serious health risks.

Rondamine DM

is the brand name

Karbinal Er Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Rondamine DM

Carbinoxamine

2002

21

Approved as Treatment by the FDA

Carbinoxamine, otherwise known as Rondamine DM, is approved by the FDA for 11 uses like Urticaria and Angioedema .

Urticaria

Angioedema

Vasomotor Rhinitis

Allergic Rhinitis (AR)

Hypersensitivity

dermatographism

Anaphylaxis

Allergic Conjunctivitis (AC)

Hives

Rhinitis, Vasomotor

Angioedema

Effectiveness

How Karbinal Er Affects Patients

Carbinoxamine is an antihistamine medication that helps to relieve many allergic symptoms, such as itchy eyes, sneezing, and a runny nose. It is also used to treat irritant cough, nausea, and vertigo caused by motion sickness. It can be used to reduce the effects of drugs that cause muscle spasms, and it may also help with mild cases of Parkinson's disease. Carbinoxamine works by blocking histamine from attaching to receptors in the stomach, uterus, blood vessels, and bronchial muscles, preventing it from causing inflammation and other symptoms. Compared to other antihistamines, this

How Karbinal Er works in the body

Carbinoxamine helps reduce allergy symptoms by blocking histamine from attaching to receptors in the body. This stops the negative effects of histamine. It also has an anti-muscarinic effect, which may contribute to its anti-nausea effects, though the exact mechanism is unknown.

When to interrupt dosage

The amount of Karbinal Er is contingent upon the diagnosed affliction, such as Vasomotor Rhinitis, Allergic Conjunctivitis (AC) and Allergic Reaction. The dosage can be found in the table beneath, depending on the method of delivery (e.g. Oral or Tablet - Oral).

Condition

Dosage

Administration

Anaphylaxis

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

dermatographism

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Rhinitis, Vasomotor

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Hypersensitivity

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Allergic Conjunctivitis (AC)

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Angioedema

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Hives

4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL

, Oral, Syrup, Syrup - Oral, Tablet, Tablet - Oral, Solution, Solution - Oral, Liquid - Oral, Liquid, Suspension, extended release, Suspension, extended release - Oral

Warnings

Karbinal Er has two contraindications, therefore it should not be utilized while suffering from any of the conditions shown in the following table.

Karbinal Er Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Karbinal Er.

Common Karbinal Er Drug Interactions

Drug Name

Risk Level

Description

Amiodarone

Major

The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Amiodarone.

Anagrelide

Major

The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Anagrelide.

Arsenic trioxide

Major

The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Arsenic trioxide.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Artemether.

Asenapine

Major

The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Asenapine.

image of a doctor in a lab doing drug, clinical research

Karbinal Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Karbinal Er?

43 active studies are being conducted to assess the potential of Karbinal Er to provide relief from Allergic Reaction, dermatographism and Angioedema.

Condition

Clinical Trials

Trial Phases

Hypersensitivity

1 Actively Recruiting

Phase 4

Hives

0 Actively Recruiting

dermatographism

0 Actively Recruiting

Rhinitis, Vasomotor

1 Actively Recruiting

Not Applicable

Anaphylaxis

3 Actively Recruiting

Phase 1, Phase 2

Allergic Conjunctivitis (AC)

1 Actively Recruiting

Phase 2

Angioedema

2 Actively Recruiting

Phase 4, Phase 1, Phase 2

Karbinal Er Reviews: What are patients saying about Karbinal Er?

4

Patient Review

7/27/2019

Karbinal Er for Allergic Conjunctivitis

This medicine is much more effective than anything else I've tried for my allergies.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about karbinal er

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Karbinal an antihistamine?

"Karbinal ER is a medication used to treat allergies. It is an antihistamine of the H1 type, which means it works by blocking histamine receptors. Histamine is a chemical that is released during an allergic reaction and is responsible for many of the symptoms associated with allergies, such as itching, sneezing, and watery eyes."

Answered by AI

Is Karbinal a prescription?

"Karbinal Er is a prescription medication that is used as an antihistamine to treat conditions such as allergic rhinitis, allergic conjunctivitis, skin allergies, hives, anaphylaxis, and nasal congestion. It can also be used to treat insomnia."

Answered by AI

What is Karbinal er used for?

"Carbinoxamine is an antihistamine that helps to relieve symptoms such as a rash, watery eyes, itchiness in the eyes, nose, throat, or skin, a cough, a runny nose, and sneezing. These symptoms are often associated with allergies, hay fever, and the common cold."

Answered by AI

Does Karbinal cause drowsiness?

"The following effects may occur: drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat. These effects may go away during treatment as your body adjusts to the medicine. If they continue or get worse, check with your doctor."

Answered by AI

Clinical Trials for Karbinal Er

Image of Cedars-Sinai Medical Center Otolaryngology Clinics in Los Angeles, United States.

Lavender Aromatherapy for Anxiety and Pain During Otolaryngologic Procedures

18+
All Sexes
Los Angeles, CA

The purpose of this study is to evaluate the efficacy of lavender aromatherapy in adult patients undergoing awake otolaryngologic procedures in the outpatient clinic setting. The main questions it aims to answer are: * Does lavender aromatherapy help reduce anxiety and/or pain, and improve patient comfort during awake otolaryngologic procedures in the clinic? * Do patients subjectively find aromatherapy relaxing and/or beneficial during the procedure? Researchers will compare lavender aromatherapy to placebo (an odorless liquid) to see if lavender aromatherapy helps improve patient comfort during their awake procedure Participants will: * Have their scheduled procedure performed with lavender aromatherapy or placebo during the duration of the procedure * Take a short, less than 1 minute questionnaire both before and after the procedure, describing their levels of anxiety, pain and subjective impressions of the aromatherapy

Recruiting
Paid Trial

Cedars-Sinai Medical Center Otolaryngology Clinics

Ankona Ghosh, MD

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