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What is Karbinal Er
CarbinoxamineThe Generic name of this drug
Treatment SummaryCarbinoxamine is an allergy medicine that works by blocking the effects of histamine, a substance that can cause sneezing, runny nose, and other allergy symptoms. The product label for carbinoxamine has been changed to state "do not use" in children under 4 years of age because unapproved uses can cause serious health risks.
Rondamine DMis the brand name
Karbinal Er Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rondamine DM
Carbinoxamine
2002
21
Approved as Treatment by the FDA
Carbinoxamine, otherwise known as Rondamine DM, is approved by the FDA for 7 uses like Allergic Reaction and Allergic Conjunctivitis (AC) .Allergic Reaction
Allergic Conjunctivitis (AC)
Angioedema
Anaphylaxis
Vasomotor Rhinitis
Hives
dermatographism
Effectiveness
How Karbinal Er Affects PatientsCarbinoxamine is an antihistamine medication that helps to relieve many allergic symptoms, such as itchy eyes, sneezing, and a runny nose. It is also used to treat irritant cough, nausea, and vertigo caused by motion sickness. It can be used to reduce the effects of drugs that cause muscle spasms, and it may also help with mild cases of Parkinson's disease. Carbinoxamine works by blocking histamine from attaching to receptors in the stomach, uterus, blood vessels, and bronchial muscles, preventing it from causing inflammation and other symptoms. Compared to other antihistamines, this
How Karbinal Er works in the bodyCarbinoxamine helps reduce allergy symptoms by blocking histamine from attaching to receptors in the body. This stops the negative effects of histamine. It also has an anti-muscarinic effect, which may contribute to its anti-nausea effects, though the exact mechanism is unknown.
When to interrupt dosage
The amount of Karbinal Er is contingent upon the diagnosed affliction, such as Vasomotor Rhinitis, Allergic Conjunctivitis (AC) and Allergic Reaction. The dosage can be found in the table beneath, depending on the method of delivery (e.g. Oral or Tablet - Oral).Condition
Dosage
Administration
dermatographism
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Allergic Reaction
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Allergic Conjunctivitis (AC)
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Angioedema
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Anaphylaxis
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Hives
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Vasomotor Rhinitis
4.0 mg/mL, , 4.0 mg, 0.8 mg/mL, 6.0 mg, 1.0 mg/mL, 2.0 mg/mL
, Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Solution, Solution - Oral, Suspension, extended release, Suspension, extended release - Oral, Liquid, Liquid - Oral
Warnings
Karbinal Er has two contraindications, therefore it should not be utilized while suffering from any of the conditions shown in the following table.Karbinal Er ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Common Karbinal Er Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Amiodarone.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Arsenic trioxide.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Artemether.
Asenapine
Major
The risk or severity of QTc prolongation can be increased when Carbinoxamine is combined with Asenapine.
Karbinal Er Novel Uses: Which Conditions Have a Clinical Trial Featuring Karbinal Er?
43 active studies are being conducted to assess the potential of Karbinal Er to provide relief from Allergic Reaction, dermatographism and Angioedema.Condition
Clinical Trials
Trial Phases
Anaphylaxis
3 Actively Recruiting
Phase 2, Not Applicable
dermatographism
0 Actively Recruiting
Angioedema
14 Actively Recruiting
Phase 2, Phase 3, Phase 1
Hives
19 Actively Recruiting
Early Phase 1, Phase 3, Phase 4, Phase 2, Phase 1
Allergic Reaction
3 Actively Recruiting
Not Applicable, Phase 4
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Vasomotor Rhinitis
0 Actively Recruiting
Karbinal Er Reviews: What are patients saying about Karbinal Er?
4Patient Review
7/27/2019 This medicine is much more effective than anything else I've tried for my allergies.
Patient Q&A Section about karbinal er
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Karbinal an antihistamine?
"Karbinal ER is a medication used to treat allergies. It is an antihistamine of the H1 type, which means it works by blocking histamine receptors. Histamine is a chemical that is released during an allergic reaction and is responsible for many of the symptoms associated with allergies, such as itching, sneezing, and watery eyes."
Answered by AI
Is Karbinal a prescription?
"Karbinal Er is a prescription medication that is used as an antihistamine to treat conditions such as allergic rhinitis, allergic conjunctivitis, skin allergies, hives, anaphylaxis, and nasal congestion. It can also be used to treat insomnia."
Answered by AI
What is Karbinal er used for?
"Carbinoxamine is an antihistamine that helps to relieve symptoms such as a rash, watery eyes, itchiness in the eyes, nose, throat, or skin, a cough, a runny nose, and sneezing. These symptoms are often associated with allergies, hay fever, and the common cold."
Answered by AI
Does Karbinal cause drowsiness?
"The following effects may occur: drowsiness, dizziness, headache, constipation, stomach upset, blurred vision, decreased coordination, or dry mouth/nose/throat. These effects may go away during treatment as your body adjusts to the medicine. If they continue or get worse, check with your doctor."
Answered by AI