Allegra Allergy

Chronic Urticaria, Hay Fever, antihistamine
Treatment
2 FDA approvals
2 Active Studies for Allegra Allergy

What is Allegra Allergy

FexofenadineThe Generic name of this drug
Treatment SummaryFexofenadine is an over-the-counter antihistamine medication used to treat allergies. It is more selective for the H1 receptor than older antihistamines and does not cross the blood-brain barrier, meaning it does not cause side effects like drowsiness. Fexofenadine is the main active ingredient in terfenadine and is given as a mix of two enantiomers which both have similar antihistamine effects.
Allegra D-12 Houris the brand name
image of different drug pills on a surface
Allegra Allergy Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Allegra D-12 Hour
Fexofenadine
1997
525

Approved as Treatment by the FDA

Fexofenadine, also known as Allegra D-12 Hour, is approved by the FDA for 2 uses including Hay Fever and Chronic Urticaria .
Hay Fever
Chronic Urticaria

Effectiveness

How Allegra Allergy Affects PatientsFexofenadine is a drug used to treat allergy symptoms. It works by blocking the effects of histamine, a chemical naturally produced by your body which is responsible for allergy symptoms. Fexofenadine usually lasts around 24 hours and starts working within 1-3 hours. It should not be taken with fruit juice, as this can reduce its effectiveness.
How Allegra Allergy works in the bodyFexofenadine is used to treat allergies. It works by preventing the activation of a receptor called H1 histamine, which triggers the body's allergic response. Fexofenadine has a strong and specific affinity for this receptor and won't cause any side effects in the central nervous system. It stabilizes the inactive form of the receptor, keeping it from activating and causing the body's allergic response.

When to interrupt dosage

The measure of Allegra Allergy is contingent upon the diagnosed condition, including Hay Fever, Hay Fever and antihistamine. The amount of dosage fluctuates in accordance with the method of delivery featured in the following table.
Condition
Dosage
Administration
Hay Fever
, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Capsule, Capsule - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Capsule, coated, Capsule, coated - Oral
antihistamine
, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Capsule, Capsule - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Capsule, coated, Capsule, coated - Oral
Chronic Urticaria
, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Capsule, Capsule - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Capsule, coated, Capsule, coated - Oral

Warnings

Allegra Allergy Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Fexofenadine may interact with Pulse Frequency
There are 20 known major drug interactions with Allegra Allergy.
Common Allegra Allergy Drug Interactions
Drug Name
Risk Level
Description
Pitolisant
Major
The therapeutic efficacy of Pitolisant can be decreased when used in combination with Fexofenadine.
Abemaciclib
Moderate
The serum concentration of Abemaciclib can be increased when it is combined with Fexofenadine.
Ambrisentan
Moderate
The serum concentration of Ambrisentan can be increased when it is combined with Fexofenadine.
Apixaban
Moderate
The serum concentration of Apixaban can be increased when it is combined with Fexofenadine.
Avanafil
Moderate
The serum concentration of Avanafil can be increased when it is combined with Fexofenadine.
Allegra Allergy Toxicity & Overdose RiskMice and rats have been observed to be unharmed after taking up to 5000mg/kg of fexofenadine, which is approximately 100-200 times the recommended dose for humans. People taking up to 800mg of fexofenadine at once or 690mg twice a day for one month have not experienced any serious side effects. Signs of an overdose are likely to include dizziness, drowsiness, and dry mouth. If an overdose occurs, symptoms should be treated and monitored. Hemodialysis does not help remove fexofenadine from the blood.
image of a doctor in a lab doing drug, clinical research

Allegra Allergy Novel Uses: Which Conditions Have a Clinical Trial Featuring Allegra Allergy?

Currently, there are 7 active studies evaluating the effectiveness of Allegra Allergy as an antihistamine for Chronic Idiopathic Urticaria and Hay Fever.
Condition
Clinical Trials
Trial Phases
Chronic Urticaria
1 Actively Recruiting
Phase 4
Hay Fever
1 Actively Recruiting
Phase 3
antihistamine
0 Actively Recruiting

Allegra Allergy Reviews: What are patients saying about Allegra Allergy?

5Patient Review
10/21/2012
Allegra Allergy for Inflammation of the Nose due to an Allergy
I had really bad watery eyes a few years back and tried a bunch of different medicines with no success. Once I started taking Allegra Allergy though, it was an immediate and noticeable difference. I'm so happy that this worked for me!
5Patient Review
11/6/2022
Allegra Allergy for Inflammation of the Nose due to an Allergy
Allegra has been a life-saver for me. It's the only allergy medication that I've taken that doesn't stop working after extended use, and it helps with all of my symptoms: indoor allergies, outdoor allergies, post-nasal drip, itchiness, and sneezing.
5Patient Review
11/14/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
This treatment has helped me breathe better.
5Patient Review
11/14/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
This treatment has helped me to breathe better.
5Patient Review
11/6/2022
Allegra Allergy for Inflammation of the Nose due to an Allergy
Allegra has been a game-changer for me. It's the only allergy medication that hasn't lost its efficacy over time, and it really helps with symptoms like post-nasal drip, itchiness, and sneezing. I highly recommend it!
5Patient Review
10/21/2012
Allegra Allergy for Inflammation of the Nose due to an Allergy
I had such bad watery eyes a few years ago and tried multiple medicines with no success. Once I started taking Allegra Allergy though, I was so pleased with how well it worked!
4.3Patient Review
3/22/2012
Allegra Allergy for Inflammation of the Nose due to an Allergy
I'm content with the daily dosage
4.3Patient Review
3/22/2012
Allegra Allergy for Inflammation of the Nose due to an Allergy
I'm happy with the results I achieved by taking this once per day.
4Patient Review
9/26/2011
Allegra Allergy for Seasonal Runny Nose
I developed an inner ear infection, pink eye, and a herpe infection in my left eye within the three months of using this drug. The side effects were too much for me so I went back to Zyrtec.
4Patient Review
9/26/2011
Allegra Allergy for Seasonal Runny Nose
I used this medication for three months. In that time, I got an inner ear infection, pink eye, and a herpe infection in my left eye. I went back to using Zyrtec because the side effects were worse with Allegra.
3.7Patient Review
7/28/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
I've had much better luck with this medicine than in the past. I also appreciate that the D formula only has to be taken once a day.
3.7Patient Review
7/28/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
I've had much better results with this medicine than in the past. I also appreciate that it only needs to be taken once a day.
3.3Patient Review
10/15/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
Allegra caused me some serious sexual dysfunction problems that I wasn't expecting. Once I stopped taking the medication, it went away; however, it was definitely a frustrating experience while it lasted.
3.3Patient Review
10/15/2011
Allegra Allergy for Inflammation of the Nose due to an Allergy
One big issue I had was that this caused sexual dysfunction. I was surprised that doctors don't list this as a potential side effect, because it's pretty well known in the medical community. Stopping the medication for a few days clears up the problem though.
2.7Patient Review
9/30/2018
Allegra Allergy for Hives
My 7-year-old daughter has been taking Allegra Allergy for a little over a year. Two weeks ago, she started breaking out in hives around her thighs. We've ruled out changes to her food and laundry detergent, so we followed the advice of an allergy specialist and doubled her dosage. Unfortunately, this has only made the hives worse. We think she's experiencing a rare but serious side effect of the medication.
2.7Patient Review
5/8/2013
Allegra Allergy for Seasonal Runny Nose
This medication helped to slow the production of mucus, but I still found it going down my throat more often than I'd like.
2.7Patient Review
5/8/2013
Allegra Allergy for Seasonal Runny Nose
This medication helped to slow the production of mucus, but I still found it draining into my throat.
2.7Patient Review
9/30/2018
Allegra Allergy for Hives
My daughter has been taking Allegra for a little over a year, but in the past two weeks she's started breaking out in hives. We've ruled out any changes in her diet or laundry detergent, so we saw an allergy specialist. They told us to double her dosage, but that only made the hives worse. We think she's having a rare but serious side effect to the medication.
1Patient Review
1/7/2018
Allegra Allergy for Seasonal Runny Nose
This made me really uncomfortable and did nothing to help my allergies. Flonase has been a much better experience.
1Patient Review
1/7/2018
Allegra Allergy for Seasonal Runny Nose
This made me really anxious and I was starving all the time. Obviously, it did nothing for my allergies since I had to switch to Flonase eventually.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about allegra allergy

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between Claritin & Allegra?

"Do Allegra and Claritin have the same active ingredient?

No, Allegra and Claritin do not have the same active ingredient. Allegra contains fexofenadine hydrochloride and Claritin contains loratadine."

Answered by AI

What allergies is Allegra good for?

"Fexofenadine hydrochloride is the active ingredient in Allegra. It is used to relieve symptoms of hay fever and other upper respiratory allergies such as runny nose, sneezing, itching of nose or throat, and itchy, watery eyes. It is also used to treat hives and skin rash."

Answered by AI

Is Zyrtec the same as Allegra?

"Allegra is the better choice if you have troubles with Yeast infections.

The main difference between Allegra and Zyrtec is that Zyrtec's effects may last longer than Allegra's, but Allegra is less likely to cause drowsiness. Another difference is that drinking fruit juices can make Allegra less effective. Finally, Allegra is the better choice if you have troubles with Yeast infections."

Answered by AI

What are the side effects of Allegra allergy?

"The most common side effects of this medication include nausea, diarrhea, upset stomach, muscle or back discomfort or pain, sleepiness, drowsiness, tiredness, headache, and."

Answered by AI

Clinical Trials for Allegra Allergy