Allegra Allergy

Chronic Urticaria, Hay Fever, antihistamine

Treatment

5 FDA approvals

0 Active Studies for Allegra Allergy

Treatment for

Chronic Urticaria

What is Allegra Allergy

Fexofenadine

The Generic name of this drug

Treatment Summary

Fexofenadine is an over-the-counter antihistamine medication used to treat allergies. It is more selective for the H1 receptor than older antihistamines and does not cross the blood-brain barrier, meaning it does not cause side effects like drowsiness. Fexofenadine is the main active ingredient in terfenadine and is given as a mix of two enantiomers which both have similar antihistamine effects.

Allegra D-12 Hour

is the brand name

image of different drug pills on a surface

Allegra Allergy Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Allegra D-12 Hour

Fexofenadine

1997

525

Approved as Treatment by the FDA

Fexofenadine, also known as Allegra D-12 Hour, is approved by the FDA for 5 uses including Seasonal Allergic Rhinitis and Chronic Idiopathic Urticaria .

Seasonal Allergic Rhinitis

Chronic Idiopathic Urticaria

Allergic Rhinitis (AR)

Hay Fever

Chronic Urticaria

Effectiveness

How Allegra Allergy Affects Patients

Fexofenadine is a drug used to treat allergy symptoms. It works by blocking the effects of histamine, a chemical naturally produced by your body which is responsible for allergy symptoms. Fexofenadine usually lasts around 24 hours and starts working within 1-3 hours. It should not be taken with fruit juice, as this can reduce its effectiveness.

How Allegra Allergy works in the body

Fexofenadine is used to treat allergies. It works by preventing the activation of a receptor called H1 histamine, which triggers the body's allergic response. Fexofenadine has a strong and specific affinity for this receptor and won't cause any side effects in the central nervous system. It stabilizes the inactive form of the receptor, keeping it from activating and causing the body's allergic response.

When to interrupt dosage

The measure of Allegra Allergy is contingent upon the diagnosed condition, including Hay Fever, Hay Fever and antihistamine. The amount of dosage fluctuates in accordance with the method of delivery featured in the following table.

Condition

Dosage

Administration

Chronic Urticaria

, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg

Tablet, extended release - Oral, Oral, Tablet, extended release, , Tablet, film coated, Suspension, Suspension - Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, coated, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Capsule - Oral, Capsule, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Capsule, coated, Capsule, coated - Oral

Hay Fever

, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg

antihistamine

, 60.0 mg, 180.0 mg, 6.0 mg/mL, 30.0 mg/mL, 30.0 mg, 120.0 mg

Warnings

Allegra Allergy Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Fexofenadine may interact with Pulse Frequency

There are 20 known major drug interactions with Allegra Allergy.

Common Allegra Allergy Drug Interactions

Drug Name

Risk Level

Description

Pitolisant

Major

The therapeutic efficacy of Pitolisant can be decreased when used in combination with Fexofenadine.

Abemaciclib

Moderate

The serum concentration of Abemaciclib can be increased when it is combined with Fexofenadine.

Ambrisentan

Moderate

The serum concentration of Ambrisentan can be increased when it is combined with Fexofenadine.

Apixaban

Moderate

The serum concentration of Apixaban can be increased when it is combined with Fexofenadine.

Avanafil

Moderate

The serum concentration of Avanafil can be increased when it is combined with Fexofenadine.

Allegra Allergy Toxicity & Overdose Risk

Mice and rats have been observed to be unharmed after taking up to 5000mg/kg of fexofenadine, which is approximately 100-200 times the recommended dose for humans. People taking up to 800mg of fexofenadine at once or 690mg twice a day for one month have not experienced any serious side effects. Signs of an overdose are likely to include dizziness, drowsiness, and dry mouth. If an overdose occurs, symptoms should be treated and monitored. Hemodialysis does not help remove fexofenadine from the blood.

image of a doctor in a lab doing drug, clinical research

Allegra Allergy Novel Uses: Which Conditions Have a Clinical Trial Featuring Allegra Allergy?

Currently, there are 7 active studies evaluating the effectiveness of Allegra Allergy as an antihistamine for Chronic Idiopathic Urticaria and Hay Fever.

Condition

Clinical Trials

Trial Phases

Hay Fever

0 Actively Recruiting

Chronic Urticaria

0 Actively Recruiting

antihistamine

0 Actively Recruiting

Allegra Allergy Reviews: What are patients saying about Allegra Allergy?

Patient Review

10/21/2012

Allegra Allergy for Inflammation of the Nose due to an Allergy

I had really bad watery eyes a few years back and tried a bunch of different medicines with no success. Once I started taking Allegra Allergy though, it was an immediate and noticeable difference. I'm so happy that this worked for me!

Patient Review

11/6/2022

Allegra Allergy for Inflammation of the Nose due to an Allergy

Allegra has been a life-saver for me. It's the only allergy medication that I've taken that doesn't stop working after extended use, and it helps with all of my symptoms: indoor allergies, outdoor allergies, post-nasal drip, itchiness, and sneezing.

Patient Review

11/14/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

This treatment has helped me breathe better.

Patient Review

11/14/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

This treatment has helped me to breathe better.

Patient Review

11/6/2022

Allegra Allergy for Inflammation of the Nose due to an Allergy

Allegra has been a game-changer for me. It's the only allergy medication that hasn't lost its efficacy over time, and it really helps with symptoms like post-nasal drip, itchiness, and sneezing. I highly recommend it!

Patient Review

10/21/2012

Allegra Allergy for Inflammation of the Nose due to an Allergy

I had such bad watery eyes a few years ago and tried multiple medicines with no success. Once I started taking Allegra Allergy though, I was so pleased with how well it worked!

4.3

Patient Review

3/22/2012

Allegra Allergy for Inflammation of the Nose due to an Allergy

I'm content with the daily dosage

4.3

Patient Review

3/22/2012

Allegra Allergy for Inflammation of the Nose due to an Allergy

I'm happy with the results I achieved by taking this once per day.

Patient Review

9/26/2011

Allegra Allergy for Seasonal Runny Nose

I developed an inner ear infection, pink eye, and a herpe infection in my left eye within the three months of using this drug. The side effects were too much for me so I went back to Zyrtec.

Patient Review

9/26/2011

Allegra Allergy for Seasonal Runny Nose

I used this medication for three months. In that time, I got an inner ear infection, pink eye, and a herpe infection in my left eye. I went back to using Zyrtec because the side effects were worse with Allegra.

3.7

Patient Review

7/28/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

I've had much better luck with this medicine than in the past. I also appreciate that the D formula only has to be taken once a day.

3.7

Patient Review

7/28/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

I've had much better results with this medicine than in the past. I also appreciate that it only needs to be taken once a day.

3.3

Patient Review

10/15/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

Allegra caused me some serious sexual dysfunction problems that I wasn't expecting. Once I stopped taking the medication, it went away; however, it was definitely a frustrating experience while it lasted.

3.3

Patient Review

10/15/2011

Allegra Allergy for Inflammation of the Nose due to an Allergy

One big issue I had was that this caused sexual dysfunction. I was surprised that doctors don't list this as a potential side effect, because it's pretty well known in the medical community. Stopping the medication for a few days clears up the problem though.

2.7

Patient Review

9/30/2018

Allegra Allergy for Hives

My 7-year-old daughter has been taking Allegra Allergy for a little over a year. Two weeks ago, she started breaking out in hives around her thighs. We've ruled out changes to her food and laundry detergent, so we followed the advice of an allergy specialist and doubled her dosage. Unfortunately, this has only made the hives worse. We think she's experiencing a rare but serious side effect of the medication.

2.7

Patient Review

5/8/2013

Allegra Allergy for Seasonal Runny Nose

This medication helped to slow the production of mucus, but I still found it going down my throat more often than I'd like.

2.7

Patient Review

5/8/2013

Allegra Allergy for Seasonal Runny Nose

This medication helped to slow the production of mucus, but I still found it draining into my throat.

2.7

Patient Review

9/30/2018

Allegra Allergy for Hives

My daughter has been taking Allegra for a little over a year, but in the past two weeks she's started breaking out in hives. We've ruled out any changes in her diet or laundry detergent, so we saw an allergy specialist. They told us to double her dosage, but that only made the hives worse. We think she's having a rare but serious side effect to the medication.

Patient Review

1/7/2018

Allegra Allergy for Seasonal Runny Nose

This made me really uncomfortable and did nothing to help my allergies. Flonase has been a much better experience.

Patient Review

1/7/2018

Allegra Allergy for Seasonal Runny Nose

This made me really anxious and I was starving all the time. Obviously, it did nothing for my allergies since I had to switch to Flonase eventually.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about allegra allergy

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the difference between Claritin & Allegra?

"Do Allegra and Claritin have the same active ingredient?

No, Allegra and Claritin do not have the same active ingredient. Allegra contains fexofenadine hydrochloride and Claritin contains loratadine."

Answered by AI

What allergies is Allegra good for?

"Fexofenadine hydrochloride is the active ingredient in Allegra. It is used to relieve symptoms of hay fever and other upper respiratory allergies such as runny nose, sneezing, itching of nose or throat, and itchy, watery eyes. It is also used to treat hives and skin rash."

Answered by AI

Is Zyrtec the same as Allegra?

"Allegra is the better choice if you have troubles with Yeast infections.

The main difference between Allegra and Zyrtec is that Zyrtec's effects may last longer than Allegra's, but Allegra is less likely to cause drowsiness. Another difference is that drinking fruit juices can make Allegra less effective. Finally, Allegra is the better choice if you have troubles with Yeast infections."

Answered by AI

What are the side effects of Allegra allergy?

"The most common side effects of this medication include nausea, diarrhea, upset stomach, muscle or back discomfort or pain, sleepiness, drowsiness, tiredness, headache, and."

Answered by AI