Caffeine Citrate

Vascular Headaches, Indigestion, Toothache + 20 more

Treatment

12 FDA approvals

20 Active Studies for Caffeine Citrate

What is Caffeine Citrate

Caffeine

The Generic name of this drug

Treatment Summary

Caffeine is a drug used to treat several conditions, such as respiratory issues in premature babies, pain relief, and drowsiness. It is found naturally in coffee beans, teas, and cacao beans. It is sometimes used in cosmetic products and can be taken orally, by inhalation, or by injection. Caffeine citrate injection is approved by the FDA and is used to treat apnea of the premature newborn. It is helpful in preventing and treating apnea and bronchopulmonary dysplasia in premature infants, which can lead to asthma and early onset emphysema.

Cafergot

is the brand name

image of different drug pills on a surface

Caffeine Citrate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cafergot

Caffeine

1953

390

Approved as Treatment by the FDA

Caffeine, also called Cafergot, is approved by the FDA for 12 uses including Drug Overdose and Tension Headache .

Drug Overdose

Tension Headache

Used to treat Tension Headache in combination with Acetylsalicylic acid

central nervous system depression

Respiratory Insufficiency

Chronic Fatigue Syndrome

Vascular Headaches

Used to treat Vascular Headaches in combination with Ergotamine

Fatigue

Pain

Used to treat Pain in combination with Acetaminophen

Mental Depression

Pain

Used to treat moderate Pain in combination with Acetaminophen

Chronic Pain

Used to treat Pain in combination with Acetaminophen

Tension-Type Headache

Used to treat Tension Headache in combination with Acetylsalicylic acid

Effectiveness

How Caffeine Citrate Affects Patients

Caffeine can make people feel more alert and active, but can also lead to feeling jittery and restless. Caffeine also helps to relax certain muscles, make the heart beat faster, and can improve athletic performance. It can also increase stomach acid and help with digestion, as well as help relieve migraine and other types of headaches when combined with other medications. Lastly, caffeine acts as a mild diuretic.

How Caffeine Citrate works in the body

Caffeine affects many body systems in various ways. It can reduce drowsiness by blocking adenosine receptors in the brain, and can have a diuretic effect by increasing sodium excretion in the kidneys. In the heart, caffeine can increase heart rate and blood pressure, while also widening blood vessels. This helps to relieve migraines and headaches, which are often caused by narrowed vessels in the brain. Caffeine also has other effects on cells, but the clinical relevance of these is not well understood.

When to interrupt dosage

The quantity of Caffeine Citrate is contingent upon the diagnosed condition, including Overdose, Drug, Catarrh and Athletic Performance. The amount also changes as per the technique of delivery (e.g. Tablet or Tablet - Oral) presented in the table beneath.

Condition

Dosage

Administration

Eye

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Catarrh

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain relief

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Tension-Type Headache

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Acute Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Toothache

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain management

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Athletic Performance

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Vascular Headaches

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Indigestion

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Chronic Fatigue Syndrome

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Muscle Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Bronchopulmonary Dysplasia

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Chronic Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Migraine

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Sleepiness

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Fever

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Influenza

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Antacid therapy

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Warnings

Caffeine Citrate has one contraindication, so it should not be consumed for the conditions listed in the following table.

Caffeine Citrate Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Caffeine may interact with Pulse Frequency

There are 20 known major drug interactions with Caffeine Citrate.

Common Caffeine Citrate Drug Interactions

Drug Name

Risk Level

Description

Acenocoumarol

Major

The metabolism of Acenocoumarol can be decreased when combined with Caffeine.

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Caffeine.

Anagrelide

Major

The metabolism of Anagrelide can be decreased when combined with Caffeine.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Caffeine.

Bendamustine

Major

The metabolism of Bendamustine can be decreased when combined with Caffeine.

Caffeine Citrate Toxicity & Overdose Risk

The lowest toxic dose of caffeine for rats is 192mg/kg. In humans, an acute fatal overdose is around 10-14 grams, which is equal to 150-200mg/kg of body weight. Signs of an overdose include nausea, vomiting, diarrhea, agitation, restlessness, insomnia, fast heartbeat, tremors, and in extreme cases, death. To treat an overdose, offer symptomatic treatment for mild cases and intubation and activated charcoal for severe cases. Benzodiazepines can be used to prevent or treat seizures, IV fluids and vasopressors can be used to combat hypotension, and magnesium and beta

Caffeine Citrate Novel Uses: Which Conditions Have a Clinical Trial Featuring Caffeine Citrate?

At present, 429 active studies are investigating the potential of Caffeine Citrate to relieve Chronic Fatigue Syndrome, Chronic Pain and Migraine.

Condition

Clinical Trials

Trial Phases

Influenza

29 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3

Pain relief

15 Actively Recruiting

Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1

Chronic Pain

130 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1

Chronic Fatigue Syndrome

43 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4

Indigestion

6 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Respiratory Insufficiency

0 Actively Recruiting

Migraine

13 Actively Recruiting

Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4

Premature Birth

4 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Catarrh

0 Actively Recruiting

Vascular Headaches

0 Actively Recruiting

Tension-Type Headache

0 Actively Recruiting

Athletic Performance

1 Actively Recruiting

Not Applicable

Eye

1 Actively Recruiting

Not Applicable

Toothache

0 Actively Recruiting

Muscle Pain

3 Actively Recruiting

Phase 4, Not Applicable, Phase 2

Sleepiness

4 Actively Recruiting

Not Applicable, Phase 3

Pain

0 Actively Recruiting

Fever

2 Actively Recruiting

Not Applicable, Phase 4

Mental Depression

0 Actively Recruiting

Pain management

0 Actively Recruiting

Patient Q&A Section about caffeine citrate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is caffeine citrate the same as caffeine?

"The dose of caffeine base should be half the dose of caffeine citrate. Serum concentrations of caffeine may need to be monitored periodically to avoid toxicity."

Answered by AI

What are the common side effects of caffeine citrate?

"Notify your doctor if you experience any of the following side effects which may persist or worsen: nausea, vomiting, stomach upset, headache, trouble sleeping, restlessness, poor feeding, increased urination, rash or dry skin."

Answered by AI

What is caffeine citrate used for?

"Caffeine citrate injection is used to treat short-term apnea of prematurity in premature babies when their breathing centers are not fully developed."

Answered by AI

Can caffeine citrate be used in adults?

"The usual maintenance dose of caffeine citrate is 5 to 10 mg per kilogram of body weight per day, equivalent to 2.5 to 5 mg per kilogram of body weight per day of anhydrous caffeine base. Higher doses up to 20 mg per kilogram of body weight per day of caffeine citrate (equivalent to 10 mg per kilogram of body weight per day of anhydrous caffeine base) have occasionally been necessary. Treatment usually lasts for at least 48 hours."

Answered by AI

Clinical Trials for Caffeine Citrate

Image of UCI Health Susan Samueli Integrative Health Institute in Irvine, United States.

Biofield Therapy for Cancer

18+
All Sexes
Irvine, CA

Cancer treatment with immunotherapy is often associated with symptoms such as fatigue, pain, and emotional distress, which may affect patients' daily functioning and quality of life. Additional supportive care approaches are being studied to better understand their potential role in supporting these symptoms. The purpose of this study is to learn whether a biofield therapy, called Reiki may help to support adults with cancer who are receiving immunotherapy and currently struggling with fatigue. Reiki is a non-invasive complementary therapy delivered by a trained practitioner who places their hands lightly near the body. It is intended to promote relaxation and support general well-being. Reiki is used as a supportive practice and is not considered a medical treatment or replacement for standard care. The secondary goal of this study is to evaluate the feasibility of delivering Reiki in this clinical setting. This includes examining recruitment, retention, adherence to study procedures, and overall participant engagement. Lastly, the third aim is to explore participants' experiences with Reiki through guided interviews. Participants enrolled in this study will first be asked to participate in a one-hour, one-on-one interview about their experiences with cancer treatment, their symptoms, and their thoughts about integrative care practices such as Reiki. After the interview, they will be randomly assigned to one of two groups: Immediate Reiki Group: If participants are assigned to this group, they will receive six weekly, in-person 30-minute Usui Reiki sessions from a Reiki master at the Susan Samueli Integrative Health Institute. Before and after each session, participants will complete questionnaires about fatigue, pain, and stress. At the first and final sessions, a small blood sample will be collected to measure inflammatory biomarkers, and Electroencephalogram (EEG) hyperscanning will be conducted to measure brain activity and connectivity between the participant and the practitioner. Four weeks after the final session, they will complete the questionnaires again, followed by a short satisfaction survey about their experience. Waitlist Group: If they are assigned to the waitlist group, they will first complete a 6-week observation period that includes brief weekly fatigue questionnaires and two in-person 30-minute sessions with EEG measurements at Week 1 and Week 6. This will be followed by a 4-week period with no sessions, after which they will complete questionnaires about fatigue, pain, and psychological distress. Participants will then begin the same six weekly, in-person 30-minute sessions described above. As with the Immediate Group, they will complete questionnaires before and after each session. At the first and final sessions, a small blood sample will be collected and EEG hyperscanning will be conducted. At the end of the study, participants will also complete a short satisfaction survey about their experience. The investigators hypothesize that participants receiving Reiki will report improvements in symptoms and well-being compared to those not yet receiving Reiki, and that the intervention will be feasible to implement and acceptable to participants.

Recruiting
Has No Placebo

UCI Health Susan Samueli Integrative Health Institute (+1 Sites)

Image of Foothills Medical Centre in Calgary, Canada.

Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis

18 - 65
All Sexes
Calgary, Canada

Canada has one of the highest rates of multiple sclerosis (MS). MS patients experience disabling motor, visual, and sensory symptoms, and a high risk of comorbid major depressive disorder (MDD) and severe fatigue. The lifetime prevalence of MDD in MS patients is about 50%, and nearly 90% experience severe fatigue, both of which are not responsive to typical treatments. Repetitive transcranial magnetic stimulation (rTMS) is a first line, Health Canada approved non-invasive neurostimulation treatment for MDD. rTMS induces electrical activity in the cortex using magnetic fields generated outside of the head to drive neuronal firing in the target site. However, MS is typically an exclusion criterion due to safety concerns. The goal of this clinical trial is to learn if repeated transcranial magnetic stimulation (rTMS) can be used to treat depression symptoms in adults with multiple sclerosis (MS). rTMS is a non-invasive form of brain stimulation that uses magnetic pulses to stimulate specific parts of the brain. The main questions it aims to answer are: Is rTMS safe, tolerable, and feasible to deliver as a treatment for depression and fatigue symptoms in individuals with MS? Does rTMS show preliminary effectiveness in improving depression and fatigue symptoms in this population? Researchers will determine whether rTMS treatment improves mood, fatigue, and cognition across time points (baseline, after treatment, and 4-week follow-up). Participants will: Complete screening, questionnaires, clinical assessments, cognitive tests, a brain MRI to help tailor the TMS treatment, and receive daily TMS sessions for 5 consecutive days, including: Pre-TMS brain mapping, five rTMS treatments (3 minutes) per day, separated by one hour. A safety and tolerability questionnaire will be administered daily. Complete post-treatment assessments (questionnaires, cognitive tests, psychiatric evaluation). Complete a 4-week follow-up visit, in person or virtually. Wear a fitness tracking watch during the study so researchers can collect activity data remotely. About 20 people will take part in this study through the University of Calgary.

Phase 1
Waitlist Available

Foothills Medical Centre

Adrianna Giuffre, PhD.

Have you considered Caffeine Citrate clinical trials?

We made a collection of clinical trials featuring Caffeine Citrate, we think they might fit your search criteria.
Go to Trials

Have you considered Caffeine Citrate clinical trials?

We made a collection of clinical trials featuring Caffeine Citrate, we think they might fit your search criteria.
Go to Trials
Image of Efforia in New York, United States.

MyVitalC for Sleep and Headaches

Any Age
All Sexes
New York, NY

Sleep disturbance and recurring headaches can negatively affect daily functioning, mood, and productivity. MyVitalC (ESS60 in extra virgin olive oil) is a commercially available dietary supplement that has generated anecdotal claims related to sleep quality and headache relief; however, human data remain limited. This real-world observational study is designed to help participants evaluate whether use of MyVitalC is associated with changes in sleep disturbance and headache frequency or severity in their own daily lives. Participants will complete a four-week baseline observation period without the intervention, followed by six weeks of daily MyVitalC use, with weekly self-reported assessments. Participants serve as their own control, allowing for within-person comparison of outcomes before and during product use.

Recruiting
Has No Placebo

Efforia

Efforia, Inc

Have you considered Caffeine Citrate clinical trials?

We made a collection of clinical trials featuring Caffeine Citrate, we think they might fit your search criteria.
Go to Trials