Caffeine Citrate

Vascular Headaches, Indigestion, Toothache + 20 more

Treatment

12 FDA approvals

20 Active Studies for Caffeine Citrate

What is Caffeine Citrate

Caffeine

The Generic name of this drug

Treatment Summary

Caffeine is a drug used to treat several conditions, such as respiratory issues in premature babies, pain relief, and drowsiness. It is found naturally in coffee beans, teas, and cacao beans. It is sometimes used in cosmetic products and can be taken orally, by inhalation, or by injection. Caffeine citrate injection is approved by the FDA and is used to treat apnea of the premature newborn. It is helpful in preventing and treating apnea and bronchopulmonary dysplasia in premature infants, which can lead to asthma and early onset emphysema.

Cafergot

is the brand name

image of different drug pills on a surface

Caffeine Citrate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Cafergot

Caffeine

1953

390

Approved as Treatment by the FDA

Caffeine, also called Cafergot, is approved by the FDA for 12 uses including Drug Overdose and Tension Headache .

Drug Overdose

Tension Headache

Used to treat Tension Headache in combination with Acetylsalicylic acid

central nervous system depression

Respiratory Insufficiency

Chronic Fatigue Syndrome

Vascular Headaches

Used to treat Vascular Headaches in combination with Ergotamine

Fatigue

Pain

Used to treat Pain in combination with Acetaminophen

Mental Depression

Pain

Used to treat moderate Pain in combination with Acetaminophen

Chronic Pain

Used to treat Pain in combination with Acetaminophen

Tension-Type Headache

Used to treat Tension Headache in combination with Acetylsalicylic acid

Effectiveness

How Caffeine Citrate Affects Patients

Caffeine can make people feel more alert and active, but can also lead to feeling jittery and restless. Caffeine also helps to relax certain muscles, make the heart beat faster, and can improve athletic performance. It can also increase stomach acid and help with digestion, as well as help relieve migraine and other types of headaches when combined with other medications. Lastly, caffeine acts as a mild diuretic.

How Caffeine Citrate works in the body

Caffeine affects many body systems in various ways. It can reduce drowsiness by blocking adenosine receptors in the brain, and can have a diuretic effect by increasing sodium excretion in the kidneys. In the heart, caffeine can increase heart rate and blood pressure, while also widening blood vessels. This helps to relieve migraines and headaches, which are often caused by narrowed vessels in the brain. Caffeine also has other effects on cells, but the clinical relevance of these is not well understood.

When to interrupt dosage

The quantity of Caffeine Citrate is contingent upon the diagnosed condition, including Overdose, Drug, Catarrh and Athletic Performance. The amount also changes as per the technique of delivery (e.g. Tablet or Tablet - Oral) presented in the table beneath.

Condition

Dosage

Administration

Eye

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Catarrh

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain relief

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Tension-Type Headache

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Acute Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Toothache

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Pain management

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Athletic Performance

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Vascular Headaches

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Indigestion

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Chronic Fatigue Syndrome

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Muscle Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Bronchopulmonary Dysplasia

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Chronic Pain

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Migraine

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Sleepiness

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Fever

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Influenza

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Antacid therapy

65.0 mg, , 40.0 mg, 100.0 mg, 60.0 mg, 35.5 mg, 32.5 mg, 32.0 mg, 20.0 mg/mL, 125.0 mg/mL, 32.4 mg, 200.0 mg, 20.0 mg, 4.0 mg/mL, 30.0 mg, 50.0 mg, 1.0 mg, 0.005 mg/mL, 0.0125 mg/mL, 6.5 mg/mL, 4.0 mg, 2.0 mg, 6.0 mg, 0.002 mg/mg, 15.0 mg, 16.2 mg, 175.0 mg, 16.0 mg, 33.0 mg, 2.0 mg/mg, 0.27 mg/mg, 150.0 mg, 33.3 mg, 16.3 mg, 38.0 mg, 75.0 mg, 60.0 mg/mL, 3.0 mg/mL, 0.5 mg/mL, 0.1 mg/mL, 25.0 mg/mL, 0.008 mg/mg, 6.3 mg/mL, 10.0 mg/mL

, Tablet, film coated - Oral, Tablet, film coated, Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Capsule - Oral, Tablet - Oral, Tablet, Capsule, Capsule, liquid filled, Capsule, liquid filled - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Injection, solution - Intramuscular; Intravenous, Intramuscular; Intravenous, Injection, Injection - Intravenous, Suppository, Suppository - Rectal, Rectal, Tablet, multilayer, Tablet, multilayer - Oral, Solution, Solution - Intravenous, Solution - Oral, Syrup - Oral, Powder, Powder - Oral, Cream, Topical, Cream - Topical, Liquid - Oral, Liquid, Capsule, coated - Oral, Capsule, coated, Granule, Granule - Oral, Tablet, effervescent, Tablet, effervescent - Oral, Syrup, Wafer - Oral, Wafer, Intravenous; Oral, Injection, solution; Solution - Intravenous; Oral, Injection, solution; Solution, Kit, Lozenge, Lozenge - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Tablet, film coated - Topical, Solution - Intravenous; Oral, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Tablet, extended release, Tablet, extended release - Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Powder - Topical, Kit - Oral, Granule, for solution, Granule, for solution - Oral, Kit - Oral; Respiratory (inhalation); Topical, Kit - Ophthalmic; Oral; Topical, Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Topical

Warnings

Caffeine Citrate has one contraindication, so it should not be consumed for the conditions listed in the following table.

Caffeine Citrate Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Caffeine may interact with Pulse Frequency

There are 20 known major drug interactions with Caffeine Citrate.

Common Caffeine Citrate Drug Interactions

Drug Name

Risk Level

Description

Acenocoumarol

Major

The metabolism of Acenocoumarol can be decreased when combined with Caffeine.

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Caffeine.

Anagrelide

Major

The metabolism of Anagrelide can be decreased when combined with Caffeine.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Caffeine.

Bendamustine

Major

The metabolism of Bendamustine can be decreased when combined with Caffeine.

Caffeine Citrate Toxicity & Overdose Risk

The lowest toxic dose of caffeine for rats is 192mg/kg. In humans, an acute fatal overdose is around 10-14 grams, which is equal to 150-200mg/kg of body weight. Signs of an overdose include nausea, vomiting, diarrhea, agitation, restlessness, insomnia, fast heartbeat, tremors, and in extreme cases, death. To treat an overdose, offer symptomatic treatment for mild cases and intubation and activated charcoal for severe cases. Benzodiazepines can be used to prevent or treat seizures, IV fluids and vasopressors can be used to combat hypotension, and magnesium and beta

Caffeine Citrate Novel Uses: Which Conditions Have a Clinical Trial Featuring Caffeine Citrate?

At present, 429 active studies are investigating the potential of Caffeine Citrate to relieve Chronic Fatigue Syndrome, Chronic Pain and Migraine.

Condition

Clinical Trials

Trial Phases

Influenza

29 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 1, Phase 3

Pain relief

15 Actively Recruiting

Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1

Chronic Pain

130 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 3, Early Phase 1, Phase 1

Chronic Fatigue Syndrome

43 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4

Indigestion

6 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Respiratory Insufficiency

0 Actively Recruiting

Migraine

13 Actively Recruiting

Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4

Premature Birth

4 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Catarrh

0 Actively Recruiting

Vascular Headaches

0 Actively Recruiting

Tension-Type Headache

0 Actively Recruiting

Athletic Performance

1 Actively Recruiting

Not Applicable

Eye

1 Actively Recruiting

Not Applicable

Toothache

0 Actively Recruiting

Muscle Pain

3 Actively Recruiting

Phase 4, Not Applicable, Phase 2

Sleepiness

4 Actively Recruiting

Not Applicable, Phase 3

Pain

0 Actively Recruiting

Fever

2 Actively Recruiting

Not Applicable, Phase 4

Mental Depression

0 Actively Recruiting

Pain management

0 Actively Recruiting

Patient Q&A Section about caffeine citrate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is caffeine citrate the same as caffeine?

"The dose of caffeine base should be half the dose of caffeine citrate. Serum concentrations of caffeine may need to be monitored periodically to avoid toxicity."

Answered by AI

What are the common side effects of caffeine citrate?

"Notify your doctor if you experience any of the following side effects which may persist or worsen: nausea, vomiting, stomach upset, headache, trouble sleeping, restlessness, poor feeding, increased urination, rash or dry skin."

Answered by AI

What is caffeine citrate used for?

"Caffeine citrate injection is used to treat short-term apnea of prematurity in premature babies when their breathing centers are not fully developed."

Answered by AI

Can caffeine citrate be used in adults?

"The usual maintenance dose of caffeine citrate is 5 to 10 mg per kilogram of body weight per day, equivalent to 2.5 to 5 mg per kilogram of body weight per day of anhydrous caffeine base. Higher doses up to 20 mg per kilogram of body weight per day of caffeine citrate (equivalent to 10 mg per kilogram of body weight per day of anhydrous caffeine base) have occasionally been necessary. Treatment usually lasts for at least 48 hours."

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Clinical Trials for Caffeine Citrate

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

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Image of Arizona State University in Phoenix, United States.

App-based Breathing Program for Migraine

18+
All Sexes
Phoenix, AZ

Migraine is one of the most common neurological disorders, characterized by recurrent headaches, sensitivity to light and movement, nausea, and autonomic dysregulation. Although mind-body interventions like biofeedback have shown their efficacy, they remain underutilized due to barriers such as transportation, time constraints, lack of awareness, stigma, and cost. A targeted approach to enhancing HRV is HRV biofeedback (HRVB), a technique using visual or auditory feedback to help people regulate HRV through slow-paced breathing and positive emotional regulation to promote ANS balance and emotional resilience. Investigators will conduct a remotely delivered pilot RCT of an 8-week, 10 min/day, novel app-based HRVB intervention compared to a sham control intervention (matching intervention time and attention with no biofeedback component) in adult with chronic migraine. Investigators hypothesize data collected from the study will: a) support the feasibility and acceptability of the remotely delivered app-based HRVB intervention among adults with chronic migraine, and b) provide insights into refining the intervention by examining patterns of change in migraine and psychological outcomes from pre- to post-intervention.

Waitlist Available
Online Trial

Arizona State University

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Image of BTT Medical Institute Aventura North in Miami, United States.

Niagen®Plus for Fatigue

18+
All Sexes
Miami, FL

The goal of this study is to learn about the safety of Niagen®Plus, an injectable form of nicotinamide riboside (NR), and to see how it affects levels of NAD+ in the blood. Niagen®Plus will be given either by subcutaneous (under the skin) or intramuscular (into the muscle) injection at two dose levels (50 mg or 100 mg). The main questions this study aims to answer are: Is Niagen®Plus safe and well-tolerated when given by injection several times over 100 days? How do NAD+ levels in blood change after repeated doses of Niagen®Plus? What are participants' and clinicians' experiences with the injections? Researchers will also look at changes in fatigue, sleep, quality of life, inflammation markers, mitochondrial efficiency, and perceived skin appearance. Participants will: Receive three injections in clinic on Days 1-3, followed by a Day 10 follow-up visit Self-inject Niagen®Plus at home three times per week from Days 10-100 Return to the clinic on Days 40 and 100 for safety and laboratory testing Complete short surveys about fatigue, sleep, and overall well-being throughout the study The study will include 40 generally healthy adults and will last about 100 days per participant.

Phase 1
Recruiting

BTT Medical Institute Aventura North

ChromaDex, Inc.

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