Questran Light

Hardening of the Arteries, partial biliary obstruction, Itching + 1 more
Treatment
5 FDA approvals
20 Active Studies for Questran Light

What is Questran Light

CholestyramineThe Generic name of this drug
Treatment SummaryCholestyramine is a medication that helps your body get rid of bile acid. It is a type of polymeric compound that binds to bile acid and helps it be eliminated from the body. Cholestyramine is not soluble in water, but it is very good at absorbing liquids.
Cholestyramine Lightis the brand name
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Questran Light Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Cholestyramine Light
Cholestyramine
1994
47

Approved as Treatment by the FDA

Cholestyramine, commonly known as Cholestyramine Light, is approved by the FDA for 5 uses like Hardening of the Arteries and Itching .
Hardening of the Arteries
Helps manage Atherosclerosis
Itching
partial biliary obstruction
Primary Hypercholesterolemia
Pruritus

Effectiveness

How Questran Light Affects PatientsCholesterol is needed to create bile acids, which help with digestion. Normally, bile acids are secreted into the intestines and absorbed back into the liver. Cholestyramine resin binds with the bile acids in the intestines, forming an insoluble complex that gets passed out in the feces. This helps to prevent the bile acids from being reabsorbed and thus lowers their levels in the body.
How Questran Light works in the bodyCholestyramine is a medication that helps reduce the reabsorption of bile acids in the digestive tract. It works by sticking to anionic bile acids and forming a strong resin matrix. This creates an exchange of chloride anions with the bile acid particles. The medication is made up of a quaternary ammonium group attached to an inert styrene-divinylbenzene copolymer.

When to interrupt dosage

The measure of Questran Light rests on the diagnosed condition, such as Hardening of the arteries, Itch and Primary Hypercholesterolemia. The portion likewise changes in accordance with the mode of delivery (e.g. Oral or Powder, for suspension) given in the table beneath.
Condition
Dosage
Administration
Itching
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
Hardening of the Arteries
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
partial biliary obstruction
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral
Primary Hypercholesterolemia
, 4.0 mg/mg, 4000.0 mg, 1000.0 mg, 400000.0 mg, 4000.0 mg/dose
, Oral, Powder, for suspension, Powder, for suspension - Oral, Powder, for solution, Powder, for solution - Oral, Tablet, Tablet - Oral, Kit; Powder, Kit; Powder - Oral, Powder, Powder - Oral, Powder; Suspension, Powder; Suspension - Oral

Warnings

Questran Light Contraindications
Condition
Risk Level
Notes
complete biliary obstruction
Do Not Combine
There are 20 known major drug interactions with Questran Light.
Common Questran Light Drug Interactions
Drug Name
Risk Level
Description
Mycophenolate mofetil
Major
Cholestyramine may increase the excretion rate of Mycophenolate mofetil which could result in a lower serum level and potentially a reduction in efficacy.
Mycophenolic acid
Major
Cholestyramine may increase the excretion rate of Mycophenolic acid which could result in a lower serum level and potentially a reduction in efficacy.
Raloxifene
Major
Cholestyramine can cause a decrease in the absorption of Raloxifene resulting in a reduced serum concentration and potentially a decrease in efficacy.
(R)-warfarin
Minor
Cholestyramine can cause a decrease in the absorption of (R)-warfarin resulting in a reduced serum concentration and potentially a decrease in efficacy.
(S)-Warfarin
Minor
Cholestyramine can cause a decrease in the absorption of (S)-Warfarin resulting in a reduced serum concentration and potentially a decrease in efficacy.
Questran Light Toxicity & Overdose RiskOverdosing on the drug may lead to an obstruction in the stomach or intestines.
image of a doctor in a lab doing drug, clinical research

Questran Light Novel Uses: Which Conditions Have a Clinical Trial Featuring Questran Light?

68 active studies are in progress to assess the potential of Questran Light to ameliorate Itch, partial biliary obstruction, and Primary Hypercholesterolemia.
Condition
Clinical Trials
Trial Phases
Primary Hypercholesterolemia
10 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Itching
3 Actively Recruiting
Phase 2, Phase 3, Not Applicable
partial biliary obstruction
0 Actively Recruiting
Hardening of the Arteries
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Phase 1

Questran Light Reviews: What are patients saying about Questran Light?

5Patient Review
4/7/2015
Questran Light for Chronic Diarrhea
This medication has been a life-saver. I was struggling with severe diarrhea and couldn't leave the house without constant worry. After just six months of taking one sachet per day, I no longer have any issues.
5Patient Review
5/25/2012
Questran Light for Chronic Diarrhea
I've been struggling with chronic diarrhea for six years now, and this medication has finally allowed me to have some semblance of a normal life again. I can't thank Questran enough!
5Patient Review
2/22/2008
Questran Light for Chronic Diarrhea
4.7Patient Review
1/19/2019
Questran Light for Chronic Diarrhea
Questtan Lite has been a godsend for my Lymphocytic Colitis. I was on steroids for two months prior, but I was still having to use the restroom several times per day. Since starting this medication, though, that urgency has gone away and I've had fewer trips to the bathroom overall.
4.7Patient Review
10/26/2009
Questran Light for Chronic Diarrhea
Questran Light has been fantastic for me since having my gallbladder removed. It's completely stopped the chronic diarrhea I was experiencing. The only downside is the powdery texture, which makes it a bit difficult to take.
View All Reviews
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Patient Q&A Section about questran light

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Questran Light used for?

"This medicine helps to lower your body's cholesterol levels, which can reduce your risk of heart disease. It works by adsorbing bile acids containing cholesterol in the digestive system, which are then eliminated from the body in the faeces."

Answered by AI

What are the side effects of Questran Lite?

"The following effects may occur: constipation, stomach/abdominal pain, gas, nausea, or vomiting. If you experience any of these effects, tell your doctor or pharmacist."

Answered by AI

When should I take Questran?

"This medication is to be taken as prescribed by your doctor. The medication should be taken before a meal and/or at bedtime. Any other medications should be taken at least 1 hour before or 4 hours after you take cholestyramine to avoid interference with absorption."

Answered by AI

Is there an alternative to Questran Light?

"If questran & colesevelam are not available from your local pharmacies, colestipol granules (Brand name Cholestid) is the only alternative bile acid sequestrant available."

Answered by AI

Clinical Trials for Questran Light

Have you considered Questran Light clinical trials? We made a collection of clinical trials featuring Questran Light, we think they might fit your search criteria.
Have you considered Questran Light clinical trials? We made a collection of clinical trials featuring Questran Light, we think they might fit your search criteria.
Have you considered Questran Light clinical trials? We made a collection of clinical trials featuring Questran Light, we think they might fit your search criteria.