Oxtellar Xr

Seizures
Treatment
2 FDA approvals
4 Active Studies for Oxtellar Xr

What is Oxtellar Xr

OxcarbazepineThe Generic name of this drug
Treatment SummaryOxcarbazepine is a prescription drug used to treat partial onset seizures. It was first approved for use in the United States in 2000 and is a derivative of Carbamazepine, another anti-epileptic medication. Oxcarbazepine is metabolized differently than other anti-epileptic drugs, which reduces its potential to interact with other medications. It is marketed under the name Eslicarbazepine as well.
Trileptalis the brand name
Oxtellar Xr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Trileptal
Oxcarbazepine
2000
156

Approved as Treatment by the FDA

Oxcarbazepine, also called Trileptal, is approved by the FDA for 2 uses including Partial-Onset Seizures and Seizures .
Partial-Onset Seizures
Seizures

Effectiveness

How Oxtellar Xr Affects PatientsOxcarbazepine is a medicine used to prevent seizures in people with epilepsy. It works by stopping abnormal electrical activity in the brain. This drug can cause rare blood disorders, so people taking it should be tested regularly and watched for any signs of blood-related problems. It can also lead to skin reactions ranging from mild rashes to very serious conditions such as toxic epidermal necrolysis or Stevens-Johnson Syndrome. People with certain gene variations may be at higher risk for these reactions and should stop taking oxcarbazepine if they experience any skin reactions.
How Oxtellar Xr works in the bodyOxcarbazepine and its active metabolite, MHD, help to prevent seizures by blocking the pathways that allow neurons to fire excessively. They do this by binding to inactive voltage-gated sodium channels, which helps stabilize the cells and prevents too much activity. Additionally, oxcarbazepine helps with potassium conductance and calcium channels. It was previously thought to work by blocking glutamate activity, but this has been disproven.

When to interrupt dosage

The suggested dosage of Oxtellar Xr is contingent upon the diagnosed disorder. The measure of dosage can be seen in the table underneath, contingent upon the technique of delivery.
Condition
Dosage
Administration
Seizures
150.0 mg, 300.0 mg, 600.0 mg, , 60.0 mg/mL, 300.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Suspension, Suspension - Oral, Tablet, Tablet - Oral

Warnings

Oxtellar Xr Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Oxcarbazepine may interact with Pulse Frequency
There are 20 known major drug interactions with Oxtellar Xr.
Common Oxtellar Xr Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Oxcarbazepine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Oxcarbazepine.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Oxcarbazepine.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Oxcarbazepine.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Oxcarbazepine.
Oxtellar Xr Toxicity & Overdose RiskThe toxic dose of oxcarbazepine in mammals is 1240 mg/kg. Cases of overdoses have been reported, with one person taking up to 24,000mg and recovering with medical treatment. Symptoms of an overdose may include difficulty breathing, confusion, nausea and vomiting, low sodium levels, or a prolonged QT interval on an ECG. There is no antidote for oxcarbazepine overdose, so medical care should focus on relieving symptoms and possibly using gastric lavage or activated charcoal.

Oxtellar Xr Novel Uses: Which Conditions Have a Clinical Trial Featuring Oxtellar Xr?

Two active clinical trials are being conducted to assess the ability of Oxtellar Xr to provide therapeutic benefits to patients suffering from Seizures.
Condition
Clinical Trials
Trial Phases
Seizures
4 Actively Recruiting
Phase 3, Phase 2

Oxtellar Xr Reviews: What are patients saying about Oxtellar Xr?

5Patient Review
10/19/2016
Oxtellar Xr for Simple Seizure
About seven months ago, my doctor switched me from Oxcarbazapine to Oxtellar XR for absence seizures. I used to constantly feel tired on the old medication and would often have bad dreams. However, since switching to Oxtellar I've been able to stay awake and the bad dreams are gone. It took a few months to get used to the change, but once I did I felt like a normal person again.
5Patient Review
7/31/2014
Oxtellar Xr for Simple Partial Seizures
Since adding Oxtellar XR to my Keppra regimen, I've only had one seizure in the last two months. This medication has been life-changing!
5Patient Review
3/28/2013
Oxtellar Xr for Simple Partial Seizures
I switched from trileptal to Oxtellar and it doesn't make me dizzy and has reduced my seizures.
4.7Patient Review
3/6/2018
Oxtellar Xr for Facial Nerve Pain
I've been struggling with Trigeminal Neuralgia for four years now, and I tried a lot of different medications before finally finding Oxtellar Xr. Once my doctor found the right dosage (600mg per day), my symptoms completely vanished. If you're suffering from this terrible disease, I urge you to give this medication a try-- it really changed my life.
4.3Patient Review
7/30/2013
Oxtellar Xr for Simple Partial Seizures
Though this medication is effective for simple partial seizures, I unfortunately had an allergic reaction to it. Once I was made aware of the sulphur content, it became clear that that was the root of the problem.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about oxtellar xr

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there a generic for Oxtellar XR?

"Oxtellar XR is used to treat epilepsy and is less popular than comparable drugs. There is no generic alternative for Oxtellar XR."

Answered by AI

Is Oxtellar XR the same as Trileptal?

"The drugs oxcarbazepine and Trileptal are from Novartis Pharmaceuticals, and Supernus Pharmaceuticals make an extended release version of the drug that can be taken once a day."

Answered by AI

When should I take Oxtellar XR?

"You should take Oxtellar XR at least 1 hour before or at least 2 hours after a meal. Take Oxtellar XR tablets whole with water or other liquid. Do not cut, crush, or chew the tablets before swallowing."

Answered by AI

What is Oxtellar XR used for?

"Oxtellar XR is a prescription medication used to treat partial-onset seizures in people with epilepsy who are 6 years of age or older. It may be used alone or in combination with other drugs to treat this condition. Partial-onset seizures are also referred to as focal-onset seizures."

Answered by AI

Clinical Trials for Oxtellar Xr

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