This trial is evaluating whether Brivaracetam will improve 1 primary outcome and 1 secondary outcome in patients with Neoplasms, Brain. Measurement will happen over the course of 6 Months.
This trial requires 30 total participants across 1 different treatment group
This trial involves a single treatment. Brivaracetam is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are in Phase < 1 and are in the first stage of evaluation with people.
"There are no single treatments for neoplasms, brain that are widely used or even acceptable. The most commonly used treatments for neoplasms, brain are radiotherapy, chemotherapy with chemotherapy drugs such as methotrexate, 5-fluorouracil, carboplatin, or irinotecan, surgical resection and corticosteroids." - Anonymous Online Contributor
"The brain is exposed to high levels of radiation and pollutants during infancy. These factors increase the risk of developing benign neoplasms and secondary brain tumors in adulthood.\n" - Anonymous Online Contributor
"Brain tumours may cause headaches, speech problems, vomiting or seizures. In children, an unsteady gait or loss of fine motor skills may be signs of brain tumours. A headache at the same place as the tumour could be signs of a brain tumour." - Anonymous Online Contributor
"Approximately 4.0 million US citizens are diagnosed with brain cancer and 2.5 million die of the disease annually. However, the number of individuals affected can reach up to 50% amongst those who survive brain cancer.\n" - Anonymous Online Contributor
"Brain neoplasms are rare and are usually associated with a history of neurological disease. These diseases include epilepsy, epilepsy-related intracranial lesions, and demyelinating syndromes. When CNS neoplasms are suspected, evaluation of CT, MRI, and PET scan results is mandatory." - Anonymous Online Contributor
"Neither can neoplasms, nor brain be cured from all causes. These concepts have to rely on rigorous protocols for diagnostic and therapeutic management, as well as intensive support from professionals to enable the patient to cope with the pain until he is free from it." - Anonymous Online Contributor
"In the majority of families with neoplasms involving the brain, the predisposition is autosomal dominant. The risk for neoplasms of the brain in siblings with neoplasms of the kidney is approximately 50% with autosomal dominance and 10% with the recessive mode. There remain unanswered questions regarding the genetic influences on neoplasms of brain, the mechanism of renal adenomatoblastomas, and the relevance of the occurrence of neoplasms of the brain in families with neoplasms of the kidneys." - Anonymous Online Contributor
"A new treatment has been developed for acute leukemia, a neoplasm of chronic immune disease. It is a highly specific fusion protein-targeted small molecule antineoplastic (a targeted anticancer drug). It shows promise of being an effective treatment for this devastating disease. This new treatment can be used to treat patients under current standard treatments, and is in phase II testing to determine its safety and efficacy." - Anonymous Online Contributor
"Although brivaracetam shows promise in improving cognitive functioning in patients with nonmotor symptoms of Alzheimer's disease, the results were in the range of that seen in healthy elderly controls. However, results in subcortical atrophy and neuropsychiatric disturbances were promising, but were restricted to a single pilot trial. Further randomized, controlled trials are needed to establish brivaracetam as an effective alternative to placebo." - Anonymous Online Contributor
"An additional study is needed to establish the relation between the age of the patient and the time to spread of brain metastasis if one exists. At present there is no relation: that is, when a patient is younger than 55 years and the metastatic lesion is small, brain metastasis should not spread, while for tumors larger than the size of a walnut, metastasis is more common among patients aged 55-65 years." - Anonymous Online Contributor
"Although the survival rate in children and adolescents is generally excellent, in young adults with brain tumors, it is significantly poorer. There should be a focus on early diagnosis and treatment for children with brain tumors." - Anonymous Online Contributor
"Patients with neurologic deficits that are reversible or treatable may benefit from clinical trials. Clinicians should be aware that some cancer trials for neoplasms do not provide any benefit, but many of those that do provide benefit cannot be used to treat patients owing to ethical issues." - Anonymous Online Contributor