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What is Periostat
DoxycyclineThe Generic name of this drug
Treatment SummaryDoxycycline is an antibiotic used to treat a wide range of bacterial infections. It is a synthetically derived version of the tetracycline family of antibiotics, with fewer side effects than the first-generation tetracyclines. Its effectiveness against specific bacteria can be determined through antibiotic susceptibility testing.
Vibramycin Hyclateis the brand name
Periostat Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vibramycin Hyclate
Doxycycline
1967
728
Approved as Treatment by the FDA
Doxycycline, otherwise known as Vibramycin Hyclate, is approved by the FDA for 93 uses such as Plasmodium Infections and Anal chlamydia infection .Plasmodium Infections
Anal chlamydia infection
Upper Respiratory Tract Infection
Streptococcus Pneumoniae Infections
Yaws
Brucellosis
Used to treat Brucellosis in combination with Streptomycin
Genus Chlamydia
Chlamydia Infections
Calymmatobacterium granulomatis
Actinomycosis
Rickettsialpox
Necrotizing ulcerative gingivostomatitis
Klebsiella Infections
Mycoplasma Pneumoniae
Trachoma
Shigella Infection
Epididymo-orchitis gonococcal
Fever
Bartonella bacilliformis infections
Acinetobacter Infections
Psittacosis
Chlamydia psitacci infection
Plague
Yersinia pestis
Ureaplasma urethritis
Trachoma inclusion conjunctivitis
Campylobacter Infections
Inclusion conjunctivitis
Chlamydia Infections
Urethritis
Clostridium difficile Infection
Campylobacter Infection
Ureaplasma Infections
Chlamydial Urethritis
Infection Due to Escherichia Coli
inhaled anthrax caused by Bacillus anthracis
Rocky Mountain Spotted Fever
Severe Acne
Typhus, Endemic Flea-Borne
Communicable Diseases
Listeria infection
Typhus infections
Skin Infections
Urinary Tract Infections
Bacteriological Techniques
Dysentery, Bacillary
Gonorrhea
Bartonella Infections
Acne Vulgaris
Q Fever
Acinetobacter Infections
Ureaplasma Infections
Plague
Communicable Diseases
Uterine Cervicitis
Primary Syphilis
Tularemia
Malaria
Relapsing Fever
Amebic colitis
Tick-borne fever
Chlamydia trachomatis
Recurrent Upper and Lower Respiratory Tract Infections (RTIs)
Chlamydia trachomatis
Bacterial Infection caused by Enterobacter aerogenes
Pneumococcal Infections
Staphylococcus (S.) Aureus Infection
Clostridium Infections
Common Cold
Haemophilus Influenzae Infections
Brucellosis
Used to treat Brucellosis in combination with Streptomycin
Relapsing fever caused by Borrelia recurrentis
Secondary Syphilis
Lymphogranuloma Venereum
Intestinal Amebiasis
Cholera (Disorder)
Communicable Diseases
Trachoma
Chancroid
Neisseria Gonorrhoeae Infection
Cat-Scratch Disease
Urethritis
Chlamydial cervicitis
Listeriosis
Yaws
Relapsing Fever
Vibrio Cholerae Infection
Disease
Haemophilus ducreyi infection
Tularemia
prophylaxis of Malaria
Respiratory Tract Infections
Granuloma Inguinale
Effectiveness
How Periostat Affects PatientsDoxycycline and other tetracyclines stop bacteria from growing or keep them in a stationary state. They work against both gram-positive and gram-negative bacteria, and these bacteria are often resistant to tetracyclines. Doxycycline is a lipophilic drug, which means it can penetrate cells and has a wide range of effects, such as being antibacterial, antiparasitic, and anti-inflammatory. It has been used to treat skin conditions such as bullous dermatoses and rosacea.
How Periostat works in the bodyDoxycycline stops bacteria from making necessary proteins that allow them to survive and function. It does this by blocking the binding of amino acids to ribosomes, which are responsible for making proteins. Doxycycline also blocks inflammation by preventing calcium-dependent cells from forming and stopping lymphocytes from growing. It also stops an enzyme that produces a molecule that causes inflammation.
When to interrupt dosage
The prescribed dose of Periostat is reliant upon the diagnosed condition, such as Urethritis, Chlamydia trachomatis and Respiratory Tract Infections. The measure of dosage differs, in accordance with the method of delivery (e.g. Capsule or Syrup - Oral) featured in the table underneath.Condition
Dosage
Administration
Acinetobacter Infections
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Q Fever
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Plague
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Tularemia
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Rickettsialpox
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Chlamydia Infections
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Relapsing Fever
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Mycoplasma Pneumoniae
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Urinary Tract Infections
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Malaria
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Yaws
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Tick-borne fever
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Epididymo-orchitis gonococcal
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Cat-Scratch Disease
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Uterine Cervicitis
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Granuloma Inguinale
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Brucellosis
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Urethritis
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Actinomycosis
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Rosacea
10.0 mg/mL, , 75.0 mg, 100.0 mg, 150.0 mg, 50.0 mg, 200.0 mg, 20.0 mg, 1.0 mg/mg, 40.0 mg, 5.0 mg/mg, 7.5 mg/mg, 25.0 mg/mL, 50.0 mg/mL, 120.0 mg, 60.0 mg, 0.1 mg/mg, 5.0 mg/mL, 8.8 %, 20.0 mg/mL, 0.75 mg/mg, 0.5 mg/mg, 80.0 mg
, Intravenous, Injection, powder, lyophilized, for solution, Injection, powder, lyophilized, for solution - Intravenous, Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated, Tablet, coated - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, delayed release pellets - Oral, Kit, Kit - Oral, Capsule, extended release, Capsule, extended release - Oral, Powder, Powder - Intravenous, Powder, for suspension, Powder, for suspension - Oral, Syrup, Syrup - Oral, For suspension, For suspension - Oral, Gel - Oral, Suspension - Oral, Capsule, Delayed Release - Oral, Capsule, Delayed Release, Oral; Topical, Capsule - Oral; Topical, Injection, powder, for solution, Injection, powder, for solution - Intravenous
Warnings
Periostat has three contraindications and should not be ingested when any of the conditions mentioned in the table below are present.Periostat ContraindicationsCondition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Doxycycline may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Doxycycline may interact with Pulse Frequency
Common Periostat Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Doxycycline.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Doxycycline.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Doxycycline.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Doxycycline.
Amdinocillin
Major
The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Doxycycline.
Periostat Toxicity & Overdose RiskThe toxic dose of doxycycline in rats is 2000mg/kg, 1870mg/kg in mice, and 500mg/kg in dogs. If an overdose happens, doxycycline should be stopped and supportive medical care should be given. Dialysis will not reduce the amount of the drug in the body and is not recommended for overdoses.
Periostat Novel Uses: Which Conditions Have a Clinical Trial Featuring Periostat?
34 ongoing studies are examining the potential of Periostat to combat Haemophilus Influenzae Infections, Respiratory Tract Infections and Amebic Colitis.Condition
Clinical Trials
Trial Phases
Rosacea
4 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2
Staphylococcus (S.) Aureus Infection
3 Actively Recruiting
Phase 4, Phase 1, Phase 2
Tick-borne fever
0 Actively Recruiting
Calymmatobacterium granulomatis
0 Actively Recruiting
Lymphogranuloma Venereum
0 Actively Recruiting
Listeriosis
0 Actively Recruiting
Haemophilus Influenzae Infections
0 Actively Recruiting
Typhus, Endemic Flea-Borne
0 Actively Recruiting
Campylobacter Infections
0 Actively Recruiting
Clostridium difficile Infection
0 Actively Recruiting
Rocky Mountain Spotted Fever
0 Actively Recruiting
Haemophilus ducreyi infection
0 Actively Recruiting
Tularemia
0 Actively Recruiting
Trachoma
1 Actively Recruiting
Phase 4
inhaled anthrax caused by Bacillus anthracis
0 Actively Recruiting
Pneumococcal Infections
0 Actively Recruiting
Chlamydia Infections
0 Actively Recruiting
Klebsiella Infections
0 Actively Recruiting
Chancroid
0 Actively Recruiting
Tularemia
0 Actively Recruiting
Periostat Reviews: What are patients saying about Periostat?
5Patient Review
2/8/2010 I am a smoker with moderate to advanced periodontal disease. My periodontist performed scaling and root planning with localized surgical treatment. After several years in maintenance my condition began to breakdown. I began using periostat and slowly over the next nine months the periodontist noted a decrease in my bleeding and inflammation as well as my pocket depths. This medication has worked from inside my body to help control the inflammation response to my periodontal infection.
2.3Patient Review
3/10/2010 Since having a hysterectomy (not related to periostat), I've been having some serious digestive issues. Bloating, gas, indigestion; the works. I'm currently taking glutamine and probiotics, but I'm not sure if it's the medicine or not. I was on it for years before this happened, and the package did have warnings about long term use.
1Patient Review
10/24/2008 After having some dental work done, my dentist prescribed this medication. However, I had to stop taking it because it resulted in blood in my stool. I also had to stop taking other medications (simvastatin, baby aspirin and Chantix) until the condition clears up.
Patient Q&A Section about periostat
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long should you use Periostat?
"PERIOSTAT is meant to be used for treatment periods of 3 months. It shouldn't be used for more than 3 consecutive three-month periods. There's no need to change the dosage for elderly patients."
Answered by AI
Is Periostat the same as doxycycline?
"Periostat is a drug used to help reduce pocket depth and promote attachment level gain in patients with adult periodontitis. The dosage of Periostat is different from that of doxycycline, which is used to treat infections."
Answered by AI
What is Periostat used for?
"Periostat is used to treat periodontitis, a condition that affects the gums and can cause teeth to become loose or fall out. The standard treatment for periodontitis is scaling and root planing, which is done by a dentist or dental hygienist."
Answered by AI
What is Periostat periodontics?
"Periostat is an orally administered tablet that contains a novel formulation of 23.08mg doxycycline hyclate. It is designed to be taken twice a day as an adjunct to scaling and root planing (SRP), and has been shown to increase clinical attachment level gain and reduce probing depths in patients with chronic periodontitis."
Answered by AI
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