What is Periostat
DoxycyclineThe Generic name of this drug
Treatment SummaryDoxycycline is an antibiotic used to treat a wide range of bacterial infections. It is a synthetically derived version of the tetracycline family of antibiotics, with fewer side effects than the first-generation tetracyclines. Its effectiveness against specific bacteria can be determined through antibiotic susceptibility testing.
Vibramycin Hyclateis the brand name
Periostat Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vibramycin Hyclate
Doxycycline
1967
728
Approved as Treatment by the FDA
Doxycycline, otherwise known as Vibramycin Hyclate, is approved by the FDA for 1 uses such as Brucellosis .Brucellosis
Used to treat Brucellosis in combination with Streptomycin
Effectiveness
How Periostat Affects PatientsDoxycycline and other tetracyclines stop bacteria from growing or keep them in a stationary state. They work against both gram-positive and gram-negative bacteria, and these bacteria are often resistant to tetracyclines. Doxycycline is a lipophilic drug, which means it can penetrate cells and has a wide range of effects, such as being antibacterial, antiparasitic, and anti-inflammatory. It has been used to treat skin conditions such as bullous dermatoses and rosacea.
How Periostat works in the bodyDoxycycline stops bacteria from making necessary proteins that allow them to survive and function. It does this by blocking the binding of amino acids to ribosomes, which are responsible for making proteins. Doxycycline also blocks inflammation by preventing calcium-dependent cells from forming and stopping lymphocytes from growing. It also stops an enzyme that produces a molecule that causes inflammation.
When to interrupt dosage
The prescribed dose of Periostat is reliant upon the diagnosed condition, such as Urethritis, Chlamydia trachomatis and Respiratory Tract Infections. The measure of dosage differs, in accordance with the method of delivery (e.g. Capsule or Syrup - Oral) featured in the table underneath.Condition
Dosage
Administration
Typhus Fever
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Communicable Diseases
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
inhaled anthrax caused by Bacillus anthracis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Respiratory Tract Infections
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Uterine Cervicitis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Severe Acne
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Actinomycosis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Tularemia
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Chlamydia trachomatis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Necrotizing ulcerative gingivostomatitis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Chancroid
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Listeriosis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Amebic colitis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Epididymo-orchitis gonococcal
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
prophylaxis of Malaria
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Disease
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Secondary Syphilis
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Tularemia
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Haemophilus ducreyi infection
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Rosacea
75.0 mg, , 150.0 mg, 50.0 mg/mL, 100.0 mg, 25.0 mg/mL, 50.0 mg, 20.0 mg, 40.0 mg, 1.0 mg/mg, 5.0 mg/mg, 7.5 mg/mg, 80.0 mg, 8.8 %, 10.0 mg/mL, 200.0 mg, 60.0 mg, 120.0 mg, 20.0 mg/mL, 0.75 mg/mg, 0.1 mg/mg, 0.5 mg/mg, 5.0 mg/mL
Capsule, Syrup - Oral, Powder, for suspension - Oral, Capsule - Oral, Powder, for suspension, , Oral, Tablet, Capsule, delayed release pellets - Oral, Tablet, film coated, Tablet, film coated - Oral, Kit, Injection, powder, lyophilized, for solution, Suspension - Oral, Gel - Oral, Kit - Oral, Intravenous, Tablet, delayed release, Syrup, Capsule, gelatin coated, Injection, powder, for solution, Tablet, delayed release - Oral, Tablet, coated - Oral, Injection, powder, lyophilized, for solution - Intravenous, Capsule, gelatin coated - Oral, Capsule, delayed release pellets, Capsule, extended release - Oral, Tablet - Oral, Powder, Oral; Topical, Injection, powder, for solution - Intravenous, Tablet, coated, Capsule - Oral; Topical, Powder - Intravenous, Capsule, extended release, For suspension - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, For suspension
Warnings
Periostat has three contraindications and should not be ingested when any of the conditions mentioned in the table below are present.Periostat ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Doxycycline may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Doxycycline may interact with Toxoplasma Infections
Common Periostat Drug Interactions
Drug Name
Risk Level
Description
Amdinocillin
Major
The therapeutic efficacy of Amdinocillin can be decreased when used in combination with Doxycycline.
Amoxicillin
Major
The therapeutic efficacy of Amoxicillin can be decreased when used in combination with Doxycycline.
Ampicillin
Major
The therapeutic efficacy of Ampicillin can be decreased when used in combination with Doxycycline.
Aspoxicillin
Major
The therapeutic efficacy of Aspoxicillin can be decreased when used in combination with Doxycycline.
Azidocillin
Major
The therapeutic efficacy of Azidocillin can be decreased when used in combination with Doxycycline.
Periostat Toxicity & Overdose RiskThe toxic dose of doxycycline in rats is 2000mg/kg, 1870mg/kg in mice, and 500mg/kg in dogs. If an overdose happens, doxycycline should be stopped and supportive medical care should be given. Dialysis will not reduce the amount of the drug in the body and is not recommended for overdoses.
Periostat Novel Uses: Which Conditions Have a Clinical Trial Featuring Periostat?
34 ongoing studies are examining the potential of Periostat to combat Haemophilus Influenzae Infections, Respiratory Tract Infections and Amebic Colitis.Condition
Clinical Trials
Trial Phases
Severe Acne
0 Actively Recruiting
Q Fever
0 Actively Recruiting
Vibrio Cholerae Infection
0 Actively Recruiting
Lymphogranuloma Venereum
0 Actively Recruiting
Chlamydia Infections
0 Actively Recruiting
Respiratory Tract Infections
1 Actively Recruiting
Phase 3
Haemophilus Influenzae Infections
0 Actively Recruiting
Calymmatobacterium granulomatis
0 Actively Recruiting
Urinary Tract Infection
11 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4
Skin Infections
3 Actively Recruiting
Phase 2, Not Applicable
Listeriosis
0 Actively Recruiting
Epididymo-orchitis gonococcal
0 Actively Recruiting
Tularemia
0 Actively Recruiting
Haemophilus ducreyi infection
0 Actively Recruiting
Typhus Fever
0 Actively Recruiting
Campylobacter Infection
1 Actively Recruiting
Phase 1
Chlamydia Infections
0 Actively Recruiting
Psittacosis
0 Actively Recruiting
Inclusion conjunctivitis
0 Actively Recruiting
Chlamydia trachomatis
1 Actively Recruiting
Phase 2
Periostat Reviews: What are patients saying about Periostat?
5Patient Review
2/8/2010 I am a smoker with moderate to advanced periodontal disease. My periodontist performed scaling and root planning with localized surgical treatment. After several years in maintenance my condition began to breakdown. I began using periostat and slowly over the next nine months the periodontist noted a decrease in my bleeding and inflammation as well as my pocket depths. This medication has worked from inside my body to help control the inflammation response to my periodontal infection.
2.3Patient Review
3/10/2010 Since having a hysterectomy (not related to periostat), I've been having some serious digestive issues. Bloating, gas, indigestion; the works. I'm currently taking glutamine and probiotics, but I'm not sure if it's the medicine or not. I was on it for years before this happened, and the package did have warnings about long term use.
1Patient Review
10/24/2008 After having some dental work done, my dentist prescribed this medication. However, I had to stop taking it because it resulted in blood in my stool. I also had to stop taking other medications (simvastatin, baby aspirin and Chantix) until the condition clears up.
Patient Q&A Section about periostat
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long should you use Periostat?
"PERIOSTAT is meant to be used for treatment periods of 3 months. It shouldn't be used for more than 3 consecutive three-month periods. There's no need to change the dosage for elderly patients."
Answered by AI
Is Periostat the same as doxycycline?
"Periostat is a drug used to help reduce pocket depth and promote attachment level gain in patients with adult periodontitis. The dosage of Periostat is different from that of doxycycline, which is used to treat infections."
Answered by AI
What is Periostat used for?
"Periostat is used to treat periodontitis, a condition that affects the gums and can cause teeth to become loose or fall out. The standard treatment for periodontitis is scaling and root planing, which is done by a dentist or dental hygienist."
Answered by AI
What is Periostat periodontics?
"Periostat is an orally administered tablet that contains a novel formulation of 23.08mg doxycycline hyclate. It is designed to be taken twice a day as an adjunct to scaling and root planing (SRP), and has been shown to increase clinical attachment level gain and reduce probing depths in patients with chronic periodontitis."
Answered by AI