Hydroxyzine Pamoate

Neurotic Disorders, Generalized Anxiety Disorder, Itching + 5 more
Treatment
13 FDA approvals
20 Active Studies for Hydroxyzine Pamoate

What is Hydroxyzine Pamoate

HydroxyzineThe Generic name of this drug
Treatment SummaryHydroxyzine is a type of antihistamine that helps reduce symptoms of allergies, such as itching, hives, and rashes. It can also be used to treat anxiety disorders and tension. It was first developed in 1955 and is still commonly used today. The active ingredient in hydroxyzine, cetirizine, is also used in other allergy medications.
Vistarilis the brand name
image of different drug pills on a surface
Hydroxyzine Pamoate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vistaril
Hydroxyzine
1957
585

Approved as Treatment by the FDA

Hydroxyzine, also known as Vistaril, is approved by the FDA for 13 uses which include Nausea and Generalized Anxiety Disorder .
Nausea
Generalized Anxiety Disorder
Neurotic Disorders
Nausea and vomiting
Nausea and Vomiting of Pregnancy
Pruritus
Allergic Conditions
Surgical and medical procedures
Nausea
Itching
Hypersensitivity
Neurotic Disorders
histamine

Effectiveness

How Hydroxyzine Pamoate Affects PatientsHydroxyzine helps reduce symptoms of allergies such as itching, and can also be used as a sedative and anti-nausea medication. It usually starts working within 15-60 minutes and can last for 4-6 hours. It may increase the effects of other medicines that cause drowsiness, so patients should be carefully monitored after receiving general anesthesia. Hydroxyzine can also interfere with the heart's electrical activity, which can lead to serious heart problems, so it should be used cautiously in those with an increased risk of such problems.
How Hydroxyzine Pamoate works in the bodyHydroxyzine is a medicine used to treat allergic reactions. It works by blocking the histamine H1 receptor, which is responsible for causing allergic symptoms like itching, sneezing, and watery eyes. Hydroxyzine also has sedative and anti-nausea effects, which are thought to come from blocking other receptors in the body.

When to interrupt dosage

The suggested dosage of Hydroxyzine Pamoate is contingent upon the diagnosed condition, including Allergic Conditions, Neurotic Disorders and Nausea. The amount of dosage is contingent upon the method of delivery highlighted in the following table.
Condition
Dosage
Administration
Generalized Anxiety Disorder
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Itching
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Surgical and medical procedures
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Nausea
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Nausea
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Hypersensitivity
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
Neurotic Disorders
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual
histamine
, 50.0 mg/mL, 10.0 mg/mL, 25.0 mg, 10.0 mg, 50.0 mg, 25.0 mg/mL, 100.0 mg, 5.0 mg/mL
, Intramuscular, Solution, Solution - Intramuscular, Oral, Syrup, Syrup - Oral, Tablet, film coated - Oral, Tablet, film coated, Capsule - Oral, Capsule, Solution - Oral, Tablet, Tablet - Oral, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Suspension - Oral, Suspension, Sublingual, Troche, Troche - Sublingual

Warnings

Hydroxyzine Pamoate Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Hydroxyzine may interact with Pulse Frequency
Cardiac Arrhythmia
Do Not Combine
Pulse Frequency
Do Not Combine
Pregnancy Trimester, First
Do Not Combine
Sudden Cardiac Death
Do Not Combine
Porphyrias
Do Not Combine
Long QT Syndrome
Do Not Combine
Asthma
Do Not Combine
Bradycardia
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Electrolyte imbalance
Do Not Combine
Torsades de Pointes
Do Not Combine
There are 20 known major drug interactions with Hydroxyzine Pamoate.
Common Hydroxyzine Pamoate Drug Interactions
Drug Name
Risk Level
Description
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Hydroxyzine.
Azelastine
Major
Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Hydroxyzine.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Hydroxyzine.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Hydroxyzine.
Hydroxyzine Pamoate Toxicity & Overdose RiskThe lowest toxic dose of hydroxyzine in rats has been found to be 840 mg/kg and 400 mg/kg in mice. Symptoms of overdose include excessive sedation, seizures, confusion, nausea, and vomiting. Treatment involves inducing vomiting and providing general supportive care. Low blood pressure may be treated with intravenous fluids, and caffeine and sodium benzoate can be administered to reduce the effects of CNS depressants. Dialysis is unlikely to help with hydroxyzine overdose.
image of a doctor in a lab doing drug, clinical research

Hydroxyzine Pamoate Novel Uses: Which Conditions Have a Clinical Trial Featuring Hydroxyzine Pamoate?

At present, 229 active clinical trials are being conducted to investigate the potential of Hydroxyzine Pamoate to treat Generalized Anxiety Disorder, Surgical and medical procedures, as well as Itch.
Condition
Clinical Trials
Trial Phases
Generalized Anxiety Disorder
183 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 4, Phase 1, Phase 3
histamine
0 Actively Recruiting
Itching
2 Actively Recruiting
Phase 3, Not Applicable
Nausea
0 Actively Recruiting
Nausea
0 Actively Recruiting
Neurotic Disorders
0 Actively Recruiting
Surgical and medical procedures
0 Actively Recruiting
Hypersensitivity
0 Actively Recruiting

Hydroxyzine Pamoate Reviews: What are patients saying about Hydroxyzine Pamoate?

5Patient Review
12/26/2021
Hydroxyzine Pamoate for Inducing of a Relaxed Easy State
This treatment has been a godsend for my insomnia and anxiety. Taking a low dose of 10mg every 2 weeks seems to be the sweet spot for me in terms of effectiveness. I wish I had found this sooner!
5Patient Review
4/7/2022
Hydroxyzine Pamoate for Anxious
I find that this medication really helps me to fall asleep and stay asleep for a good 6-8 hours. Before taking it, my mind would never stop racing and I had a lot of trouble falling asleep.
5Patient Review
1/2/2018
Hydroxyzine Pamoate for Anxious
This treatment had similar effects to marijuana in terms of calming me down.
5Patient Review
3/7/2021
Hydroxyzine Pamoate for Additional Medication for Calming
This medicine has been a life-saver for me. I take it as an emergency anxiety medicine and also at bedtime. Normally, I experience crippling anxiety attacks when heading to bed. However, while taking this medicine, it calms me down and allows me to fall asleep faster without the rushing thoughts. I was prescribed to take this one to two times daily, and I am on 50MG. Although if you take it late at night you may experience drowsiness in the morning.
5Patient Review
1/2/2018
Hydroxyzine Pamoate for Anxious
This medication had effects similar to marijuana, in that it calmed me down.
5Patient Review
3/7/2021
Hydroxyzine Pamoate for Additional Medication for Calming
This medicine has been a lifesaver for me. I take it as an emergency anxiety medicine and also at bedtime, and it really helps me to calm down and fall asleep faster. I was prescribed to take this one to two times daily, and I'm currently on 50MG. If you take it late at night, you may experience drowsiness in the morning.
5Patient Review
12/26/2021
Hydroxyzine Pamoate for Inducing of a Relaxed Easy State
This treatment helped me a lot with my insomnia. I was taking a low dose of 10mg every two weeks, and it really made a difference. I wish I had started using it sooner.
5Patient Review
4/7/2022
Hydroxyzine Pamoate for Anxious
I have a lot of trouble shutting off my brain when it's time to sleep, but this medication really helps. I can usually get six to eight hours of solid rest after taking just one 25mg pill.
4.7Patient Review
6/28/2021
Hydroxyzine Pamoate for Anxious
This medication has been incredibly helpful for my anxiety. It's helped me to keep things at a manageable level, and I haven't experienced any negative effects that outweigh the positives.
4.7Patient Review
8/23/2017
Hydroxyzine Pamoate for Anxious
When I have anxiety-induced twitches and itches, this is my go-to medication and it always does the trick.
4.7Patient Review
7/22/2021
Hydroxyzine Pamoate for Anxious
Within an hour of taking this, my anxiety symptoms were either completely relieved or at least significantly reduced. It also helped me sleep through the night, which is a huge plus.
4.7Patient Review
7/22/2021
Hydroxyzine Pamoate for Anxious
I found that this treatment quickly (within an hour) reduced or eliminated my anxiety symptoms. It also helped me sleep better and stay asleep throughout the night, which was a huge relief.
4.7Patient Review
8/23/2017
Hydroxyzine Pamoate for Anxious
This treatment is effective for twitches and itches that come as a result of anxiety. I only use it when needed, and it always provides relief. Not sure why people would take this medication for depression or anxiety instead of other options, but if you're just looking for something to stop the itch, this definitely does the trick.
4.7Patient Review
6/28/2021
Hydroxyzine Pamoate for Anxious
Out of all the medications I've tried for anxiety, this one is by far the best. It's non-habit forming and fast acting, with only minor side effects. I would highly recommend it to anyone dealing with anxiety.
4.3Patient Review
10/31/2022
Hydroxyzine Pamoate for Anxious
This medication has been very helpful in managing my anxiety. It's not a perfect solution, but it definitely takes the edge off and allows me to function. I would recommend it for people with mild anxiety disorders.
4.3Patient Review
10/31/2022
Hydroxyzine Pamoate for Anxious
This medication has been very helpful in managing the anxiety I experience from my autism, ADHD, and bipolar disorder. I use it as needed (usually most days of the month) and it definitely makes a difference. It might make some people sleepy, but I'm able to function on it just fine. Overall, would recommend for mild anxiety.
4Patient Review
1/31/2020
Hydroxyzine Pamoate for Anxious
This medication was effective in helping me sleep and keeping my anxiety at bay. I like that I don't have to take it every day, and can just use it as needed.
4Patient Review
1/31/2020
Hydroxyzine Pamoate for Anxious
This medication was really helpful in terms of getting me to sleep and calming me down. I liked that I didn't need to take it every day, but rather only as needed.
3Patient Review
6/19/2017
Hydroxyzine Pamoate for Anxious
This medication is helpful for calming my anxiety attacks, but it sometimes doesn't work if I wait too long to take it. It's also been prescribed to me as-needed, up to twice daily.
3Patient Review
6/19/2017
Hydroxyzine Pamoate for Anxious
This medication usually does the trick in terms of calming me down from anxiety attacks. However, if I wait too long to take it, it becomes less effective. Also, I was prescribed to take it one to two times daily as needed for my anxiety disorder.
2.7Patient Review
12/16/2021
Hydroxyzine Pamoate for Anxious
I was prescribed 25mg as needed of this medication, but it has caused me a great deal of tension and pressure in the back of my head, difficulty concentrating, and anxiety. I only took it for two days because of these episodes, but I've been dealing with the side effects ever since.
2.7Patient Review
12/16/2021
Hydroxyzine Pamoate for Anxious
I was prescribed 25mg of this medication to take as needed, but it has only caused me more anxiety. I took the pill for two days straight and have been dealing with its side effects ever since.
1Patient Review
10/14/2021
Hydroxyzine Pamoate for Inducing of a Relaxed Easy State
I was prescribed this after being taken off of clonazepam, which actually worked for me. This medication does nothing in comparison and the withdrawal from clonazepam has been incredibly difficult. I haven't slept more than an hour or two since stopping that medicine, and my anxiety is through the roof. Doctors are quick to prescribe this as a replacement for something that actually works because they're afraid of addiction, but all this has done is make me miserable.
1Patient Review
5/1/2018
Hydroxyzine Pamoate for Inflammation of Skin caused by an Allergy
Unfortunately, this medication did not help me with either my allergies or anxiety.
1Patient Review
5/1/2018
Hydroxyzine Pamoate for Inflammation of Skin caused by an Allergy
This treatment did nothing to help my allergies or anxiety.
1Patient Review
10/14/2021
Hydroxyzine Pamoate for Inducing of a Relaxed Easy State
I was really struggling after being taken off of clonazepam. This medication did nothing to help me with my anxiety or insomnia. It's been brutal trying to withdraw. I don't understand why doctors are so afraid of addiction when this has been such a nightmare.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about hydroxyzine pamoate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is hydroxyzine pamoate used for?

"Hydroxyzine is used to treat itching resulting from allergies. By blocking histamine, it functions as an antihistamine to alleviate allergic reactions."

Answered by AI

Is hydroxyzine pamoate the same as Xanax?

"These drugs work by different mechanisms, but both have anti-anxiety effects.

The drugs Vistaril and Xanax are both used to treat anxiety, though they work via different mechanisms. Vistaril is an antihistamine with drying and sedative properties, while Xanax is a benzodiazepine. Though their means of anxious relief differ, both drugs are effective."

Answered by AI

Is hydroxyzine pamoate good for anxiety?

"Vistaril is used as a short-term treatment for anxiety symptoms or as an alternative to habit-forming anxiety medications such as benzodiazepines. It is also prescribed as an antihistamine to treat skin allergies, so it can be a good choice for people who have both allergies and anxiety."

Answered by AI

Is hydroxyzine pamoate a sleeping pill?

"Hydroxyzine is an antihistamine that is approved for the treatment of anxiety. However, it is also used to treat difficulty sleeping, nausea, vomiting, itching, skin rash, and allergies."

Answered by AI

Clinical Trials for Hydroxyzine Pamoate

Image of Cedars-Sinai Medical Center in Los Angeles, United States.

Living Well Program for Anxiety in Breast Cancer

18+
Female
Los Angeles, CA
The goal of this study is to evaluate the efficacy and cost-effectiveness of the Living Well Program, a digital therapeutic application with telecoaching support, in breast cancer patients with moderate-to-severe anxiety. The main question the study aims to answer is: does digital cognitive-behavioral therapy-based interventions decrease the overall healthcare costs of patients with stage II to IV breast cancer? The study has one group of participants who will use the Living Well app and telecoaching support. This group will be compared to retroactively matched controls. Over 3 months, patients will complete 21 mental health modules and 5 telecoaching sessions. In the following 3 months, they will complete any outstanding telecoaching sessions and modules while still being monitored, even if they finished all modules and sessions in the first 3 months. The 6 months after that will be the follow-up phase. They will still have access to the Living Well app and may continue to use it, and they will complete the same assessment questionnaires as baseline to identify any changes in their overall mental health.
Waitlist Available
Has No Placebo
Cedars-Sinai Medical CenterScott Irwin, MD
Image of Virtual/ No Physical Facility in Palm City, United States.

Akashic Records Sessions for Mental Health

18+
All Sexes
Palm City, FL
The goal of this clinical study is to learn the impact of two Akashic Records sessions on mental health symptoms in adults. We want to see how sessions are linked to stress, anxiety, and depression, and to resilience (ability to bounce back) and feelings of connectedness (to self, community, and humanity). Main questions this study will answer are: After two sessions, what is the impact on stress, anxiety, and depression? After two sessions, what is the impact on resilience and connectedness? How do participants describe their experience of the sessions? After two sessions, what are participants' views of their problems (insight), emotional experiences (impact) and observable behaviors in their daily life? What participants will do: Complete online surveys about their mood at four points: before the first session, before the second session, after the second session, and again 2 months later. Surveys include: DASS-21 (Depression, Anxiety, and Stress Scale) CD-RISC-10 (Connor-Davidson Resilience Scale) WATTS (Connectedness Scale) A short demographic form and satisfaction survey Attend two individual Akashic Records sessions (50-90 minutes each) over private video platform with a licensed clinical social worker (principal investigator) The first 50 participants will also join a one-hour interview with open ended questions with a licensed clinical social worker (co-investigator) about one week after the second session to share their experience in their own words. Who can take part: Adults ages 18 and older who can read and consent in English and who have experienced stress, anxiety, or low mood in the past year. How the research will happen: Sessions are held by secure video call. Participants will also complete private online surveys before, during, and after the sessions. Some participants may be invited to share their experiences in a one-on-one interview. All information is kept private and names are removed before analysis. Risks and benefits: Talking about personal topics may bring up strong emotions. Licensed clinicians conduct sessions, offer support, and provide referrals if needed. Possible benefits include new insights, greater peace or meaning, and improved coping; benefits are not guaranteed. Why this matters: Many people seek spiritual or transpersonal support for emotional concerns. This pilot study will provide early evidence on whether Akashic Records sessions may be a helpful, low-risk option and will guide future research.
Waitlist Available
Has No Placebo
Virtual/ No Physical FacilityCandice S Rasa, LCSW
Have you considered Hydroxyzine Pamoate clinical trials? We made a collection of clinical trials featuring Hydroxyzine Pamoate, we think they might fit your search criteria.Go to Trials
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Safe and Sound Protocol for Substance Abuse

18 - 75
All Sexes
Wernersville, PA
This study will explore whether the use of the Safe and Sound Protocol (SSP) app is an effective adjunct to treatment as usual (TAU) in individuals with co-occurring substance use disorders and trauma. This study will recruit 129 participants (100 completers) randomized to receive either active or sham SSP in addition to TAU. Participants will utilize the SSP for a minimum of three hours to a maximum of five hours for a total of seven days. Data will be collected at both pre- and post-test. Data to be collected will include measures on affect, anxiety, personality, mindfulness, and posttraumatic stress disorder symptoms. The SSP has shown effectiveness in reducing symptoms of anxiety, depression, and trauma symptoms in pilot studies conducted at other locations. This will be the first study to examine the effectiveness of SSP with individuals with co-occurring SUD and trauma.
Waitlist Available
Device
Caron Treatment CentersErin Deneke, PhD
Image of Cresap Laboratory in Evanston, United States.

Dream Yoga Inspired Intervention for Anxiety

18+
All Sexes
Evanston, IL
This is a feasibility study to test whether it is possible to deliver a program inspired by Tibetan Dream Yoga in a modern, accessible way. Dream Yoga is a set of contemplative practices that combine mental exercises during the day with techniques for becoming aware of dreaming within a dream (lucid dreaming) and engage in certain dream activities. The purpose of these practices is to help people explore and loosen rigid patterns of thought and behavior. In this study, the investigators are developing and testing a program that includes guided imagination, meditation, and lucid-dreaming practices, supported by virtual-reality experiences and home-based sleep-monitoring technology. Participants are randomly assigned to either the Dream-Yoga-inspired program or a comparison program focused on general health and sleep education. Because this is a feasibility trial, our main goals are to see whether people are willing and able to take part, whether they find the program acceptable, and whether the investigators can deliver it as planned. The investigators will also explore early signals of change in sleep, dreaming, and thinking. The long-term goal of this research is to determine if such interventions could be beneficial for supporting psychological well-being, improving sleep, and enhancing creativity and flexibility of thought.
Phase < 1
Waitlist Available
Cresap Laboratory (+1 Sites)
Image of Center for Technology and Behavioral Health (CTBH), Geisel School of Medicine at Dartmouth College in Lebanon, United States.

Advertising Claims for Anxiety and Depression

18+
All Sexes
Lebanon, NH
In the U.S., legal cannabis is frequently advertised as an effective treatment for mental health problems such as anxiety and depression-particularly online. States that have legalized cannabis have not implemented regulations to address this type of advertising. This project aims to investigate the influence of psychotherapeutic advertising claims (PAC) and mental health warning labels (WL) on online cannabis purchasing behaviors among light-to-moderate cannabis users with symptoms of depression and/or anxiety. The specific aims are to determine whether PAC increases cannabis purchasing intentions and whether a mental health WL can mitigate this effect. A realistic online cannabis shopping experience will be simulated using the digital Platform for Online Evaluation of Marijuana Marketing and Sales (POEMMS). The study will employ a between-subjects experimental design by randomizing 2,000 participants to one of four online stores that vary in PAC and WL content: (1) a control claims (CC)-only store, (2) a PAC store, (3) a WL store, and (4) a PAC + WL store. Participants will browse and select items as if making real purchases. Analyses will examine three primary outcomes to determine the influence of PAC and WL on purchasing behaviors: (1) total milligrams of THC purchased, (2) average potency (%THC) of products, and (3) overall number of products purchased. The long-term objective is to inform evidence-based cannabis policy and regulatory strategies by understanding the impact of cannabis marketing on vulnerable populations. This research is relevant to public health by addressing the potential risks associated with misleading cannabis marketing, which may lead to increased use and exacerbation of mental health symptoms among individuals with depression and anxiety. The project leverages a multidisciplinary team with expertise in addiction, mental health, epidemiology, and digital health technology. The findings have the potential to inform the development of targeted interventions and policies to reduce harms associated with cannabis advertising-ultimately contributing to better health outcomes and more effective regulation.
Waitlist Available
Has No Placebo
Center for Technology and Behavioral Health (CTBH), Geisel School of Medicine at Dartmouth CollegeJennifer Emond, PHD
Image of Florida International University in Miami, United States.

Biofeedback for Anxiety

18 - 35
All Sexes
Miami, FL
This study aims to evaluate the effectiveness of a four-week heart rate variability (HRV) biofeedback intervention to improve physiological stress response, emotion regulation, and anxiety-related symptoms in young ethnic minority adults with a family history of cardiovascular disease (CVD). Participants will be randomly assigned to either an intervention group, where they will engage in guided paced breathing exercises, or a control group, which will follow standard conditions without the intervention. The study consists of five sessions, including an initial assessment, three weekly check-in sessions, and a final post-intervention assessment. Participants will practice paced breathing at home and attend brief in-lab sessions to track progress. Physiological and psychological measures, such as HRV, GSR, BP, anxiety levels, and responses to the Socially Evaluated Cold Pressor Test (SECPT), will be used to assess outcomes. Findings from this study may provide insights into accessible, non-invasive stress management interventions to mitigate CVD risk in high-risk populations.
Recruiting
Has No Placebo
Florida International UniversityAmelia D Saul, PhD
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Digital Physical Activity for Depression

19 - 40
All Sexes
Auburn, AL
The present study will assess the effects of a four-week digitally delivered intervention on physical activity and depressive symptoms among adults experiencing at least moderate depressive symptoms. The main questions this research aims to answer are: * Does a digitally-delivered intervention increase physical activity levels? * Does a digitally-delivered intervention reduce symptoms of depression? Researchers will compare an intervention promoting physical activity to a passive control (does not receive the intervention) group to see if the intervention reduces depressive symptoms and increases physical activity levels. Participants will: * Visit the laboratory at two separate time points before group assignment, separated by one week of physical activity monitoring * Be randomly assigned to complete four weeks of a digital intervention prompting engagement in physical activity or have their mental health symptoms monitored over four weeks (i.e., passive control group) * Visit the laboratory at two separate time points after the intervention, separated by one week of physical activity monitoring
Recruiting
Has No Placebo
Kinesiology Building
Have you considered Hydroxyzine Pamoate clinical trials? We made a collection of clinical trials featuring Hydroxyzine Pamoate, we think they might fit your search criteria.Go to Trials
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