Venlafaxine Hydrochloride

Migraine, Panic Disorder, Migraine Disorders + 7 more
Treatment
5 FDA approvals
20 Active Studies for Venlafaxine Hydrochloride

What is Venlafaxine Hydrochloride

VenlafaxineThe Generic name of this drug
Treatment SummaryVenlafaxine (Effexor) is a type of antidepressant medication called a serotonin-norepinephrine reuptake inhibitor. It works by blocking the transporters responsible for reabsorbing serotonin and norepinephrine, leaving more of the neurotransmitters available in the brain. Venlafaxine is approved to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, and panic disorder. It can also be used to prevent migraine headaches, reduce menopause symptoms, and manage neuropathic pain, although there is limited evidence that it is effective for this condition.
Effexoris the brand name
image of different drug pills on a surface
Venlafaxine Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Effexor
Venlafaxine
1993
725

Approved as Treatment by the FDA

Venlafaxine, also known as Effexor, is approved by the FDA for 5 uses such as Hot Flashes and Breast Cancer .
Hot Flashes
Helps manage Vasomotor Symptoms Associated With Menopause
Breast Cancer
Helps manage Breast Cancer
Depression
Breast Cancer
Helps manage Breast Cancer
Vasomotor Symptoms Associated With Menopause
Helps manage Vasomotor Symptoms Associated With Menopause

Effectiveness

How Venlafaxine Hydrochloride Affects PatientsVenlafaxine is a medication used to treat depression and other mental disorders. It works by increasing the amount of certain chemicals in the brain that are responsible for mood regulation. Venlafaxine does not cause any additional effects on the body's other systems.
How Venlafaxine Hydrochloride works in the bodyVenlafaxine is used to treat various mental health conditions. It works by increasing the amount of serotonin and norepinephrine at the synapse, which are the gaps between nerve cells. It does this by blocking the reuptake, or recycling, of these neurotransmitters. It primarily affects serotonin, but can also affect norepinephrine and dopamine with higher doses.

When to interrupt dosage

The measure of Venlafaxine Hydrochloride is contingent upon the diagnosed ailment, including Social Anxiety Disorder, Neuropathic Pain and Vasomotor Symptoms Associated With Menopause. The quantity of dosage is contingent upon the method of delivery (e.g. Tablet or Tablet - Oral) noted in the table beneath.
Condition
Dosage
Administration
Panic Disorder
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Migraine Disorders
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Breast Cancer
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Postmenopause
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Depression
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Hot Flashes
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Migraine
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Generalized Anxiety Disorder
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Social Anxiety Disorder
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral
Neuropathic Pain
, 75.0 mg, 150.0 mg, 37.5 mg, 25.0 mg, 50.0 mg, 100.0 mg, 225.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet - Oral, Tablet, Tablet, extended release, Tablet, extended release - Oral, Capsule, delayed release, Capsule, delayed release - Oral, Capsule, coated, extended release, Capsule, coated, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

Venlafaxine Hydrochloride Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Venlafaxine may interact with Pulse Frequency
There are 20 known major drug interactions with Venlafaxine Hydrochloride.
Common Venlafaxine Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Venlafaxine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Venlafaxine is combined with Hydroxyzine.
Iobenguane
Major
The therapeutic efficacy of Iobenguane can be decreased when used in combination with Venlafaxine.
Methylene blue
Major
Venlafaxine may increase the serotonergic activities of Methylene blue.
Venlafaxine Hydrochloride Toxicity & Overdose RiskThe lowest toxic dose of venlafaxine in rats was 350 mg/kg for female rats and 700 mg/kg for male rats. Those who overdose on venlafaxine may feel sleepy, experience numbness or tingling in the extremities, dizziness, confusion, nausea, vomiting, low blood pressure, seizures, irregular heartbeat, liver damage, and even death. There is no known remedy for venlafaxine overdose, and symptoms may be managed without or with treatment, hospitalization, and activated charcoal. Studies have also shown that the risk of fatal outcomes from venlafaxine overdose is higher
image of a doctor in a lab doing drug, clinical research

Venlafaxine Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Venlafaxine Hydrochloride?

Currently, 1038 studies are being conducted to explore the potential of Venlafaxine Hydrochloride for the management of Neuropathic Pain, prophylaxis of migraine headaches and Vasomotor Symptoms Associated With Menopause.
Condition
Clinical Trials
Trial Phases
Depression
195 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 1, Early Phase 1, Phase 3
Panic Disorder
9 Actively Recruiting
Not Applicable
Postmenopause
8 Actively Recruiting
Phase 2, Not Applicable, Phase 1
Neuropathic Pain
5 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Migraine
54 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Breast Cancer
26 Actively Recruiting
Phase 2, Phase 1, Not Applicable
Migraine Disorders
1 Actively Recruiting
Phase 3
Social Anxiety Disorder
21 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Hot Flashes
1 Actively Recruiting
Not Applicable
Generalized Anxiety Disorder
4 Actively Recruiting
Not Applicable, Phase 2

Venlafaxine Hydrochloride Reviews: What are patients saying about Venlafaxine Hydrochloride?

5Patient Review
8/10/2022
Venlafaxine Hydrochloride for "Change of Life" Signs
Venlafaxine has been an absolute godsend. I was experiencing hot flashes every fifteen minutes--to the point where it was disrupting my work life-- and this medication has helped to completely alleviate that problem. It's also helped with some of my anxiety symptoms, which is a huge plus. I'm very grateful to have found this medication!
5Patient Review
8/26/2022
Venlafaxine Hydrochloride for Depression
I've only been on this for a day, but I already feel so much better. For the first time in a long time, I didn't have any negative thoughts or feelings throughout the day. It's truly a godsend.
5Patient Review
9/18/2022
Venlafaxine Hydrochloride for Repeated Episodes of Anxiety
This drug has been working great for me in terms of managing my anger.
3.7Patient Review
8/13/2022
Venlafaxine Hydrochloride for Depression
I'm only on my second week taking this medication, and I am already experiencing a lot of the listed side effects. I'm hoping that they will go away soon. Does anyone have any suggestions?
1.7Patient Review
6/27/2022
Venlafaxine Hydrochloride for Panic Disorder
Terrible, I was out of it everyday and still having panic attacks
View All Reviews
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Patient Q&A Section about venlafaxine hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is venlafaxine hydrochloride used for?

"Venlafaxine is a medication used to treat depression, anxiety disorders, and panic disorders. Venlafaxine is part of a class of drugs called serotonin and norepinephrine reuptake inhibitors (SNRIs)."

Answered by AI

Is venlafaxine a strong antidepressant?

"The doctor may prescribe Effexor for other conditions besides the standard ones it is meant for. One study found that it was an effective antidepressant. However, each person's reaction and tolerance to the medicine may be different."

Answered by AI

Is venlafaxine same as Xanax?

"Effexor XR is a serotonin and norepinephrine reuptake inhibitor (SNRI) and Xanax is a benzodiazepine.

Do Effexor XR and Xanax serve the same purpose? Effexor XR (venlafaxine hydrochloride extended-release) and Xanax (alprazolam) are both used to treat patients with panic and anxiety disorders. Effexor XR is also used to treat patients with major depressive disorders. However, Effexor XR and Xanax belong to different drug classes. Effexor XR is a serotonin and norepinephrine reuptake inhibitor (SNRI) while Xanax is a benzodiazepine."

Answered by AI

What are the side effects of venlafaxine hydrochloride?

"... , Sickness (vomiting)

If you are feeling nauseous, try taking venlafaxine with or after a meal. To help with sweating and hot flushes, wear loose clothing and use a fan where possible. If you are having headaches, rest and drink plenty of fluids. A dry mouth is another common side effect. If you are feeling dizzy or sleepy, try to lie down and relax. Some people also have trouble sleeping when taking this medication. Constipation is another possible side effect. Lastly, some people may vomit."

Answered by AI

Clinical Trials for Venlafaxine Hydrochloride

Have you considered Venlafaxine Hydrochloride clinical trials? We made a collection of clinical trials featuring Venlafaxine Hydrochloride, we think they might fit your search criteria.
Have you considered Venlafaxine Hydrochloride clinical trials? We made a collection of clinical trials featuring Venlafaxine Hydrochloride, we think they might fit your search criteria.
Have you considered Venlafaxine Hydrochloride clinical trials? We made a collection of clinical trials featuring Venlafaxine Hydrochloride, we think they might fit your search criteria.
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