Escitalopram Oxalate

Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Depression
Treatment
20 Active Studies for Escitalopram Oxalate

What is Escitalopram Oxalate

EscitalopramThe Generic name of this drug
Treatment SummaryEscitalopram is an antidepressant medication used to treat depression and anxiety. It works by increasing the amount of the chemical serotonin in the brain. It is more potent and effective than citalopram, its parent drug. Escitalopram is also known to have fewer side effects than other drugs in its class. It works faster than other antidepressants and has a higher degree of selectivity for the serotonin transporter, which may explain its superior efficacy.
Lexaprois the brand name
image of different drug pills on a surface
Escitalopram Oxalate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lexapro
Escitalopram
2002
362

Effectiveness

How Escitalopram Oxalate Affects PatientsEscitalopram is a type of medicine called a selective serotonin re-uptake inhibitor (SSRI). It works by increasing the amount of serotonin in the brain and can help treat certain mental health conditions. Though it is considered to be effective faster than other SSRIs, there is still a risk of abnormal bleeding and serotonin syndrome if taken with other medications that affect the body's ability to stop bleeding. If you need to stop taking escitalopram, make sure to do it slowly over time.
How Escitalopram Oxalate works in the bodyEscitalopram works by blocking the re-uptake of serotonin in the brain. This increases the amount of serotonin available in the brain, which helps reduce symptoms of depression. It does this by binding to a special site on the serotonin transporter called the orthosteric binding site. It also binds to a secondary site called an allosteric site, making it more effective than other selective serotonin re-uptake inhibitors. Long-term use of escitalopram will desensitize serotonin receptors, allowing for a longer-lasting effect. Escitalopram does not bind to many other receptors and any minor activity may lead to

When to interrupt dosage

The suggested measure of Escitalopram Oxalate is contingent upon the diagnosed condition, including Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression. The quantity of dosage is reliant upon the method of delivery as shown in the table beneath.
Condition
Dosage
Administration
Obsessive-Compulsive Disorder
20.0 mg, , 10.0 mg, 5.0 mg, 5.0 mg/mL, 15.0 mg, 1.0 mg, 2.0 mg, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Solution - Oral, Kit, Solution, Tablet, coated
Generalized Anxiety Disorder
20.0 mg, , 10.0 mg, 5.0 mg, 5.0 mg/mL, 15.0 mg, 1.0 mg, 2.0 mg, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Solution - Oral, Kit, Solution, Tablet, coated
Depression
20.0 mg, , 10.0 mg, 5.0 mg, 5.0 mg/mL, 15.0 mg, 1.0 mg, 2.0 mg, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Solution - Oral, Kit, Solution, Tablet, coated

Warnings

Escitalopram Oxalate has five contraindications and should not be administered concurrently with the circumstances mentioned in the following table.Escitalopram Oxalate Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Escitalopram may interact with Pulse Frequency
Long QT Syndrome
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Long QT Syndrome
Do Not Combine
There are 20 known major drug interactions with Escitalopram Oxalate.
Common Escitalopram Oxalate Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Aclidinium.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Escitalopram is combined with Artemether.
Azelastine
Major
Escitalopram may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Cimetropium.
Dronedarone
Major
Escitalopram may increase the QTc-prolonging activities of Dronedarone.
Escitalopram Oxalate Toxicity & Overdose RiskPeople who overdose on escitalopram may experience dizziness, seizures, extreme drowsiness, nausea, vomiting, low blood pressure, rapid heart rate, and changes to the heart rhythm. There is no known antidote for escitalopram overdose, so treatment should focus on monitoring vital signs and providing supportive care as needed. Since escitalopram is absorbed into the body's tissues, methods such as forced diuresis, dialysis, and other treatments to remove the drug from the bloodstream are unlikely to be helpful.
image of a doctor in a lab doing drug, clinical research

Escitalopram Oxalate Novel Uses: Which Conditions Have a Clinical Trial Featuring Escitalopram Oxalate?

231 active clinical trials are examining the potential of Escitalopram Oxalate to provide relief from Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression.
Condition
Clinical Trials
Trial Phases
Depression
213 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1, Early Phase 1
Generalized Anxiety Disorder
7 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Obsessive-Compulsive Disorder
67 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1

Escitalopram Oxalate Reviews: What are patients saying about Escitalopram Oxalate?

5Patient Review
9/23/2022
Escitalopram Oxalate for Depression
I'm very pleased with how this medication has been working for me. I was struggling with anxiety and depression, but now I'm doing much better. It's important to start slowly with a lower dosage and increase as needed; results won't be immediate, so give it at least 2-3 weeks before you make any decisions!
5Patient Review
2/9/2022
Escitalopram Oxalate for Depression
After my husband died a year ago, I was able to cope for the first few months. However, as events and anniversaries came up, I became more depressed. My doctor recommended Lexapro and started me on a 5mg daily dose. I have had no side effects and can now deal with day-to-day living much better. I've actually gained 10 pounds over the past year--which is something of a relief because I lost 15 pounds in the two months after he passed away from barely eating anything.
4.3Patient Review
8/13/2022
Escitalopram Oxalate for Posttraumatic Stress Syndrome
I've been on this medication for three months. It's made me very horny and up for sex all the time, which can be great, but also a little overwhelming. I'm not sure if I should keep taking it or not.
4.3Patient Review
6/8/2022
Escitalopram Oxalate for Depression
As a student, I find this medicine incredibly helpful in managing stress and anxiety. Sometimes I do take more than recommended, but it always helps me out.
4Patient Review
4/19/2022
Escitalopram Oxalate for Depression
This treatment helps me stay level-headed and in a good space.
3.3Patient Review
8/9/2022
Escitalopram Oxalate for Anxiousness associated with Depression
Withdrawal from this drug can be difficult and doctors should be consulted before quitting.
3Patient Review
8/26/2022
Escitalopram Oxalate for Anxiousness associated with Depression
I swapped to this treatment about two years ago and it helped decrease my panic attacks from 20mg to 10mg. However, I recently stopped taking the medication entirely and today experienced a terrible withdrawal attack. Please don't make the same mistake I did- speak with your GP before making any changes to your dosage.
3Patient Review
6/30/2022
Escitalopram Oxalate for Depression
I've been taking this medication on and off for a few years now to help with anxiety and depression. I love how well it works, but if I miss even a dose, I have severe withdrawal symptoms like migraines and nausea.
2.7Patient Review
11/13/2022
Escitalopram Oxalate for Depression
I've been taking this medicine for almost three weeks now and I'm experiencing more panic attacks and worse headaches than before. It was hard to sleep at first, but now I'm feeling sleepy all day long.
2.7Patient Review
2/14/2022
Escitalopram Oxalate for Depression
I've been on this medication for a month now and my anxiety has only gotten worse. My doctor wants me to give it two more weeks, but I don't know if I can handle it.
2Patient Review
4/23/2022
Escitalopram Oxalate for Posttraumatic Stress Syndrome
I have issues with bad panic attacks, so I'm always looking for treatments that can help. Unfortunately, this isn't one of them. It's made my asthma worse and I feel constantly bloated and anxious. I've tried it twice now and hated it both times.
2Patient Review
1/31/2022
Escitalopram Oxalate for Depression
I had some serious emotional ups and downs, as well as digestive problems, while taking this medication. Unfortunately, it was also ineffective in treating my condition.
1Patient Review
6/21/2022
Escitalopram Oxalate for Depression
I would not recommend this medication to anyone. I experienced a whole host of negative side effects, including nausea, weakness, and loss of appetite. This medicine made my condition worse instead of better.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about escitalopram oxalate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is escitalopram a form of Xanax?

"While both drugs may cause some of the same side effects, they are in different drug classes. Lexapro is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine."

Answered by AI

Is Lexapro escitalopram oxalate?

"The drug Lexapro is available in either tablet or liquid form. The tablets come in three different strengths (5mg, 10mg, 20mg) and are round with a film coating. The 10 and 20mg tablets are also scored so they can be easily broken in half if needed."

Answered by AI

Clinical Trials for Escitalopram Oxalate

Image of St. Joseph's Healthcare Hamilton in Hamilton, Canada.

Psychotherapy for Depression

18 - 65
Female
Hamilton, Canada
The RESPOND trial explores the link between early life adversity and later life depressive symptoms. The investigators have designed a new psychological therapy tailored to address the symptoms that can be caused by difficult experiences in early life. These symptoms include low mood, emotional dysregulation, and distressing thoughts and beliefs related to difficult or traumatic experiences. The investigators would like to see if this new therapy helps people feel better. The investigators are also studying the biological changes that can occur as a result of early life adversity, and how this therapy may influence those changes. To do this, The investigators ask questions about participants' physical and mental health and take blood samples.
Recruiting
Has No Placebo
St. Joseph's Healthcare HamiltonSheryl Green, PhD
Image of Baylor College of Medicine in Houston, United States.

Stepped Care Treatment for Anxiety

7 - 17
All Sexes
Houston, TX
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD. Yet, many children do not receive care due to barriers such as limited provider availably, high treatment costs, and constrained family resources (e.g., time). To combat these barriers, other treatment methods have been developed. The stepped care treatment models maximize resources by providing low-intensity, low-cost interventions as a first time treatment, while stepping up care for those needing more intensive treatment. Specifically, a stepped care model for CAD that begins with a parent-focus intervention has great promise to deliver efficacious and cost-effective treatment without having to engage the child. While stepped care approaches show promise in treating CAD with comparable efficacy to standard CBT, there remains a large research-to-practice gap. The stepped care model for CAD that begins with a parent-focused intervention has yet been explored, and very little is known about intervention mediators that explain mechanisms of change. This research is being done to improve the reach and quality of services using a stepped care model, offering an affordable and practical solution to the widespread gap in youth mental health care.
Waitlist Available
Has No Placebo
Baylor College of Medicine
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.Go to Trials
Image of Detroit Recovery Project in Detroit, United States.

Peer-Delivered Behavioral Activation for Depression

18+
All Sexes
Detroit, MI
Low-income individuals have limited access to evidence-based interventions for mental health. Peer recovery specialists, individuals in recovery from mental health and/or substance use problems, have the potential to increase access to evidence-based interventions for individuals from low-resource communities, particularly when trained and supervised in models that are acceptable and feasible in these communities. This study will examine the effectiveness and implementation potential of a peer-delivered evidence-based intervention (Behavioral Activation) among individuals receiving services from a community-based treatment setting providing integrated physical and behavioral healthcare.
Waitlist Available
Has No Placebo
Detroit Recovery Project
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.Go to Trials
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.Go to Trials
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