Escitalopram Oxalate

Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Depression
Treatment
20 Active Studies for Escitalopram Oxalate

What is Escitalopram Oxalate

EscitalopramThe Generic name of this drug
Treatment SummaryEscitalopram is an antidepressant medication used to treat depression and anxiety. It works by increasing the amount of the chemical serotonin in the brain. It is more potent and effective than citalopram, its parent drug. Escitalopram is also known to have fewer side effects than other drugs in its class. It works faster than other antidepressants and has a higher degree of selectivity for the serotonin transporter, which may explain its superior efficacy.
Lexaprois the brand name
Escitalopram Oxalate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lexapro
Escitalopram
2002
348

Effectiveness

How Escitalopram Oxalate Affects PatientsEscitalopram is a type of medicine called a selective serotonin re-uptake inhibitor (SSRI). It works by increasing the amount of serotonin in the brain and can help treat certain mental health conditions. Though it is considered to be effective faster than other SSRIs, there is still a risk of abnormal bleeding and serotonin syndrome if taken with other medications that affect the body's ability to stop bleeding. If you need to stop taking escitalopram, make sure to do it slowly over time.
How Escitalopram Oxalate works in the bodyEscitalopram works by blocking the re-uptake of serotonin in the brain. This increases the amount of serotonin available in the brain, which helps reduce symptoms of depression. It does this by binding to a special site on the serotonin transporter called the orthosteric binding site. It also binds to a secondary site called an allosteric site, making it more effective than other selective serotonin re-uptake inhibitors. Long-term use of escitalopram will desensitize serotonin receptors, allowing for a longer-lasting effect. Escitalopram does not bind to many other receptors and any minor activity may lead to

When to interrupt dosage

The suggested measure of Escitalopram Oxalate is contingent upon the diagnosed condition, including Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression. The quantity of dosage is reliant upon the method of delivery as shown in the table beneath.
Condition
Dosage
Administration
Generalized Anxiety Disorder
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated
Obsessive-Compulsive Disorder
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated
Depression
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated

Warnings

Escitalopram Oxalate has five contraindications and should not be administered concurrently with the circumstances mentioned in the following table.Escitalopram Oxalate Contraindications
Condition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Long QT Syndrome
Do Not Combine
Toxoplasma Infections
Do Not Combine
Prolonged QT Interval
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Escitalopram may interact with Toxoplasma Infections
There are 20 known major drug interactions with Escitalopram Oxalate.
Common Escitalopram Oxalate Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Aclidinium.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Escitalopram is combined with Artemether.
Azelastine
Major
Escitalopram may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Cimetropium.
Dronedarone
Major
Escitalopram may increase the QTc-prolonging activities of Dronedarone.
Escitalopram Oxalate Toxicity & Overdose RiskPeople who overdose on escitalopram may experience dizziness, seizures, extreme drowsiness, nausea, vomiting, low blood pressure, rapid heart rate, and changes to the heart rhythm. There is no known antidote for escitalopram overdose, so treatment should focus on monitoring vital signs and providing supportive care as needed. Since escitalopram is absorbed into the body's tissues, methods such as forced diuresis, dialysis, and other treatments to remove the drug from the bloodstream are unlikely to be helpful.

Escitalopram Oxalate Novel Uses: Which Conditions Have a Clinical Trial Featuring Escitalopram Oxalate?

231 active clinical trials are examining the potential of Escitalopram Oxalate to provide relief from Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression.
Condition
Clinical Trials
Trial Phases
Obsessive-Compulsive Disorder
15 Actively Recruiting
Not Applicable, Phase 3
Generalized Anxiety Disorder
34 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 1
Depression
200 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Phase 4, Early Phase 1

Escitalopram Oxalate Reviews: What are patients saying about Escitalopram Oxalate?

5Patient Review
9/23/2022
Escitalopram Oxalate for Depression
I'm very pleased with how this medication has been working for me. I was struggling with anxiety and depression, but now I'm doing much better. It's important to start slowly with a lower dosage and increase as needed; results won't be immediate, so give it at least 2-3 weeks before you make any decisions!
5Patient Review
2/9/2022
Escitalopram Oxalate for Depression
After my husband died a year ago, I was able to cope for the first few months. However, as events and anniversaries came up, I became more depressed. My doctor recommended Lexapro and started me on a 5mg daily dose. I have had no side effects and can now deal with day-to-day living much better. I've actually gained 10 pounds over the past year--which is something of a relief because I lost 15 pounds in the two months after he passed away from barely eating anything.
4.3Patient Review
8/13/2022
Escitalopram Oxalate for Posttraumatic Stress Syndrome
I've been on this medication for three months. It's made me very horny and up for sex all the time, which can be great, but also a little overwhelming. I'm not sure if I should keep taking it or not.
4.3Patient Review
6/8/2022
Escitalopram Oxalate for Depression
As a student, I find this medicine incredibly helpful in managing stress and anxiety. Sometimes I do take more than recommended, but it always helps me out.
4Patient Review
4/19/2022
Escitalopram Oxalate for Depression
This treatment helps me stay level-headed and in a good space.
3.3Patient Review
8/9/2022
Escitalopram Oxalate for Anxiousness associated with Depression
Withdrawal from this drug can be difficult and doctors should be consulted before quitting.
3Patient Review
8/26/2022
Escitalopram Oxalate for Anxiousness associated with Depression
I swapped to this treatment about two years ago and it helped decrease my panic attacks from 20mg to 10mg. However, I recently stopped taking the medication entirely and today experienced a terrible withdrawal attack. Please don't make the same mistake I did- speak with your GP before making any changes to your dosage.
3Patient Review
6/30/2022
Escitalopram Oxalate for Depression
I've been taking this medication on and off for a few years now to help with anxiety and depression. I love how well it works, but if I miss even a dose, I have severe withdrawal symptoms like migraines and nausea.
2.7Patient Review
11/13/2022
Escitalopram Oxalate for Depression
I've been taking this medicine for almost three weeks now and I'm experiencing more panic attacks and worse headaches than before. It was hard to sleep at first, but now I'm feeling sleepy all day long.
2.7Patient Review
2/14/2022
Escitalopram Oxalate for Depression
I've been on this medication for a month now and my anxiety has only gotten worse. My doctor wants me to give it two more weeks, but I don't know if I can handle it.
2Patient Review
4/23/2022
Escitalopram Oxalate for Posttraumatic Stress Syndrome
I have issues with bad panic attacks, so I'm always looking for treatments that can help. Unfortunately, this isn't one of them. It's made my asthma worse and I feel constantly bloated and anxious. I've tried it twice now and hated it both times.
2Patient Review
1/31/2022
Escitalopram Oxalate for Depression
I had some serious emotional ups and downs, as well as digestive problems, while taking this medication. Unfortunately, it was also ineffective in treating my condition.
1Patient Review
6/21/2022
Escitalopram Oxalate for Depression
I would not recommend this medication to anyone. I experienced a whole host of negative side effects, including nausea, weakness, and loss of appetite. This medicine made my condition worse instead of better.

Patient Q&A Section about escitalopram oxalate

Is escitalopram a form of Xanax?

"While both drugs may cause some of the same side effects, they are in different drug classes. Lexapro is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine." - Anonymous Online Contributor

Unverified Answer

Is Lexapro escitalopram oxalate?

"The drug Lexapro is available in either tablet or liquid form. The tablets come in three different strengths (5mg, 10mg, 20mg) and are round with a film coating. The 10 and 20mg tablets are also scored so they can be easily broken in half if needed." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Escitalopram Oxalate

Image of Icahn School of Medicine at Mount Sinai, Mount Sinai West in New York, United States.
Phase-Based Progress Estimates
1
Effectiveness
1
Safety

Deep Brain Stimulation (DBS) For Treatment Resistant Depressionfor Major Depressive Disorder

25 - 70
All Sexes
New York, NY
Of the estimated 30 million Americans who suffer from Major Depressive Disorder, approximately 10% are considered treatment resistant. Deep brain stimulation (DBS) to a region of the brain called the subcallosal cingulate (SCC) is an emerging strategy for treatment resistant depression (TRD), which involves placement of electrodes in a specific region of the brain and stimulating that area with electricity. This is believed to reset the brain network responsible for symptoms and results in a significant antidepressant response. A series of open-label studies have demonstrated sustained, long-term antidepressant effects in 40-60% of patients who received this treatment. A challenge to the effective dissemination of this fledgling treatment is the absence of biomarkers (objective, measureable indications of the state of the body and brain) to guide device placement and select stimulation parameters during follow-up care. By using a DBS device called the Percept PC (Medtronic, Inc) which has the ability to both deliver stimulation to and record electrical signals directly from the brain, this study aims to identify changes in local field potentials (LFPs), specific electrical signals that are thought to represent how the brain communicates information from one region to another, to see how this relates to DBS parameter settings and patient depressive symptomatology. The goal of this study is to study LFPs before and during active DBS stimulation to identify changes that correlate with the antidepressant effects of SCC DBS. The study team will recruit 10 patients with TRD and implant them with the Percept PC system. Participants will be asked to complete short questionnaires and collect LFP data twice daily for the first year of the study, as well as have weekly in person research procedures and assessments with the study team for up to one year. These include meetings with the study psychiatrist, psychologist, symptom ratings, and movement, voice, and video recordings. A brief discontinuation experiment will be conducted after 6 months of stimulation, in which the stimulation will be turned off and patterns of LFP changes will be recorded. The entire study is expected to last about 5 years, parcellated into several study phases. All participants are required to live in the New York metropolitan area for the first several months of the study.
Recruiting
Has No Placebo
Icahn School of Medicine at Mount Sinai, Mount Sinai WestHelen Mayberg, MD
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.
Have you considered Escitalopram Oxalate clinical trials? We made a collection of clinical trials featuring Escitalopram Oxalate, we think they might fit your search criteria.