What is Escitalopram Oxalate
EscitalopramThe Generic name of this drug
Treatment SummaryEscitalopram is an antidepressant medication used to treat depression and anxiety. It works by increasing the amount of the chemical serotonin in the brain. It is more potent and effective than citalopram, its parent drug. Escitalopram is also known to have fewer side effects than other drugs in its class. It works faster than other antidepressants and has a higher degree of selectivity for the serotonin transporter, which may explain its superior efficacy.
Lexaprois the brand name
Escitalopram Oxalate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lexapro
Escitalopram
2002
348
Effectiveness
How Escitalopram Oxalate Affects PatientsEscitalopram is a type of medicine called a selective serotonin re-uptake inhibitor (SSRI). It works by increasing the amount of serotonin in the brain and can help treat certain mental health conditions. Though it is considered to be effective faster than other SSRIs, there is still a risk of abnormal bleeding and serotonin syndrome if taken with other medications that affect the body's ability to stop bleeding. If you need to stop taking escitalopram, make sure to do it slowly over time.
How Escitalopram Oxalate works in the bodyEscitalopram works by blocking the re-uptake of serotonin in the brain. This increases the amount of serotonin available in the brain, which helps reduce symptoms of depression. It does this by binding to a special site on the serotonin transporter called the orthosteric binding site. It also binds to a secondary site called an allosteric site, making it more effective than other selective serotonin re-uptake inhibitors. Long-term use of escitalopram will desensitize serotonin receptors, allowing for a longer-lasting effect. Escitalopram does not bind to many other receptors and any minor activity may lead to
When to interrupt dosage
The suggested measure of Escitalopram Oxalate is contingent upon the diagnosed condition, including Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression. The quantity of dosage is reliant upon the method of delivery as shown in the table beneath.Condition
Dosage
Administration
Generalized Anxiety Disorder
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated
Obsessive-Compulsive Disorder
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated
Depression
20.0 mg, 5.0 mg, 10.0 mg, , 1.0 mg/mL, 15.0 mg, 5.0 mg/mL, 2.0 mg, 1.0 mg
, Oral, Tablet, film coated, Solution, Tablet, film coated - Oral, Solution - Oral, Tablet - Oral, Tablet, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Kit, Tablet, coated - Oral, Tablet, coated
Warnings
Escitalopram Oxalate has five contraindications and should not be administered concurrently with the circumstances mentioned in the following table.Escitalopram Oxalate ContraindicationsCondition
Risk Level
Notes
Toxoplasma Infections
Do Not Combine
Long QT Syndrome
Do Not Combine
Toxoplasma Infections
Do Not Combine
Prolonged QT Interval
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Escitalopram may interact with Toxoplasma Infections
Common Escitalopram Oxalate Drug Interactions
Drug Name
Risk Level
Description
Aclidinium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Aclidinium.
Artemether
Major
The risk or severity of QTc prolongation can be increased when Escitalopram is combined with Artemether.
Azelastine
Major
Escitalopram may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cimetropium
Major
The risk or severity of adverse effects can be increased when Escitalopram is combined with Cimetropium.
Dronedarone
Major
Escitalopram may increase the QTc-prolonging activities of Dronedarone.
Escitalopram Oxalate Toxicity & Overdose RiskPeople who overdose on escitalopram may experience dizziness, seizures, extreme drowsiness, nausea, vomiting, low blood pressure, rapid heart rate, and changes to the heart rhythm. There is no known antidote for escitalopram overdose, so treatment should focus on monitoring vital signs and providing supportive care as needed. Since escitalopram is absorbed into the body's tissues, methods such as forced diuresis, dialysis, and other treatments to remove the drug from the bloodstream are unlikely to be helpful.
Escitalopram Oxalate Novel Uses: Which Conditions Have a Clinical Trial Featuring Escitalopram Oxalate?
231 active clinical trials are examining the potential of Escitalopram Oxalate to provide relief from Obsessive-Compulsive Disorder, Generalized Anxiety Disorder and Depression.Condition
Clinical Trials
Trial Phases
Obsessive-Compulsive Disorder
15 Actively Recruiting
Not Applicable, Phase 3
Generalized Anxiety Disorder
34 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Phase 1
Depression
200 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Phase 4, Early Phase 1
Escitalopram Oxalate Reviews: What are patients saying about Escitalopram Oxalate?
5Patient Review
9/23/2022 I'm very pleased with how this medication has been working for me. I was struggling with anxiety and depression, but now I'm doing much better. It's important to start slowly with a lower dosage and increase as needed; results won't be immediate, so give it at least 2-3 weeks before you make any decisions!
5Patient Review
2/9/2022 After my husband died a year ago, I was able to cope for the first few months. However, as events and anniversaries came up, I became more depressed. My doctor recommended Lexapro and started me on a 5mg daily dose. I have had no side effects and can now deal with day-to-day living much better. I've actually gained 10 pounds over the past year--which is something of a relief because I lost 15 pounds in the two months after he passed away from barely eating anything.
4.3Patient Review
8/13/2022 I've been on this medication for three months. It's made me very horny and up for sex all the time, which can be great, but also a little overwhelming. I'm not sure if I should keep taking it or not.
4.3Patient Review
6/8/2022 As a student, I find this medicine incredibly helpful in managing stress and anxiety. Sometimes I do take more than recommended, but it always helps me out.
4Patient Review
4/19/2022 This treatment helps me stay level-headed and in a good space.
3.3Patient Review
8/9/2022 Withdrawal from this drug can be difficult and doctors should be consulted before quitting.
3Patient Review
8/26/2022 I swapped to this treatment about two years ago and it helped decrease my panic attacks from 20mg to 10mg. However, I recently stopped taking the medication entirely and today experienced a terrible withdrawal attack. Please don't make the same mistake I did- speak with your GP before making any changes to your dosage.
3Patient Review
6/30/2022 I've been taking this medication on and off for a few years now to help with anxiety and depression. I love how well it works, but if I miss even a dose, I have severe withdrawal symptoms like migraines and nausea.
2.7Patient Review
11/13/2022 I've been taking this medicine for almost three weeks now and I'm experiencing more panic attacks and worse headaches than before. It was hard to sleep at first, but now I'm feeling sleepy all day long.
2.7Patient Review
2/14/2022 I've been on this medication for a month now and my anxiety has only gotten worse. My doctor wants me to give it two more weeks, but I don't know if I can handle it.
2Patient Review
4/23/2022 I have issues with bad panic attacks, so I'm always looking for treatments that can help. Unfortunately, this isn't one of them. It's made my asthma worse and I feel constantly bloated and anxious. I've tried it twice now and hated it both times.
2Patient Review
1/31/2022 I had some serious emotional ups and downs, as well as digestive problems, while taking this medication. Unfortunately, it was also ineffective in treating my condition.
1Patient Review
6/21/2022 I would not recommend this medication to anyone. I experienced a whole host of negative side effects, including nausea, weakness, and loss of appetite. This medicine made my condition worse instead of better.
Patient Q&A Section about escitalopram oxalate
Is escitalopram a form of Xanax?
"While both drugs may cause some of the same side effects, they are in different drug classes. Lexapro is a selective serotonin reuptake inhibitor (SSRI), while Xanax is a benzodiazepine." - Anonymous Online Contributor
Unverified Answer
Is Lexapro escitalopram oxalate?
"The drug Lexapro is available in either tablet or liquid form. The tablets come in three different strengths (5mg, 10mg, 20mg) and are round with a film coating. The 10 and 20mg tablets are also scored so they can be easily broken in half if needed." - Anonymous Online Contributor
Unverified Answer