Triad

Insomnia, Neurotic depression, Depression + 8 more
Treatment
20 Active Studies for Triad

What is Triad

DoxepinThe Generic name of this drug
Treatment SummaryCalcium carbonate is a medication used to reduce stomach acid. It works by neutralizing the hydrochloric acid in the stomach, which can help to reduce symptoms associated with heartburn, upset stomach, and acid indigestion. Calcium carbonate may also be taken as a nutritional supplement or to treat calcium deficiency.
Sinequanis the brand name
image of different drug pills on a surface
Triad Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Sinequan
Doxepin
1969
307

Effectiveness

How Triad Affects PatientsGastric-peptic disease is caused by an imbalance between protective substances like mucus, bicarbonate, and prostaglandin and aggressive substances like hydrochloric acid, pepsin, and bacteria called H. pylori. Antacids help to restore the balance of these substances, reducing pepsin activity and increasing bicarbonate and prostaglandin secretion. Calcium carbonate has an acid-neutralizing capacity of 58 mEq/15 ml. When taken as a supplement, it helps to increase calcium stores in the body.
How Triad works in the bodyCalcium carbonate is a salt that helps to reduce the acidity of stomach secretions by neutralizing hydrochloric acid. It also blocks the action of pepsin, an enzyme involved in digestion. This helps protect the stomach lining and can increase the production of bicarbonate and prostaglandins. When calcium carbonate neutralizes hydrochloric acid, it forms calcium chloride, carbon dioxide, and water. About 90% of calcium chloride is converted to calcium carbonate and calcium phosphate, which are not easily dissolved.

When to interrupt dosage

The proposed dosage of Triad is contingent upon the diagnosed condition, for example Gastric Ulcer, Dyspepsia and Acid dyspepsia. The amount of dosage also relies upon the method of delivery (e.g. Tablet or Oral) featured in the table beneath.
Condition
Dosage
Administration
Insomnia
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Neurotic depression
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Depression
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Generalized Anxiety Disorder
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Neuropathic Pain
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Itching
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Depressive Disorder, Major
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Behcet Syndrome
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Alcoholism
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Depressive Disorder, Major
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated
Neurodermatitis
, 10.0 mg/mL, 10.0 mg, 25.0 mg, 50.0 mg, 75.0 mg, 100.0 mg, 0.05 mg/mg, 150.0 mg, 3.0 mg, 6.0 mg, 5.0 %
Oral, , Solution, concentrate, Solution, concentrate - Oral, Capsule, Capsule - Oral, Topical, Cream, Cream - Topical, Tablet, Tablet - Oral, Solution, Solution - Oral, Tablet, film coated - Oral, Tablet, film coated

Warnings

Triad Contraindications
Condition
Risk Level
Notes
untreated narrow angle glaucoma
Do Not Combine
Pulse Frequency
Do Not Combine
Urinary Retention
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Doxepin may interact with Pulse Frequency
There are 20 known major drug interactions with Triad.
Common Triad Drug Interactions
Drug Name
Risk Level
Description
4-Methoxyamphetamine
Major
Doxepin may increase the vasopressor activities of 4-Methoxyamphetamine.
Acepromazine
Major
Doxepin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Doxepin is combined with Aclidinium.
Alfuzosin
Major
Doxepin may increase the hypotensive activities of Alfuzosin.
Aripiprazole
Major
Doxepin may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
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Triad Novel Uses: Which Conditions Have a Clinical Trial Featuring Triad?

75 active clinical trials are presently analyzing the potential of Triad in treating Hypovitaminosis D, Fracture and Calcium and Vitamin D Deficiency Disorders.
Condition
Clinical Trials
Trial Phases
Generalized Anxiety Disorder
183 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 4, Phase 1, Phase 3
Depressive Disorder, Major
0 Actively Recruiting
Insomnia
0 Actively Recruiting
Depression
306 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Early Phase 1, Phase 4, Phase 3
Alcoholism
7 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Neurotic depression
0 Actively Recruiting
Depressive Disorder, Major
0 Actively Recruiting
Itching
2 Actively Recruiting
Phase 3, Not Applicable
Behcet Syndrome
1 Actively Recruiting
Not Applicable
Neuropathic Pain
4 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Neurodermatitis
0 Actively Recruiting

Triad Reviews: What are patients saying about Triad?

4Patient Review
5/18/2010
Triad for Migraine Headache
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about triad

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does triad mean three?

"A trio is three people or things considered as one unit."

Answered by AI

Do the triads still exist?

"Although they are not as prevalent as they used to be, there are still remnants of former gangs and societies. The governments of Malaysia and Singapore have taken measures to reduce crime, which has caused these societies to go into hiding (especially in Singapore). Triads were also common in Vietnamese cities with large Chinese populations (especially Cantonese and Teochew)."

Answered by AI

What are examples of triads?

"A triad is a three-member social group. Triads are said to be more stable than dyads and they allow for more complex relationships. An example of a triad would be three college students that share an apartment. So next time you hear someone say that 'three's a crowd,' you can respond by saying that three is actually a triad."

Answered by AI

Clinical Trials for Triad

Image of Lincoln Middle School in Cottage Grove, United States.

Behavioral Interventions for Depression in Students

Any Age
All Sexes
Cottage Grove, OR
The goal of this clinical trial is to learn if two behavioral interventions work to reduce office disciplinary referrals, improve attendance, and reduce depression and anxiety in 7th grade students. This project combines two evidence-based programs-the Inclusive Skill-building Learning Approach (ISLA) for school-wide discipline reform and the Family Check-Up Online (FCU-O) for family-centered support-in an adaptive design to examine the unique and additive effects of these interventions on these child behavior outcomes. The main questions it will answer are: 1. What is the relative efficacy of ISLA vs. School-as-Usual? 2. What is the optimal sequencing of these interventions? 3. Which overall sequence of intervention strategies was most effective? Researchers will compare 6 combinations of these interventions to see which combination and sequencing provides the best student outcomes. School personnel participating in the project will be trained to implement the two interventions at their school. They will answer surveys in the fall, winter, and spring of their year of participation. Parent and Youth participants will complete surveys at baseline and then again 6 months and 12 months later.
Waitlist Available
Has No Placebo
Lincoln Middle School (+12 Sites)Beth Stormshak, PhD
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Living Well Program for Anxiety in Breast Cancer

18+
Female
Los Angeles, CA
The goal of this study is to evaluate the efficacy and cost-effectiveness of the Living Well Program, a digital therapeutic application with telecoaching support, in breast cancer patients with moderate-to-severe anxiety. The main question the study aims to answer is: does digital cognitive-behavioral therapy-based interventions decrease the overall healthcare costs of patients with stage II to IV breast cancer? The study has one group of participants who will use the Living Well app and telecoaching support. This group will be compared to retroactively matched controls. Over 3 months, patients will complete 21 mental health modules and 5 telecoaching sessions. In the following 3 months, they will complete any outstanding telecoaching sessions and modules while still being monitored, even if they finished all modules and sessions in the first 3 months. The 6 months after that will be the follow-up phase. They will still have access to the Living Well app and may continue to use it, and they will complete the same assessment questionnaires as baseline to identify any changes in their overall mental health.
Waitlist Available
Has No Placebo
Cedars-Sinai Medical CenterScott Irwin, MD
Have you considered Triad clinical trials? We made a collection of clinical trials featuring Triad, we think they might fit your search criteria.Go to Trials
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AI Chatbot for Postpartum Loneliness

18+
Female
La Jolla, CA
The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth. The main questions this study aims to answer are: * Does using the chatbot improve postpartum pelvic floor health knowledge? * Does using the chatbot help reduce feelings of loneliness during the postpartum period? * Does using the chatbot impact pelvic floor symptoms? Researchers will compare standard postpartum care to standard care plus the chatbot. Participants will: Be assigned by chance (like flipping a coin) to standard postpartum care with or without access to the chatbot. If in the chatbot group, participants will receive education and support via the chatbot over a 4-week period. Both groups will complete questionnaires to measure their pelvic floor knowledge, pelvic floor symptoms, feelings of loneliness, depression, infant bonding, perceived social support, adverse childhood experiences, and peri-traumatic distress. The chatbot was created by urogynecology experts in collaboration with UC San Diego computer science and biomedical informatics researchers. The chatbot is designed to give new mothers personalized, evidence-based information and support in real time.
Waitlist Available
Has No Placebo
University of California San Diego
Image of Mayo Clinic in Florida in Jacksonville, United States.

Virtual Reality for Cancer

18 - 90
All Sexes
Jacksonville, FL
This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer patients undergoing treatment. Virtual reality (VR) is a technology that allows users to experience and interact with three-dimensional, computer-generated environments that simulate the real world or imagined settings. The VR intervention consists of a preloaded with immersive environments designed to engage the senses through simulated sights and sounds. This may include a walk through of a serene forest, exploring vibrant coral reefs, swimming with dolphins, or standing at the base of a majestic waterfall. These environments are created to provide a relaxing and engaging experience. Completing the VR intervention may be a safe and effective way to improve quality of life, reduce anxiety, enhance focus, and promote healthy living for cancer patients undergoing treatment.
Recruiting
Has No Placebo
Mayo Clinic in FloridaJuan C. Cardenas Rosales, MD
Have you considered Triad clinical trials? We made a collection of clinical trials featuring Triad, we think they might fit your search criteria.Go to Trials
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Virtual Reality Reward Training for Depression

18+
All Sexes
Los Angeles, CA
The purpose of this study is to compare the effects of enhanced Virtual Reality-Reward Training (eVR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. Enhanced VR-Reward Training is a novel intervention aimed at enhancing savoring of positive experiences among individuals with depression and low positive affect through guided imaginal recounting following immersion in positive VR experiences. The current study tests an enhanced version of this training using improved virtual reality technology. Target enrollment is 80 participants with low positive affect, depression, and impaired functioning, who are at least 18 years old, who will be randomly assigned to 7 weeks of either enhanced Virtual Reality-Reward Training (VR-RT) or Virtual Reality-Memory Training (VR-MT). Participants will complete in-person VR sessions, laboratory assessments, self-report questionnaires as part of the study. A subset of 8 participants randomly assigned to VR-RT will complete fMRI scans and EMA surveys. The total length of participation is around 3 months.
Phase 2
Recruiting
University of California, Los Angeles
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Safe and Sound Protocol for Substance Abuse

18 - 75
All Sexes
Wernersville, PA
This study will explore whether the use of the Safe and Sound Protocol (SSP) app is an effective adjunct to treatment as usual (TAU) in individuals with co-occurring substance use disorders and trauma. This study will recruit 129 participants (100 completers) randomized to receive either active or sham SSP in addition to TAU. Participants will utilize the SSP for a minimum of three hours to a maximum of five hours for a total of seven days. Data will be collected at both pre- and post-test. Data to be collected will include measures on affect, anxiety, personality, mindfulness, and posttraumatic stress disorder symptoms. The SSP has shown effectiveness in reducing symptoms of anxiety, depression, and trauma symptoms in pilot studies conducted at other locations. This will be the first study to examine the effectiveness of SSP with individuals with co-occurring SUD and trauma.
Waitlist Available
Device
Caron Treatment CentersErin Deneke, PhD
Have you considered Triad clinical trials? We made a collection of clinical trials featuring Triad, we think they might fit your search criteria.Go to Trials
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