Betadine vs Sterile Water for Catheterization
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial evaluates the effectiveness of different cleaning methods before placing a temporary catheter into the bladder. It compares cleaning with Betadine (Povidone-Iodine, a common antiseptic) and sterile water to determine which method results in fewer bacteria in the urine and less discomfort for patients. The goal is to assess whether sterile water can be as effective and comfortable as Betadine. Suitable participants are those requiring an in-office catheter procedure without a history of frequent urinary tract infections. As a Phase 4 trial, this research involves an FDA-approved treatment, aiming to enhance patient comfort and effectiveness.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What is the safety track record for these treatments?
Research shows that Povidone-Iodine, also known as Betadine, is generally safe for use on the skin. This common antiseptic prevents infections and has proven effective for cleaning the skin before medical procedures. When used with catheters, it helps lower infection risk.
Comparisons with another antiseptic, Chlorhexidine, reveal that some studies suggest Chlorhexidine might be slightly more effective in preventing infections. However, both are considered safe and widely used.
For those considering joining a trial involving Povidone-Iodine, it is important to know that it has a strong safety record. While some people might experience minor skin irritation, serious side effects are rare.12345Why are researchers enthusiastic about this study treatment?
Researchers are excited about this trial because it explores the effectiveness of two different periurethral preparation solutions for catheterization: Betadine and sterile water. Betadine, which contains povidone-iodine, is known for its strong antiseptic properties, potentially reducing the risk of infection. On the other hand, sterile water offers a simpler, non-antiseptic approach, which might be beneficial for patients with sensitivities to iodine or other antiseptics. By comparing these two methods, the study aims to provide insights into whether a non-antiseptic option could be just as effective or preferable in certain situations, potentially broadening the scope of catheterization preparation methods.
What evidence suggests that this trial's treatments could be effective for reducing bacteria and discomfort during catheterization?
Research has shown that Povidone-Iodine, also known as Betadine, effectively reduces infections when used with catheters. One study found that Povidone-Iodine significantly lowered infection rates from catheters by inhibiting bacterial growth when a catheter is placed in the bladder. In this trial, one group of participants will receive Betadine for periurethral preparation, while another group will receive sterile water. Sterile water primarily cleans and removes bacteria but does not kill bacteria like Betadine. The trial aims to determine if sterile water is as effective as Betadine in preventing bacteria in urine after catheter use.26789
Who Is on the Research Team?
Ankita Gupta, MD, MPH
Principal Investigator
University of Louisville
Are You a Good Fit for This Trial?
This trial is for individuals who require a temporary urinary catheter and are at risk of UTIs. Participants must be eligible for catheterization without any known allergies to Betadine or Povidone-Iodine, and should not have conditions that could interfere with the study outcomes.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo periurethral preparation with either Betadine or Sterile Water followed by catheterization
Follow-up
Participants are monitored for bacteruria and urethral pain after catheterization
What Are the Treatments Tested in This Trial?
Interventions
- Povidone-Iodine
- Sterile water
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Louisville
Lead Sponsor