Serax

Generalized Anxiety Disorder, Anxiety Disorders, Syndrome
Treatment
5 FDA approvals
20 Active Studies for Serax

What is Serax

OxazepamThe Generic name of this drug
Treatment SummaryOxazepam is a type of medication used to help with alcohol withdrawal and anxiety disorders. It is known to be more consistent in the body than other benzodiazepines, which means it is less likely to react differently in patients of different ages or with liver issues. Oxazepam is a metabolite of diazepam and temazepam, meaning it doesn't change much in the body after it is absorbed, making it unlikely to interact with other medications.
Oxazepamis the brand name
image of different drug pills on a surface
Serax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Oxazepam
Oxazepam
1987
30

Approved as Treatment by the FDA

Oxazepam, also called Oxazepam, is approved by the FDA for 5 uses including Anxiety Disorders and Alcohol Withdrawal Syndrome .
Anxiety Disorders
Helps manage Anxiety Disorders
Alcohol Withdrawal Syndrome
Generalized Anxiety Disorder
Syndrome
Anxiety Disorders
Helps manage Anxiety Disorders

Effectiveness

How Serax Affects PatientsOxazepam is a type of benzodiazepine that helps to reduce anxiety and cause sedation. It works by boosting the effects of a natural chemical in the brain (GABA) that helps to calm nervous activity. Oxazepam is not as strong as other benzodiazepines and its effects are shorter-lasting. Care should be taken when giving it to people who may have issues with low blood pressure, as it can lead to hypotension in rare cases.
How Serax works in the bodyOxazepam works by enhancing the effects of GABA, a natural chemical in the brain that helps reduce nerve activity. Oxazepam binds to specific sites on the GABA receptors, called benzodiazepine binding sites. This enhances the inhibitory effects of GABA, which helps to reduce epileptic nerve firing and treat epilepsy.

When to interrupt dosage

The proposed dosage of Serax is dependent upon the diagnosed state, including Anxiety Disorders, Syndrome and Generalized Anxiety Disorder. The quantity of dosage varies, based on the technique of delivery (e.g. Tablet - Oral or Capsule, gelatin coated) found in the table underneath.
Condition
Dosage
Administration
Syndrome
, 15.0 mg, 30.0 mg, 10.0 mg
, Oral, Capsule - Oral, Capsule, Capsule, gelatin coated - Oral, Tablet - Oral, Tablet, Capsule, gelatin coated
Generalized Anxiety Disorder
, 15.0 mg, 30.0 mg, 10.0 mg
, Oral, Capsule - Oral, Capsule, Capsule, gelatin coated - Oral, Tablet - Oral, Tablet, Capsule, gelatin coated
Anxiety Disorders
, 15.0 mg, 30.0 mg, 10.0 mg
, Oral, Capsule - Oral, Capsule, Capsule, gelatin coated - Oral, Tablet - Oral, Tablet, Capsule, gelatin coated

Warnings

Serax has four contraindications, so it should not be utilized concurrently with the conditions shown in the following table.Serax Contraindications
Condition
Risk Level
Notes
Open-angle glaucoma
Do Not Combine
Myasthenia Gravis
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Oxazepam may interact with Pulse Frequency
There are 20 known major drug interactions with Serax.
Common Serax Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of sedation and somnolence can be increased when Oxazepam is combined with Deutetrabenazine.
Ethanol
Major
Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Methadone
Major
Oxazepam may increase the central nervous system depressant (CNS depressant) activities of Methadone.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Oxazepam is combined with Oliceridine.
Serax Toxicity & Overdose RiskThe lowest toxic dose of oxazepam in rats and mice is greater than 8000mg/kg and 1540mg/kg, respectively. Symptoms of overdosing on oxazepam can range from mild to severe, and can even be fatal. Treatment includes pumping the stomach and providing supportive care. In some cases, the drug flumazenil may be used to help with treatment, but it may increase the risk of seizures for people who take benzodiazepines or antidepressants long-term.
image of a doctor in a lab doing drug, clinical research

Serax Novel Uses: Which Conditions Have a Clinical Trial Featuring Serax?

Presently, 396 active clinical trials are being conducted to examine the potential of Serax to ameliorate Anxiety Disorders, Syndrome and Generalized Anxiety Disorder.
Condition
Clinical Trials
Trial Phases
Generalized Anxiety Disorder
183 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 4, Phase 1, Phase 3
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Anxiety Disorders
56 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1

Serax Reviews: What are patients saying about Serax?

5Patient Review
11/8/2010
Serax for Anxious
Serax has been a dependable medication for me over the last 40 years. I've taken it in high doses when necessary and it's always worked as intended. If there are any long-term effects from taking this drug, I'd like to know about them.
5Patient Review
11/2/2010
Serax for Anxious
I've only been taking this for a few days following a TIA, but it seems to be helping me cut down on my drinking. So far, so good.
5Patient Review
2/17/2011
Serax for Anxious
This medication has been a game changer for me, easing my anxiety and improving my quality of life.
5Patient Review
8/29/2012
Serax for Anxious
I've been taking this medication for years to relieve anxiety and sometimes help me sleep better. I use it very sparingly, maybe only 50 tablets per year. It really does help when I have problems though. And unlike other solutions (like alcohol abuse), it's not habit-forming in the least bit.
5Patient Review
7/25/2011
Serax for Anxious
This medication has been a life-saver for me. I suffer from chronic anxiety and related symptoms, but taking just 15mg of Serax per day helps immensely.
5Patient Review
11/6/2009
Serax for Anxious
I'm not sure what the difference is between the dosages, but this one worked great for me.
5Patient Review
7/8/2010
Serax for Anxious
This treatment really helped me. I'm grateful for modern medicine.
5Patient Review
5/7/2009
Serax for Psychosis caused by Sudden Alcohol Withdrawal
5Patient Review
2/6/2013
Serax for Anxious
This treatment has really helped me out and I'm very grateful for it.
4.7Patient Review
4/30/2012
Serax for Anxious
This medication helped me a lot when I was getting dental work done. I have serious anxiety around needles and blood, so this really took the edge off.
4.7Patient Review
11/18/2009
Serax for Anxious
After I was diagnosed with Parkinson's, my doctor prescribed this treatment. I was originally taking it three times a day, but then he reduced it to once a day. Over time, I have stopped taking it except when my foot cramps up too much or when I am in an extremely anxious condition (about 1 time every week or two). It works well at relaxing my muscles.
4.3Patient Review
7/12/2010
Serax for Psychosis caused by Sudden Alcohol Withdrawal
I have diabetic neuropathy and have had a complete hysterectomy,gallbladder removal, and broke my shoulder and arm 4 months ago. The broken bones have not healed. The Serax works great but doctor will not prescribe enough. I take 4 10 milligrams pills a day and 1 hydrocodone. I take 40 units of insulin twice a day.
4Patient Review
7/21/2011
Serax for Anxious
Serax has been a huge help to me in managing my anxiety. Not only does it help with the mental symptoms, but also the physical ones like shortness of breath and profuse sweating.
3.7Patient Review
2/26/2011
Serax for Anxious
This drug has helped me with both my muscle tension and insomnia without making me excessively drowsy.
3.7Patient Review
10/22/2009
Serax for Anxious
Serax has been a life-saver for me. I used to drink at least a fifth of alcohol every day, and now I haven't had a drink in 30 days. I'm not entirely sure how it works, but it's made a huge difference for me nonetheless.
3Patient Review
3/15/2010
Serax for Osteoporosis
I didn't experience any side effects.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about serax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is serax and oxazepam the same thing?

"Oxazepam is a medication that has been around since 1965 and is available almost exclusively as a generic drug. The generic versions of the medication should work as well as prescription versions."

Answered by AI

Is serax a sleeping pill?

"Serax is a benzodiazepine used to treat anxiety disorders and alcohol withdrawal symptoms. It may also be used for sleep (insomnia)."

Answered by AI

What is the difference between serax and Xanax?

"Serax (oxazepam) is used to treat seizures that occur during alcohol withdrawal, and is also effective for short-term relief of anxiety symptoms. Xanax (alprazolam) is used to manage anxiety that is associated with depression, and works very quickly - usually within hours."

Answered by AI

What is the drug serax used for?

"This medication is used to treat anxiety and acute alcohol withdrawal. It belongs to a class of drugs called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming and anti-seizure effect."

Answered by AI

Clinical Trials for Serax

Image of Cedars-Sinai Medical Center in Los Angeles, United States.

Living Well Program for Anxiety in Breast Cancer

18+
Female
Los Angeles, CA
The goal of this study is to evaluate the efficacy and cost-effectiveness of the Living Well Program, a digital therapeutic application with telecoaching support, in breast cancer patients with moderate-to-severe anxiety. The main question the study aims to answer is: does digital cognitive-behavioral therapy-based interventions decrease the overall healthcare costs of patients with stage II to IV breast cancer? The study has one group of participants who will use the Living Well app and telecoaching support. This group will be compared to retroactively matched controls. Over 3 months, patients will complete 21 mental health modules and 5 telecoaching sessions. In the following 3 months, they will complete any outstanding telecoaching sessions and modules while still being monitored, even if they finished all modules and sessions in the first 3 months. The 6 months after that will be the follow-up phase. They will still have access to the Living Well app and may continue to use it, and they will complete the same assessment questionnaires as baseline to identify any changes in their overall mental health.
Waitlist Available
Has No Placebo
Cedars-Sinai Medical CenterScott Irwin, MD
Image of Mayo Clinic in Florida in Jacksonville, United States.

Virtual Reality for Cancer

18 - 90
All Sexes
Jacksonville, FL
This clinical trial tests the safety, tolerability, and effectiveness of a virtual reality intervention to improve psychological symptom burden for cancer patients undergoing treatment. Virtual reality (VR) is a technology that allows users to experience and interact with three-dimensional, computer-generated environments that simulate the real world or imagined settings. The VR intervention consists of a preloaded with immersive environments designed to engage the senses through simulated sights and sounds. This may include a walk through of a serene forest, exploring vibrant coral reefs, swimming with dolphins, or standing at the base of a majestic waterfall. These environments are created to provide a relaxing and engaging experience. Completing the VR intervention may be a safe and effective way to improve quality of life, reduce anxiety, enhance focus, and promote healthy living for cancer patients undergoing treatment.
Recruiting
Has No Placebo
Mayo Clinic in FloridaJuan C. Cardenas Rosales, MD
Have you considered Serax clinical trials? We made a collection of clinical trials featuring Serax, we think they might fit your search criteria.Go to Trials
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Safe and Sound Protocol for Substance Abuse

18 - 75
All Sexes
Wernersville, PA
This study will explore whether the use of the Safe and Sound Protocol (SSP) app is an effective adjunct to treatment as usual (TAU) in individuals with co-occurring substance use disorders and trauma. This study will recruit 129 participants (100 completers) randomized to receive either active or sham SSP in addition to TAU. Participants will utilize the SSP for a minimum of three hours to a maximum of five hours for a total of seven days. Data will be collected at both pre- and post-test. Data to be collected will include measures on affect, anxiety, personality, mindfulness, and posttraumatic stress disorder symptoms. The SSP has shown effectiveness in reducing symptoms of anxiety, depression, and trauma symptoms in pilot studies conducted at other locations. This will be the first study to examine the effectiveness of SSP with individuals with co-occurring SUD and trauma.
Waitlist Available
Device
Caron Treatment CentersErin Deneke, PhD
Image of Cresap Laboratory in Evanston, United States.

Dream Yoga Inspired Intervention for Anxiety

18+
All Sexes
Evanston, IL
This is a feasibility study to test whether it is possible to deliver a program inspired by Tibetan Dream Yoga in a modern, accessible way. Dream Yoga is a set of contemplative practices that combine mental exercises during the day with techniques for becoming aware of dreaming within a dream (lucid dreaming) and engage in certain dream activities. The purpose of these practices is to help people explore and loosen rigid patterns of thought and behavior. In this study, the investigators are developing and testing a program that includes guided imagination, meditation, and lucid-dreaming practices, supported by virtual-reality experiences and home-based sleep-monitoring technology. Participants are randomly assigned to either the Dream-Yoga-inspired program or a comparison program focused on general health and sleep education. Because this is a feasibility trial, our main goals are to see whether people are willing and able to take part, whether they find the program acceptable, and whether the investigators can deliver it as planned. The investigators will also explore early signals of change in sleep, dreaming, and thinking. The long-term goal of this research is to determine if such interventions could be beneficial for supporting psychological well-being, improving sleep, and enhancing creativity and flexibility of thought.
Phase < 1
Waitlist Available
Cresap Laboratory (+1 Sites)
Image of Center for Technology and Behavioral Health (CTBH), Geisel School of Medicine at Dartmouth College in Lebanon, United States.

Advertising Claims for Anxiety and Depression

18+
All Sexes
Lebanon, NH
In the U.S., legal cannabis is frequently advertised as an effective treatment for mental health problems such as anxiety and depression-particularly online. States that have legalized cannabis have not implemented regulations to address this type of advertising. This project aims to investigate the influence of psychotherapeutic advertising claims (PAC) and mental health warning labels (WL) on online cannabis purchasing behaviors among light-to-moderate cannabis users with symptoms of depression and/or anxiety. The specific aims are to determine whether PAC increases cannabis purchasing intentions and whether a mental health WL can mitigate this effect. A realistic online cannabis shopping experience will be simulated using the digital Platform for Online Evaluation of Marijuana Marketing and Sales (POEMMS). The study will employ a between-subjects experimental design by randomizing 2,000 participants to one of four online stores that vary in PAC and WL content: (1) a control claims (CC)-only store, (2) a PAC store, (3) a WL store, and (4) a PAC + WL store. Participants will browse and select items as if making real purchases. Analyses will examine three primary outcomes to determine the influence of PAC and WL on purchasing behaviors: (1) total milligrams of THC purchased, (2) average potency (%THC) of products, and (3) overall number of products purchased. The long-term objective is to inform evidence-based cannabis policy and regulatory strategies by understanding the impact of cannabis marketing on vulnerable populations. This research is relevant to public health by addressing the potential risks associated with misleading cannabis marketing, which may lead to increased use and exacerbation of mental health symptoms among individuals with depression and anxiety. The project leverages a multidisciplinary team with expertise in addiction, mental health, epidemiology, and digital health technology. The findings have the potential to inform the development of targeted interventions and policies to reduce harms associated with cannabis advertising-ultimately contributing to better health outcomes and more effective regulation.
Waitlist Available
Has No Placebo
Center for Technology and Behavioral Health (CTBH), Geisel School of Medicine at Dartmouth CollegeJennifer Emond, PHD
Have you considered Serax clinical trials? We made a collection of clinical trials featuring Serax, we think they might fit your search criteria.Go to Trials
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Peer Support Services for Teen Mental Health

15 - 18
All Sexes
Dallas, TX
The goal of this pilot study is to test the effectiveness of a novel intervention for teenagers (ages 15-18) with mental health conditions who have been released from an acute care psychiatric facility. The intervention aims to reduce suicidality, depression, anxiety, re-hospitalization, and to improve mental health recovery by using an online recovery education and support program. The current standard of care (SOC) for these patients at discharge includes a discharge plan with a list of their medication(s), anticipated outpatient appointment(s), and corresponding information on when and where to find community resources. The intervention being tested involves the implementation of an online recovery education and support (RES) program, involving one-on-one and small group meetings led by trained teen peers (TPs) and peer support specialists (PSS). Participants will be assigned to either Cohort A or B for 8 weeks. Cohort A will be the intervention group with online access to an RES, TP, and PSS. * Week 1-4: One-on-one meetings with PSS and TP for education and support. Assessments will be completed at week 2 and 4. * Week 5 and 7: one-one meetings with PSS and TP for education and support. * Week 6 and 8: small group meetings with PSS, TP, and other participants. Assessments will be completed during Weeks 6 and 8. Cohort B will be the SOC group with no PSS, TP, or RES. * Weeks 1-4: Weekly check in phone calls with a member of the research team. Assessments will be completed at Weeks 2 and 4. * Weeks 5-8: Check in phone calls with a member of the research team every other week. Assessments will be completed at weeks 6 and8. Data collected from participant assessments, adherence to medication, and re-admittance to a psychiatric facility will be used to compare the intervention to the SOC.
Recruiting
Has No Placebo
The University of Texas Southwestern Medical CenterJoseph Guillory, M.D.
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Online Parent Education for Child Anxiety

18+
All Sexes
Boston, MA
The investigators are doing this research to test whether parents of children ages 2-7 can better manage their child's anxiety by completing a brief, online, self-guided parent education program. One way to provide anxiety management skills to more children, and to potentially prevent worsening outcomes, is to offer online and self-guided educational programs that parents can complete without a clinician. This randomized trial will evaluate the effects of two brief, online, self-guided parent education programs designed to improve parents' understanding of anxiety and teach parents way to help their children cope with anxiety. Parents will be randomly assigned to one of the three programs. The main aim of the study is to examine whether the parent programs, compared to an educational control reduce parental accommodation of anxiety across a 1-, 4-, and 8-month follow-up period. As a secondary aim, the investigators will explore whether the parent programs reduce children's anxiety symptoms over the 8-month follow-up period. Results will inform the development of a scalable, low-cost model for promoting access to evidence-based treatment to young children.
Recruiting
Online Trial
Massachusetts General Hospital
Have you considered Serax clinical trials? We made a collection of clinical trials featuring Serax, we think they might fit your search criteria.Go to Trials
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