Pregabalin

Seizures, Peripheral Nervous System Diseases, Generalized Anxiety Disorder + 9 more
Treatment
12 FDA approvals
20 Active Studies for Pregabalin

What is Pregabalin

PregabalinThe Generic name of this drug
Treatment SummaryPregabalin is a medication used to treat nerve pain, shingles pain, and fibromyalgia. It works by affecting the levels of a chemical called GABA, which is a neurotransmitter that helps with pain signals. The exact way that pregabalin works is not fully understood, but it is believed to bind to a subunit of voltage-dependent calcium channels in the brain. Pregabalin is sold under the brand name Lyrica and Lyrica CR (extended release). Using pregabalin irresponsibly or in large doses can cause dependence, particularly in people with a history of substance abuse.
Lyricais the brand name
image of different drug pills on a surface
Pregabalin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lyrica
Pregabalin
2004
579

Approved as Treatment by the FDA

Pregabalin, also called Lyrica, is approved by the FDA for 12 uses which include Neuropathic Pain and Diabetic Peripheral Neuropathic Pain (DPN) .
Neuropathic Pain
Helps manage Neuropathic Pain
Diabetic Peripheral Neuropathic Pain (DPN)
Helps manage Diabetic Peripheral Neuropathic Pain (DPN)
Neuropathic Pain
Helps manage Neuropathic Pain
Seizures
Diabetic Neuralgia
Helps manage Diabetic Peripheral Neuropathic Pain (DPN)
Postherpetic Neuralgia
Partial-Onset Seizures
Spinal Cord Injuries (SCI)
Helps manage Spinal Cord Injuries (SCI)
Fibromyalgia (FM)
Helps manage Fibromyalgia (FM)
Spinal Cord Injury
Helps manage Spinal Cord Injuries (SCI)
Neuralgia, Postherpetic
Fibromyalgia
Helps manage Fibromyalgia (FM)

Effectiveness

How Pregabalin Affects PatientsPregabalin is structurally similar to gamma-aminobutyric acid (GABA) but does not bind to GABA receptors. Instead, it attaches itself to calcium channels in the brain which helps reduce the amount of pain signals that are sent out. It does not influence dopamine, serotonin, opiate receptors, sodium channels, or the enzyme cyclooxygenase.
How Pregabalin works in the bodyWe don't know exactly how pregabalin works, but it appears to bind to voltage-gated calcium channels in the central nervous system. This connection helps reduce the amount of excitatory neurotransmitters, like glutamate and norepinephrine, that are released. It also prevents the alpha2-delta subunit from being transported to the spinal dorsal horn. Pregabalin is related to GABA, but it does not bind directly to GABA or benzodiazepine receptors.

When to interrupt dosage

The advised dose of Pregabalin is contingent upon the declared ailment, such as Neuralgia, Fibromyalgia and Postherpetic Neuralgia. The measure can be seen in the table below, in accordance with the method of delivery (e.g. Capsule or Tablet, film coated, extended release).
Condition
Dosage
Administration
Vitamin B 12 Deficiency
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Neuropathic Pain
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Epilepsy
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
No gastrointestinal absorption problems
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Neuralgia
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Spinal Cord Injury
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Neuralgia, Postherpetic
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Seizures
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Generalized Anxiety Disorder
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Diabetic Neuralgia
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Fibromyalgia
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral
Peripheral Nervous System Diseases
, 50.0 mg, 25.0 mg, 75.0 mg, 100.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 225.0 mg, 20.0 mg/mL, 165.0 mg, 82.5 mg, 330.0 mg
Capsule, Capsule - Oral, , Oral, Solution - Oral, Solution, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release, Tablet, extended release, Tablet, extended release - Oral

Warnings

Pregabalin Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Pregabalin may interact with Pulse Frequency
There are 20 known major drug interactions with Pregabalin.
Common Pregabalin Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Ethanol
Major
Pregabalin may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Hydroxyzine.
Lorazepam
Major
The risk or severity of adverse effects can be increased when Pregabalin is combined with Lorazepam.
Mobocertinib
Major
The risk or severity of QTc prolongation can be increased when Pregabalin is combined with Mobocertinib.
Pregabalin Toxicity & Overdose RiskPregabalin has been linked to a range of side effects affecting the central nervous system and cognition, such as dizziness, balance problems, confusion, sleepiness, tremors, difficulty concentrating, tiredness, and euphoria. When taken in high doses (up to 11,500 mg), the most common symptoms of overdose include sleepiness, confusion, restlessness, agitation, depression, and seizures. There is no antidote for pregabalin overdose, so general supportive care should be given. In severe cases, unabsorbed pregabalin may be eliminated with methods such as gastric lavage or emesis, or
image of a doctor in a lab doing drug, clinical research

Pregabalin Novel Uses: Which Conditions Have a Clinical Trial Featuring Pregabalin?

111 active trials are currently in progress to investigate the potential of Pregabalin for alleviating Peripheral Neuropathy, Postherpetic Neuralgia and Gastrointestinal Absorption Difficulties.
Condition
Clinical Trials
Trial Phases
Diabetic Neuralgia
4 Actively Recruiting
Phase 1, Phase 2, Phase 3
Spinal Cord Injury
68 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Early Phase 1, Phase 1
Peripheral Nervous System Diseases
2 Actively Recruiting
Not Applicable
Generalized Anxiety Disorder
7 Actively Recruiting
Not Applicable, Phase 2, Phase 3
Epilepsy
0 Actively Recruiting
Vitamin B 12 Deficiency
0 Actively Recruiting
Fibromyalgia
0 Actively Recruiting
No gastrointestinal absorption problems
0 Actively Recruiting
Seizures
5 Actively Recruiting
Phase 3, Phase 2, Phase 1
Neuralgia
0 Actively Recruiting
Neuralgia, Postherpetic
0 Actively Recruiting
Neuropathic Pain
4 Actively Recruiting
Not Applicable, Phase 1, Phase 2

Pregabalin Reviews: What are patients saying about Pregabalin?

5Patient Review
5/12/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I've been dealing with pain from my L1-L3 fracture for 40 years, and this is the first time I've had medication that's really helped. It's allowed me to get off of heroin and finally live a somewhat normal life. The weight gain and clumsiness are unfortunate side effects, but they're worth it to be able to function without constant pain.
5Patient Review
6/1/2022
Pregabalin for Neuropathic Pain
Without this medication, I would be unable to walk due to the severe neuropathy from diabetes that I have. This has been a lifesaver for me, allowing me to live relatively normally despite my chronic condition.
5Patient Review
5/12/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I've been dealing with a lot of pain for 40 years, ever since I fractured my L1-L3 vertebrae. I'm currently taking 300 mg of Pregabalin, 2 15 mg OxyContin, and 1 1mg alprozolam. These have finally helped me manage the pain and live a relatively normal life. Yes, there are some side effects like weight gain and clumsiness, but they're nothing compared to the alternative of living in constant pain.
5Patient Review
5/19/2022
Pregabalin for Neuropathic Pain
After my stroke, I was left with intense neuropathic pain. This medication has been a godsend in terms of relief, though I find that the effect wears off after a while. Still, it's better than nothing.
5Patient Review
6/1/2022
Pregabalin for Neuropathic Pain
This medication has been integral to me being able to walk, due to the severe neuropathy I experience from diabetes and multiple foot surgeries.
5Patient Review
5/19/2022
Pregabalin for Neuropathic Pain
After my stroke, I was in a lot of pain from neuropathy. The previous medication I was on stopped being effective, so I switched to Lyrica. It's been really helpful in managing the pain and has allowed me to get some relief.
4.3Patient Review
5/15/2022
Pregabalin for Neuropathic Pain
My foot and toes were in a lot of pain before I started this treatment, but I immediately felt relief. Recently, though, the pain has been coming back, so I've had to up my dosage. That's why I'm on this page, doing research to see how much more I can take.
4.3Patient Review
6/23/2022
Pregabalin for Neuropathic Pain
I've been using this medication for about a week now, and I've found that it offers me pain relief for around four to five hours. The first two of those hours are the strongest in terms of pain reduction, but even the last few hours offer some significant benefits. Additionally, this drug has helped to reduce my anxiety and cravings for cigarettes. So far, no negative side effects to report – though I am planning on discussing an increase in dosage with my doctor given that I still feel sharp pains in my arm from time to time.
4.3Patient Review
5/15/2022
Pregabalin for Neuropathic Pain
I was in a lot of pain in my left foot and toes. This treatment really helped me, but I've had to up the dosage lately. I'm looking for more information on how much I can take.
4.3Patient Review
6/23/2022
Pregabalin for Neuropathic Pain
This medication provides me with approximately four to five hours of pain relief, which is definitely welcome. I haven't experienced any negative side effects yet, but I'm going to ask my doctor about increasing the dosage because I can still feel some sharp pains in my arm.
4Patient Review
7/18/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I take 75mg at night to help ease nerve pain in my leg from a spinal stenosis. It provides around 6 hours of relief which enables me to sleep. I'm really happy with this product and how it's helped me manage my pain.
4Patient Review
7/18/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
This medication helps me a lot with the pain I experience from my spinal stenosis. It eases the nerve pain in my leg and allows me to sleep for around six hours.
3.7Patient Review
6/9/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I've been using this treatment for years to help with my back problems and neuropathy. It works pretty well, all things considered.
3.7Patient Review
6/9/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I've been using this treatment for years to help with my back pain and neuropathy. It works well, but isn't a cure-all.
2.7Patient Review
6/22/2022
Pregabalin for Neuropathic Pain
I was dealing with a lot of pain in my back and legs due to a bulging disc. Unfortunately, this product didn't do anything to help relieve that pain.
2.7Patient Review
6/22/2022
Pregabalin for Neuropathic Pain
I didn't find this product effective at all in treating my muscle spasms caused by a bulging disc.
2.3Patient Review
5/17/2022
Pregabalin for Neuropathic Pain
The first dose was great, but I didn't feel like it worked as well after that. I kept taking it, hoping it would help, but alas, I saw no difference.
2.3Patient Review
5/17/2022
Pregabalin for Neuropathic Pain
The first dose was great, but I didn't see any difference after that. Started taking ALA afterwards in the hopes that it would help.
2Patient Review
4/10/2022
Pregabalin for Disorder characterized by Stiff, Tender & Painful Muscles
I found that this medication really impacted my memory and made it hard to concentrate. My appetite also increased quite a bit while I was taking it.
2Patient Review
4/10/2022
Pregabalin for Disorder characterized by Stiff, Tender & Painful Muscles
I found that this medication really decreased my ability to concentrate and remember things. My appetite also increased quite a bit while I was taking it.
1.3Patient Review
8/17/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I was advised to take one pill, then two if one did not work and then max at three. One did nothing, two did not reduce the pain but I felt like I had a hangover the next day along with a migraine headache. I tried three = good for pain but horrible hangover and disorientation the next day and one half.
1.3Patient Review
8/17/2022
Pregabalin for Nerve Pain from Spinal Cord Injury
I followed the instructions and took one pill, then two when that didn't work. The pain wasn't any better, but I felt awful the next day. Disoriented and with a splitting headache on top of the original pain. Three pills did help with the pain, but then I felt like I was losing my mind from the hangover. Overall, this was a terrible option for me.
1Patient Review
7/19/2022
Pregabalin for Disorder characterized by Stiff, Tender & Painful Muscles
This pill is extremely dangerous. I was walking into walls and having all sorts of other problems when I took it. When it was offered to my elderly mother, I said no way. The weight gain from this pill is so bad that it should be banned worldwide. If a little child got this, I don't know if they would survive. It's an evil pill that causes terrible mental problems like depression and suicidal thoughts.
1Patient Review
8/18/2022
Pregabalin for Acute Pain Following an Operation
I was given this medication after two failed spinal operations. I have been experiencing a lot of nerve pain, so they increased my dose to 225mg per day. I take one in the morning and two at night, but my pain is still here.
1Patient Review
7/19/2022
Pregabalin for Disorder characterized by Stiff, Tender & Painful Muscles
This pill is dangerous. I was walking into walls and just everything. When it was offered to my elderly mum, there was no way. The weight gain from this pill is so bad. Lyrics should be banned worldwide. If a little child got this, I don't know if they would survive. Evil pill.. get rid of it for good.
1Patient Review
8/18/2022
Pregabalin for Acute Pain Following an Operation
I was given this medication after two failed spinal surgeries. I have been dealing with a lot of nerve pain, and they increased my dose to 225mg per day. I take one pill in the morning and two at night, but I'm still in a lot of pain.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about pregabalin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is pregabalin for mental health?

"Pregabalin is a drug that is related to the brain chemical GABA, which has a calming effect. Pregabalin reduces the release of brain chemicals that have a stimulating effect and can help with anxiety."

Answered by AI

What does pregabalin do to the nerves?

"Pregabalin is a medication used to treat seizures. It works by reducing the number of pain signals sent out by damaged nerves in the body."

Answered by AI

What is pregabalin used for?

"Pregabalin can help relieve certain types of nerve pain. It is typically used to treat conditions such as epilepsy, anxiety, and diabetic nerve pain. However, it can also be effective in treating nerve pain caused by other conditions such as shingles or an injury."

Answered by AI

Is pregabalin good for sleep?

"Treatment with pregabalin has been shown to improve all forms of insomnia and lead to reduced functional impairment and improved quality of life."

Answered by AI

Clinical Trials for Pregabalin

Image of Baylor College of Medicine in Houston, United States.

Stepped Care Treatment for Anxiety

7 - 17
All Sexes
Houston, TX
Childhood anxiety disorders (CAD) are common and impairing. Family based cognitive behavioral therapy (CBT) is efficacious in treating CAD. Yet, many children do not receive care due to barriers such as limited provider availably, high treatment costs, and constrained family resources (e.g., time). To combat these barriers, other treatment methods have been developed. The stepped care treatment models maximize resources by providing low-intensity, low-cost interventions as a first time treatment, while stepping up care for those needing more intensive treatment. Specifically, a stepped care model for CAD that begins with a parent-focus intervention has great promise to deliver efficacious and cost-effective treatment without having to engage the child. While stepped care approaches show promise in treating CAD with comparable efficacy to standard CBT, there remains a large research-to-practice gap. The stepped care model for CAD that begins with a parent-focused intervention has yet been explored, and very little is known about intervention mediators that explain mechanisms of change. This research is being done to improve the reach and quality of services using a stepped care model, offering an affordable and practical solution to the widespread gap in youth mental health care.
Waitlist Available
Has No Placebo
Baylor College of Medicine
Image of Shirley Ryan AbilityLab in Chicago, United States.

Paired Associative Stimulation + Locomotor Training for Spinal Cord Injury

18 - 75
All Sexes
Chicago, IL
Locomotor recovery is one of the most important goals of individuals with spinal cord injury (SCI). Ambulatory deficits severely impact daily functions resulting in lower quality of life for people living with paralysis due to SCI. Although studies have shown that locomotor training improves locomotor function in people with chronic SCI, the benefits remain limited. Our overall hypothesis is that we can engage additional descending motor pathways, such as the reticulospinal tract (RST), to improve locomotor function in humans with chronic incomplete SCI. In this study we propose to test the effects of a novel intervention that uses repeated paired loud auditory and electrical stimulation of muscle afferents combined with locomotor training on walking speed and voluntary muscle strength.
Phase 1 & 2
Waitlist Available
Shirley Ryan AbilityLabDalia De Santis, PhD
Have you considered Pregabalin clinical trials? We made a collection of clinical trials featuring Pregabalin, we think they might fit your search criteria.Go to Trials
Image of University of British Columbia in Kelowna, Canada.

Pain Management Tools for Spinal Cord Injury

18+
All Sexes
Kelowna, Canada
Brief Summary The goal of this clinical trial is to evaluate whether a neuroscience-informed, peer-led self-management program can promote behavior change and reduce pain interference in adults with spinal cord injury (SCI) and chronic pain. The primary aim is to support participants in developing practical, sustainable strategies for managing chronic pain through education, reflection, and consistent application of self-management tools. The program is designed to shift participants from passive recipients of care to active agents in their own pain management process. Chronic pain is highly prevalent among individuals with SCI, and many report that traditional treatments - primarily pharmacological - provide limited relief and are accompanied by significant side effects. There is a growing need for accessible, non-clinical interventions that empower individuals to manage pain based on the latest neuroscience and behavior change principles. Solving SCI Pain intervention is a 7-week, multi-component program grounded in brain-based pain science, neuroplasticity, and behavior change models. The main questions it aims to answer are: * Does the intervention lead to meaningful changes in behavior that support pain self-management? * Does it reduce pain interference in everyday life? Participants will: * Attend three 2-hour group education sessions focused on the neuroscience of pain, the role of fear-avoidance, pain-related beliefs, and body-based self-regulation tools (e.g., movement, Graston, percussion massage, and red light therapy). * Participate in four individual coaching sessions (up to 1 hour each) designed to help them reflect on their experiences, overcome barriers, and integrate the tools into daily life. * Follow individualized coaching recommendations and provided resources to support each participant's unique engagement with cognitive and body-based tools over the 7-week period, including light journaling, goal setting, and guided reflections. * Complete brief check-ins every four days to monitor progress, engagement, and self-reported outcomes. Group and coaching sessions will be recorded and transcribed to support qualitative analysis, allowing researchers to understand how the intervention is experienced and delivered. This will help refine the program for future implementation and scaling. The study prioritizes accessibility, relevance, and peer involvement to address the real-world needs of individuals living with SCI and chronic pain.
Waitlist Available
Has No Placebo
University of British ColumbiaKathleen A Martin Ginis, PhD
Image of Cognixion HQ in Santa Barbara, United States.

Cognixion + Apple Vision Pro for ALS

18+
All Sexes
Santa Barbara, CA
The goal of this study is refine the usability of a BCI capable communication platform. The study will take place in the United States area and will enroll up to 10 participants with late stage ALS, traumatic brain injury (TBI) or spinal cord injury (SCI) that have assistive communication and computer control needs. Each subject will receive an integrated Cognixion + Apple Vision Pro device that includes an augmented reality brain computer interface and associated communication software. The study duration is 3-4 months for each participant. The key questions that will be addressed in this study are: 1. Identify the ability of individuals with target indications to use the integrated Cognixion-Apple Vision Pro system to communicate effectively. 2. Identify the ability of such individuals to learn to use BCI, ET-BCI and other modalities, and to measure their progress over time. 3. Identify the effectiveness of the different forms of input supported by the combined Cognixion-Apple Vision Pro system (BCI, eye-tracking) in allowing such individuals to communicate and have agency. 4. Identify how input such as BCI can be optimized to suit the needs of individuals (e.g., specific frequencies that work best for an individual, SNR with different frequencies, number of targets, length of recording for each frequency) and improve overall usability. 5. Identify the extent to which personalization through a large language model (LLM) affects communication. 6. Identify the appropriate capabilities to enable through an agentic communication interface. Key measures include: ITR - information transfer rate SUS - system usability scale
Waitlist Available
Has No Placebo
Cognixion HQChristopher J UllrichCognixion
Image of Medical University of South Carolina in Charleston, United States.

Motor Evoked Potential Conditioning for Spinal Cord Injury

18+
All Sexes
Charleston, SC
The purpose of this research study is to examine the effect of a brain stimulation training to improve the function of brain-spinal cord- muscle connections. Because brain-to-muscle pathways are very important in our movement control, restoring function of these pathways may improve movement problems after injuries. Spinal cord injury causes damage to the brain-to-muscle connection. However, when the injury is "incomplete", there is a possibility that some of the brain-to-muscle pathways are still connected and may be trained to improve movement function. For examining brain-to-muscle pathways, investigators use a transcranial magnetic stimulator. Investigators hope that the results of this research study will help us develop new treatments for people who have movement disabilities. This study will require about 42 visits over the first 14 weeks, and another 6 visits over an additional 3 months. Each visit will take about 1 ½ hours.
Recruiting
Has No Placebo
Medical University of South CarolinaAiko Thompson, PhD
Have you considered Pregabalin clinical trials? We made a collection of clinical trials featuring Pregabalin, we think they might fit your search criteria.Go to Trials
Have you considered Pregabalin clinical trials? We made a collection of clinical trials featuring Pregabalin, we think they might fit your search criteria.Go to Trials
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