TURN-IT exercise program for Parkinson's Disease

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Oregon Health & Science University, Portland, ORParkinson's DiseaseTURN-IT exercise program - Behavioral
Eligibility
55 - 85
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether an exercise program can improve turning ability in people with Parkinson's Disease.

Treatment Effectiveness

Study Objectives

2 Primary · 12 Secondary · Reporting Duration: 52 weeks

52 weeks
Change in prospective fall rate
6 weeks
Change in Activities-Specific Balance Confidence Scale
Change in Cadence
Change in Clinical Global Impression of Change
Change in Falls Efficacy Scale International
Change in Parkinson's Disease Questionnaire-39
Change in Patient Global Impression of Change
Change in Stride length
Change in Stride velocity
Change in Turn Angle
Change in Unified Parkinson's Disease Rating Scale, Part III
Change in angle of foot at heel strike
Change in cadence
Change in clinical global impression of change
Change in double support time
Change in duration of longest walking bout per day
Change in lateral trunk range
Change in mini-Balance Evaluation Systems Test
Change in number of bouts of walking and steps per day
Change in number of steps to complete a turn
Change in number of turns per hour
Change in patient global impression of change
Change in stride length
Change in stride velocity
Change in turn angle amplitude
Change in turn duration
Change in turn peak velocity
Change in turn trunk jerk
Change in variability in number of steps to complete a turn
Change in variability of angle of foot at heel strike
Change in variability of double-support time
Variability of double-support time

Trial Safety

Trial Design

3 Treatment Groups

No Intervention Control Group
1 of 3
Turning Boot Camp Group
1 of 3
TURN-IT group
1 of 3

Active Control

Experimental Treatment

60 Total Participants · 3 Treatment Groups

Primary Treatment: TURN-IT exercise program · No Placebo Group · N/A

Turning Boot Camp Group
Behavioral
Experimental Group · 1 Intervention: Turning Boot Camp exercise program · Intervention Types: Behavioral
TURN-IT group
Behavioral
Experimental Group · 1 Intervention: TURN-IT exercise program · Intervention Types: Behavioral
No Intervention Control GroupNoIntervention Group · 1 Intervention: No Intervention Control Group · Intervention Types:

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 52 weeks

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor
904 Previous Clinical Trials
6,830,581 Total Patients Enrolled
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH
1,840 Previous Clinical Trials
2,162,760 Total Patients Enrolled
Fay Horak, PhD, PTPrincipal InvestigatorOregon Health and Science University

Eligibility Criteria

Age 55 - 85 · All Participants · 6 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have moderate to severe Parkinson's disease, classified as stages II-IV by the Hoehn & Yahr scale.
You have fallen at least once in the past year and reported it.

Frequently Asked Questions

Are there age restrictions for participants in this particular research endeavor?

"According to the prerequisites for this research, patient eligibility necessitates a minimum age of 55 and an upper limit of 85." - Anonymous Online Contributor

Unverified Answer

Is there currently an opportunity for participants to join this medical experiment?

"Affirmative. Information from clinicaltrials.gov suggests that the trial was first listed on September 13th 2021 and has been actively recruiting since then. The study seeks to recruit 60 individuals across a single site." - Anonymous Online Contributor

Unverified Answer

What results is this experiment attempting to demonstrate?

"The 6-week evaluation intends to assess the alteration in steps necessary for a turn. Secondary assessments include the fluctuation of double-support time (coefficient of variation), Change in Patient Global Impression of Change (scores range from 1-7, with 1-3 indicating an improvement and 5-7 signifying declining mobility) and finally, change in turn duration (time taken averaged from daily monitoring)." - Anonymous Online Contributor

Unverified Answer

What criteria must potential participants meet to qualify for this clinical experiment?

"This clinical trial is looking to recruit 60 individuals between the ages of 55 and 85 who have been diagnosed with Parkinsons Disease by a qualified neurologist. Moreover, prospective participants must demonstrate bradykinesia alongside at least one other symptom (rest tremor rigidity or balance issues) that are not caused by visual, vestibular, cerebellar or proprioceptive conditions; be responsive to levodopa; display Hoehn & Yahr stages II-IV signs of PD; report having experienced one or more falls in the past 12 months; commit to attending exercise intervention sessions on OHSU campus grounds without altering their" - Anonymous Online Contributor

Unverified Answer

How many individuals have expressed interest in participating in this experiment?

"Affirmative. Clinicaltrials.gov reveals this medical trial is currently recruiting; it was initially posted on September 13th 2021 and last modified on August 23rd 2022. Sixty participants are being accepted from one site only." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.