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Exercise Program for Parkinson's Disease

N/A

Recruiting

Led By Fay Horak, PhD, PT

Research Sponsored by Oregon Health and Science University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis of idiopathic PD from movement disorders neurologist with the United Kingdom Brain Bank criteria of bradykinesia with 1 or more of the following - rest tremor, rigidity, and balance problems not from visual, vestibular, cerebellar or proprioceptive conditions

Hoehn & Yahr stages II-IV

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 52 weeks

Awards & highlights

Study Summary

This trial is testing whether an exercise program can improve turning ability in people with Parkinson's Disease.

Who is the study for?

This trial is for people aged 55-85 with Parkinson's Disease who have fallen in the past year. They must respond to levodopa treatment, be at certain stages of the disease, and can't have other major health issues or recent medication changes. Participants need to commit to attending exercise sessions without altering their medications or exercise habits.Check my eligibility

What is being tested?

The TURN-IT program focuses on improving turning movements in those with Parkinson's by addressing common physical limitations caused by the disease. The study will compare a group doing this special exercise three times a week for six weeks against a control group that does not receive any intervention.See study design

What are the potential side effects?

Since TURN-IT is an exercise program, potential side effects may include muscle soreness, fatigue, and increased risk of falls during practice. However, these are typical responses to physical activity and should be temporary as participants adapt.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have Parkinson's diagnosed by a specialist, with symptoms like slow movement, tremor, stiffness, or balance issues not caused by other conditions.

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My Parkinson's disease is at a moderate to advanced stage.

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I am between 55 and 85 years old.

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I have fallen at least once in the last year.

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My condition improves with levodopa treatment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 52 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~52 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 52 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in variability in number of steps to complete a turn

Secondary outcome measures

Change in Falls Efficacy Scale International

Change in lateral trunk range

Change in number of steps to complete a turn

+7 more

Other outcome measures

Change in Activities-Specific Balance Confidence Scale

Change in Parkinson's Disease Questionnaire-39

Change in Unified Parkinson's Disease Rating Scale, Part III

+11 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: TURN-IT groupExperimental Treatment1 Intervention

Participants in the treatment group will attend supervised, 1-hour classes, 3 times per week for 6 weeks, one-on-one with the same exercise trainer, overseen by a physical therapist investigator.

Group II: No Intervention Control GroupActive Control1 Intervention

Participants in this group will be tested at baseline and 6 weeks later. They will go about their normal daily life during the 6 week period.

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

Oregon Health and Science UniversityLead Sponsor

973 Previous Clinical Trials

6,845,969 Total Patients Enrolled

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)NIH

1,963 Previous Clinical Trials

2,674,590 Total Patients Enrolled

Fay Horak, PhD, PTPrincipal InvestigatorOregon Health and Science University

Media Library

Turning Boot Camp exercise program Clinical Trial Eligibility Overview. Trial Name: NCT04897256 — N/A

Parkinson's Disease Research Study Groups: No Intervention Control Group, TURN-IT group

Parkinson's Disease Clinical Trial 2023: Turning Boot Camp exercise program Highlights & Side Effects. Trial Name: NCT04897256 — N/A

Turning Boot Camp exercise program 2023 Treatment Timeline for Medical Study. Trial Name: NCT04897256 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there age restrictions for participants in this particular research endeavor?

"According to the prerequisites for this research, patient eligibility necessitates a minimum age of 55 and an upper limit of 85."

Answered by AI

Is there currently an opportunity for participants to join this medical experiment?

"Affirmative. Information from clinicaltrials.gov suggests that the trial was first listed on September 13th 2021 and has been actively recruiting since then. The study seeks to recruit 60 individuals across a single site."

Answered by AI

What results is this experiment attempting to demonstrate?

"The 6-week evaluation intends to assess the alteration in steps necessary for a turn. Secondary assessments include the fluctuation of double-support time (coefficient of variation), Change in Patient Global Impression of Change (scores range from 1-7, with 1-3 indicating an improvement and 5-7 signifying declining mobility) and finally, change in turn duration (time taken averaged from daily monitoring)."

Answered by AI

What criteria must potential participants meet to qualify for this clinical experiment?

"This clinical trial is looking to recruit 60 individuals between the ages of 55 and 85 who have been diagnosed with Parkinsons disease by a qualified neurologist. Moreover, prospective participants must demonstrate bradykinesia alongside at least one other symptom (rest tremor rigidity or balance issues) that are not caused by visual, vestibular, cerebellar or proprioceptive conditions; be responsive to levodopa; display Hoehn & Yahr stages II-IV signs of PD; report having experienced one or more falls in the past 12 months; commit to attending exercise intervention sessions on OHSU campus grounds without altering their"

Answered by AI

How many individuals have expressed interest in participating in this experiment?

"Affirmative. Clinicaltrials.gov reveals this medical trial is currently recruiting; it was initially posted on September 13th 2021 and last modified on August 23rd 2022. Sixty participants are being accepted from one site only."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mobility in Daily Life and Falls in Parkinson's Disease: Potential for Rehabilitation

Martina Mancini 2021. "Mobility in Daily Life and Falls in Parkinson's Disease: Potential for Rehabilitation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04897256.

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