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Backward vs Forward Walking Training for Multiple Sclerosis (TRAIN-BW Trial)
N/A
Recruiting
Led By Nora Fritz, PhD
Research Sponsored by Wayne State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
PDDS <6, indicating ability to ambulate with or without an assistive device >/= 50% of the time
Diagnosis of MS
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights
TRAIN-BW Trial Summary
This trial will investigate the feasibility, acceptability and impact of backward walking training compared to forward walking training on motor function and fall risk in persons with multiple sclerosis.
Who is the study for?
This trial is for individuals with multiple sclerosis who have trouble walking or have fallen at least twice in the past six months. They must be able to walk with or without help most of the time and not be in a current MS relapse. People can't join if they have other neurological disorders, can't follow instructions, or have recent orthopedic injuries.Check my eligibility
What is being tested?
The study compares backward walking training (BW) to forward walking training (FW) to see which is better at improving motor function and reducing fall risk in people with multiple sclerosis. It's checking if BW training could be a feasible and acceptable method for these patients.See study design
What are the potential side effects?
Since this trial involves physical exercise interventions rather than medication, side effects may include muscle soreness, fatigue, joint pain, or increased risk of falls during the training sessions.
TRAIN-BW Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I can walk with or without help more than half the time.
Select...
I have been diagnosed with multiple sclerosis (MS).
Select...
I often have trouble walking or have fallen twice or more in the last 6 months.
TRAIN-BW Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 6 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Stepping latency on push-and-release test
Sway during quiet stance
Secondary outcome measures
ABC Scale
Client Satisfaction Questionnaire (CSQ-8)
Forward and Backward Velocity and Double Support Time
+3 moreTRAIN-BW Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: TRAIN-BWExperimental Treatment1 Intervention
1x/week for 8 weeks + home exercise program
Group II: TRAIN-FWActive Control1 Intervention
1x/week for 8 weeks + home exercise program
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Backward Walking Training
2017
N/A
~130
Find a Location
Who is running the clinical trial?
Wayne State UniversityLead Sponsor
307 Previous Clinical Trials
108,383 Total Patients Enrolled
7 Trials studying Multiple Sclerosis
689 Patients Enrolled for Multiple Sclerosis
Nora Fritz, PhDPrincipal Investigator - Wayne State University
Wayne State University
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I can walk with or without help more than half the time.I have had an MS flare-up in the last 30 days.I have a neurological disorder.I have been diagnosed with multiple sclerosis (MS).I can follow instructions related to the study.I have a recent bone injury or disorder.I often have trouble walking or have fallen twice or more in the last 6 months.
Research Study Groups:
This trial has the following groups:- Group 1: TRAIN-FW
- Group 2: TRAIN-BW
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are patient enrollments currently open for this investigation?
"That is correct. Clinicaltrials.gov indicates that this trial, originally posted on the first of January 2020 and last updated on July 25th 2022, is actively recruiting patients with a goal to enrol 90 people at one site."
Answered by AI
How many participants are engaged in this trial?
"Affirmative. Clinicaltrials.gov has information attesting to this medical trial being in the process of recruiting patients. This research project was first made public on January 1st 2020 and recently updated on July 25th 2022, aiming to acquire 90 participants from a single site."
Answered by AI
What is the primary mission of this research endeavor?
"The main objective of this clinical trial, to be measured after 8 weeks, is to assess participants' stepping latency using the push-and-release test. Secondary endpoints for data collection include Client Satisfaction Questionnaire (CSQ-8), ABC Scale balance confidence scores, and a record of falls post intervention period."
Answered by AI
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