Exercise for Anxiety Disorders
What You Need to Know Before You Apply
What is the purpose of this trial?
The overarching objective is to examine the brain-based biological mechanistic pathway by which exercise exerts anxiolytic effects. The investigators will measure brain-derived markers of mitochondrial metabolism (acetyl-L-carnitine \[LAC\]) and inflammation (interleukin-6 \[IL-6\]) using innovative technology to isolate neuronal exosomes.
Who Is on the Research Team?
Kristin Szuhany, PhD
Principal Investigator
NYU Langone Health
Are You a Good Fit for This Trial?
This trial is for sedentary adults aged 18-50 with a primary psychiatric diagnosis of generalized anxiety disorder, social anxiety disorder, or panic disorder. Participants must be capable and willing to provide informed consent.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants complete a 4-week exercise intervention with 150 minutes of moderate intensity exercise per week at home, measured using Fitbits
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Exercise Intervention
Trial Overview
The study investigates how exercise affects brain chemistry related to anxiety. It measures markers like acetyl-L-carnitine and interleukin-6 in the brain using advanced technology to understand exercise's anxiolytic effects.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
All participants will complete the 4-week exercise intervention in which they'll be prescribed 150 minutes of moderate intensity exercise per week at home, which will be measured using Fitbits.
All participants will complete the 4-week exercise intervention in which they'll be prescribed 150 minutes of moderate intensity exercise per week at home, which will be measured using Fitbits.
Find a Clinic Near You
Who Is Running the Clinical Trial?
NYU Langone Health
Lead Sponsor
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