Prazepam

Generalized Anxiety Disorder, Anxiety, Anxiety Disorders + 3 more

Treatment

20 Active Studies for Prazepam

What is Prazepam

Prazepam

The Generic name of this drug

Treatment Summary

Prazepam is a type of medication in the benzodiazepine class used to treat anxiety disorders. It is classified as a Schedule IV drug in the United States.

image of different drug pills on a surface

Prazepam Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Prazepam

0

Effectiveness

How Prazepam Affects Patients

Prazepam is a type of drug that is used to reduce anxiety, treat seizures, and help with muscle relaxation. It belongs to a group of drugs called benzodiazepines, which can be addictive if taken for too long or at high doses.

How Prazepam works in the body

Prazepam works by sending signals to the brain to block arousal in areas responsible for cortical and limbic activity. It does this by stimulating receptors that respond to GABA, a neurotransmitter with an inhibitory effect.

When to interrupt dosage

The measure of Prazepam is contingent upon the diagnosed condition, for example Anxiety Disorders, Generalized Anxiety Disorder and Mental disorders. The amount of dosage is reliant upon the approach of delivery featured in the table below.

Condition

Dosage

Administration

Muscle Relaxation

Generalized Anxiety Disorder

Anxiety

Anxiety Disorders

Mental disorders

Therapeutic procedure

Warnings

Prazepam has six contraindications, thus it should not be taken when experiencing any of the situations listed in the table below.

Prazepam Contraindications

Condition

Risk Level

Notes

Liver Failure

Do Not Combine

Pregnancy Trimester, First

Do Not Combine

Obstructive Sleep Apnea (OSA)

Do Not Combine

Myasthenia Gravis

Do Not Combine

Respiratory Insufficiency

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Prazepam may interact with Pulse Frequency

There are 20 known major drug interactions with Prazepam.

Common Prazepam Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Prazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Ethanol

Major

Prazepam may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Methadone

Major

Prazepam may increase the central nervous system depressant (CNS depressant) activities of Methadone.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Prazepam is combined with Oliceridine.

Sodium oxybate

Major

Prazepam may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.

Prazepam Toxicity & Overdose Risk

Overdosing on Diclofenac can cause sleepiness, confusion, and loss of consciousness. It is important to monitor the patient's breathing rate, heart rate, and blood pressure.

image of a doctor in a lab doing drug, clinical research

Prazepam Novel Uses: Which Conditions Have a Clinical Trial Featuring Prazepam?

396 active studies are in progress to examine the potential of Prazepam in alleviating Anxiety Disorders, Generalized Anxiety Disorder and Mental afflictions.

Condition

Clinical Trials

Trial Phases

Generalized Anxiety Disorder

181 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Early Phase 1, Phase 3, Phase 1

Therapeutic procedure

0 Actively Recruiting

Muscle Relaxation

0 Actively Recruiting

Mental disorders

10 Actively Recruiting

Phase 2, Phase 1, Early Phase 1, Phase 4, Not Applicable

Anxiety

0 Actively Recruiting

Anxiety Disorders

53 Actively Recruiting

Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1

Prazepam Reviews: What are patients saying about Prazepam?

5

Patient Review

1/15/2019

Prazepam for Chronic Trouble Sleeping

I was first prescribed this medication in 2011 after my colon cancer diagnosis and subsequent chemotherapy. At that time, my anxiety levels were very high and I couldn't sleep at night. This medication worked wonders for me; just 1.5mg before bed under the tongue did the trick. It's now 2019 and my doctors have taken me off of the medication, saying it's not good for my bones or brain. I haven't been able to sleep properly since going off of it, and they refuse to put me back on it. So I guess I'm screwed.

5

Patient Review

4/5/2022

Prazepam for Chronic Trouble Sleeping

Lorazepam is the only medication that works for me. I tried Ambien, Trazadone, and Doxepin before, but they didn't work and had terrible side effects. Lorazepam helps me throughout the day and allows me to sleep for seven to eight hours at night with no nightmares. Without it, I can only sleep for a few hours.

5

Patient Review

1/15/2019

Prazepam for Chronic Trouble Sleeping

I was first prescribed this medication in 2011 after my colon cancer diagnosis and chemotherapy. At that time, my anxiety levels were very high and I couldn't sleep at night. This medication worked wonders for me; just 1.5mg before bed under the tongue allowed me to finally get some rest. Fast forward to 2019, my doctors have now taken me off the medication because they say it's not good for my bones or brain, but it's been over a month since I stopped taking it and I still can't sleep properly. They refuse to prescribe it to me again, so I guess I'm screwed.

5

Patient Review

4/5/2022

Prazepam for Chronic Trouble Sleeping

Lorazepam is really the only medication that works for me. I tried Ambien, Trazadone, and Doxepin before, but they didn't work and had awful side effects. Lorazepam helps me feel calm throughout the day and I can sleep easily for 7-8 hours at night. There are no negative side effects that I've experienced, just a sense of calmness if you have anxiety.

5

Patient Review

1/15/2019

Prazepam for Chronic Trouble Sleeping

I was first prescribed this medication in 2011 after I had to go through colon cancer and chemo. At that time, my anxiety levels were really high and I couldn't sleep at night. This medication worked very well for me; however, now it is 2019 and my doctors have taken me off of it saying it's not good for my bones or brain. It's been over a month since I've taken it and I still don't sleep right. They won't put me back on it so I guess I'm screwed.

5

Patient Review

4/5/2022

Prazepam for Chronic Trouble Sleeping

Lorazepam is the only medication that has worked for me. I've tried Ambien, Trazadone, and Doxepin in the past, but they not only didn't work but also had terrible side effects. Lorazepam allows me to have a calm day and an easy 7-8 hour sleep at night without any nightmares. Without it, I can only sleep for a few hours.

5

Patient Review

7/18/2022

Prazepam for Mania associated with Bipolar Disorder, Adjunct Treatment

This treatment has been a life-saver for me when it comes to my anxiety and panic attacks.

5

Patient Review

8/21/2020

Prazepam for Anxious

This medicine has been a game-changer for me and my anxiety.

5

Patient Review

8/21/2020

Prazepam for Anxious

This medicine has been a life saver for me and my anxiety.

5

Patient Review

7/18/2022

Prazepam for Mania associated with Bipolar Disorder, Adjunct Treatment

Helps me a lot with my anxiety and panic attacks.

5

Patient Review

8/21/2020

Prazepam for Anxious

This medicine has been a godsend for me and my anxiety. It's helped me immensely and I'm extremely grateful for it.

5

Patient Review

7/18/2022

Prazepam for Mania associated with Bipolar Disorder, Adjunct Treatment

This drug has really helped me to manage my anxiety and panic attacks.

4.3

Patient Review

10/8/2019

Prazepam for Anxious

This drug is effective during the day, but if I take it too close to bedtime I have bad dreams.

4.3

Patient Review

5/12/2019

Prazepam for Anxious

The effectiveness of this drug is largely dependent on the user. If you are taking multiple drugs for the same problem, it will be more difficult to gauge the effectiveness of this treatment. However, if you are not mixing it with other medications, it works much better.

4.3

Patient Review

5/12/2019

Prazepam for Anxious

The drug's effectiveness is impacted by the user; if you're taking multiple drugs for the same condition, it'll be difficult to gauge how well this one works. That being said, on its own it's much more effective.

4.3

Patient Review

5/12/2019

Prazepam for Anxious

The effectiveness of this drug depends on the user. If you are taking multiple drugs for the same problem, it will be harder to tell how effective this drug is. However, if you are not mixing it with other drugs, it works much better.

4.3

Patient Review

10/8/2019

Prazepam for Anxious

It's effective during the day, but if I take it too close to bedtime I have bad dreams.

4.3

Patient Review

10/8/2019

Prazepam for Anxious

This treatment is effective during the day but gives me bad dreams if I take it too close to bedtime.

4

Patient Review

6/5/2022

Prazepam for Anxious

In 2007, I had a stroke. Since then, I've been dealing with anxiety. My doctor put me on an anxiety medication for long-term use, and it has really helped. I only take it as needed, and it's been working great for the past 15 years.

4

Patient Review

6/5/2022

Prazepam for Anxious

In 2007, I had a stroke that left me with anxiety. They prescribed me an antianxiety medication to take long term, plus lorazepam as needed. It's been working great for the past 15 years.

4

Patient Review

6/5/2022

Prazepam for Anxious

In 2007, I had a stroke at 44 years old. It left me with terrible anxiety. So they gave me an antianxiety medication for long term plus lorazepam. It works wonders and I have been on it for 15 years. Just taken as needed.

3.3

Patient Review

4/7/2019

Prazepam for Chronic Trouble Sleeping

I've been taking Lorazepam for three nights now because I have trouble sleeping. However, since starting this medication, I have felt really depressed and miserable. I haven't been able to stop crying. Is this a normal side effect of the medication? Will it go away?

3.3

Patient Review

4/7/2019

Prazepam for Chronic Trouble Sleeping

I've only been taking Lorazepam for a short while now, but I am not enjoying the side effects. I'm feeling really down and out, and it's hard to motivate myself to do anything. Hoping this is just a phase that will pass.

3.3

Patient Review

4/7/2019

Prazepam for Chronic Trouble Sleeping

I've only been taking Lorazepam for a short while to help me sleep, but I'm suddenly feeling really depressed and miserable. I don't know if this is a normal side effect, but it's really affecting my quality of life. Hoping it goes away soon.

2.7

Patient Review

5/18/2022

Prazepam for Anxious

The new Teva brand does not work. I've been using Actavis Watson for years, and they were great. Now that Teva has taken over production, the quality of the tablets has gone downhill significantly.

2.7

Patient Review

5/18/2022

Prazepam for Anxious

The new Teva brand does not work. When compared to other generics on the market, this one falls short. Actavis Watson was good.

2.7

Patient Review

5/18/2022

Prazepam for Anxious

The new Teva brand does not work. I've been taking these for years, and the switch to in-house production has resulted in a drop in quality. The other generics on the market seem to be bad as well.

2.3

Patient Review

4/19/2022

Prazepam for Chronic Trouble Sleeping

I was prescribed 0.5mg before bed, but I didn't feel any effects whatsoever. I'm currently trying 2mg, and while it hasn't helped me sleep yet, I am feeling more relaxed. I'll update this review if anything changes.

2.3

Patient Review

4/19/2022

Prazepam for Chronic Trouble Sleeping

I was prescribed 0.5mg before bed. I didn’t feel anything and it hasn’t helped me asleep at all. currently i’m trying 2mg. so far haven't been able to sleep still but am definitely feeling more relaxed. will update

2.3

Patient Review

6/27/2022

Prazepam for Delirium

I was in a really bad place mentally and this medication just made it worse.

2.3

Patient Review

6/27/2022

Prazepam for Delirium

I was in a bad state of mind and this medication only made it worse.

2.3

Patient Review

4/19/2022

Prazepam for Chronic Trouble Sleeping

I was prescribed 0.5mg of this medication to take before bed, but it didn't make me feel any differently and I still couldn't fall asleep. I'm currently taking 2mg per night and while I still haven't been able to sleep, I am feeling more relaxed overall.

2.3

Patient Review

6/27/2022

Prazepam for Delirium

I was in a terrible state of mind and constantly panicking, which only made it worse.

1.3

Patient Review

1/9/2021

Prazepam for Anxious

I saw no benefits from this treatment.

1.3

Patient Review

1/9/2021

Prazepam for Anxious

This didn't do anything for me, unfortunately. Not sure what to do next.

1.3

Patient Review

1/9/2021

Prazepam for Anxious

I didn't experience any benefits from this treatment.

1

Patient Review

4/18/2019

Prazepam for Anxious

CVS switched to this brand, and I found it to be totally bunk. All the reviews were right—it's ineffective and doesn't work. The company needs to be shut down for fraudulently selling these pills.

1

Patient Review

2/6/2019

Prazepam for Anxious

I had an immediate negative reaction to this medication, which included numbness in my lips and brain freeze. I didn't have any issues with the Actives Phara., so it's clear that there's a problem with Leading Pharma's version specifically.

1

Patient Review

2/6/2019

Prazepam for Anxious

The moment I took this, my lips went numb and it felt like my brain was frozen. The active ingredient in this pharmaceutical really needs to be better regulated.

1

Patient Review

4/18/2019

Prazepam for Anxious

Unfortunately, CVS switched to this brand and I found it did not work at all. It was a total waste of money and time.

1

Patient Review

2/6/2019

Prazepam for Anxious

The Leading Pharma version of this medication caused an immediate and bad reaction in me. My lips went numb and my brain felt like it was freeze-drying. I had no problem with the Actives Phara., so I think there's a quality issue that needs to be addressed.

1

Patient Review

4/18/2019

Prazepam for Anxious

I was very disappointed with this treatment. It was ineffective and didn't work at all, just like all the other reviews said. I think this company is committing fraud by selling these useless pills.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about prazepam

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is prazepam available in the US?

"The therapeutic effects of prazepam are due to N-desmethyl-diazepam, which is its prodrug. Prazepam is no longer available in the United States."

Answered by AI

What are the side effects of prazepam?

"Gastrointestinal : To large a dose may cause nausea and vomiting.

What are the most common side effects of Prazepam?

The most common side effects of Prazepam are clumsiness or sleepiness. Other side effects include drowsiness, dizziness, weakness, muscle incoordination, fatigue, confusion, faintness, talkativeness, restlessness, anxiety, excitement, trembling, muscle spasms, sleeping problems and nightmares."

Answered by AI

Is prazepam the same as diazepam?

"Prazepam shares the same pharmacological properties as diazepam, with the exception of a longer lasting effect. It is indicated for the same purposes as diazepam. The most common synonym for prazepam is centrax."

Answered by AI

Clinical Trials for Prazepam

Have you considered Prazepam clinical trials?

We made a collection of clinical trials featuring Prazepam, we think they might fit your search criteria.
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Image of Fred Hutch/University of Washington Cancer Consortium in Seattle, United States.

Psilocybin Therapy for Anxiety and Depression in Cancer

18 - 85
All Sexes
Seattle, WA

This phase II trial tests the safety, side effects and how well group retreat psilocybin therapy works for the treatment of anxiety and depression in patients with solid tumors that have spread from where they first started (primary site) to other places in the body (metastatic) or with hematologic cancers for which no treatment is currently available (incurable). For patients with metastatic, incurable cancer, unrelieved anxiety and existential distress can cause profound suffering. Psilocybin therapy can relieve anxiety and existential distress by disrupting patterns of thinking that contribute to anxiety and depression. Psilocybin is a substance being studied in the treatment of anxiety or depression in patients with cancer. In this study, a pharmaceutical grade of psilocybin will be used that has been approved by the FDA for research, provided by Filament Health. Psilocybin acts on the brain by resetting the brain's activity and increasing connections between brain regions, particularly those involved in mood regulation and self-perception. In this study psilocybin is combined with structured discussions and reflections that enable patients to have new insights about their situation. In a prior study, group retreat psilocybin therapy was proven to be safe and this study tests a refined dosing regimen for symptoms of anxiety and depression in patients with metastatic solid tumors or incurable hematologic malignancies.

Phase 2
Waitlist Available

Fred Hutch/University of Washington Cancer Consortium

Anthony Back, MD

Image of Wahwala Iyohlogya/Peaceful Means in Pine Ridge, United States.

Lakota Family Acceptance Program for Depression and Anxiety

Any Age
All Sexes
Pine Ridge, SD

The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers. The OPT is specifically focused on acceptability, feasibility, and safety of programming and research protocols. The investigators will also examine pre- to post- changes on outcomes for the sole purposes of making sure scores on measures are changing in the hypothesized direction (e.g., depression scores are going from moderate to minimal as opposed to no change or depression scores increasing). Once enrolled in the study, participants complete a baseline survey. Then participants will engage in LFAP which is an 8-session group intervention; sessions will be scheduled once a week for eight weeks (at 2 hours per session). Participants will complete survey instruments before and immediately after the program sessions, in addition to post-program surveys and an exit interview.

Recruiting
Has No Placebo

Wahwala Iyohlogya/Peaceful Means (+1 Sites)

Katie Edwards, PhD

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD

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We made a collection of clinical trials featuring Prazepam, we think they might fit your search criteria.
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Image of Fort Bend ISD in Sugar Land, United States.

Wellbeing Interventions for Anxiety

10 - 20
All Sexes
Sugar Land, TX

The goal of this clinical trial is to learn if psychology and music based interventions can impact anxiety and overall wellbeing in adolescents enrolled in choral music classes. The main questions it aims to answer are: Do specific psychology and music based breathing interventions impact anxiety and overall wellbeing in adolescents? Do specific psychology and music based performance anxiety reduction interventions impact anxiety and overall wellbeing in adolescents? Do specific psychology and music based emotion regulation interventions impact anxiety and overall wellbeing in adolescents? Researchers will compare results of pre-test data, post-test data, qualitative interviews, and surveys of adult choral directors to see if there is a measurable impact on adolescent anxiety and overall wellbeing. Participants will: * Use box breathing during choral music warm-ups to connect choral breathing to breathing for anxiety reduction * Use "magnify" technique to compare cognitive distortions regarding an upcoming performance that may cause anxiety to the most likely realistic outcome * Use emotion regulation through song lyrics technique to connect lyrics of choral music repertoire to participants experienced emotions

Waitlist Available
Has No Placebo

Fort Bend ISD

Jane Kuehne, PhD

Image of Birmingham VA in Birmingham, United States.

Transcranial Alternating Current Stimulation for Anxiety

19 - 70
All Sexes
Birmingham, AL

Transcranial alternating current stimulation (tACS) in a wearable brain stimulation device that delivers a low intensity, pulsed, alternating current via scalp electrodes. Prior sham-controlled clinical trials have shown the therapeutic effects and safety of tACS for the treatment of anxiety and depression. In addition, tACS is rapid acting and well tolerated. After the device is issued to the patient during an in-office orientation and training session, the tACS device can be safely used by the patient at the convenience of their own home. Up to 40 Veterans under that age of 70 who have clinically significant anxiety will be enrolled in an 8-week open-label trial of Model FW-200 tACS to evaluate feasibility, acceptability, adherence and impact on anxiety, depression, post-traumatic stress disorder (PTSD), sleep and neurocognitive measures. Participants may have a concurrent diagnosis of major depressive disorder (MDD) and/or PTSD.

Recruiting
Has No Placebo

Birmingham VA

Lori Davis, MD

Fisher Wallace Laboratories

Have you considered Prazepam clinical trials?

We made a collection of clinical trials featuring Prazepam, we think they might fit your search criteria.
Go to Trials