Stelazine

Schizophrenia, Alzheimer's Disease, Agitation + 2 more
Treatment
2 FDA approvals
20 Active Studies for Stelazine

What is Stelazine

TrifluoperazineThe Generic name of this drug
Treatment SummaryProchlorperazine is a medication used to treat psychotic symptoms (such as hallucinations and delusions) and to reduce nausea and vomiting. It is a type of phenothiazine, similar to the drug chlorpromazine, and works by blocking certain types of receptors in the brain.
Trifluoperazine Hydrochlorideis the brand name
image of different drug pills on a surface
Stelazine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Trifluoperazine Hydrochloride
Trifluoperazine
1981
36

Approved as Treatment by the FDA

Trifluoperazine, otherwise called Trifluoperazine Hydrochloride, is approved by the FDA for 2 uses such as Anxiety and Schizophrenia .
Anxiety
Helps manage acute non-psychotic Anxiety
Schizophrenia
Helps manage Schizophrenia

Effectiveness

How Stelazine Affects PatientsTrifluoperazine is a type of drug used to treat schizophrenia and other mental health conditions. It has not been found to be helpful in treating behavioral issues in people with intellectual disabilities.
How Stelazine works in the bodyTrifluoperazine affects the chemical balance in the brain by blocking certain dopamine receptors. It also decreases the release of hormones from the hypothalamus and pituitary glands, which can affect your metabolism, body temperature, alertness, blood pressure, and vomiting.

When to interrupt dosage

The quantity of Stelazine is subject to the diagnosed affliction, such as Agitation, Anxiety and Alzheimer's Disease. The dosage changes, contingent upon the delivery technique (e.g. Tablet, film coated - Oral or Oral) detailed in the table beneath.
Condition
Dosage
Administration
Alzheimer's Disease
1.0 mg, , 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 1.18 mg, 2.36 mg, 5.9 mg, 11.8 mg, 23.6 mg, 10.0 mg/mL, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral
Schizophrenia
1.0 mg, , 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 1.18 mg, 2.36 mg, 5.9 mg, 11.8 mg, 23.6 mg, 10.0 mg/mL, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral
Agitation
1.0 mg, , 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 1.18 mg, 2.36 mg, 5.9 mg, 11.8 mg, 23.6 mg, 10.0 mg/mL, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral
Schizophrenia
1.0 mg, , 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 1.18 mg, 2.36 mg, 5.9 mg, 11.8 mg, 23.6 mg, 10.0 mg/mL, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral
Anxiety
1.0 mg, , 2.0 mg, 5.0 mg, 10.0 mg, 20.0 mg, 1.18 mg, 2.36 mg, 5.9 mg, 11.8 mg, 23.6 mg, 10.0 mg/mL, 1.0 mg/mL
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral

Warnings

Stelazine has five contraindications and should not be administered when suffering from any of the conditions laid out in the table below.Stelazine Contraindications
Condition
Risk Level
Notes
Coma
Do Not Combine
preexisting liver damage
Do Not Combine
Bone Marrow
Do Not Combine
greatly depression
Do Not Combine
existing blood dyscrasias
Do Not Combine
There are 20 known major drug interactions with Stelazine.
Common Stelazine Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Trifluoperazine may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Trifluoperazine may increase the antipsychotic activities of Amisulpride.
Aripiprazole
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Stelazine Toxicity & Overdose RiskThe symptoms of an overdose on Atenolol may include agitation, loss of consciousness, seizures, difficulty breathing or swallowing, dry mouth, excessive drowsiness, fever, blocked intestines, abnormal heart rate, low blood pressure, and restlessness.

Stelazine Novel Uses: Which Conditions Have a Clinical Trial Featuring Stelazine?

453 active studies are being conducted to appraise the effectiveness of Stelazine in treating Anxiety, Agitation and Schizophrenic symptoms.
Condition
Clinical Trials
Trial Phases
Schizophrenia
110 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Alzheimer's Disease
137 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Schizophrenia
33 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Agitation
6 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Anxiety
0 Actively Recruiting

Stelazine Reviews: What are patients saying about Stelazine?

5Patient Review
6/19/2010
Stelazine for Mental Disorder with Loss of Normal Personality & Reality
This medication has been a life-saver for me. It's allowed me to think clearly and be myself again.
5Patient Review
9/27/2018
Stelazine for Mental Disorder with Loss of Normal Personality & Reality
This treatment was great! It helped me a lot.
5Patient Review
3/15/2010
Stelazine for Schizophrenia
Olanzapine 10mgs a day Mirtazapine Zopiclone 15 mgs nocte
4Patient Review
1/20/2011
Stelazine for Mental Disorder with Loss of Normal Personality & Reality
Stelazine 4mg was really effective when other treatments didn't work for my bipolar disorder. I don't love the side effects (tremors and loss of libido) but they're manageable.
4Patient Review
9/13/2012
Stelazine for Anxious
This drug was effective for me.
View All Reviews

Patient Q&A Section about stelazine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the drug Stelazine used for?

"It can also reduce unwanted/uncontrolled movements (such as twitching, fidgeting, muscle stiffness).

Trifluoperazine is used for treating mental/mood disorders such as schizophrenia and psychotic disorders. It can help patients think more clearly, feel less nervous, and take part in everyday life. Trifluoperazine can also reduce aggressive behavior, the desire to hurt oneself/others, and unwanted/uncontrolled movements (such as twitching, fidgeting, and muscle stiffness)."

Answered by AI

How long can you take Stelazine?

"Stelazine (trifluoperazine) should not be used to treat non-psychotic anxiety at doses higher than 6 mg per day or for longer than 12 weeks. Higher doses or longer intervals of use may cause persistent tardive dyskinesia."

Answered by AI

Why is Stelazine discontinued?

"Trifluoperazine can cause extrapyramidal side effects, which are abnormal muscle contractions, difficulty breathing and swallowing, and neck spasms."

Answered by AI

Is Stelazine still available?

"Stelazine is no longer available as a brand-name medication. It can only be found in generic form."

Answered by AI

Clinical Trials for Stelazine

Have you considered Stelazine clinical trials? We made a collection of clinical trials featuring Stelazine, we think they might fit your search criteria.
Have you considered Stelazine clinical trials? We made a collection of clinical trials featuring Stelazine, we think they might fit your search criteria.
Have you considered Stelazine clinical trials? We made a collection of clinical trials featuring Stelazine, we think they might fit your search criteria.
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