What is Stelazine
TrifluoperazineThe Generic name of this drug
Treatment SummaryProchlorperazine is a medication used to treat psychotic symptoms (such as hallucinations and delusions) and to reduce nausea and vomiting. It is a type of phenothiazine, similar to the drug chlorpromazine, and works by blocking certain types of receptors in the brain.
Trifluoperazine Hydrochlorideis the brand name
Stelazine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Trifluoperazine Hydrochloride
Trifluoperazine
1981
36
Approved as Treatment by the FDA
Trifluoperazine, otherwise called Trifluoperazine Hydrochloride, is approved by the FDA for 2 uses such as Anxiety and Schizophrenia .Anxiety
Helps manage acute non-psychotic Anxiety
Schizophrenia
Helps manage Schizophrenia
Effectiveness
How Stelazine Affects PatientsTrifluoperazine is a type of drug used to treat schizophrenia and other mental health conditions. It has not been found to be helpful in treating behavioral issues in people with intellectual disabilities.
How Stelazine works in the bodyTrifluoperazine affects the chemical balance in the brain by blocking certain dopamine receptors. It also decreases the release of hormones from the hypothalamus and pituitary glands, which can affect your metabolism, body temperature, alertness, blood pressure, and vomiting.
When to interrupt dosage
The quantity of Stelazine is subject to the diagnosed affliction, such as Agitation, Anxiety and Alzheimer's Disease. The dosage changes, contingent upon the delivery technique (e.g. Tablet, film coated - Oral or Oral) detailed in the table beneath.Condition
Dosage
Administration
Anxiety
, 5.0 mg, 10.0 mg/mL, 1.0 mg/mL, 2.0 mg, 1.0 mg, 10.0 mg, 5.9 mg, 1.18 mg, 2.36 mg, 11.8 mg, 23.6 mg, 20.0 mg
Tablet, film coated - Oral, Oral, Tablet - Oral, , Tablet, Tablet, film coated, Syrup - Oral, Syrup
Schizophrenia
, 5.0 mg, 10.0 mg/mL, 1.0 mg/mL, 2.0 mg, 1.0 mg, 10.0 mg, 5.9 mg, 1.18 mg, 2.36 mg, 11.8 mg, 23.6 mg, 20.0 mg
Tablet, film coated - Oral, Oral, Tablet - Oral, , Tablet, Tablet, film coated, Syrup - Oral, Syrup
Agitation
, 5.0 mg, 10.0 mg/mL, 1.0 mg/mL, 2.0 mg, 1.0 mg, 10.0 mg, 5.9 mg, 1.18 mg, 2.36 mg, 11.8 mg, 23.6 mg, 20.0 mg
Tablet, film coated - Oral, Oral, Tablet - Oral, , Tablet, Tablet, film coated, Syrup - Oral, Syrup
Schizophrenia
, 5.0 mg, 10.0 mg/mL, 1.0 mg/mL, 2.0 mg, 1.0 mg, 10.0 mg, 5.9 mg, 1.18 mg, 2.36 mg, 11.8 mg, 23.6 mg, 20.0 mg
Tablet, film coated - Oral, Oral, Tablet - Oral, , Tablet, Tablet, film coated, Syrup - Oral, Syrup
Alzheimer's Disease
, 5.0 mg, 10.0 mg/mL, 1.0 mg/mL, 2.0 mg, 1.0 mg, 10.0 mg, 5.9 mg, 1.18 mg, 2.36 mg, 11.8 mg, 23.6 mg, 20.0 mg
Tablet, film coated - Oral, Oral, Tablet - Oral, , Tablet, Tablet, film coated, Syrup - Oral, Syrup
Warnings
Stelazine has five contraindications and should not be administered when suffering from any of the conditions laid out in the table below.Stelazine ContraindicationsCondition
Risk Level
Notes
existing blood dyscrasias
Do Not Combine
Comatose
Do Not Combine
greatly depression
Do Not Combine
preexisting liver damage
Do Not Combine
Bone Marrow
Do Not Combine
Common Stelazine Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Trifluoperazine may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Trifluoperazine may increase the antipsychotic activities of Amisulpride.
Aripiprazole
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole.
Aripiprazole lauroxil
Major
Trifluoperazine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Stelazine Toxicity & Overdose RiskThe symptoms of an overdose on Atenolol may include agitation, loss of consciousness, seizures, difficulty breathing or swallowing, dry mouth, excessive drowsiness, fever, blocked intestines, abnormal heart rate, low blood pressure, and restlessness.
Stelazine Novel Uses: Which Conditions Have a Clinical Trial Featuring Stelazine?
453 active studies are being conducted to appraise the effectiveness of Stelazine in treating Anxiety, Agitation and Schizophrenic symptoms.Condition
Clinical Trials
Trial Phases
Schizophrenia
33 Actively Recruiting
Early Phase 1, Not Applicable, Phase 2, Phase 4
Alzheimer's Disease
272 Actively Recruiting
Phase 1, Phase 4, Phase 2, Phase 3, Not Applicable, Early Phase 1
Anxiety
0 Actively Recruiting
Agitation
5 Actively Recruiting
Phase 3, Phase 2
Schizophrenia
190 Actively Recruiting
Not Applicable, Phase 2, Phase 3, Early Phase 1, Phase 4, Phase 1
Stelazine Reviews: What are patients saying about Stelazine?
5Patient Review
6/19/2010 This medication has been a life-saver for me. It's allowed me to think clearly and be myself again.
5Patient Review
9/27/2018 This treatment was great! It helped me a lot.
5Patient Review
3/15/2010 Olanzapine 10mgs a day Mirtazapine Zopiclone 15 mgs nocte
4Patient Review
1/20/2011 Stelazine 4mg was really effective when other treatments didn't work for my bipolar disorder. I don't love the side effects (tremors and loss of libido) but they're manageable.
4Patient Review
9/13/2012 This drug was effective for me.
3Patient Review
7/14/2014 I felt pretty sedated and tired after taking this, and experienced some dizziness.
1Patient Review
7/15/2009 This treatment is ineffective and dangerous. It's like treating asthma with Zyklon B.
1Patient Review
8/21/20081Patient Review
1/9/2010 I was on a 5 mg dose of this drug for 8 years, and then my neurologist put me on Risperdal 2 mg for 18 years. He said that this contributed to my development of Parkinson's disease.
Patient Q&A Section about stelazine
What is the drug Stelazine used for?
"It can also reduce unwanted/uncontrolled movements (such as twitching, fidgeting, muscle stiffness).
Trifluoperazine is used for treating mental/mood disorders such as schizophrenia and psychotic disorders. It can help patients think more clearly, feel less nervous, and take part in everyday life. Trifluoperazine can also reduce aggressive behavior, the desire to hurt oneself/others, and unwanted/uncontrolled movements (such as twitching, fidgeting, and muscle stiffness)." - Anonymous Online Contributor
Unverified Answer
How long can you take Stelazine?
"Stelazine (trifluoperazine) should not be used to treat non-psychotic anxiety at doses higher than 6 mg per day or for longer than 12 weeks. Higher doses or longer intervals of use may cause persistent tardive dyskinesia." - Anonymous Online Contributor
Unverified Answer
Why is Stelazine discontinued?
"Trifluoperazine can cause extrapyramidal side effects, which are abnormal muscle contractions, difficulty breathing and swallowing, and neck spasms." - Anonymous Online Contributor
Unverified Answer
Is Stelazine still available?
"Stelazine is no longer available as a brand-name medication. It can only be found in generic form." - Anonymous Online Contributor
Unverified Answer