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Transcranial MRgFUS for Movement Disorders
Study Summary
This trial will test whether a new MRI-guided procedure can help people with hard-to-treat movement disorders by targeting areas of the brain responsible for the symptoms.
- Tardive Dyskinesia
- Wilson's Disease
- Parkinson's Disease
- Holmes Tremor
- Essential Tremor
- Movement Disorders
- Huntington's Disease
- Dystonia
- Orofacial Dyskinesia
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- You have a history of bleeding inside the brain.You have had a seizure in the past year.You have a low platelet count or a bleeding disorder that could cause problems during or after surgery.People with brain tumors.You have an infection that is not under control.You have had deep brain stimulation (DBS) or a specific type of brain surgery in the past.You have a weakened immune system, such as being HIV positive.People who are between 18 and 85 years old, including both men and women.You have a history of unusual bleeding or blood clotting issues.You have had multiple strokes or a stroke within the past 6 months.You have symptoms like headache, nausea, and vision problems caused by increased pressure inside your head.You cannot or do not want to stay lying down for a long time during treatment.You have a different type of brain disease like multisystem atrophy, progressive supranuclear palsy, dementia with Lewy bodies, or Alzheimer's disease.You have a mental illness that is not well controlled, or you experience psychosis.You have a serious illness that could be life-threatening.You have sleep apnea that has not been treated or controlled.You have unstable heart conditions, recent heart attack, congestive heart failure needing medication, or severe high blood pressure.You have metal devices inside your body that are not safe for MRI scans.You have a movement disorder that has not improved with treatment, as confirmed by a movement disorder specialist.You have tried the standard treatments for movement disorders recommended by a specialist doctor and they didn't work for you.You can tell the doctor how you feel during the ExAblate Neuro treatment.
- Group 1: Transcranial ExAblate System
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What criteria are necessary for a person to qualify for this research endeavor?
"Eligible patients must present with etat marbre and be situated between 18-85 years old. The number of participants currently being recruited is approximately 10 individuals."
Are those over twenty years of age eligible for participation in this research trial?
"This trial is specifically intended for those aged 18 to 85. Those younger than 18 have access to 50 studies, while 623 trials cater to people over the age of 65."
Is this research currently accepting new participants?
"Per the data on clinicaltrials.gov, this investigation is not actively searching for test subjects at present. Initially posted in May of 2015 and last updated in December 2022 - while no longer accepting new participants, 637 other trials are currently welcoming volunteers."
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