What is Haloperidol Lactate
HaloperidolThe Generic name of this drug
Treatment SummaryHaloperidol is a medication used to treat psychotic disorders like schizophrenia. It works by blocking dopamine receptors in the brain, reducing the overproduction of dopamine which is believed to cause these conditions. Haloperidol is generally effective and well-tolerated, and is one of the most commonly used antipsychotic medications worldwide. It is normally prescribed to treat “positive” symptoms of schizophrenia such as hallucinations, hearing voices, and disorganized speech. However, it can also cause side effects such as movement disorders, sedation, weight gain, and prolactin changes. Haloperidol has largely been replaced by newer
Haldolis the brand name
Haloperidol Lactate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Haldol
Haloperidol
1971
300
Approved as Treatment by the FDA
Haloperidol, otherwise known as Haldol, is approved by the FDA for 1 uses which include Gilles de la Tourette's Syndrome .Gilles de la Tourette's Syndrome
Helps manage Gilles de la Tourette's Syndrome
Effectiveness
How Haloperidol Lactate Affects PatientsHaloperidol is an effective treatment for positive symptoms of schizophrenia, such as hearing voices or hallucinations. However, it can also cause serious side effects like movement disorders, sedation, weight gain, and changes in levels of the hormone prolactin. Haloperidol is more likely to cause these side effects than other similar drugs, but also works better for reducing schizophrenia symptoms. It works by affecting dopamine pathways in the brain that control symptoms and side effects. In some cases, haloperidol can cause serious and even potentially fatal conditions like Neuroleptic Malignant Syndrome (NMS), QT-prolongation, and
How Haloperidol Lactate works in the bodyHaloperidol works by blocking dopamine receptors in the brain. It is used for treating psychosis, as the overproduction of dopamine is linked to it. Haloperidol is a strong antagonist of the dopamine receptor D2, mainly in the mesolimbic and mesocortical systems of the brain. It also inhibits the effects of dopamine and increases its turnover. It binds more tightly than dopamine to the D2 receptor. It blocks post-synaptic dopamine (D2) receptors, eliminating dopamine neurotransmission and leading to relief from delusions and hallucinations. Haloperidol also has antiemetic activity and can cause extrapy
When to interrupt dosage
The quantity of Haloperidol Lactate is contingent upon the diagnosed situation, including Palliative Care, aggressive response and phencyclidine. The amount of dosage is outlined in the table below, based on the method of delivery.Condition
Dosage
Administration
severe Hyperactivity
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Severe Disruptive Behaviour Disorders
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Schizophrenia
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Schizophrenia
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Obsessive-Compulsive Disorder
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Palliative Care
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
aggressive reaction
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
phencyclidine
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Delirium
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Gilles de la Tourette's Syndrome
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Huntington Disease
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Nausea
, 2.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 5.0 mg/mL, 1.0 mg, 0.5 mg, 10.0 mg, 20.0 mg, 5.0 mg, 2.0 mg, 1.5 mg, 70.52 mg/mL, 500.0 mg/mL, 141.04 mg/mL
Injection - Intramuscular, , Intramuscular, Injection, Solution - Oral, Injection, solution, Solution - Intramuscular, Liquid, Liquid - Intramuscular, Injection, solution - Intramuscular, Oral, Tablet - Oral, Solution, concentrate, Solution, Tablet, Solution, concentrate - Oral
Warnings
Haloperidol Lactate ContraindicationsCondition
Risk Level
Notes
Mental Depression
Do Not Combine
Parkinson's Disease
Do Not Combine
Asthma
Do Not Combine
Mental Depression
Do Not Combine
Comatose
Do Not Combine
Basal Ganglia Lesions
Do Not Combine
Common Haloperidol Lactate Drug Interactions
Drug Name
Risk Level
Description
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Haloperidol.
Amisulpride
Major
Haloperidol may increase the antipsychotic activities of Amisulpride.
Azelastine
Major
Haloperidol may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cariprazine
Major
The metabolism of Cariprazine can be decreased when combined with Haloperidol.
Elacestrant
Major
The serum concentration of Elacestrant can be increased when it is combined with Haloperidol.
Haloperidol Lactate Toxicity & Overdose RiskThe lowest toxic dose of this drug when taken orally by rats has been found to be 71mg/kg.
Haloperidol Lactate Novel Uses: Which Conditions Have a Clinical Trial Featuring Haloperidol Lactate?
285 active studies are presently investigating the utility of Haloperidol Lactate for the treatment of Obsessive-Compulsive Disorder, Palliative Care and Phencyclidine-related conditions.Condition
Clinical Trials
Trial Phases
Schizophrenia
183 Actively Recruiting
Not Applicable, Phase 3, Phase 2, Early Phase 1, Phase 4, Phase 1
Huntington Disease
4 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Obsessive-Compulsive Disorder
17 Actively Recruiting
Not Applicable, Phase 3, Phase 2
Palliative Care
15 Actively Recruiting
Phase 3, Phase 1, Phase 2, Not Applicable
phencyclidine
0 Actively Recruiting
Gilles de la Tourette's Syndrome
0 Actively Recruiting
aggressive reaction
0 Actively Recruiting
severe Hyperactivity
0 Actively Recruiting
Delirium
43 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 3, Phase 1, Early Phase 1
Nausea
0 Actively Recruiting
Severe Disruptive Behaviour Disorders
0 Actively Recruiting
Schizophrenia
32 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Haloperidol Lactate Reviews: What are patients saying about Haloperidol Lactate?
4.3Patient Review
10/30/2011 I was put on hospice due to cancer and began using this drug. So far, it has given me the best results out of all the others.
2.3Patient Review
4/13/2013 I was so angry after they gave me this shot. It did nothing to calm me down, if anything it made me more mad. I wouldn't recommend it to anyone.
2.3Patient Review
8/26/2009 My daughter is still experiencing halucinations even though she's on a high dosage of the medication.
1Patient Review
2/27/2009 My tourettes symptoms have gotten worse since I started this treatment. I've been having a lot of motor tics and screaming.
Patient Q&A Section about haloperidol lactate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Can Haldol make you lactate?
"For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts.
Despite the fact that many people using this medication don't experience serious side effects, there is still a possibility that haloperidol may increase prolactin levels in the body. This chemical increase can have different effects in males and females. For females, it may cause unwanted breast milk, missed or stopped periods, or difficulty getting pregnant. For males, it may lead to decreased sexual ability, infertility, or enlarged breasts."
Answered by AI
What is haloperidol lactate used for?
"Haloperidol is a psychiatric medication (antipsychotic type) that works by helping to restore the balance of certain natural substances in the brain. Haloperidol also can decrease hallucinations and help you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. Haloperidol is not for use in psychotic conditions related to dementia. Haloperidol may also be used for purposes not listed in this medication guide.
50"
Answered by AI
How long does haloperidol lactate last?
"Haloperidol is a medication that is injected into a muscle usually every 3-4 weeks."
Answered by AI