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What is Delatestryl
Testosterone enanthateThe Generic name of this drug
Treatment SummaryTestosterone enanthate is an injectable medication used to treat low testosterone levels. It was first approved in 1953, and since then millions of prescriptions have been filled for testosterone therapy each year. The majority of these prescriptions are for injectable and topical testosterone products. In 2018, the US FDA approved Antares Pharma Inc.'s Xyosted, a subcutaneous testosterone enanthate product that can be self-administered at home with a single dose, disposable autoinjector. This new formulation eliminates the need for frequent clinic visits, making it more convenient for patients.
Delatestrylis the brand name
Delatestryl Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Delatestryl
Testosterone enanthate
1953
8
Effectiveness
How Delatestryl Affects PatientsTaking testosterone enanthate will cause a dramatic increase in testosterone levels in the body, reaching up to 400% of the normal level within 24 hours of taking the drug. These levels will stay high for 3-5 days after the initial dose. Over time, testosterone enanthate can lead to decreased levels of dihydrotestosterone, PSA, HDL, and FSH, and a slight increase in estradiol. These changes can last up to two weeks after the drug is stopped. There are no known effects on mood or sexual activity due to the presence of testosterone enanthate.
How Delatestryl works in the bodyTestosterone is a hormone found in humans and other vertebrates. It works by attaching to receptors in cells, then either directly or indirectly activating them. It also can be changed into a hormone called dihydrotestosterone (DHT). DHT is more powerful than testosterone and has a 2.5 times stronger effect. Testosterone is responsible for the growth and development of male sex organs, as well as secondary sexual characteristics like facial, chest, and pubic hair. Low levels of testosterone are caused by either defects in the gonads or not enough hormones being released from the hypothalamus.
When to interrupt dosage
The suggested dosage of Delatestryl depends on the recognized condition, for example Hypogonadism, Hypogonadism and Hypergonadotropic Hypogonadism. The amount of dosage fluctuates as per the technique of delivery (e.g. Liquid - Intramuscular or Injection, solution) listed in the table hereunder.Condition
Dosage
Administration
Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Hypergonadotropic Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Hypogonadism
, 200.0 mg/mL, 1000.0 mg/mL, 750.0 mg/mL, 500.0 mg/mL, 100.0 mg/mL
, Intramuscular, Injection, solution - Intramuscular, Injection, solution, Liquid, Liquid - Intramuscular, Solution - Intramuscular, Solution, Injection, Injection - Intramuscular, Subcutaneous, Injection - Subcutaneous
Warnings
Delatestryl has two contraindications. If you are suffering from any of the conditions in the following table, Delatestryl should not be administered.Delatestryl ContraindicationsCondition
Risk Level
Notes
hypogonadal conditions not associated with structural or genetic etiologies
Do Not Combine
Breast Cancer
Do Not Combine
Common Delatestryl Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Testosterone enanthate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Testosterone enanthate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Testosterone enanthate.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Testosterone enanthate.
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Testosterone enanthate.
Delatestryl Toxicity & Overdose RiskTestosterone enanthate has been linked to increased risk of hematoma and tumors in preclinical trials. It is not safe for females, pregnant women, or children and can cause permanent infertility in men. Older adults taking androgens may also experience worsening of their Benign Prostatic Hyperplasia symptoms.
Delatestryl Novel Uses: Which Conditions Have a Clinical Trial Featuring Delatestryl?
Currently, there are 7 active clinical trials assessing the potential of Delatestryl as a treatment for Hypogonadism, Hypogonadism and Hypergonadotropic Hypogonadism.Condition
Clinical Trials
Trial Phases
Hypogonadism
0 Actively Recruiting
Hypergonadotropic Hypogonadism
0 Actively Recruiting
Hypogonadism
8 Actively Recruiting
Phase 1, Phase 4, Phase 2, Not Applicable
Delatestryl Reviews: What are patients saying about Delatestryl?
3Patient Review
10/9/2009 The therapy has done its job but I'm not sure about long-term effects.
2.3Patient Review
10/7/2009 I had more energy the next day after using this, which was great. The only issue I had was not knowing how to properly inject it; as a result, I think some of the hormone went to waste.
Patient Q&A Section about delatestryl
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is Delatestryl used for?
"Delatestryl is a prescription medicine used to treat symptoms of Hypogonadism, Delayed Puberty, and Inoperable Mammary Cancer. Delatestryl may be used alone or with other medications. Androgens is a class of drugs Delatestryl belongs to."
Answered by AI
Is Delatestryl a steroid?
"Testosterone enanthate is a medication used to treat low testosterone levels in men and is also used in hormone therapy for transgender men."
Answered by AI
What is Delatestryl made of?
"The Delatestryl is a 200mg testosterone enanthate solution that is used in sesame oil with a 5mg chlorobutanol preservative. It is sterile and colorless to pale yellow in color."
Answered by AI