Aromatherapy with Essential Oils and Virtual Reality for Prognostic Stage IIA Breast Cancer AJCC v8

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
OHSU Knight Cancer Institute, Portland, OR
Prognostic Stage IIA Breast Cancer AJCC v8+31 More
Aromatherapy with Essential Oils and Virtual Reality - Other
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

This study is evaluating whether a virtual reality forest immersion can improve immune cells in cancer patients.

See full description

Eligible Conditions

  • Prognostic Stage IIA Breast Cancer AJCC v8
  • Stage II Prostate Cancer AJCC v8
  • Anatomic Stage III Breast Cancer AJCC v8
  • Anatomic Stage II Breast Cancer AJCC v8
  • Anatomic Stage IIB Breast Cancer AJCC v8
  • Anatomic Stage 1 Breast Cancer AJCC v8
  • Prognostic Stage IA Breast Cancer AJCC v8
  • Prognostic Stage IIB Breast Cancer AJCC v8
  • Stage IIIA Prostate Cancer AJCC v8
  • Anatomic Stage IIIB Breast Cancer AJCC v8
  • Prognostic Stage III Breast Cancer AJCC v8
  • Prognostic Stage IIIA Breast Cancer AJCC v8
  • Prognostic Stage 2 Breast Cancer AJCC v8
  • Malignant Solid Neoplasms
  • Prognostic Stage IIIB Breast Cancer AJCC v8
  • Stage IIIB Prostate Cancer AJCC v8
  • Prognostic Stage IIIC Breast Cancer AJCC v8
  • Stage I Prostate Cancer AJCC v8
  • Anatomic Stage IA Breast Cancer AJCC v8
  • Anatomic Stage IIIC Breast Cancer AJCC v8
  • Stage IIA Prostate Cancer AJCC v8
  • Stage IIC Prostate Cancer AJCC v8
  • Stage IIB Prostate Cancer AJCC v8
  • Stage III Prostate Cancer AJCC v8
  • Stage IIIC Prostate Cancer AJCC v8
  • Anatomic Stage IB Breast Cancer AJCC v8
  • Prognostic Stage IB Breast Cancer AJCC v8
  • Anatomic Stage IIA Breast Cancer AJCC v8
  • Anatomic Stage IIIA Breast Cancer AJCC v8
  • Prognostic Stage 1 Breast Cancer AJCC v8

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Prognostic Stage IIA Breast Cancer AJCC v8

Study Objectives

This trial is evaluating whether Aromatherapy with Essential Oils and Virtual Reality will improve 1 primary outcome and 1 secondary outcome in patients with Prognostic Stage IIA Breast Cancer AJCC v8. Measurement will happen over the course of Baseline/Day 1.

Day 3
Collecting and analyzing immune system measures while deploying the simulated forest immersion therapy with forest oils
Baseline/Day 1
Virtual reality paired with humidified phytoncides to simulate the forest greenspace immersion (SFIT)

Trial Safety

Safety Progress

1 of 3

Other trials for Prognostic Stage IIA Breast Cancer AJCC v8

Trial Design

1 Treatment Group

Supportive care (SFIT, biospecimen, interview)
1 of 1
Experimental Treatment

This trial requires 25 total participants across 1 different treatment group

This trial involves a single treatment. Aromatherapy With Essential Oils And Virtual Reality is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Supportive care (SFIT, biospecimen, interview)
Other
Patients participate in SFIT, using VR pictures of forest and greenspace, and humidified wood and fragrance oils, over 1 hour. Patients also undergo blood sample collection at baseline and on day 3 or 4 and participate in interviews at baseline and post-treatment.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline and at day 3 or 4
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly baseline and at day 3 or 4 for reporting.

Who is running the study

Principal Investigator
A. M. R. P.
Amy M. Ross Ph.D., Principal Investigator
OHSU Knight Cancer Institute

Closest Location

OHSU Knight Cancer Institute - Portland, OR

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Age >= 18 years. Both men and women and members of all races and ethnic groups will be included
Participants must have histologically or cytologically confirmed hormone receptor positive (HR+) HER2 negative (-) breast cancer or prostate cancer (hormone therapy excepted) who are in Stage I-III with no evidence of metastasis using the Cancer Therapy Evaluation Program (CTEP) Simplified Disease Classification
Criteria for solid tumors: Participants must have measurable disease, defined as at least one lesion that can be accurately measured in at least one dimension (longest diameter to be recorded for non-nodal lesions and short axis for nodal lesions) as >= 20 mm with conventional techniques or as >= 10 mm with spiral computed tomography (CT) scan, magnetic resonance imaging (MRI), or calipers by clinical exam
Participants must have no history of autoimmune disease
Ability to understand and the willingness to sign a written informed consent document

Patient Q&A Section

Does breast cancer run in families?

"Results from a recent clinical trial suggest that both genetic predisposition and environmental factors may play a role in the development of breast cancer in certain families. The increased risk of breast cancer associated with family history, especially in young-onset cases, warrants further investigation from a genetic perspective." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets breast cancer?

"The incidence of breast cancer increases with age. Women ≤40 years have higher incidence rates of breast cancer than women ≥ 50 years. Mammography screening should begin at age 40 years." - Anonymous Online Contributor

Unverified Answer

What are common treatments for breast cancer?

"There are many different treatments for [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) including surgery, radiation therapy, chemotherapy and hormonal therapy. The best treatment depends on the type of cancer and other factors such as age. When breast cancer is detected early, then before any symptoms appear, it can often be treated with surgery alone. Chemotherapy may also be used, but usually after surgery. Radiotherapy is sometimes used after surgery to help destroy remaining cancer cells. If breast cancer is found late, then specific drugs used in chemotherapy may be given. In some cases, hormonal therapy may be prescribed instead of chemotherapy. Hormonal therapy can reduce swelling and pain associated with breast cancer, but does not work against the cancer itself." - Anonymous Online Contributor

Unverified Answer

Have there been other clinical trials involving aromatherapy with essential oils and virtual reality?

"The conclusions from this study suggest that aromatherapy may have a role as an adjuvant therapy for breast cancer patients who undergo surgery. Further studies should be conducted to determine whether and how such an intervention influences quality of life and disease free survival." - Anonymous Online Contributor

Unverified Answer

What are the chances of developing breast cancer?

"Based on the data, the typical woman is at least 1% to 2% likely to develop breast cancer by age 50. If she is a survivor of breast cancer, then the risk of subsequent development of breast cancer is up to 25% after 10 years. This indicates that it is important to look into the possibility of breast cancer unless there are strong indications against doing so. There is no indication that screening recommendations need to be changed. Breast cancer is a very dangerous disease with poor prognosis. Screening mammography will never be cost effective, but it is essential to collect information on family history of breast cancer--especially if the family history does not include any first degree relatives who have had breast cancer." - Anonymous Online Contributor

Unverified Answer

What does aromatherapy with essential oils and virtual reality usually treat?

"Data from a recent study suggest that aromatherapy with essential oils may reduce anxiety and pain during BCT, but no significant difference was found between the study groups in terms of treatment outcome. Data from a recent study of our study show that aromatherapy with essential oils and virtual reality may help decrease pain and anxiety in patients undergoing irradiation. Future investigations will focus on decreasing discomfort caused by ultrashort bursts of intense electromagnetic radiation in addition to the use of aromatherapy and virtual reality." - Anonymous Online Contributor

Unverified Answer

What is the survival rate for breast cancer?

"Survival rates vary widely between different geographic areas. Although survival varies by race and ethnicity, overall survival is highest among women with tumors of smallest size, early stage, and hormone receptor positive status." - Anonymous Online Contributor

Unverified Answer

Does aromatherapy with essential oils and virtual reality improve quality of life for those with breast cancer?

"Multifactorial aromatherapy has demonstrated significant effects in improving QoL scores for women with nonmetastatic breast cancer. This multifactorial intervention may also improve women's perceptions of their QoL. As such, this approach merits further consideration as a method of improving QoL for women with breast cancer." - Anonymous Online Contributor

Unverified Answer

What causes breast cancer?

"Breast cancer is a complex disease involving multiple genetic, epigenetic and environmental factors. The underlying mechanism of breast cancer involves interactions between tumor suppressor genes and oncogenes. The key aspects of breast cancer are that it occurs mainly in post-menopausal women who have had at least one child; usually in women aged 40 to 60 years; and it may be triggered by hormones produced during pregnancy and puberty. The risk of breast cancer increases if additional pregnancies occur before 30 years of age. Many factors influence the likelihood of getting breast cancer later in life such as family history, estrogen receptor status, and the amount of circulating estrogens. The development of breast cancer requires an accumulation of multiple alterations in gene expression and epigenetics." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of breast cancer?

"Although the primary cause of breast cancer remains unclear, we found compelling evidence that breast cancer can result from a combination of factors. This means that prevention is not just based on reducing exposure to environmental risk factors. Rather, the reduction of environmental exposures should be accompanied by strategies aimed at reducing the burden of lifetime exposures to environmental factors that increase the likelihood of breast cancer." - Anonymous Online Contributor

Unverified Answer

Is aromatherapy with essential oils and virtual reality typically used in combination with any other treatments?

"Because of the limited availability of clinical trials, we can only conclude that aromatherapy may be beneficial in both the short term and long term. Although EOs may have a small effect on symptoms in the short term, they appear to provide additional benefits when combined with other forms of treatment, particularly psychological. Further studies are needed to determine if aromatherapy combinations will lead to improved outcomes." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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