CelluJuve Injections for Healthy Volunteers

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Spiderwort Biotechnologies Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to test the safety of CelluJuve®, a new injectable treatment, by observing its effects when injected into the upper arm of healthy volunteers. Researchers seek to ensure the injection's safety and study the skin's response at a microscopic level. Participants should be healthy and free of skin issues or conditions that could affect the study's results. Volunteers must be comfortable receiving injections and undergoing a small skin biopsy (a tiny piece of skin taken for study). As an unphased study, this trial offers participants the opportunity to contribute to groundbreaking research on a novel treatment.

Do I need to stop my current medications for the trial?

The trial does not specify if you need to stop taking your current medications, but it mentions that participants must adhere to medication restrictions during the study. It's best to discuss your specific medications with the study team.

What prior data suggests that CelluJuve® is safe for healthy volunteers?

Research shows that the safety of CelluJuve® remains under study. This device is still in development and has not yet received approval from Health Canada or the U.S. Food and Drug Administration. As a result, its safety and effectiveness for people are not fully known. Health Canada has permitted trials to test CelluJuve®, indicating it has passed some basic safety checks. However, detailed information about potential side effects or how well people tolerate the treatment is not yet available. Since this trial is in the early stages, further information about its safety will be collected.12345

Why are researchers excited about this trial?

Unlike the standard of care for skin rejuvenation, which often includes topical creams and laser treatments, CelluJuve® is unique because it involves injections using a novel formulation. Researchers are excited about CelluJuve® because it potentially offers a more direct approach to rejuvenating skin by targeting deeper layers, which could lead to more noticeable and lasting results. Additionally, the injectable nature of CelluJuve® may allow for a more personalized treatment, focusing on specific areas that need improvement.

What evidence suggests that CelluJuve® injections could be effective?

Research shows that the effectiveness of CelluJuve® in people remains unknown. This treatment is currently being tested in the trial to assess its effectiveness and safety. The trial's main goal is to determine the effects of injecting CelluJuve® into the skin. No clear results or data are available yet on its efficacy. Current studies, including this trial, continue to explore its potential benefits and safety.12467

Are You a Good Fit for This Trial?

Healthy adults aged 30-65, with healthy skin on their non-dominant arm, can join this trial. Women must not be pregnant or breastfeeding and use reliable contraception. People are excluded if they have a history of severe allergies to CelluJuve® components, keloid scarring, significant health conditions that could affect the study or are taking certain medications.

Inclusion Criteria

Signed ICF and Photographic Release
I am between 30 and 65 years old and in good health.
I am a woman who can have children, have a negative pregnancy test, and use birth control.
See 3 more

Exclusion Criteria

Study staff or close relative to study staff (e.g., parents, children, siblings, or spouse)
Known history or evidence of keloid scarring, susceptibility to keloid formation or hypertrophic scarring, or delayed healing activity
Known history of medical or psychiatric conditions that may increase the risk associated with study participation or may interfere with interpretation of study results or compliance of the subject and could make the subject inappropriate for study entry
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive injections of CelluJuve® into the proximal medial aspect of the brachium

1 day
1 visit (in-person)

Biopsy and Analysis

Punch biopsies are taken at 2 weeks, 1 month, and 3 months for histological analysis

3 months
3 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

3 months

What Are the Treatments Tested in This Trial?

Interventions

  • CelluJuve®
Trial Overview The trial is testing CelluJuve®, an injectable treatment administered into the upper arm's skin. Participants will receive microbolus injections in one arm and undergo a small biopsy to assess safety and changes in tissue structure.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: CelluJuve®Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Spiderwort Biotechnologies Inc.

Lead Sponsor

ethica Clinical Research Inc.

Industry Sponsor

Trials
20
Recruited
1,800+

Citations

Histological Analysis of CelluJuve® Injections in the ...In a clinical study's protocol, the planned outcome measure that is the most important for evaluating the effect of an intervention/treatment.
Spiderwort Biotechnologies Inc. receives Health Canada ITAThe safety and effectiveness of CelluJuve® in humans has not been fully established and will be evaluated in upcoming clinical trials.For ...
Spiderwort Biotechnologies Inc. Announces Status of ...The safety and effectiveness of CelluJuve® in humans has not been established. For more information about Spiderwort Biotechnologies and ...
Histological Analysis of CelluJuve® Injections in the BrachiumData collected at the beginning of a clinical study for all participants and for each arm or comparison group. These data include demographics, such as age ...
CelluJuve Injections for Healthy VolunteersParticipants are monitored for safety and effectiveness after treatment. 3 months. What Are the Treatments Tested in This Trial? Interventions. CelluJuve®.
Spiderwort Biotechnologies Inc. Receives Health Canada ...The safety and effectiveness of CelluJuve® in humans has not been fully established and will be evaluated in upcoming clinical trials. For ...
Spiderwort Biotechnologies Inc. Announces Status of ...Physicians and patients increasingly seek new and innovative options with favorable safety profiles, and these test results position CelluJuve® ...
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