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What is Nandrolone Decanoate
Nandrolone decanoateThe Generic name of this drug
Treatment SummaryNandrolone decanoate, also known as nandrolone caprinate, is a synthetic steroid used to treat anemia caused by kidney problems and to help prevent bone loss in postmenopausal women. The process to make esters of nandrolone was patented in the 1960s. It was found to have a long-lasting action and a strong anabolic effect compared to other similar drugs. Nandrolone decanoate was approved by the FDA in 1962.
Nandrolone Decanoateis the brand name
Nandrolone Decanoate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Nandrolone Decanoate
Nandrolone decanoate
2007
3
Approved as Treatment by the FDA
Nandrolone decanoate, otherwise called Nandrolone Decanoate, is approved by the FDA for 3 uses including Anemia and Osteoporosis .Anemia
Helps manage Chronic renal failure anemia
Osteoporosis
Used in combination with other therapies
Postmenopausal Osteoporosis
Used in combination with other therapies
Effectiveness
How Nandrolone Decanoate Affects PatientsNandrolone decanoate is a type of steroid used to treat anemia caused by kidney problems and to help with bone loss in older adults or postmenopausal women. It is usually taken every 3-4 weeks and, when taken correctly, rarely results in an overdose. People with heart, kidney, or liver issues should be warned of potential risks before taking this drug.
How Nandrolone Decanoate works in the bodyNandrolone decanoate is broken down into nandrolone in the body. It then binds to cells through receptor-mediated endocytosis and interacts with the androgen receptor. This interaction causes the androgen receptor to enter the nucleus and activate various signals that regulate the transcription of DNA. Androgens can also interact with transcription factors, which can help regulate cell activity.
When to interrupt dosage
The measure of Nandrolone Decanoate is contingent upon the determined disorder, including Postmenopausal Osteoporosis, Anemia and Osteoporosis. The dose will differ as per the method of delivery (e.g. Injection - Intramuscular or Intramuscular) listed in the table below.Condition
Dosage
Administration
Osteoporosis
, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular
Postmenopausal Osteoporosis
, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular
Anemia
, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL
, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular
Warnings
Nandrolone Decanoate ContraindicationsCondition
Risk Level
Notes
Hypercalcemia
Do Not Combine
Breast Cancer
Do Not Combine
Nephrosis
Do Not Combine
Acute Glomerulonephritis
Do Not Combine
Common Nandrolone Decanoate Drug Interactions
Drug Name
Risk Level
Description
2,4-thiazolidinedione
Minor
Nandrolone decanoate may increase the hypoglycemic activities of 2,4-thiazolidinedione.
AICA ribonucleotide
Minor
Nandrolone decanoate may increase the hypoglycemic activities of AICA ribonucleotide.
AMG-222
Minor
Nandrolone decanoate may increase the hypoglycemic activities of AMG-222.
Acarbose
Minor
Nandrolone decanoate may increase the hypoglycemic activities of Acarbose.
Acetohexamide
Minor
Nandrolone decanoate may increase the hypoglycemic activities of Acetohexamide.
Nandrolone Decanoate Toxicity & Overdose RiskOverdosing on nandrolone decanoate can cause a range of side effects, including decreased testosterone and sperm production, decreased libido and erectile dysfunction in men, and irregular menstrual cycles in women. It can also lead to mental and emotional issues, heart problems, and liver damage. Treatment for overdose should focus on relieving symptoms and providing supportive care. In mice, the lowest toxic dose of nandrolone decanoate has been found to be greater than 566mg/kg.
Nandrolone Decanoate Novel Uses: Which Conditions Have a Clinical Trial Featuring Nandrolone Decanoate?
Currently, there are 4 active studies investigating the potential of Nandrolone Decanoate to mitigate Osteoporosis, Postmenopausal Osteoporosis and Anemia.Condition
Clinical Trials
Trial Phases
Postmenopausal Osteoporosis
3 Actively Recruiting
Not Applicable, Phase 4
Osteoporosis
0 Actively Recruiting
Anemia
0 Actively Recruiting
Patient Q&A Section about nandrolone decanoate
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is nandrolone good for building muscle?
"Nandrolone can help increase muscle mass and reduce components of metabolic syndrome. Additionally, it may aid in the healing of joint injuries."
Answered by AI
Does nandrolone decanoate increase testosterone?
"Nandrolone decanoate suppresses testosterone levels in a similar way to other AAS. A dosage of 100 mg/week has been found to decrease testosterone levels by 57% after 6 weeks of treatment, and a dosage of 300 mg/week decreases levels by 70%."
Answered by AI
What is nandrolone used for in bodybuilding?
"Nandrolone decanoate is an anabolic steroid that is designed to slowly increase muscle mass over time. It does this by promoting nitrogen retention in the muscles, which leads to an increase in muscle size. Additionally, it provides relief from joint pain by promoting collagen synthesis and enhancing bone mineralization."
Answered by AI
What is nandrolone decanoate used for?
"Nandrolone decanoate is an anabolic steroid that is used to treat anemia of renal insufficiency and osteoporosis. It is also known as nandrolone caprinate."
Answered by AI