Nandrolone Decanoate

Osteoporosis, Postmenopausal, Osteoporosis, Anemia

Treatment

6 FDA approvals

0 Active Studies for Nandrolone Decanoate

Treatment for

Osteoporosis, Postmenopausal

What is Nandrolone Decanoate

Nandrolone decanoateThe Generic name of this drug

Treatment SummaryNandrolone decanoate, also known as nandrolone caprinate, is a synthetic steroid used to treat anemia caused by kidney problems and to help prevent bone loss in postmenopausal women. The process to make esters of nandrolone was patented in the 1960s. It was found to have a long-lasting action and a strong anabolic effect compared to other similar drugs. Nandrolone decanoate was approved by the FDA in 1962.

Nandrolone Decanoateis the brand name

image of different drug pills on a surface

Nandrolone Decanoate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Nandrolone Decanoate

Nandrolone decanoate

2007

Approved as Treatment by the FDA

Nandrolone decanoate, otherwise called Nandrolone Decanoate, is approved by the FDA for 6 uses including Osteoporosis (Senile) and Postmenopausal Osteoporosis .

Osteoporosis (Senile)

Used in combination with other therapies

Postmenopausal Osteoporosis

Used in combination with other therapies

Chronic renal failure anemia

Helps manage Chronic renal failure anemia

Osteoporosis

Used in combination with other therapies

Osteoporosis, Postmenopausal

Used in combination with other therapies

Anemia

Helps manage Chronic renal failure anemia

Effectiveness

How Nandrolone Decanoate Affects PatientsNandrolone decanoate is a type of steroid used to treat anemia caused by kidney problems and to help with bone loss in older adults or postmenopausal women. It is usually taken every 3-4 weeks and, when taken correctly, rarely results in an overdose. People with heart, kidney, or liver issues should be warned of potential risks before taking this drug.

How Nandrolone Decanoate works in the bodyNandrolone decanoate is broken down into nandrolone in the body. It then binds to cells through receptor-mediated endocytosis and interacts with the androgen receptor. This interaction causes the androgen receptor to enter the nucleus and activate various signals that regulate the transcription of DNA. Androgens can also interact with transcription factors, which can help regulate cell activity.

When to interrupt dosage

The measure of Nandrolone Decanoate is contingent upon the determined disorder, including Postmenopausal Osteoporosis, Anemia and Osteoporosis. The dose will differ as per the method of delivery (e.g. Injection - Intramuscular or Intramuscular) listed in the table below.

Condition

Dosage

Administration

Osteoporosis, Postmenopausal

, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL

, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular

Osteoporosis

, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL

, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular

Anemia

, 200.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL

, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Liquid, Liquid - Intramuscular, Solution, Solution - Intramuscular, Injection, Injection - Intramuscular

Warnings

Nandrolone Decanoate Contraindications

Condition

Risk Level

Notes

Hypercalcemia

Do Not Combine

Breast Cancer

Do Not Combine

Nephrosis

Do Not Combine

Acute Glomerulonephritis

Do Not Combine

There are 20 known major drug interactions with Nandrolone Decanoate.

Common Nandrolone Decanoate Drug Interactions

Drug Name

Risk Level

Description

2,4-thiazolidinedione

Minor

Nandrolone decanoate may increase the hypoglycemic activities of 2,4-thiazolidinedione.

AICA ribonucleotide

Minor

Nandrolone decanoate may increase the hypoglycemic activities of AICA ribonucleotide.

AMG-222

Minor

Nandrolone decanoate may increase the hypoglycemic activities of AMG-222.

Acarbose

Minor

Nandrolone decanoate may increase the hypoglycemic activities of Acarbose.

Acetohexamide

Minor

Nandrolone decanoate may increase the hypoglycemic activities of Acetohexamide.

Nandrolone Decanoate Toxicity & Overdose RiskOverdosing on nandrolone decanoate can cause a range of side effects, including decreased testosterone and sperm production, decreased libido and erectile dysfunction in men, and irregular menstrual cycles in women. It can also lead to mental and emotional issues, heart problems, and liver damage. Treatment for overdose should focus on relieving symptoms and providing supportive care. In mice, the lowest toxic dose of nandrolone decanoate has been found to be greater than 566mg/kg.

image of a doctor in a lab doing drug, clinical research

Nandrolone Decanoate Novel Uses: Which Conditions Have a Clinical Trial Featuring Nandrolone Decanoate?

Currently, there are 4 active studies investigating the potential of Nandrolone Decanoate to mitigate Osteoporosis, Postmenopausal Osteoporosis and Anemia.

Condition

Clinical Trials

Trial Phases

Osteoporosis

0 Actively Recruiting

Anemia

0 Actively Recruiting

Osteoporosis, Postmenopausal

0 Actively Recruiting

Patient Q&A Section about nandrolone decanoate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is nandrolone good for building muscle?

"Nandrolone can help increase muscle mass and reduce components of metabolic syndrome. Additionally, it may aid in the healing of joint injuries."

Answered by AI

Does nandrolone decanoate increase testosterone?

"Nandrolone decanoate suppresses testosterone levels in a similar way to other AAS. A dosage of 100 mg/week has been found to decrease testosterone levels by 57% after 6 weeks of treatment, and a dosage of 300 mg/week decreases levels by 70%."

Answered by AI

What is nandrolone used for in bodybuilding?

"Nandrolone decanoate is an anabolic steroid that is designed to slowly increase muscle mass over time. It does this by promoting nitrogen retention in the muscles, which leads to an increase in muscle size. Additionally, it provides relief from joint pain by promoting collagen synthesis and enhancing bone mineralization."

Answered by AI

What is nandrolone decanoate used for?

"Nandrolone decanoate is an anabolic steroid that is used to treat anemia of renal insufficiency and osteoporosis. It is also known as nandrolone caprinate."

Answered by AI