Stem Cell Therapy

ADSC Application for Osteoarthritis

Q: What is the scope of recruitment for this experiment?

Affirmative. Clinicaltrials.gov verifies that this research trial, which was first publicized on November 1st 2015, is actively recruiting for participants. Specifically, 17 patients must be recruited from two separate medical centres.

Q: Are there any vacancies left to join this clinical research?

Affirmative. Accessing clinicaltrials.gov reveals that this medical trial is still recruiting participants, with 17 patients required from two locations since its initial posting on November 1st 2015 and most recent edit on July 1 2021.

Q: Is this experiment limited to seniors or are younger individuals accepted?

This medical trial is only open to adults aged between 18 and 50. For minors and elderly persons, there are 5 different studies for the former group and 17 specific trials for those over 65 years of age.

Q: Am I eligible to partake in this research endeavor?

This medical experiment is accepting a cohort of 17 individuals aged 18 to 50 with an articular cartilage abnormality. In order to qualify, the following conditions must be met: age <a href="https://www.withpower.com/clinical-trials/ra">ra</a>nge between 18 and 50 years; a limited chondral defect (less than 400mm^2) at either the femoral condyle's medial or lateral end; lower limb mechanical alignment of no more than 5 degrees varus or valgus.

UC Health Steadman Hawkins Clinic - Denver Inverness, Denver, CO

ADSC Application +1 moreN/ARecruitingLed by Seth L Sherman, MDResearch Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Must have overall neutral lower limb mechanical alignment (<5 degrees varus or valgus).

Be between 18 and 65 years old

Must not have

Be younger than 18 years old

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upassessed at baseline, 6 months, 12 months, and 24 months post-operatively.

Awards & highlights

No Placebo-Only Group

Study Summary

This trial is testing two different methods for repairing damage to cartilage in the knee. The first, microfracture, is commonly used. The second, which uses stem cells from fat tissue, is being tested to see if it results in better repair.

Eligible Conditions

Osteoarthritis of the Knee

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

Select...

Your legs must be straight and aligned properly.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ assessed at baseline, 6 months, 12 months, and 24 months post-operatively.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~assessed at baseline, 6 months, 12 months, and 24 months post-operatively.

This trial's timeline: 3 weeks for screening, Varies for treatment, and assessed at baseline, 6 months, 12 months, and 24 months post-operatively. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Health Scores on the KOOS Questionnaire

Secondary outcome measures

Activity Level on the Tegner Activity Scale

Cartilage Composition Assessment by MRI Scan

Functionality Scores on the Lysholm Scale

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: ADSC ApplicationExperimental Treatment1 Intervention

Patients undergo an arthroscopic surgical procedure, ADSC application, followed by physical therapy.

Group II: Microfracture ArmActive Control1 Intervention

Patients undergo an arthroscopic surgical procedure, microfracture, followed by physical therapy.

0 / 1Eligibility criteria met

Find a site

Who is running the clinical trial?

Stanford UniversityOTHER

2,258 Previous Clinical Trials

17,273,623 Total Patients Enrolled

16 Trials studying Osteoarthritis

5,042 Patients Enrolled for Osteoarthritis

University of KentuckyOTHER

175 Previous Clinical Trials

223,430 Total Patients Enrolled

1 Trials studying Osteoarthritis

64 Patients Enrolled for Osteoarthritis

University of Colorado, DenverLead Sponsor

1,661 Previous Clinical Trials

1,662,051 Total Patients Enrolled

13 Trials studying Osteoarthritis

837 Patients Enrolled for Osteoarthritis

Seth L Sherman, MDPrincipal Investigator

Stanford University

2 Previous Clinical Trials

49 Total Patients Enrolled

1 Trials studying Osteoarthritis

29 Patients Enrolled for Osteoarthritis

Jason Dragoo, MDPrincipal Investigator

University of Colorado - Anschutz Medical Campus

3 Previous Clinical Trials

198 Total Patients Enrolled

2 Trials studying Osteoarthritis

174 Patients Enrolled for Osteoarthritis

Media Library

ADSC Application (Stem Cell Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT02090140 — N/A

$Osteoarthritis Research Study Groups: ADSC Application, Microfracture Arm$

Osteoarthritis Clinical Trial 2023: ADSC Application Highlights & Side Effects. Trial Name: NCT02090140 — N/A

ADSC Application (Stem Cell Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT02090140 — N/A

Osteoarthritis Patient Testimony for trial: Trial Name: NCT02090140 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the scope of recruitment for this experiment?

"Affirmative. Clinicaltrials.gov verifies that this research trial, which was first publicized on November 1st 2015, is actively recruiting for participants. Specifically, 17 patients must be recruited from two separate medical centres."

Answered by AI

Are there any vacancies left to join this clinical research?

"Affirmative. Accessing clinicaltrials.gov reveals that this medical trial is still recruiting participants, with 17 patients required from two locations since its initial posting on November 1st 2015 and most recent edit on July 1 2021."

Answered by AI

Is this experiment limited to seniors or are younger individuals accepted?

"This medical trial is only open to adults aged between 18 and 50. For minors and elderly persons, there are 5 different studies for the former group and 17 specific trials for those over 65 years of age."

Answered by AI

Am I eligible to partake in this research endeavor?

"This medical experiment is accepting a cohort of 17 individuals aged 18 to 50 with an articular cartilage abnormality. In order to qualify, the following conditions must be met: age range between 18 and 50 years; a limited chondral defect (less than 400mm^2) at either the femoral condyle's medial or lateral end; lower limb mechanical alignment of no more than 5 degrees varus or valgus."

Answered by AI

Who else is applying?

What state do they live in?

California

Washington

What site did they apply to?

Kerlan Jobe Orthopedic Institute

What portion of applicants met pre-screening criteria?

Did not meet criteria

How many prior treatments have patients received?

Why did patients apply to this trial?

I have not tried any drugs or injections. I am looking for natural treatments for osteoarthritis. I’m not looking to take medication or have surgery if at all possible.

Patient

I’ve had PRP on my left knee with good results but nothing on my right knee that is now showing signs of osteoarthritis degeneration. I’d like to try out therapy on my right, untreated knee.

Patient

I know you have an age restriction, that people in their 60s and 70s who are very active are not eligible for knee replacement would find this procedure very powerful for their lifestyle and could keep people active. You may not be able to change this trial, but why don’t we get one going for us older folks .

Patient