Dexedrine

Narcolepsy, Attention Deficit Hyperactivity Disorder
Treatment
2 FDA approvals
20 Active Studies for Dexedrine

What is Dexedrine

DextroamphetamineThe Generic name of this drug
Treatment SummaryDextroamphetamine is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is a type of amphetamine that has been approved by the FDA since 2001.
Dextrostatis the brand name
image of different drug pills on a surface
Dexedrine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dextrostat
Dextroamphetamine
1975
569

Approved as Treatment by the FDA

Dextroamphetamine, also known as Dextrostat, is approved by the FDA for 2 uses such as Narcolepsy and Attention Deficit Hyperactivity Disorder .
Narcolepsy
Helps manage Narcolepsy
Attention Deficit Hyperactivity Disorder
Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Amphetamine

Effectiveness

How Dexedrine Affects PatientsDextroamphetamine is a drug that stimulates the central nervous system and increases blood pressure, improves breathing, and can act as a mild bronchodilator. The exact way it works is not yet known.
How Dexedrine works in the bodyThe exact way that amphetamines work is not known. Dextroamphetamine, however, is known to increase the amount of dopamine in the brain. It does this by blocking the reuptake of dopamine, increasing its release, and stimulating the backward transport of dopamine from synapses in the brain. Recent research suggests that amphetamines may also affect the number of dopamine transporters in the brain.

When to interrupt dosage

The proposed dosage of Dexedrine is contingent upon the recognized condition. The amount additionally fluctuates as per the strategy of administration (e.g. Tablet or Oral) featured in the table beneath.
Condition
Dosage
Administration
Narcolepsy
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule

Warnings

Dexedrine Contraindications
Condition
Risk Level
Notes
Hypertensive disease
Do Not Combine
Drug abuse
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Hyperthyroidism
Do Not Combine
Agitation
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dextroamphetamine may interact with Pulse Frequency
There are 20 known major drug interactions with Dexedrine.
Common Dexedrine Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Dextroamphetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Dextroamphetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Dextroamphetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Dextroamphetamine.
Flecainide
Major
The metabolism of Flecainide can be decreased when combined with Dextroamphetamine.
Dexedrine Toxicity & Overdose RiskResearch in mice has shown that taking dextroamphetamine in large doses can lead to bone deformities, breathing and digestive issues, and low birth weight in babies. Human studies have not been done, so the risk versus benefit of taking the drug while pregnant should be carefully considered. Mothers should avoid taking dextroamphetamine while breastfeeding, as the drug passes into breast milk. The long-term effects of this drug in young children are not known, so it is best to avoid giving dextroamphetamine to children under 3 years old.
image of a doctor in a lab doing drug, clinical research

Dexedrine Novel Uses: Which Conditions Have a Clinical Trial Featuring Dexedrine?

84 active clinical trials are investigating the potential of Dexedrine for treating conditions like Narcolepsy.
Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
65 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 2, Phase 1, Early Phase 1
Narcolepsy
1 Actively Recruiting
Phase 1

Dexedrine Reviews: What are patients saying about Dexedrine?

5Patient Review
6/19/2012
Dexedrine for Attention Deficit Disorder with Hyperactivity
5Patient Review
7/28/2013
Dexedrine for Attention Deficit Disorder with Hyperactivity
5Patient Review
8/30/2013
Dexedrine for Attention Deficit Disorder with Hyperactivity
I lost my wife because she became addicted to my pills. The addiction made her irrational and violent.
5Patient Review
11/13/2013
Dexedrine for Attention Deficit Disorder with Hyperactivity
It's very difficult to obtain this medication because doctors are unwilling to prescribe it for my schizoaffective disorder. That being said, it's the only medication that works for me and without it I'm a danger to myself and others.
5Patient Review
1/10/2015
Dexedrine for Attention Deficit Disorder with Hyperactivity
When all other treatments failed, this one really saved me. I'm so grateful to be alive and well today.
View All Reviews
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Patient Q&A Section about dexedrine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Dexedrine a narcotic?

"DEXEDRINE is classified as a CII drug by the federal government because it has a potential for abuse and can lead to dependence. Keep DEXEDRINE in a safe place to prevent misuse and abuse."

Answered by AI

Do they still prescribe Dexedrine?

"Although Dexedrine is still prescribed, it is not as popular as newer medications for ADHD such as Adderall, Vyvanse, and Mydayis."

Answered by AI

How does Dexedrine make you feel?

"The strongest component in amphetamine, dextroamphetamine, has a stronger effect than amphetamine, promoting focus and making the person who takes it feel energetic, positive, and euphoric."

Answered by AI

What does Dexedrine do to your body?

"It may also help you to organize your tasks and improve listening skills.

Dextroamphetamine can help improve focus and attention by altering the levels of certain chemicals in the brain. It is classified as a stimulant and can also aid in reducing behavioral problems and improve task organization and listening skills."

Answered by AI

Clinical Trials for Dexedrine

Have you considered Dexedrine clinical trials? We made a collection of clinical trials featuring Dexedrine, we think they might fit your search criteria.
Have you considered Dexedrine clinical trials? We made a collection of clinical trials featuring Dexedrine, we think they might fit your search criteria.
Have you considered Dexedrine clinical trials? We made a collection of clinical trials featuring Dexedrine, we think they might fit your search criteria.
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