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What is Dexedrine
DextroamphetamineThe Generic name of this drug
Treatment SummaryDextroamphetamine is a medication used to treat attention deficit hyperactivity disorder (ADHD). It is a type of amphetamine that has been approved by the FDA since 2001.
Dextrostatis the brand name
Dexedrine Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Dextrostat
Dextroamphetamine
1975
569
Approved as Treatment by the FDA
Dextroamphetamine, also known as Dextrostat, is approved by the FDA for 2 uses such as Attention Deficit Hyperactivity Disorder and Narcolepsy .Attention Deficit Hyperactivity Disorder
Used to treat Attention Deficit Hyperactivity Disorder (ADHD) in combination with Amphetamine
Narcolepsy
Helps manage Narcolepsy
Effectiveness
How Dexedrine Affects PatientsDextroamphetamine is a drug that stimulates the central nervous system and increases blood pressure, improves breathing, and can act as a mild bronchodilator. The exact way it works is not yet known.
How Dexedrine works in the bodyThe exact way that amphetamines work is not known. Dextroamphetamine, however, is known to increase the amount of dopamine in the brain. It does this by blocking the reuptake of dopamine, increasing its release, and stimulating the backward transport of dopamine from synapses in the brain. Recent research suggests that amphetamines may also affect the number of dopamine transporters in the brain.
When to interrupt dosage
The proposed dosage of Dexedrine is contingent upon the recognized condition. The amount additionally fluctuates as per the strategy of administration (e.g. Tablet or Oral) featured in the table beneath.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule
Narcolepsy
, 5.0 mg, 10.0 mg, 15.0 mg, 5.0 mg/mL, 2.5 mg, 7.5 mg, 20.0 mg, 30.0 mg, 3.125 mg, 6.25 mg, 9.375 mg, 12.5 mg, 1.875 mg, 1.25 mg, 3.75 mg, 25.0 mg, 18.75 mg, 60.0 mg, 40.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Liquid, Liquid - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Capsule - Oral, Capsule
Warnings
Dexedrine ContraindicationsCondition
Risk Level
Notes
Hypertensive disease
Do Not Combine
Drug abuse
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
advanced arteriosclerosis
Do Not Combine
Hyperthyroidism
Do Not Combine
Agitation
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Dextroamphetamine may interact with Pulse Frequency
Common Dexedrine Drug Interactions
Drug Name
Risk Level
Description
Clonidine
Major
The metabolism of Clonidine can be decreased when combined with Dextroamphetamine.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Dextroamphetamine.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Dextroamphetamine.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Dextroamphetamine.
Flecainide
Major
The metabolism of Flecainide can be decreased when combined with Dextroamphetamine.
Dexedrine Toxicity & Overdose RiskResearch in mice has shown that taking dextroamphetamine in large doses can lead to bone deformities, breathing and digestive issues, and low birth weight in babies. Human studies have not been done, so the risk versus benefit of taking the drug while pregnant should be carefully considered. Mothers should avoid taking dextroamphetamine while breastfeeding, as the drug passes into breast milk. The long-term effects of this drug in young children are not known, so it is best to avoid giving dextroamphetamine to children under 3 years old.
Dexedrine Novel Uses: Which Conditions Have a Clinical Trial Featuring Dexedrine?
84 active clinical trials are investigating the potential of Dexedrine for treating conditions like Narcolepsy.Condition
Clinical Trials
Trial Phases
Narcolepsy
10 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Dexedrine Reviews: What are patients saying about Dexedrine?
5Patient Review
6/19/20125Patient Review
7/28/20135Patient Review
8/30/2013 I lost my wife because she became addicted to my pills. The addiction made her irrational and violent.
5Patient Review
11/13/2013 It's very difficult to obtain this medication because doctors are unwilling to prescribe it for my schizoaffective disorder. That being said, it's the only medication that works for me and without it I'm a danger to myself and others.
5Patient Review
1/10/2015 When all other treatments failed, this one really saved me. I'm so grateful to be alive and well today.
5Patient Review
4/9/2021 My son took this from age 7 to high school and it was a game-changer. He was able to focus and think before acting, which made life much easier for him. I only wish he had chosen to continue taking it into adulthood.
4.7Patient Review
2/25/2014 I'm curious if anyone else takes 30mg twice a day. That's what my doctor prescribed for me and it seems to be working well, but I want to make sure that's a normal dosage.
4.3Patient Review
9/2/2019 This drug has been really helpful for me while studying. It's a shame that it took so long for me to be prescribed this medication.
4.3Patient Review
10/6/2021 This medication has been a total game-changer for me. I no longer feel like I'm in a fog all the time and can actually get up and do what needs to be done. My thoughts are clear and concise for the first time ever.Side effects: rapid HR, sweating, sleep issues if taken late in the day and loss of appetite, but mostly all is under control.
4.3Patient Review
2/6/2021 This medication has helped me a lot with my ADHD. I've seen significant improvements in my focus, memory, impulse control, and mood and energy regulation.
Patient Q&A Section about dexedrine
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Dexedrine a narcotic?
"DEXEDRINE is classified as a CII drug by the federal government because it has a potential for abuse and can lead to dependence. Keep DEXEDRINE in a safe place to prevent misuse and abuse."
Answered by AI
Do they still prescribe Dexedrine?
"Although Dexedrine is still prescribed, it is not as popular as newer medications for ADHD such as Adderall, Vyvanse, and Mydayis."
Answered by AI
How does Dexedrine make you feel?
"The strongest component in amphetamine, dextroamphetamine, has a stronger effect than amphetamine, promoting focus and making the person who takes it feel energetic, positive, and euphoric."
Answered by AI
What does Dexedrine do to your body?
"It may also help you to organize your tasks and improve listening skills.
Dextroamphetamine can help improve focus and attention by altering the levels of certain chemicals in the brain. It is classified as a stimulant and can also aid in reducing behavioral problems and improve task organization and listening skills."
Answered by AI