Rozerem

Insomnia
Treatment
1 FDA approval
1 Active Study for Rozerem

What is Rozerem

RamelteonThe Generic name of this drug
Treatment SummaryRamelteon is a medication used to treat insomnia, especially difficulty falling asleep. It works by targeting the melatonin receptors in the brain to help regulate sleep patterns. Ramelteon is not known to be addictive or abused and has been found to be safe and effective.
Rozeremis the brand name
image of different drug pills on a surface
Rozerem Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Rozerem
Ramelteon
2005
29

Approved as Treatment by the FDA

Ramelteon, also known as Rozerem, is approved by the FDA for 1 uses including Insomnia .
Insomnia
Helps manage Insomnia

Effectiveness

How Rozerem Affects PatientsRamelteon is a drug that helps with sleep problems. It works by imitating the hormone melatonin, which is produced when we sleep and helps to regulate our body's 24-hour "master clock". Ramelteon targets two specific receptors in the brain, called MT<sub>1</sub> and MT<sub>2</sub>, which are responsible for controlling our sleep-wake cycle. It also has a metabolite that is less powerful but circulates in the body at higher levels than the original compound, and it has a slight effect on the 5HT2b receptor.
How Rozerem works in the bodyRamelteon is a medication that helps promote sleep. It works by targeting two types of melatonin receptors, MT1 and MT2, which are associated with sleepiness and sleep onset. It does not target the MT3 receptor, which has a different effect on the body, or any other receptors associated with neurotransmitters, hormones, or opiates.

When to interrupt dosage

The recommended amount of Rozerem is contingent upon the diagnosed condition. The exact dosage is contingent upon the administration approach featured in the table below.
Condition
Dosage
Administration
Insomnia
, 8.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet - Oral, Tablet

Warnings

Rozerem Contraindications
Condition
Risk Level
Notes
Sleep Apnea Syndromes
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Pharmacotherapy
Do Not Combine
Pulse Frequency
Do Not Combine
development of angioedema
Do Not Combine
There are 20 known major drug interactions with Rozerem.
Common Rozerem Drug Interactions
Drug Name
Risk Level
Description
Azelastine
Major
Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Deutetrabenazine
Major
The risk or severity of sedation and somnolence can be increased when Ramelteon is combined with Deutetrabenazine.
Ethanol
Major
Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
Oliceridine
Major
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Ramelteon is combined with Oliceridine.
Sodium oxybate
Major
Ramelteon may increase the central nervous system depressant (CNS depressant) activities of Sodium oxybate.
image of a doctor in a lab doing drug, clinical research

Rozerem Novel Uses: Which Conditions Have a Clinical Trial Featuring Rozerem?

82 current clinical trials are assessing the potential of Rozerem to reduce symptoms of Insomnia.
Condition
Clinical Trials
Trial Phases
Insomnia
1 Actively Recruiting
Not Applicable

Rozerem Reviews: What are patients saying about Rozerem?

5Patient Review
1/3/2019
Rozerem for Chronic Trouble Sleeping
Despite some scary reviews I read, this drug was recommended by my neurologist and it worked great for me. I'm an epileptic and when I can't sleep, I have seizures. Regular melatonin had stopped working for me, so my doctor prescribed this. The first night I took it,I slept like a rock!
5Patient Review
9/7/2022
Rozerem for Chronic Trouble Sleeping
I was pleased with how well this product worked the very first night I took it. It wasn't like Ambien where you just knock out; rather, it helped me fall asleep gently and naturally.
5Patient Review
5/24/2021
Rozerem for Difficulty Falling Asleep
I've been using this treatment nightly for about three weeks now, and it's really helped me get to sleep much faster. I would say it takes effect within minutes of taking it.
4.7Patient Review
1/27/2019
Rozerem for Difficulty Falling Asleep
Rozerem is excellent! It took a few weeks to work as my doctor warned, but it's been amazing. I sleep so well now and feel great the next day with no hangover effects.
4.3Patient Review
10/11/2022
Rozerem for Chronic Trouble Sleeping
I've had chronic insomnia for years, and was only able to find relief when I started taking Rozerem. It's expensive, but worth every penny to finally be able to get a good night's sleep.
View All Reviews
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Patient Q&A Section about rozerem

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Rozerem similar to Ambien?

"Ramelteon is a sleep medication that helps people fall asleep by making it easier to fall asleep. It is not habit-forming and has fewer side effects than other sleep medications like zolpidem (Ambien), but may be more expensive."

Answered by AI

Is Rozerem a good sleeping pill?

"Ramelteon is a safe and effective way to help patients with chronic insomnia fall asleep and stay asleep. It does not have the potential for abuse or dependence that sedative hypnotics have, and is not classified as a controlled substance."

Answered by AI

Is Rozerem the same as melatonin?

"Rozerem is a medication that sends two specific melatonin-like signals to the brain's sleep center, which reduces the alerting signal at the time a person wants to go to sleep. This is in contrast to melatonin, which has widespread effects throughout the body."

Answered by AI

Clinical Trials for Rozerem