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What is Sonata
ZaleplonThe Generic name of this drug
Treatment SummaryZaleplon is a type of sleep aid medication used to treat insomnia. It is a non-benzodiazepine drug, meaning it works by affecting the brain's GABA receptor complex in a way similar to benzodiazepines. Zaleplon is classified as a Schedule IV drug in the United States.
Sonatais the brand name
Sonata Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Sonata
Zaleplon
1999
64
Approved as Treatment by the FDA
Zaleplon, otherwise called Sonata, is approved by the FDA for 1 uses which include Insomnia .Insomnia
Effectiveness
How Sonata Affects PatientsZaleplon is a drug used to treat short-term insomnia. It is not related to benzodiazepines, barbiturates, or other drugs with similar effects. It works by interacting with two different receptors in the brain: the GABA<sub>B</sub>Z receptor, which is responsible for sedative, anxiety-reducing, muscle relaxing, and anticonvulsant effects; and the GABA<sub>A</sub> receptor, which helps with sleep.
How Sonata works in the bodyZaleplon works by affecting the GABA<sub>B</sub>Z receptor chloride channel macromolecular complex. It also binds to a special receptor in the brain, called the omega-1 receptor, which is part of the GABA-A/chloride ion channel receptor complex. This binding helps it to increase the effects of TBPS, a type of chemical.
When to interrupt dosage
The measure of Sonata is contingent upon the indicated situation. The dose fluctuates depending on the method of administration specified in the table below.Condition
Dosage
Administration
Insomnia
, 5.0 mg, 10.0 mg
, Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral
Warnings
There are 20 known major drug interactions with Sonata.Common Sonata Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Zaleplon.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Zaleplon.
Azelastine
Major
Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Zaleplon.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Zaleplon.
Sonata Toxicity & Overdose RiskSide effects of taking ibuprofen may include abdominal discomfort, difficulty remembering things, feeling lightheaded or off balance, feeling sleepy, pain or discomfort in the eyes, headaches, trouble with periods, feeling sick to the stomach, tingling sensations, and feeling weak.
Sonata Novel Uses: Which Conditions Have a Clinical Trial Featuring Sonata?
82 investigations are actively exploring the potential of Sonata to alleviate Insomnia symptoms.Condition
Clinical Trials
Trial Phases
Insomnia
93 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 3, Phase 1, Early Phase 1
Sonata Reviews: What are patients saying about Sonata?
5Patient Review
6/18/2015 Sonata has been a great switch for me from Ambien CR. I'd been taking the latter for eight years, and while it took a couple of nights to get used to Sonata, the quality of sleep is now much better. There's also no morning grogginess which is amazing.
5Patient Review
5/16/2016 Sonata was an amazing insomnia medication. I never felt groggy or hungover the next morning, which has been a problem with other sleep aids I've taken.
5Patient Review
9/10/2019 I had great success with the generic version made by Teva (10 mg, light and dark green capsule). However, when my pharmacy switched to a different manufacturer (navy capsule), I found this new version to be terrible. It's like the company uses caffeine as a filler! I can't take it because it makes me feel wired and I get NO SLEEP. I have gone through withdrawal because I was told that neither the brand name Sonata nor the Teva product is available.
5Patient Review
1/14/2015 Zolpidem is the only thing that has helped me sleep through the night since I was diagnosed with hyperthyroidism. However, you need two 10mg pills to get any sort of effect and you're limited to 30 per month. Bigelow Sweet Dreams tea also helps a bit, but you'll have to get up during the night to use the restroom.
5Patient Review
3/8/2015 Sonata has been an absolute game-changer for me. I was struggling with anxiety and chronic insomnia, often not falling asleep until 4 or 5 a.m., which made it really tough to get up for work in the morning. Over-the-counter medications did nothing for me, and my doctor first prescribed Ambien, but that also seemed to have no effect. Sonata has helped me fall asleep within 30 minutes, and I can't believe what a difference it has made in my life!
4.7Patient Review
7/17/2016 I have a history of waking up in the middle of the night and being unable to fall asleep for a few hours. Sonata has always worked within 15-20 minutes for me and lasts around 3-4 hours. There's never been any sort of grogginess or hangover, which is great.
4.7Patient Review
12/10/2014 I didn't feel any effects from this medication, even when I took twice the recommended dose.
4.3Patient Review
9/12/2016 This treatment is effective.
4Patient Review
4/8/2016 Keep in mind that everyone is different when considering this treatment. It worked great for me, but it could make things worse for someone else.
3.7Patient Review
11/6/2017 I have Parkinson's and had been using AmbienER for years, but it stopped being effective. I switched to Sonata a few weeks ago and at first had trouble sleeping. However, my doctor said that I just needed to give it some time. After a few nights things got better and now I'm sticking with it. It's easier to fall asleep with Sonata and I sleep for 4-6 hours straight. Usually wake up for about 45 minutes but then fall back asleep for another 3 hours. The dreams are also very vivid and weird. Also, it helps if you don't eat for a few hours before taking the pill
3.7Patient Review
1/12/2015 This sleep medication is effective and doesn't have any negative side effects that I've experienced. It also doesn't make me feel groggy the next day, which is a huge plus.
2.3Patient Review
7/25/2015 I tried this for two weeks and saw no results. In fact, it made my sleep worse. I was constantly up and down, unable to sleep for more than half an hour at a time.
1.7Patient Review
11/8/20141Patient Review
1/3/2016 I was told to take half a dose, and if that didn't work, to take the other half. I took one capsule, and four hours later, I was still awake. I took a second capsule and 12 hours later, I was still awake. Do not bother taking this drug!
1Patient Review
1/28/2017 I was really hoping this would work, but unfortunately it didn't do much for me. I'm back to using Ambien, which is more effective but not ideal. If you're struggling with sleep apnea, I wouldn't recommend this drug.
1Patient Review
4/12/2018 This sleep medicine is really not good. I've been struggling to find a good option for over three years, and this was by far the worst reaction I've had. Be very careful if you decide to try it.
1Patient Review
2/18/2018 This drug did not help me sleep at all. I was awake all night and felt very groggy in the morning.
Patient Q&A Section about sonata
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What sonata means?
"A sonata is an instrumental musical composition consisting of three or four movements in contrasting forms and keys."
Answered by AI
What is a sonata used for?
"Sonata is a sedative used to treat insomnia by causing relaxation and helping you fall asleep and stay asleep."
Answered by AI
What is sonata form in classical music?
"Sonata form consists of three sections, where each section represents a central theme or motif. The term "sonata form" refers to a way of structuring a movement within an instrumental piece of music."
Answered by AI
What are the 3 movements of sonata?
"The three basic elements of sonata form are exposition, development, and recapitulation. There may also be an introduction, usually in slow tempo, and a coda, or tailpiece."
Answered by AI