Sonata

Insomnia
Treatment
1 FDA approval
1 Active Study for Sonata

What is Sonata

ZaleplonThe Generic name of this drug
Treatment SummaryZaleplon is a type of sleep aid medication used to treat insomnia. It is a non-benzodiazepine drug, meaning it works by affecting the brain's GABA receptor complex in a way similar to benzodiazepines. Zaleplon is classified as a Schedule IV drug in the United States.
Sonatais the brand name
image of different drug pills on a surface
Sonata Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Sonata
Zaleplon
1999
64

Approved as Treatment by the FDA

Zaleplon, otherwise called Sonata, is approved by the FDA for 1 uses which include Insomnia .
Insomnia

Effectiveness

How Sonata Affects PatientsZaleplon is a drug used to treat short-term insomnia. It is not related to benzodiazepines, barbiturates, or other drugs with similar effects. It works by interacting with two different receptors in the brain: the GABA<sub>B</sub>Z receptor, which is responsible for sedative, anxiety-reducing, muscle relaxing, and anticonvulsant effects; and the GABA<sub>A</sub> receptor, which helps with sleep.
How Sonata works in the bodyZaleplon works by affecting the GABA<sub>B</sub>Z receptor chloride channel macromolecular complex. It also binds to a special receptor in the brain, called the omega-1 receptor, which is part of the GABA-A/chloride ion channel receptor complex. This binding helps it to increase the effects of TBPS, a type of chemical.

When to interrupt dosage

The measure of Sonata is contingent upon the indicated situation. The dose fluctuates depending on the method of administration specified in the table below.
Condition
Dosage
Administration
Insomnia
, 5.0 mg, 10.0 mg
, Oral, Capsule, Capsule - Oral, Capsule, gelatin coated, Capsule, gelatin coated - Oral

Warnings

There are 20 known major drug interactions with Sonata.
Common Sonata Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Zaleplon.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Zaleplon.
Azelastine
Major
Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Zaleplon.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Zaleplon.
Sonata Toxicity & Overdose RiskSide effects of taking ibuprofen may include abdominal discomfort, difficulty remembering things, feeling lightheaded or off balance, feeling sleepy, pain or discomfort in the eyes, headaches, trouble with periods, feeling sick to the stomach, tingling sensations, and feeling weak.
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Sonata Novel Uses: Which Conditions Have a Clinical Trial Featuring Sonata?

82 investigations are actively exploring the potential of Sonata to alleviate Insomnia symptoms.
Condition
Clinical Trials
Trial Phases
Insomnia
1 Actively Recruiting
Not Applicable

Sonata Reviews: What are patients saying about Sonata?

5Patient Review
6/18/2015
Sonata for Chronic Trouble Sleeping
Sonata has been a great switch for me from Ambien CR. I'd been taking the latter for eight years, and while it took a couple of nights to get used to Sonata, the quality of sleep is now much better. There's also no morning grogginess which is amazing.
5Patient Review
5/16/2016
Sonata for Difficulty Falling Asleep
Sonata was an amazing insomnia medication. I never felt groggy or hungover the next morning, which has been a problem with other sleep aids I've taken.
5Patient Review
9/10/2019
Sonata for Difficulty Falling Asleep
I had great success with the generic version made by Teva (10 mg, light and dark green capsule). However, when my pharmacy switched to a different manufacturer (navy capsule), I found this new version to be terrible. It's like the company uses caffeine as a filler! I can't take it because it makes me feel wired and I get NO SLEEP. I have gone through withdrawal because I was told that neither the brand name Sonata nor the Teva product is available.
5Patient Review
1/14/2015
Sonata for Difficulty Falling Asleep
Zolpidem is the only thing that has helped me sleep through the night since I was diagnosed with hyperthyroidism. However, you need two 10mg pills to get any sort of effect and you're limited to 30 per month. Bigelow Sweet Dreams tea also helps a bit, but you'll have to get up during the night to use the restroom.
5Patient Review
3/8/2015
Sonata for Difficulty Falling Asleep
Sonata has been an absolute game-changer for me. I was struggling with anxiety and chronic insomnia, often not falling asleep until 4 or 5 a.m., which made it really tough to get up for work in the morning. Over-the-counter medications did nothing for me, and my doctor first prescribed Ambien, but that also seemed to have no effect. Sonata has helped me fall asleep within 30 minutes, and I can't believe what a difference it has made in my life!
View All Reviews
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Patient Q&A Section about sonata

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What sonata means?

"A sonata is an instrumental musical composition consisting of three or four movements in contrasting forms and keys."

Answered by AI

What is a sonata used for?

"Sonata is a sedative used to treat insomnia by causing relaxation and helping you fall asleep and stay asleep."

Answered by AI

What is sonata form in classical music?

"Sonata form consists of three sections, where each section represents a central theme or motif. The term "sonata form" refers to a way of structuring a movement within an instrumental piece of music."

Answered by AI

What are the 3 movements of sonata?

"The three basic elements of sonata form are exposition, development, and recapitulation. There may also be an introduction, usually in slow tempo, and a coda, or tailpiece."

Answered by AI

Clinical Trials for Sonata