Sonata

Insomnia

Treatment

1 FDA approval

0 Active Studies for Sonata

What is Sonata

Zaleplon

The Generic name of this drug

Treatment Summary

Zaleplon is a type of sleep aid medication used to treat insomnia. It is a non-benzodiazepine drug, meaning it works by affecting the brain's GABA receptor complex in a way similar to benzodiazepines. Zaleplon is classified as a Schedule IV drug in the United States.

Sonata

is the brand name

image of different drug pills on a surface

Sonata Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Sonata

Zaleplon

1999

64

Approved as Treatment by the FDA

Zaleplon, otherwise called Sonata, is approved by the FDA for 1 uses which include Insomnia .

Insomnia

Effectiveness

How Sonata Affects Patients

Zaleplon is a drug used to treat short-term insomnia. It is not related to benzodiazepines, barbiturates, or other drugs with similar effects. It works by interacting with two different receptors in the brain: the GABA<sub>B</sub>Z receptor, which is responsible for sedative, anxiety-reducing, muscle relaxing, and anticonvulsant effects; and the GABA<sub>A</sub> receptor, which helps with sleep.

How Sonata works in the body

Zaleplon works by affecting the GABA<sub>B</sub>Z receptor chloride channel macromolecular complex. It also binds to a special receptor in the brain, called the omega-1 receptor, which is part of the GABA-A/chloride ion channel receptor complex. This binding helps it to increase the effects of TBPS, a type of chemical.

When to interrupt dosage

The measure of Sonata is contingent upon the indicated situation. The dose fluctuates depending on the method of administration specified in the table below.

Condition

Dosage

Administration

Insomnia

, 5.0 mg, 10.0 mg

Capsule, , Oral, Capsule - Oral, Capsule, gelatin coated - Oral, Capsule, gelatin coated

Warnings

There are 20 known major drug interactions with Sonata.

Common Sonata Drug Interactions

Drug Name

Risk Level

Description

Astemizole

Major

The metabolism of Astemizole can be decreased when combined with Zaleplon.

Axitinib

Major

The metabolism of Axitinib can be decreased when combined with Zaleplon.

Azelastine

Major

Zaleplon may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Zaleplon.

Copanlisib

Major

The metabolism of Copanlisib can be decreased when combined with Zaleplon.

Sonata Toxicity & Overdose Risk

Side effects of taking ibuprofen may include abdominal discomfort, difficulty remembering things, feeling lightheaded or off balance, feeling sleepy, pain or discomfort in the eyes, headaches, trouble with periods, feeling sick to the stomach, tingling sensations, and feeling weak.

image of a doctor in a lab doing drug, clinical research

Sonata Novel Uses: Which Conditions Have a Clinical Trial Featuring Sonata?

82 investigations are actively exploring the potential of Sonata to alleviate Insomnia symptoms.

Condition

Clinical Trials

Trial Phases

Insomnia

0 Actively Recruiting

Sonata Reviews: What are patients saying about Sonata?

5

Patient Review

6/18/2015

Sonata for Chronic Trouble Sleeping

Sonata has been a great switch for me from Ambien CR. I'd been taking the latter for eight years, and while it took a couple of nights to get used to Sonata, the quality of sleep is now much better. There's also no morning grogginess which is amazing.

5

Patient Review

5/16/2016

Sonata for Difficulty Falling Asleep

Sonata was an amazing insomnia medication. I never felt groggy or hungover the next morning, which has been a problem with other sleep aids I've taken.

5

Patient Review

9/10/2019

Sonata for Difficulty Falling Asleep

I had great success with the generic version made by Teva (10 mg, light and dark green capsule). However, when my pharmacy switched to a different manufacturer (navy capsule), I found this new version to be terrible. It's like the company uses caffeine as a filler! I can't take it because it makes me feel wired and I get NO SLEEP. I have gone through withdrawal because I was told that neither the brand name Sonata nor the Teva product is available.

5

Patient Review

1/14/2015

Sonata for Difficulty Falling Asleep

Zolpidem is the only thing that has helped me sleep through the night since I was diagnosed with hyperthyroidism. However, you need two 10mg pills to get any sort of effect and you're limited to 30 per month. Bigelow Sweet Dreams tea also helps a bit, but you'll have to get up during the night to use the restroom.

5

Patient Review

3/8/2015

Sonata for Difficulty Falling Asleep

Sonata has been an absolute game-changer for me. I was struggling with anxiety and chronic insomnia, often not falling asleep until 4 or 5 a.m., which made it really tough to get up for work in the morning. Over-the-counter medications did nothing for me, and my doctor first prescribed Ambien, but that also seemed to have no effect. Sonata has helped me fall asleep within 30 minutes, and I can't believe what a difference it has made in my life!

4.7

Patient Review

7/17/2016

Sonata for Insomnia with Middle of the Night Awakening and 4 Hours Sleep Time Remaining

I have a history of waking up in the middle of the night and being unable to fall asleep for a few hours. Sonata has always worked within 15-20 minutes for me and lasts around 3-4 hours. There's never been any sort of grogginess or hangover, which is great.

4.7

Patient Review

12/10/2014

Sonata for Chronic Trouble Sleeping

I didn't feel any effects from this medication, even when I took twice the recommended dose.

4.3

Patient Review

9/12/2016

Sonata for Insomnia with Middle of the Night Awakening and 4 Hours Sleep Time Remaining

This treatment is effective.

4

Patient Review

4/8/2016

Sonata for Chronic Trouble Sleeping

Keep in mind that everyone is different when considering this treatment. It worked great for me, but it could make things worse for someone else.

3.7

Patient Review

11/6/2017

Sonata for Chronic Trouble Sleeping

I have Parkinson's and had been using AmbienER for years, but it stopped being effective. I switched to Sonata a few weeks ago and at first had trouble sleeping. However, my doctor said that I just needed to give it some time. After a few nights things got better and now I'm sticking with it. It's easier to fall asleep with Sonata and I sleep for 4-6 hours straight. Usually wake up for about 45 minutes but then fall back asleep for another 3 hours. The dreams are also very vivid and weird. Also, it helps if you don't eat for a few hours before taking the pill

3.7

Patient Review

1/12/2015

Sonata for Difficulty Falling Asleep

This sleep medication is effective and doesn't have any negative side effects that I've experienced. It also doesn't make me feel groggy the next day, which is a huge plus.

2.3

Patient Review

7/25/2015

Sonata for Chronic Trouble Sleeping

I tried this for two weeks and saw no results. In fact, it made my sleep worse. I was constantly up and down, unable to sleep for more than half an hour at a time.

1.7

Patient Review

11/8/2014

Sonata for Difficulty Falling Asleep

1

Patient Review

1/3/2016

Sonata for Chronic Trouble Sleeping

I was told to take half a dose, and if that didn't work, to take the other half. I took one capsule, and four hours later, I was still awake. I took a second capsule and 12 hours later, I was still awake. Do not bother taking this drug!

1

Patient Review

1/28/2017

Sonata for Chronic Trouble Sleeping

I was really hoping this would work, but unfortunately it didn't do much for me. I'm back to using Ambien, which is more effective but not ideal. If you're struggling with sleep apnea, I wouldn't recommend this drug.

1

Patient Review

4/12/2018

Sonata for Chronic Trouble Sleeping

This sleep medicine is really not good. I've been struggling to find a good option for over three years, and this was by far the worst reaction I've had. Be very careful if you decide to try it.

1

Patient Review

2/18/2018

Sonata for Difficulty Falling Asleep

This drug did not help me sleep at all. I was awake all night and felt very groggy in the morning.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about sonata

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What sonata means?

"A sonata is an instrumental musical composition consisting of three or four movements in contrasting forms and keys."

Answered by AI

What is a sonata used for?

"Sonata is a sedative used to treat insomnia by causing relaxation and helping you fall asleep and stay asleep."

Answered by AI

What is sonata form in classical music?

"Sonata form consists of three sections, where each section represents a central theme or motif. The term "sonata form" refers to a way of structuring a movement within an instrumental piece of music."

Answered by AI

What are the 3 movements of sonata?

"The three basic elements of sonata form are exposition, development, and recapitulation. There may also be an introduction, usually in slow tempo, and a coda, or tailpiece."

Answered by AI