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What is Fastin
PhentermineThe Generic name of this drug
Treatment SummaryPhentermine is a drug used to control weight, and it was first introduced in 1959. It is related to, but not as strong as amphetamines and is classified as a Schedule IV drug, meaning it has a low potential for abuse. Phentermine was initially available as part of a combination drug with other medications, but later it was approved on its own. In 2012, a new combination of phentermine with topiramate was approved, which requires lower doses of phentermine to be effective.
Ionaminis the brand name
Fastin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ionamin
Phentermine
1959
298
Approved as Treatment by the FDA
Phentermine, also known as Ionamin, is approved by the FDA for 2 uses including Regime of weight reduction and Comorbidity .Regime of weight reduction
Comorbidity
Used to treat one related comorbidity in combination with Topiramate
Effectiveness
How Fastin Affects PatientsPhentermine works by suppressing appetite and increasing the amount of energy the body uses while resting. Clinical studies show that people taking phentermine lose an average of 3.6 kilograms in 2-24 weeks compared to those taking a placebo. Even after treatment ends, patients tend to keep the weight off. Phentermine is related to amphetamines, but does not have any of the same stimulating or dangerous effects, like high blood pressure or an irregular heartbeat.
How Fastin works in the bodyPhentermine works by increasing the amount of a chemical called noradrenaline in the brain. Noradrenaline is a kind of hormone that triggers a “fight or flight” response, which suppresses the feeling of hunger and reduces the need for energy. It also has an indirect effect on serotonin, another hormone that helps regulate appetite. Additionally, it is thought that phentermine may inhibit a chemical called neuropeptide Y, which is involved in hunger signals. Finally, it is a weak inhibitor of monoamine oxidase, which may contribute to its effects.
When to interrupt dosage
The recommended dosage of Fastin hinges on the diagnosed circumstance, including Regime of weight reduction, Hyperlipidemia and Type 2 Diabetes. The measure of dosage is contingent upon the technique of administration (e.g. Oral or Tablet) mentioned in the table underneath.Condition
Dosage
Administration
increase in physical activity
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Type 2 Diabetes
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
High Cholesterol
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Regime of weight reduction
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Comorbidity
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Caloric Restriction
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Hypertensive disease
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
BMI >27 kg/m2
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Chronic Weight Management therapy
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 7.5 mg, 11.25 mg, 8.0 mg, 18.8 mg
, Oral, Capsule, Capsule - Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Warnings
Fastin ContraindicationsCondition
Risk Level
Notes
Hyperthyroidism
Do Not Combine
concomitant use or 14 days after discontinuation
Do Not Combine
Agitation
Do Not Combine
Drug abuse
Do Not Combine
Cardiovascular Diseases
Do Not Combine
Open-angle glaucoma
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Phentermine may interact with Pulse Frequency
Common Fastin Drug Interactions
Drug Name
Risk Level
Description
Iobenguane
Major
Phentermine can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methylene blue
Major
Phentermine may increase the serotonergic activities of Methylene blue.
Mirtazapine
Major
Phentermine may increase the serotonergic activities of Mirtazapine.
1-benzylimidazole
Minor
The therapeutic efficacy of 1-benzylimidazole can be decreased when used in combination with Phentermine.
4-Methoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Phentermine is combined with 4-Methoxyamphetamine.
Fastin Toxicity & Overdose RiskThe toxic dose of phentermine in rats is reported to be 151 mg/kg. Overdosing on this drug can cause restlessness, tremors, confusion, hallucinations, fatigue, depression, fast heartbeat, arrhythmias, high or low blood pressure, nausea, vomiting, diarrhea, abdominal cramps, skin problems, insomnia, irritability, hyperactivity, and changes in personality. In severe cases, this can lead to a psychosis-like state. Studies have not been done to determine if phentermine causes cancer or mutations.
Fastin Novel Uses: Which Conditions Have a Clinical Trial Featuring Fastin?
104 active clinical trials are currently being conducted to assess the value of Fastin in the management of Type 2 Diabetes, Weight Loss Regime and Disease.Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
93 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3, Phase 4
Regime of weight reduction
0 Actively Recruiting
Hypertensive disease
0 Actively Recruiting
Caloric Restriction
0 Actively Recruiting
Chronic Weight Management therapy
0 Actively Recruiting
High Cholesterol
21 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Early Phase 1
BMI >27 kg/m2
0 Actively Recruiting
increase in physical activity
0 Actively Recruiting
Comorbidity
0 Actively Recruiting
Fastin Reviews: What are patients saying about Fastin?
5Patient Review
6/6/2010 I had way more energy and didn't crave food as much. I lost 36 pounds in 3 months, but gained it all back after stopping the treatment. It's really effective, but made me dizzy and not want to eat at first.
5Patient Review
6/17/2011 I do not recommend this drug, especially for those who are under the age of 18. I experienced an abnormal heart rate, shakes, and hallucinations.
5Patient Review
9/1/2010 I initially lost 75 pounds and have been able to keep off 60 of those pounds for over a year now.
5Patient Review
2/23/2011 This treatment has helped me a lot. I feel much more motivated and clearheaded now.
5Patient Review
8/9/20095Patient Review
9/10/20095Patient Review
9/10/20095Patient Review
10/15/20094.7Patient Review
12/17/2009 I have been on fasten for two weeks- already lost 8 pounds with no noticeable side effects (just a little dry mouth, but that's easy to fix with water). This drug is wonderful- my goal is to lose 50 pounds and I'm confident that I'll reach it. I also used to have CFS but not anymore! I can stay awake to watch a movie now, which makes me so happy.
4.7Patient Review
2/13/2010 I started taking this medication at the end of August and have since lost 30 pounds. I've been feeling really energetic and motivated to exercise, which has been great!
4.3Patient Review
6/22/2011 I haven't been taking this pill every day as recommended because I get really hungry when I do. Even just taking it 2-3 days in a row makes me ravenous. There are no side effects that I've noticed, which is great, but the hunger is hard to manage. So far I've only been taking it 3 days a week and eating fruit during the day, plus a meal when I get home. In three weeks I've lost at least 8lbs. Does anyone have any suggestions or know if it would work better if taken everyday?
4Patient Review
8/6/20093.7Patient Review
11/17/2011 This medication was effective in reducing my appetite. However, I also experienced an embarrassing side effect that I have not seen listed anywhere else: an inability to urinate. This happened regardless of how much fluids I consumed or how long I waited. If anyone else has had this problem, please let me know.
2.7Patient Review
5/29/2010 I saw the best results when I remembered to take this medication on an empty stomach, though after a few months the effectiveness decreased. The time-released capsules were especially helpful.
Patient Q&A Section about fastin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is phentermine and fastin the same thing?
"Phentermine is an appetite suppressant that is used as a short-term weight loss aid.
The drug Fastin was once a brand name of phentermine, which was manufactured by King Pharmaceuticals. Phentermine is an appetite suppressant that is used to help with short-term weight loss."
Answered by AI
What does fastin mean?
"It is called "diet pills" because it makes dieting easier by suppressing the appetite.
Amphetamines and other psychoactive drugs that help with weight loss by suppressing appetite are colloquially known as "diet pills.""
Answered by AI
What are fastin pills?
"An prescription medication, Fastin, is available to help treat Obesity. Fastin can be used by itself or in combination with other drugs. Classified as a CNS Stimulant, Anorexiant, and Stimulant, Fastin works by affecting the levels of certain neurotransmitters in the brain."
Answered by AI
Is the drug fastin still available?
"Fastin, a brand name drug, is no longer available in the United States. The generic version of the drug is still available, however."
Answered by AI