Foradil

Chronic Obstructive Pulmonary Disease, Exercise-Induced Bronchospasm, Bronchial Asthma + 5 more
Treatment
20 Active Studies for Foradil

What is Foradil

FormoterolThe Generic name of this drug
Treatment SummaryFormoterol is an inhalable medication used to treat COPD and asthma. It works by relaxing the bronchial muscles in the lungs, making it easier to breathe. The effects of this drug can be felt in a few minutes and can last up to 12 hours. Formoterol is available on its own or combined with corticosteroids and/or long-acting muscarinic antagonists. It is prescribed both as a rescue medication and as a maintenance medication.
Foradilis the brand name
Foradil Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Foradil
Formoterol
2001
36

Effectiveness

How Foradil Affects PatientsFormoterol relaxes the muscles in the lungs, allowing more air to flow in and out. It starts to work quickly (2-3 minutes) and provides relief for up to 12 hours. It is important to note that taking formoterol without other medications (like inhaled corticosteroids) can increase the risk of death due to asthma.
How Foradil works in the bodyFormoterol is a long-acting medication that helps to relax the muscles in the airways, making it easier to breathe. It works by targeting beta<sub>2</sub>-adrenergic receptors, which are found in the lungs. It also has some activity on beta<sub>1</sub> and beta<sub>3</sub> receptors found in the heart, but is much more effective at targeting the beta<sub>2</sub> receptors in the lungs. When formoterol binds to these receptors, it stimulates an enzyme called adenylyl cyclase which helps to relax the muscles in

When to interrupt dosage

The prescribed measure of Foradil is dependent upon the diagnosed condition, including Bronchial Asthma, Bronchoconstriction and Asthma. The amount of dosage depends on the technique of delivery (e.g. Solution - Respiratory (inhalation) or Aerosol) detailed in the table below.
Condition
Dosage
Administration
persistent COPD symptoms
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Bronchial Asthma
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Moderate to Severe COPD
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Bronchoconstriction
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Chronic Obstructive Pulmonary Disease
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Exercise-Induced Bronchospasm
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Chronic Obstructive Airway Disease
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)
Asthma
, 0.012 mg, 0.005 mg, 0.0048 mg, 0.0045 mg, 0.012 mg/pump actuation, 0.005 mg/pump actuation, 0.006 mg/pump actuation, 0.0058 mg/pump actuation, 0.02 mg/mL, 0.009 mg
Solution - Respiratory (inhalation), Aerosol, Powder - Respiratory (inhalation), Aerosol, metered - Respiratory (inhalation), Respiratory (inhalation), Aerosol, metered, , Powder, Solution, Powder, metered - Respiratory (inhalation), Powder, metered, Aerosol - Respiratory (inhalation), Capsule, Capsule - Respiratory (inhalation)

Warnings

Foradil has four contraindications and should not be utilized while experiencing any of the conditions presented in the table below.Foradil Contraindications
Condition
Risk Level
Notes
Status Asthmaticus
Do Not Combine
Status Asthmaticus
Do Not Combine
Not being treated with an inhaled corticosteroid
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Formoterol may interact with Toxoplasma Infections
There are 20 known major drug interactions with Foradil.
Common Foradil Drug Interactions
Drug Name
Risk Level
Description
Amoxapine
Major
The metabolism of Amoxapine can be decreased when combined with Formoterol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Formoterol.
Clomipramine
Major
The metabolism of Clomipramine can be decreased when combined with Formoterol.
Cyclophosphamide
Major
The metabolism of Cyclophosphamide can be decreased when combined with Formoterol.
Dacomitinib
Major
The metabolism of Dacomitinib can be decreased when combined with Formoterol.
Foradil Toxicity & Overdose RiskThe lowest toxic dose of formoterol in rats is 3130mg/kg. Overdosing on formoterol can cause symptoms such as chest pain, high or low blood pressure, fast heartbeat, abnormal heart rhythm, anxiety, headache, shaking, and seizures. Lab tests may show low potassium levels, high blood sugar, and an acidic balance in the body. Treatment for overdosing on formoterol should focus on stabilizing the patient and checking the heart rate. A beta-blocker that affects only the heart may be used to reduce the effects of too much adrenaline in the body if necessary.

Foradil Novel Uses: Which Conditions Have a Clinical Trial Featuring Foradil?

251 active studies are currently being conducted to determine the potential of Foradil in alleviating Chronic Obstructive Pulmonary Disease (COPD), Moderate to Severe COPD and Chronic Obstructive Airway Disease.
Condition
Clinical Trials
Trial Phases
Chronic Obstructive Pulmonary Disease
93 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Asthma
157 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Bronchial Asthma
0 Actively Recruiting
Bronchoconstriction
0 Actively Recruiting
Exercise-Induced Bronchospasm
0 Actively Recruiting
Moderate to Severe COPD
0 Actively Recruiting
Chronic Obstructive Airway Disease
5 Actively Recruiting
Phase 3, Not Applicable, Phase 4
persistent COPD symptoms
0 Actively Recruiting

Foradil Reviews: What are patients saying about Foradil?

5Patient Review
4/14/2012
Foradil for Additional Controller Medication for Asthma
This is the only treatment I've found that actually relieves my exercise-induced asthma attacks and symptoms.
5Patient Review
2/19/2011
Foradil for COPD with Chronic Bronchitis
This medication has been a great help for my breathing and emphysema.
5Patient Review
2/5/2011
Foradil for Bronchi Muscle Spasm resulting from COPD
This treatment really allows me to do more than before.
5Patient Review
9/30/2009
Foradil for Asthma
I've used this medication for years without any issues, but recently I started having to use my rescue inhaler more frequently while exercising. I'm hoping it's just a cold or something, but I'm going to talk to my doctor about it.
5Patient Review
5/3/2013
Foradil for Bronchospasm Prevention with COPD
Foradil is more effective than the CCs, in my opinion.
4.7Patient Review
9/28/2012
Foradil for COPD with Chronic Bronchitis
I've been using this product for over 15 years and it's still the best one I've tried. It's like a breath of fresh air.
4.7Patient Review
2/13/2011
Foradil for Asthma
The only drawback of Foradil is the Aerolizer itself; sometimes the capsule doesn't puncture properly. Other than that, this medication has been great for me.
4.3Patient Review
3/12/2013
Foradil for Additional Controller Medication for Asthma
Was going great! I could play tennis and be active without any issues. Suddenly, I got a lung infection which was treated with antibiotics; that cleared up. However, now my blood pressure is low (103/59) and I feel chilled all day. At night, I sweat in bed until morning. Always feel tired.
4.3Patient Review
2/13/2014
Foradil for COPD with Chronic Bronchitis
Foradil has been a great help for my COPD, reducing my need to use an inhaler from every two hours to just once a day. The only downside is that sometimes the capsules are defective and break before I can inhale them, wasting the medication.
4.3Patient Review
8/30/2009
Foradil for Bronchi Muscle Spasm resulting from COPD
I've been using forasil for 18 months as an alternative to advair. I also use asmanex with it, which I got from the V.A.. It works well enough, all things considered.
4Patient Review
5/20/2010
Foradil for Chronic Bronchitis
Foradil has helped me a lot; I'm finally able to be more active and lose weight without worrying about my breathing.
4Patient Review
5/6/2015
Foradil for Asthma
I've had asthma for a long time, and this is the first drug that has helped me prevent it. That said, the delivery system could be better. It's also worth noting that storing the capsules in the fridge helps with the delivery system issue.
4Patient Review
3/16/2010
Foradil for Bronchi Muscle Spasm resulting from COPD
This has been a helpful addition to my treatment regimen.
3.7Patient Review
9/11/2010
Foradil for Additional Controller Medication for Asthma
I've only just started using this medication, but I stopped using "Advir" because it would cause a yeast infection in the back of my throat. Even though I used a mouth wash after I used the inhailer, it wasn't enough to stop the infections. So far, I haven't had any problems with Foradil, but I'm curious to know if other people have experienced anything different.
3.7Patient Review
5/4/2015
Foradil for Bronchospasm Prevention with COPD
I've been taking this medication for two years now and it's been great overall. The only problem I have is with the capsule and how the medicine is delivered. Sometimes the capsule separates and I'm not sure if it delivered the full dose. It would be nice if they could use a system like Anoro Ellipta.
3.7Patient Review
11/8/2013
Foradil for Asthma
The medicine works well, but I've had issues with the capsule delivery system. More often than not, the capsule fails to spin in the cartridge; which is frustrating and prevents me from getting a proper dose.
3Patient Review
11/28/2009
Foradil for Bronchi Muscle Spasm resulting from COPD
I take Foradil Aerolizer 2 times a day. Are there any bad side effects? 12 mcg per capsule. I don't want to trade one problem for another.
1Patient Review
8/17/2009
Foradil for Asthma
I had a disastrous reaction to this medication and had to stop taking it after just two days. I would highly recommend that you consult with your doctor about other options before trying this one.

Patient Q&A Section about foradil

How quickly does foradil work?

"Formoterol should begin to work within 1-3 minutes after use. Those whose asthma is controlled by occasional use of short-acting bronchodilators should not use Formoterol. It is not meant to be used as a "rescue" medication to relieve current asthma symptoms." - Anonymous Online Contributor

Unverified Answer

Why was foradil discontinued?

"The FDA has announced that Foradil Aerolizer, manufactured by Merck, has been discontinued. The decision to discontinue the product is for business reasons and not due to any safety or efficacy concerns." - Anonymous Online Contributor

Unverified Answer

What is Foradil used for?

"Foradil is a medication used to relieve symptoms of COPD, chronic bronchitis, and emphysema. It can be used by itself or with other medicines." - Anonymous Online Contributor

Unverified Answer

What is the generic name for Foradil?

"Foradil Aerolizer is a long-acting bronchodilator that is used to prevent bronchospasm in people with reversible obstructive airways disease, including symptoms of nighttime asthma." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Foradil

Have you considered Foradil clinical trials? We made a collection of clinical trials featuring Foradil, we think they might fit your search criteria.
Have you considered Foradil clinical trials? We made a collection of clinical trials featuring Foradil, we think they might fit your search criteria.
Have you considered Foradil clinical trials? We made a collection of clinical trials featuring Foradil, we think they might fit your search criteria.
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