Trinalin
Treatment
0 Active Studies for Trinalin
What is Trinalin
Azatadine
The Generic name of this drug
Treatment Summary
Pseudoephedrine is a drug found in the ephedra plant, which has been used in Eastern medicine for centuries. It is related to ephedrine, but is much weaker in its effects on the nervous system. Pseudoephedrine was first studied in the West in 1889 and was discovered to have a decongestant effect on dogs in 1927.
Trinalin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Azatadine
0
Effectiveness
How Trinalin Affects Patients
Pseudoephedrine can help reduce congestion by narrowing the blood vessels. It usually works quickly, but if taken in extended-release form the effects last longer. Patients should be aware that it can cause stimulation of the central nervous system.
How Trinalin works in the body
Pseudoephedrine is a drug that works by activating certain receptors in the body. It tightens blood vessels, making it useful for relieving congestion, and can help treat priapism. It also blocks the action of certain neurotransmitters, like norepinephrine and dopamine, and prevents certain proteins from turning on. These effects cause an increase in blood pressure and heart rate, and can help relax the muscles of the rectum.
Warnings
Trinalin has five contraindications, thus it should not be merged with any of the disorders indicated in the table below.
There are 20 known major drug interactions with Trinalin.
Common Trinalin Drug Interactions
Drug Name
Risk Level
Description
Capmatinib
Major
The serum concentration of Capmatinib can be decreased when it is combined with Azatadine.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Azatadine is combined with Hydroxyzine.
Mobocertinib
Major
The risk or severity of QTc prolongation can be increased when Azatadine is combined with Mobocertinib.
Pitolisant
Major
The therapeutic efficacy of Pitolisant can be decreased when used in combination with Azatadine.
Rimegepant
Major
The metabolism of Rimegepant can be increased when combined with Azatadine.
Trinalin Toxicity & Overdose Risk
The lowest toxic dose of pseudoephedrine in rats is 2206mg/kg and 726mg/kg in mice. Symptoms of an overdose may include dizziness, headache, nausea, vomiting, sweating, thirst, rapid heartbeat, chest pain, difficulty urinating, muscle weakness, anxiety, restlessness, insomnia, psychosis, abnormal heart rhythms, shock, seizures, unconsciousness, and difficulty breathing. To treat an overdose, remove any unabsorbed drug and provide supportive care.
Trinalin Reviews: What are patients saying about Trinalin?
5
Patient Review
10/5/2007
Trinalin for Inflammation of the Nose due to an Allergy
Patient Q&A Section about trinalin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How does pseudoephedrine reduce nasal congestion?
"The drug pseudoephedrine constricts blood vessels not just in the nose and sinuses, but throughout the entire body, which can have the effect of shrinking swelling and draining fluids so that breathing becomes easier."
Answered by AI
What is Trinalin used for?
"Azatadine and pseudoephedrine are used together to treat symptoms such as sneezing, itching, watery eyes, and a runny nose that are caused by allergies or the common cold."
Answered by AI
What does pseudoephedrine do?
"Pseudoephedrine is a decongestant that can relieve a blocked or stuffy nose, which is caused by swollen blood vessels in the cavities in your nose (sinuses)."
Answered by AI