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What is Coreg
CarvedilolThe Generic name of this drug
Treatment SummaryCarvedilol is a combination drug used to treat heart failure, left ventricular dysfunction, and high blood pressure. It works by blocking the action of two types of hormones: beta and alpha-1. Carvedilol has been found to be effective in treating moderate cases of hypertension with fewer side effects than higher doses of single drugs. It was approved by the FDA in 1995.
Coregis the brand name
Coreg Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Coreg
Carvedilol
1997
522
Approved as Treatment by the FDA
Carvedilol, commonly known as Coreg, is approved by the FDA for 6 uses such as Heart Attack and Hypesthesia .Heart Attack
Helps manage Myocardial Infarction
Hypesthesia
Helps manage chronic heart failure with reduced ejection fraction (NYHA Class IV)
Hypesthesia
Helps manage chronic heart failure with reduced ejection fraction (NYHA Class III)
Heart failure
Helps manage NYHA Class I or II heart failure
Ventricular Dysfunction, Left
Helps manage LVEF ≤40% Left ventricular dysfunction
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Effectiveness
How Coreg Affects PatientsCarvedilol is a drug used to reduce a rapid heart rate and lower blood pressure. It needs to be taken once a day and is usually given in doses of 10-80mg. It's important to not stop taking carvedilol suddenly, as this can worsen coronary artery disease.
How Coreg works in the bodyCarvedilol reduces heart rate and blood pressure by blocking signals sent to the heart and blood vessels by the sympathetic nervous system. It also has antioxidant properties, which can help prevent cholesterol from building up in the heart.
When to interrupt dosage
The prescribed dosage of Coreg is contingent upon the diagnosed state, including Chronic Stable Angina Pectoris, Ventricular Dysfunction, Left and Hypesthesia. The amount of dosage varies, based on the administration method denoted in the table below.Condition
Dosage
Administration
Heart failure
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypertensive disease
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Ventricular Dysfunction, Left
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Chronic Stable Angina Pectoris
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Atrial Fibrillation
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Heart Attack
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Warnings
Coreg has nine contra-indications and its utilization should be avoided in combination with the situations specified in the table below.Coreg ContraindicationsCondition
Risk Level
Notes
Bronchospasm
Do Not Combine
Bronchial Asthma
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Therapeutic procedure
Do Not Combine
Therapeutic procedure
Do Not Combine
severe bradycardia
Do Not Combine
third degree AV block
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Carvedilol may interact with Pulse Frequency
Common Coreg Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Carvedilol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Carvedilol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Carvedilol.
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Carvedilol.
Acepromazine
Major
Carvedilol may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Coreg Toxicity & Overdose RiskThose who overdose on the drug may have low blood pressure, slow heartbeats, heart problems, and even cardiac arrest. The patient should be placed in a lying position and can be given atropine for slow heartbeats and glucagon with sympathomimetics to support the cardiovascular system.
Coreg Novel Uses: Which Conditions Have a Clinical Trial Featuring Coreg?
253 active clinical trials are being conducted to assess the potential of Coreg in providing relief for Hypesthesia, Heart failure and Hypesthesia.Condition
Clinical Trials
Trial Phases
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Heart Attack
53 Actively Recruiting
Phase 4, Phase 2, Phase 3, Not Applicable, Phase 1, Early Phase 1
Atrial Fibrillation
146 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Heart failure
0 Actively Recruiting
Hypesthesia
5 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1
Hypesthesia
8 Actively Recruiting
Not Applicable, Phase 1
Chronic Stable Angina Pectoris
1 Actively Recruiting
Not Applicable
Ventricular Dysfunction, Left
0 Actively Recruiting
Coreg Reviews: What are patients saying about Coreg?
5Patient Review
3/25/2018 I began taking Coreg at age 58-59. I was prescribed 12.5 mg twice a day, but experienced some side effects in the form of tiredness. This problem was resolved by taking a 20 mg time-released prescription. It's important to note that I only use brand name Coreg; thegeneric version may not be as effective. I also take lisinipril (generic) and an old generic water pill for my blood pressure. The water pill is a big problem because it makes me have to drink more water and avoid salt, but it does bring my blood pressure down well.
5Patient Review
12/17/2019 I've been on this treatment for two decades and it's really kept me alive and well. I would highly recommend it to others in a similar situation as me.
5Patient Review
7/25/2019 Coreg has been a lifesaver for me since I was diagnosed with heart failure post chemotherapy. My dose is low, at 6.25 mg twice a day, but it keeps my blood pressure in check and has helped me manage my symptoms effectively.
5Patient Review
12/17/2019 I've been taking this medication for 20 years now and it's really kept me going. I don't know how I would have fared without it, but I'm grateful that it hasn't caused any organ damage.
5Patient Review
10/14/2017 I had no issues with this treatment. My blood pressure is now more stable than ever.
4.7Patient Review
11/19/2017 Though there are some not-so-fun side effects that come with this treatment, they pale in comparison to how well it's worked for me. I was diagnosed in 2003 and am still going strong!
2.7Patient Review
12/31/2018 After taking Carvedilol for 9 years, I have now been diagnosed with stage 3 kidney disease. I believe it is this medication that has caused this medical problem. My nephologist has cut my pills from two per day to 1/2 twice a day. I want off of Carvedilol as it has ruined my life.
2.3Patient Review
8/15/2016 I have only taken carvedilol for 3 days and I have my head and chest pound when I get up or it is near time for the next dose. I have had a non-stop headache, nausea and a metallic taste in my mouth. I will give it til Friday for improvement. If none I will talk to my doctor about changing.
2Patient Review
2/5/2017 I experienced fatigue, dizziness and headaches. I also started to notice tenderness in my gums and nasal passages.
1.7Patient Review
2/29/2016 Just a week in and I am already feeling the adverse effects of this medication. I'm exhausted, my mouth is blistered and swollen, and my head hurts. My pupils are so dilated that it's hard to see. I also have no control over my bladder and I'm sore all over. This has been miserable.
1.7Patient Review
12/7/2018 I experienced intense exhaustion, swelling of legs, and extreme difficulty breathing while on this medication. I also lost sleep due to my breathing difficulties, which led to body pain and depression. My thinking was also very unclear, and I felt anxious all the time. This drug was a nightmare for me.
1.7Patient Review
2/27/2017 I'm always tired and unable to focus while on this medication, which is not worth the benefit in my opinion.
1Patient Review
2/18/2017 This drug is terrible. My mother was sent home from the hospital with it, and after the first dose she developed shortness of breath and a violent cough. It was so bad that she couldn't breathe, and I thought we were going to lose her.
1Patient Review
7/9/2017 I felt really exhausted after taking this, to the point where it was hard to focus or think clearly. I also had a lot of trouble sleeping, and my knee joints started hurting pretty badly.
1Patient Review
11/6/2020 After only taking this medication for three days, my blood pressure spiked to an incredibly dangerous level. I had to go to the ER and get a bunch of tests done. The only conclusion was that I shouldn't take this drug again, and I definitely won't be.
Patient Q&A Section about coreg
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Coreg a good blood pressure medication?
"Carvedilol, sold under the brand name Coreg among others, is a medication used for treating high blood pressure, heart failure, and left ventricular dysfunction."
Answered by AI
What is the drug Coreg used for?
"Carvedilol is used to treat high blood pressure and heart failure. It can also be used after a heart attack to improve the chances of survival if your heart isn't pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems."
Answered by AI
What are the most common side effects of carvedilol?
"If you experience any of the following symptoms, you may be allergic to the medication: chest pain, discomfort, tightness, or heaviness; dizziness, lightheadedness, or fainting; generalized swelling or swelling of the feet, ankles, or lower legs; pain; shortness of breath; slow heartbeat; weight gain."
Answered by AI
What are the side effects of taking Coreg?
"Coreg may have a number of serious side effects, including low blood pressure, chest pain, an irregular heartbeat, difficulty breathing and swallowing, hives or a rash, swelling, and fainting. People with liver problems should not take Coreg."
Answered by AI