Coreg

Atrial Fibrillation, Ventricular Dysfunction, Left, Heart failure + 5 more
Treatment
9 FDA approvals
20 Active Studies for Coreg

What is Coreg

CarvedilolThe Generic name of this drug
Treatment SummaryCarvedilol is a combination drug used to treat heart failure, left ventricular dysfunction, and high blood pressure. It works by blocking the action of two types of hormones: beta and alpha-1. Carvedilol has been found to be effective in treating moderate cases of hypertension with fewer side effects than higher doses of single drugs. It was approved by the FDA in 1995.
Coregis the brand name
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Coreg Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Coreg
Carvedilol
1997
522

Approved as Treatment by the FDA

Carvedilol, commonly known as Coreg, is approved by the FDA for 9 uses such as Heart failure and Ventricular Dysfunction, Left .
Heart failure
Helps manage NYHA Class I or II heart failure
Ventricular Dysfunction, Left
Helps manage LVEF ≤40% Left ventricular dysfunction
chronic heart failure with reduced ejection fraction (NYHA Class IV)
Helps manage chronic heart failure with reduced ejection fraction (NYHA Class IV)
NYHA Class I or II heart failure
Helps manage NYHA Class I or II heart failure
Hypesthesia
Helps manage chronic heart failure with reduced ejection fraction (NYHA Class III)
LVEF ≤40% Left ventricular dysfunction
Helps manage LVEF ≤40% Left ventricular dysfunction
Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Hypesthesia
Helps manage chronic heart failure with reduced ejection fraction (NYHA Class IV)
Heart Attack
Helps manage Myocardial Infarction

Effectiveness

How Coreg Affects PatientsCarvedilol is a drug used to reduce a rapid heart rate and lower blood pressure. It needs to be taken once a day and is usually given in doses of 10-80mg. It's important to not stop taking carvedilol suddenly, as this can worsen coronary artery disease.
How Coreg works in the bodyCarvedilol reduces heart rate and blood pressure by blocking signals sent to the heart and blood vessels by the sympathetic nervous system. It also has antioxidant properties, which can help prevent cholesterol from building up in the heart.

When to interrupt dosage

The prescribed dosage of Coreg is contingent upon the diagnosed state, including Chronic Stable Angina Pectoris, Ventricular Dysfunction, Left and Hypesthesia. The amount of dosage varies, based on the administration method denoted in the table below.
Condition
Dosage
Administration
Atrial Fibrillation
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Ventricular Dysfunction, Left
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Heart failure
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypesthesia
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Heart Attack
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Hypertensive disease
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral
Angina, Stable
, 10.0 mg, 20.0 mg, 40.0 mg, 80.0 mg, 3.125 mg, 6.25 mg, 12.5 mg, 25.0 mg, 0.125 mg, 50.0 mg
, Oral, Capsule, extended release, Capsule, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Kit, Tablet, coated, Tablet, coated - Oral

Warnings

Coreg has nine contra-indications and its utilization should be avoided in combination with the situations specified in the table below.Coreg Contraindications
Condition
Risk Level
Notes
Bronchospasm
Do Not Combine
Asthma
Do Not Combine
Sick Sinus Syndrome
Do Not Combine
Severe Hepatic Impairment
Do Not Combine
Therapeutic procedure
Do Not Combine
Therapeutic procedure
Do Not Combine
severe bradycardia
Do Not Combine
Atrioventricular Block
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Carvedilol may interact with Pulse Frequency
There are 20 known major drug interactions with Coreg.
Common Coreg Drug Interactions
Drug Name
Risk Level
Description
4-Bromo-2,5-dimethoxyphenethylamine
Major
The therapeutic efficacy of 4-Bromo-2,5-dimethoxyphenethylamine can be decreased when used in combination with Carvedilol.
4-Methoxyamphetamine
Major
The therapeutic efficacy of 4-Methoxyamphetamine can be decreased when used in combination with Carvedilol.
Abediterol
Major
The therapeutic efficacy of Abediterol can be decreased when used in combination with Carvedilol.
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Carvedilol.
Acepromazine
Major
Carvedilol may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Coreg Toxicity & Overdose RiskThose who overdose on the drug may have low blood pressure, slow heartbeats, heart problems, and even cardiac arrest. The patient should be placed in a lying position and can be given atropine for slow heartbeats and glucagon with sympathomimetics to support the cardiovascular system.
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Coreg Novel Uses: Which Conditions Have a Clinical Trial Featuring Coreg?

253 active clinical trials are being conducted to assess the potential of Coreg in providing relief for Hypesthesia, Heart failure and Hypesthesia.
Condition
Clinical Trials
Trial Phases
Atrial Fibrillation
96 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3, Early Phase 1
Hypertensive disease
23 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Heart Attack
26 Actively Recruiting
Not Applicable, Phase 4, Phase 1, Phase 2, Early Phase 1, Phase 3
Angina, Stable
1 Actively Recruiting
Not Applicable
Hypesthesia
10 Actively Recruiting
Not Applicable, Phase 1
Heart failure
0 Actively Recruiting
Hypesthesia
7 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1
Ventricular Dysfunction, Left
0 Actively Recruiting

Coreg Reviews: What are patients saying about Coreg?

5Patient Review
3/25/2018
Coreg for High Blood Pressure
I began taking Coreg at age 58-59. I was prescribed 12.5 mg twice a day, but experienced some side effects in the form of tiredness. This problem was resolved by taking a 20 mg time-released prescription. It's important to note that I only use brand name Coreg; thegeneric version may not be as effective. I also take lisinipril (generic) and an old generic water pill for my blood pressure. The water pill is a big problem because it makes me have to drink more water and avoid salt, but it does bring my blood pressure down well.
5Patient Review
12/17/2019
Coreg for Chronic Heart Failure
I've been on this treatment for two decades and it's really kept me alive and well. I would highly recommend it to others in a similar situation as me.
5Patient Review
7/25/2019
Coreg for Chronic Heart Failure
Coreg has been a lifesaver for me since I was diagnosed with heart failure post chemotherapy. My dose is low, at 6.25 mg twice a day, but it keeps my blood pressure in check and has helped me manage my symptoms effectively.
5Patient Review
12/17/2019
Coreg for Chronic Heart Failure
I've been taking this medication for 20 years now and it's really kept me going. I don't know how I would have fared without it, but I'm grateful that it hasn't caused any organ damage.
5Patient Review
10/14/2017
Coreg for High Blood Pressure
I had no issues with this treatment. My blood pressure is now more stable than ever.
View All Reviews
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Patient Q&A Section about coreg

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Coreg a good blood pressure medication?

"Carvedilol, sold under the brand name Coreg among others, is a medication used for treating high blood pressure, heart failure, and left ventricular dysfunction."

Answered by AI

What is the drug Coreg used for?

"Carvedilol is used to treat high blood pressure and heart failure. It can also be used after a heart attack to improve the chances of survival if your heart isn't pumping well. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems."

Answered by AI

What are the most common side effects of carvedilol?

"If you experience any of the following symptoms, you may be allergic to the medication: chest pain, discomfort, tightness, or heaviness; dizziness, lightheadedness, or fainting; generalized swelling or swelling of the feet, ankles, or lower legs; pain; shortness of breath; slow heartbeat; weight gain."

Answered by AI

What are the side effects of taking Coreg?

"Coreg may have a number of serious side effects, including low blood pressure, chest pain, an irregular heartbeat, difficulty breathing and swallowing, hives or a rash, swelling, and fainting. People with liver problems should not take Coreg."

Answered by AI

Clinical Trials for Coreg

Have you considered Coreg clinical trials? We made a collection of clinical trials featuring Coreg, we think they might fit your search criteria.
Have you considered Coreg clinical trials? We made a collection of clinical trials featuring Coreg, we think they might fit your search criteria.
Have you considered Coreg clinical trials? We made a collection of clinical trials featuring Coreg, we think they might fit your search criteria.
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