Your session is about to expire
What is Dynacirc Cr
IsradipineThe Generic name of this drug
Treatment SummaryIsradipine is a type of drug called a calcium channel blocker (CCB). It works by blocking the movement of calcium into cells in the heart and arteries, lowering blood pressure. Isradipine is the most powerful CCB in its class and is used to treat mild to moderate high blood pressure. It binds to calcium channels with high precision and is more selective for arterial smooth muscle cells than other CCBs.
DynaCircis the brand name
Dynacirc Cr Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
DynaCirc
Isradipine
1998
24
Approved as Treatment by the FDA
Isradipine, also known as DynaCirc, is approved by the FDA for 1 uses including Hypertensive disease .Hypertensive disease
Helps manage High Blood Pressure (Hypertension)
Effectiveness
How Dynacirc Cr Affects PatientsIsradipine helps lower blood pressure by blocking calcium from entering cells. Normally, calcium enters cells and binds to calmodulin, which then starts a process that causes the cells to contract. By preventing calcium from entering the cells, isradipine stops the contraction process and causes the vessels to relax, leading to an overall decrease in blood pressure.
How Dynacirc Cr works in the bodyIsradipine belongs to a class of drugs called calcium channel blockers, which are used to treat high blood pressure. It specifically targets L-type calcium channels, which are present in muscle cells and help to control contraction. Isradipine works by binding to inactive calcium channels and keeping them from activating, which can reduce the contraction of artery walls. It has extra effects on arteries compared to other calcium channel blockers, and is unlikely to affect the heart or the conduction system at therapeutic doses.
When to interrupt dosage
The endorsed dose of Dynacirc Cr is contingent upon the indicated condition. The quantity of dosage is subject to the method of delivery set forth in the below table.Condition
Dosage
Administration
Hypertensive disease
, 2.5 mg, 5.0 mg, 10.0 mg
, Oral, Capsule, Capsule - Oral, Tablet - Oral, Tablet, Tablet, extended release - Oral, Tablet, extended release, Tablet, film coated, extended release - Oral, Tablet, film coated, extended release
Warnings
There are 20 known major drug interactions with Dynacirc Cr.Common Dynacirc Cr Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be decreased when combined with Isradipine.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be decreased when combined with Isradipine.
Alectinib
Major
The metabolism of Alectinib can be decreased when combined with Isradipine.
Alpelisib
Major
The metabolism of Alpelisib can be decreased when combined with Isradipine.
Amifostine
Major
Isradipine may increase the hypotensive activities of Amifostine.
Dynacirc Cr Toxicity & Overdose RiskOverdosing on isradipine can cause tiredness, an abnormally fast heartbeat, and low blood pressure. Mice and rabbits have been found to be more sensitive to the overdose, with doses of over 200mg/kg and 50mg/kg, respectively, resulting in death. Rats, however, were able to tolerate doses of up to 2000mg/kg without any negative effects on survival.
Dynacirc Cr Novel Uses: Which Conditions Have a Clinical Trial Featuring Dynacirc Cr?
18 active trials are in progress to evaluate the potential of Dynacirc Cr in providing relief for Hypertensive disease.Condition
Clinical Trials
Trial Phases
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Dynacirc Cr Reviews: What are patients saying about Dynacirc Cr?
5Patient Review
8/4/2012 This has been the only hypertension medication that I've found to be effective with no side effects. So of course, it gets discontinued and now I'm stuck trying other meds that don't work nearly as well.
5Patient Review
9/11/2009 I have had difficulty breathing on this drug, and tried to tell the doctor it wasn't doing its job. The more I struggle to breathe, the higher my blood pressure goes.
5Patient Review
4/9/2010 The cost is unfortunately quite high, but it's worth it to me to avoid the health risks associated with not taking this medication.
4Patient Review
9/30/2008 This medicine was great for maintaining my blood pressure, but I did have some side effects like swollen ankles and feet. Unfortunately, I can't get a refill right now because the manufacturer is on hold, but my doctor has given me a replacement medication.
4Patient Review
3/2/2008 Unfortunately, this caused swelling in my ankles and feet. I'm going to have to discontinue use and try something else.
4Patient Review
8/2/2011 I find that I have to plan my trips around when I'll be taking this medication, as it causes me to need to urinate frequently and spontaneously about six to eight hours after consumption.
3.7Patient Review
1/15/2008 For the duration of the treatment, I felt flushed and hot. If I moved around too much, I'd feel dizzy and nauseous. Unfortunately, even after a month of taking it, my blood pressure was still high. So all in all, I didn't feel great and saw no results.
3.7Patient Review
9/4/2012 I take this medicine at night before bed with food. it does wake me up to go to the bathroom. thats when I feel the side effects, lightheaded, headache..tried others and couldnt take them..mfg has discontinued. so i buy it online at a much cheaper price. other meds made me very sick. so i will stay with this as long as i can.
3.7Patient Review
9/25/2008 I had to switch because the manufacturer isn't currently selling this drug.
3.7Patient Review
2/17/2010 No complaints here! This treatment was great.
3.3Patient Review
8/27/2008 I ended up in the hospital due to low sodium levels after taking this medication. I had a whole host of other symptoms, including nausea, vomiting, diarrhea, headache, and sinus problems.
3Patient Review
11/27/2007 I experienced abdominal pain, headaches, aching joints, and bloating while taking this medication. I was also taking labetolol at the time, so I'm not sure if it was the combination of the two that caused these side effects.
2.7Patient Review
7/15/2008 The constant migraines I experienced while on this medication were really scary. The side effects never went away, so I stopped taking it.
2.7Patient Review
10/20/20072.3Patient Review
6/21/2008 While this did help lower my blood pressure, the side effects of headaches and dizziness were really tough to deal with.
1.7Patient Review
8/17/2009 I was really disappointed when I learned that this drug is no longer available. I've had success with it in the past, and I'm struggling to find a replacement that works as well. If anyone knows why this drug is no longer available, please let me know.
1Patient Review
8/14/2008 This drug caused swelling, muscle pains and cramps. It's also been very difficult to refill my prescription since May '08. I'm getting off of this medication as soon as possible and selling the pharmaceutical stock too.
Patient Q&A Section about dynacirc cr
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is DynaCirc CR still available?
"This product is no longer being manufactured under the DynaCirc CR brand name. If the FDA has approved generic versions of this product, there may be cheaper equivalents available from other manufacturers."
Answered by AI
What is DynaCirc used for?
"Its a medication that works by blocking calcium channels in order to lower blood pressure. It can be used in tandem with a diuretic in order to maximize its effects."
Answered by AI
What class of drug is isradipine?
"Isradipine is a type of medication referred to as a calcium channel blocker. Its purpose is to relax blood vessels so that the heart doesn't have to work as hard."
Answered by AI
How long does it take for isradipine to work?
"You will not see the full benefits of this drug for 2 to 4 weeks. If you do not notice an improvement or if your blood pressure readings increase, tell your doctor."
Answered by AI