← Back to Search

Family Health History Assessment for Cancer Risk (FOREST Trial)

N/A

Waitlist Available

Led By Georgia Wiesner, MD

Research Sponsored by Vanderbilt University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 years

Awards & highlights

FOREST Trial Summary

This trial is studying a family health history questionnaire called MeTree to see how well it works in determining a person's risk for cancer.

Who is the study for?

This study is for English-speaking individuals who are comfortable using the internet and are patients at specific sites included in the study. They must be willing to enroll or already be enrolled in a patient portal (specifically for VUMC). People with terminal illnesses, previous genetic counseling or testing from VUMC's Hereditary Cancer Clinic, or those not receiving care at study sites cannot participate.Check my eligibility

What is being tested?

The trial is examining how well MeTree, a family health history platform, can assess cancer risk based on guidelines. Participants will fill out surveys and the MeTree questionnaire. High-risk participants will receive genetic counseling. The effectiveness of MeTree will be compared to traditional pedigree assessments.See study design

What are the potential side effects?

Since this trial involves completing questionnaires and does not include medication or invasive procedures, there are no direct physical side effects expected. However, learning about personal cancer risks may cause emotional or psychological stress.

FOREST Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Use of MeTree Questionnaire

Secondary outcome measures

High-risk invitation to HCC

FOREST Trial Design

1Treatment groups

Experimental Treatment

Group I: High Risk / MeTreeExperimental Treatment1 Intervention

High risk for hereditary cancer and completes the MeTree questionnaire

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH

13,654 Previous Clinical Trials

40,931,482 Total Patients Enrolled

Vanderbilt University Medical CenterLead Sponsor

856 Previous Clinical Trials

670,521 Total Patients Enrolled

Georgia Wiesner, MDPrincipal InvestigatorVanderbilt University Medical Center

Media Library

High Risk / MeTree Clinical Trial Eligibility Overview. Trial Name: NCT05079334 — N/A

Cancer Research Study Groups: High Risk / MeTree

Cancer Clinical Trial 2023: High Risk / MeTree Highlights & Side Effects. Trial Name: NCT05079334 — N/A

High Risk / MeTree 2023 Treatment Timeline for Medical Study. Trial Name: NCT05079334 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the estimated size of the cohort engaged in this research?

"Yes, according to clinicaltrials.gov, this medical trial is actively seeking participants and was recently updated on the 26th September 2022; it began recruiting patients from January 1st of this year. Approximately 3500 people are being recruited across two centres."

Answered by AI

Is the application window for this study still open to potential participants?

"Affirmative. According to the clinicaltrials.gov database, this research project is actively enrolling individuals. Originally posted on January 1st 2022 and last modified on September 26th of the same year, 3500 participants need to be recruited from 2 sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Family History and Cancer Risk Study

Georgia Wiesner 2022. "Family History and Cancer Risk Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05079334.