Moexipril Hydrochloride

Hypertensive disease
Treatment
1 FDA approval
20 Active Studies for Moexipril Hydrochloride

What is Moexipril Hydrochloride

MoexiprilThe Generic name of this drug
Treatment SummaryHydrochlorothiazide is a type of medication used to treat edema, or swelling, and high blood pressure. It is the most commonly prescribed thiazide diuretic, but is being used less often in favor of other medications such as angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. This drug has been approved by the FDA since 1959 and is often combined with other medications for more effective treatment.
Univascis the brand name
image of different drug pills on a surface
Moexipril Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Univasc
Moexipril
1995
42

Approved as Treatment by the FDA

Moexipril, commonly known as Univasc, is approved by the FDA for 1 uses like Hypertensive disease .
Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide

Effectiveness

How Moexipril Hydrochloride Affects PatientsHydrochlorothiazide helps the body get rid of extra water by preventing the kidneys from reabsorbing water from the urine. The amount taken will vary from person to person, usually ranging from 25-100mg. People with reduced kidney or liver function should be careful when taking this drug.
How Moexipril Hydrochloride works in the bodyHydrochlorothiazide helps your body remove sodium and water. It is transported from the bloodstream into cells in your kidneys. Sodium is normally absorbed by these cells and pumped into the area around them, creating an imbalance that helps the body absorb more water. Hydrochlorothiazide acts on this area of the kidneys and prevents sodium from being absorbed, so the body absorbs less water.

When to interrupt dosage

The prescribed amount of Moexipril Hydrochloride is contingent upon the diagnosed condition, including Antepartum magnesium sulfate prophylaxis, inadequately regulated blood pressure with monotherapy and antihypertensives. The dose of dosage is contingent upon the approach of administration (e.g. Tablet, coated - Oral or Oral) provided in the table below.
Condition
Dosage
Administration
Hypertensive disease
, 7.5 mg, 15.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet - Oral, Tablet, Tablet, coated - Oral, Tablet, coated

Warnings

Moexipril Hydrochloride has two contraindications and should not be blended with any of the conditions outlined in the below table.Moexipril Hydrochloride Contraindications
Condition
Risk Level
Notes
Angioedema
Do Not Combine
Type 2 Diabetes
Do Not Combine
Pulse Frequency
Do Not Combine
Anuria
Do Not Combine
There are 20 known major drug interactions with Moexipril Hydrochloride.
Common Moexipril Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Moexipril may increase the hypotensive activities of Amifostine.
Azathioprine
Major
The risk or severity of myelosuppression, anemia, and severe leukopenia can be increased when Moexipril is combined with Azathioprine.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Moexipril is combined with Hydroxyzine.
Lithium carbonate
Major
The serum concentration of Lithium carbonate can be increased when it is combined with Moexipril.
Lithium citrate
Major
The serum concentration of Lithium citrate can be increased when it is combined with Moexipril.
Moexipril Hydrochloride Toxicity & Overdose RiskThe toxic dose of hydrochlorothiazide in mice and rats is greater than 10g/kg. Symptoms of overdose may include low levels of potassium, chlorine, or sodium in the blood. Treatment for overdose will involve providing fluids and electrolytes, and oxygen may be given if breathing is affected. To treat low blood pressure, the patient may receive vasopressors.
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Moexipril Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Moexipril Hydrochloride?

158 active clinical trials are assessing the potential of Moexipril Hydrochloride to ameliorate Cirrhosis, Edema, and Congestive Heart Failure.
Condition
Clinical Trials
Trial Phases
Hypertensive disease
27 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3

Moexipril Hydrochloride Reviews: What are patients saying about Moexipril Hydrochloride?

5Patient Review
7/2/2008
Moexipril Hydrochloride for High Blood Pressure
I've been taking this for years with no issues, but about four months ago my blood pressure started going up again. I'm still on the medication, plus atenolol. So far it's not been too bad.
5Patient Review
1/20/2013
Moexipril Hydrochloride for High Blood Pressure
I had no problems with this medication, but my doctor wants to remove the diuretic. The pharmacy claims that no one cares about that medicine anymore. Are there any possible substitutes?
3.7Patient Review
2/16/2010
Moexipril Hydrochloride for High Blood Pressure
My blood pressure has been higher in the evening since taking this drug, which is not ideal.
3Patient Review
3/16/2010
Moexipril Hydrochloride for Osteoporosis
This treatment is okay. I'm not a huge fan of drugs, but this one helped me.
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Patient Q&A Section about moexipril hydrochloride

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

When should moexipril be taken?

"Moexipril is a drug typically taken once or twice daily, on an empty stomach and either one hour before or two hours after a meal. It is recommended that users take the drug at the same time(s) each day in order to help with remembering to take the medication."

Answered by AI

What is the brand name for moexipril?

"Univasc is a Brand name for the drug Ranolazine and is manufactured by Par Pharmaceutical.

The brand name for the drug Ranolazine is Univasc, and it is manufactured by Par Pharmaceutical."

Answered by AI

Why was moexipril discontinued?

"Product number 2691 has been discontinued and is no longer for sale."

Answered by AI

What is moexipril used for?

"Moexipril is used to treat high blood pressure. High blood pressure can strain the heart and arteries, and if left untreated, can cause long-term damage to the heart and arteries."

Answered by AI

Clinical Trials for Moexipril Hydrochloride

Image of U Health in Miami, United States.

Cuffless PPG Monitor for High Blood Pressure

18+
All Sexes
Miami, FL
This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM) method using an upper arm cuff-based oscillometric BP device, in both hypertensive and normotensive individuals referred by their provider to undergo a 24-hours ABPM for clinical indication. The Awake/Asleep test, which is the primary test recommended for automated wearable cuffless BP devices that are cuff-calibrated (based on the 2023 European Society of Hypertension (ESH) recommendations for the validation of cuffless blood pressure measuring devices), will be conducted in this study. The secondary aim of the study is to assess the feasibility and convenience of the PPG-based device.
Waitlist Available
Has No Placebo
U Health (+1 Sites)Ziad Zoghby, M.D., M.B.A.Biobeat Technologies Ltd.
Have you considered Moexipril Hydrochloride clinical trials? We made a collection of clinical trials featuring Moexipril Hydrochloride, we think they might fit your search criteria.Go to Trials
Have you considered Moexipril Hydrochloride clinical trials? We made a collection of clinical trials featuring Moexipril Hydrochloride, we think they might fit your search criteria.Go to Trials
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Egg White Powder for High Blood Sugar and High Blood Pressure

18 - 70
All Sexes
Edmonton, Canada
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides. This is a feasibility study to assess the acute effect of IRW in egg white hydrolysate for the management of high sugar and blood pressure. Participants at high risk of type 2 diabetes (T2D) or having T2D will undergo 4 consecutive treatments of 1 day each (randomly), during which they will consume a standardized breakfast with a smoothie containing different protein powders. Each treatment will be separated by a minimum of 1-week. Participants in the healthy control group will undergo 1 treatment only (one day).
Phase 1
Waitlist Available
University of AlbertaJianping Wu, PhD
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CardioCare Quest for High Blood Pressure

18+
All Sexes
Flagstaff, AZ
This project aims to address healthcare disparities among Navaho people diagnosed with hypertension or prehypertension through three main objectives. Firstly, it identifies and shares insights on healthcare access disparities affecting Navaho individuals experiencing nonadherence to hypertension treatment. Secondly, the proposal develops a telehealth solution based on factors identified as knowledge gaps caused by healthcare access disparities in hypertension management; we will use the factors to design a series of engaging minigames that can be incorporated into the larger CardioCare Quest. These minigames will be co-designed with end users and clinicians. Finally, the proposal conducts comprehensive qualitative and quantitative assessments of user experiences, perceptions, and challenges with CardioCare Quest.
Recruiting
Has No Placebo
Northern Arizona University (+1 Sites)Tochukwu Ikwunne, PhD
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Food as Medicine for Cardiometabolic Health

18+
All Sexes
Boston, MA
Though the Mississippi Delta has a rich agricultural history and some of the nation's most fertile soil, residents have experienced the legacy of slavery and economic exploitation through food insecurity and poverty for generations. This project focuses on Bolivar, Washington, and Sunflower, contiguous counties in the Delta that are designated as health disparity populations. Over 65% of the 100,000 residents are Black/African American and \~30% live at or below the poverty level. Obesity rates are high and the rate of diabetes is almost double the national average. Tufts University received a grant from the National Institute of Minority Health and Health Disparities to develop, test, and evaluate a Food is Medicine program in Mississippi. The Delta Growing a Resilient, Enriching, Equitable, Nourishing food System (GREENS) Food is Medicine (FIM) Project, is a collaborative project in Bolivar, Washington, and Sunflower counties in Mississippi. The intervention involves regularly distributed fruit and vegetable produce boxes as well as nutrition education materials to the intervention group. The control group will receive produce boxes later, after they complete study activities. The project's primary goal is to improve health outcomes by creating a FIM intervention. The Delta GREENS FIM Project aims to become a model for promoting nutrition security and management of chronic conditions in varied communities nationwide.
Recruiting
Has No Placebo
Tufts UniversityChristina D Economos, PhD
Have you considered Moexipril Hydrochloride clinical trials? We made a collection of clinical trials featuring Moexipril Hydrochloride, we think they might fit your search criteria.Go to Trials
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