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What is Moexipril Hydrochloride
MoexiprilThe Generic name of this drug
Treatment SummaryHydrochlorothiazide is a type of medication used to treat edema, or swelling, and high blood pressure. It is the most commonly prescribed thiazide diuretic, but is being used less often in favor of other medications such as angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. This drug has been approved by the FDA since 1959 and is often combined with other medications for more effective treatment.
Univascis the brand name
Moexipril Hydrochloride Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Univasc
Moexipril
1995
42
Approved as Treatment by the FDA
Moexipril, commonly known as Univasc, is approved by the FDA for 1 uses like Hypertensive disease .Hypertensive disease
Used to treat High Blood Pressure (Hypertension) in combination with Hydrochlorothiazide
Effectiveness
How Moexipril Hydrochloride Affects PatientsHydrochlorothiazide helps the body get rid of extra water by preventing the kidneys from reabsorbing water from the urine. The amount taken will vary from person to person, usually ranging from 25-100mg. People with reduced kidney or liver function should be careful when taking this drug.
How Moexipril Hydrochloride works in the bodyHydrochlorothiazide helps your body remove sodium and water. It is transported from the bloodstream into cells in your kidneys. Sodium is normally absorbed by these cells and pumped into the area around them, creating an imbalance that helps the body absorb more water. Hydrochlorothiazide acts on this area of the kidneys and prevents sodium from being absorbed, so the body absorbs less water.
When to interrupt dosage
The prescribed amount of Moexipril Hydrochloride is contingent upon the diagnosed condition, including Antepartum magnesium sulfate prophylaxis, inadequately regulated blood pressure with monotherapy and antihypertensives. The dose of dosage is contingent upon the approach of administration (e.g. Tablet, coated - Oral or Oral) provided in the table below.Condition
Dosage
Administration
Hypertensive disease
, 7.5 mg, 15.0 mg
, Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, coated - Oral, Tablet, coated
Warnings
Moexipril Hydrochloride has two contraindications and should not be blended with any of the conditions outlined in the below table.Moexipril Hydrochloride ContraindicationsCondition
Risk Level
Notes
Angioedema
Do Not Combine
Type 2 Diabetes
Do Not Combine
Pulse Frequency
Do Not Combine
Anuria
Do Not Combine
Common Moexipril Hydrochloride Drug Interactions
Drug Name
Risk Level
Description
Amifostine
Major
Moexipril may increase the hypotensive activities of Amifostine.
Azathioprine
Major
The risk or severity of myelosuppression, anemia, and severe leukopenia can be increased when Moexipril is combined with Azathioprine.
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Moexipril is combined with Hydroxyzine.
Lithium carbonate
Major
The serum concentration of Lithium carbonate can be increased when it is combined with Moexipril.
Lithium citrate
Major
The serum concentration of Lithium citrate can be increased when it is combined with Moexipril.
Moexipril Hydrochloride Toxicity & Overdose RiskThe toxic dose of hydrochlorothiazide in mice and rats is greater than 10g/kg. Symptoms of overdose may include low levels of potassium, chlorine, or sodium in the blood. Treatment for overdose will involve providing fluids and electrolytes, and oxygen may be given if breathing is affected. To treat low blood pressure, the patient may receive vasopressors.
Moexipril Hydrochloride Novel Uses: Which Conditions Have a Clinical Trial Featuring Moexipril Hydrochloride?
158 active clinical trials are assessing the potential of Moexipril Hydrochloride to ameliorate Cirrhosis, Edema, and Congestive Heart Failure.Condition
Clinical Trials
Trial Phases
Hypertensive disease
19 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 3
Moexipril Hydrochloride Reviews: What are patients saying about Moexipril Hydrochloride?
5Patient Review
7/2/2008 I've been taking this for years with no issues, but about four months ago my blood pressure started going up again. I'm still on the medication, plus atenolol. So far it's not been too bad.
5Patient Review
1/20/2013 I had no problems with this medication, but my doctor wants to remove the diuretic. The pharmacy claims that no one cares about that medicine anymore. Are there any possible substitutes?
3.7Patient Review
2/16/2010 My blood pressure has been higher in the evening since taking this drug, which is not ideal.
3Patient Review
3/16/2010 This treatment is okay. I'm not a huge fan of drugs, but this one helped me.
Patient Q&A Section about moexipril hydrochloride
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.When should moexipril be taken?
"Moexipril is a drug typically taken once or twice daily, on an empty stomach and either one hour before or two hours after a meal. It is recommended that users take the drug at the same time(s) each day in order to help with remembering to take the medication."
Answered by AI
What is the brand name for moexipril?
"Univasc is a Brand name for the drug Ranolazine and is manufactured by Par Pharmaceutical.
The brand name for the drug Ranolazine is Univasc, and it is manufactured by Par Pharmaceutical."
Answered by AI
Why was moexipril discontinued?
"Product number 2691 has been discontinued and is no longer for sale."
Answered by AI
What is moexipril used for?
"Moexipril is used to treat high blood pressure. High blood pressure can strain the heart and arteries, and if left untreated, can cause long-term damage to the heart and arteries."
Answered by AI