Galzin

Itching, Exanthema, Exanthema + 7 more

Treatment

3 FDA approvals

4 Active Studies for Galzin

What is Galzin

Zinc acetate

The Generic name of this drug

Tecnu Calagel

is the brand name

image of different drug pills on a surface

Galzin Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Tecnu Calagel

Zinc acetate

1992

2

Approved as Treatment by the FDA

Zinc acetate, otherwise called Tecnu Calagel, is approved by the FDA for 3 uses which include Pruritus and Skin Irritation .

Pruritus

Skin Irritation

Itching

Effectiveness

How Galzin Affects Patients

Zinc is an important mineral for many bodily functions. It helps with the activity of enzymes, immune system, wound healing, protein and DNA production, and cell division. It is also essential for a healthy sense of taste and smell, and is important for growth and development. Some studies suggest that zinc can act as an antioxidant, protecting the body from aging, and can help speed up the healing process. Zinc taken in low amounts has been found to be an effective antimicrobial agent. Taking zinc supplements in the form of lozenges or syrup within 24 hours of cold symptoms may shorten the length of a cold. People with skin ul

How Galzin works in the body

Zinc has three main roles: catalytic, structural, and regulatory. It helps build proteins that are responsible for cell signaling, and it works as a protective antioxidant. Zinc also helps to regulate the body's immune response. It can increase production of antibodies and reduce inflammation. Zinc deficiency can lead to decreased activity of T-helper cells, which are responsible for killing bacteria and viruses. Studies have also shown that zinc can help reduce levels of acne-causing bacteria, as well as reduce inflammation associated with acne. The exact mechanism of action is not well understood.

When to interrupt dosage

The advised dose of Galzin is contingent upon the diagnosed affliction, for example Exanthema, Pain and Exanthema. The amount of dosing depends on the delivery approach outlined in the table beneath.

Condition

Dosage

Administration

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Optic Atrophy, Autosomal Dominant

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Itching

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Pain

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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Skin Irritation

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

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oozing and weeping

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Liquid, Powder, for suspension - Topical, Powder, for suspension, Liquid - Topical, Cream, Aerosol, Solution, Solution - Topical, Capsule - Oral, Oral, Capsule, Soap, Gel - Topical, Aerosol, spray - Topical, Ointment - Topical, Aerosol, spray, Ointment, Aerosol - Topical, Auricular (otic), Solution - Auricular (otic), Gel, Soap - Topical, Kit, Kit - Oral; Topical, Oral; Topical, Lozenge, Lozenge - Oral

Exanthema

, 1.0 mg/mL, 0.0001 mg/mg, 0.001 mg/mg, 0.001 mL/mL, 1.2 mg/mL, 0.000001 mL/mL, 10.0 mg/mL, 0.0035 mg/mg, 0.001 mg/mL, 7.5 mg/mL, 0.882 mg/mL, 0.015 mg/mg, 0.15 mg/mg, 0.1 mg/mg, 0.0076 mg/mg, 0.000001 units/mg, 0.1 %, 0.1 mg/mL, 50.0 mg, 25.0 mg, 5.31 mg/mL, 0.0025 mg/mg, 0.00215 mg/mg, 2.15 mg/mL, 20.0 mg/mL, 0.0284 mg/mg, 0.012 mg/mg, 882.0 mg/mL, 7.6 mg/mL, 0.02 mL/mL, 0.0075 mg/mg, 100000.0 mg/mL, 0.002 mg/mg, 0.01 mg/mg, 0.015 mg/mL, 5.5 mg

, Lotion - Topical, Topical, Lotion, Spray, Spray - Topical, Cream - Topical, Liquid, Powder, for suspension - Topical, Powder, for suspension, Liquid - Topical, Cream, Aerosol, Solution, Solution - Topical, Capsule - Oral, Oral, Capsule, Soap, Gel - Topical, Aerosol, spray - Topical, Ointment - Topical, Aerosol, spray, Ointment, Aerosol - Topical, Auricular (otic), Solution - Auricular (otic), Gel, Soap - Topical, Kit, Kit - Oral; Topical, Oral; Topical, Lozenge, Lozenge - Oral

Warnings

There are 20 known major drug interactions with Galzin.

Common Galzin Drug Interactions

Drug Name

Risk Level

Description

Deferasirox

Major

Zinc acetate can cause a decrease in the absorption of Deferasirox resulting in a reduced serum concentration and potentially a decrease in efficacy.

Raltegravir

Major

Zinc acetate can cause a decrease in the absorption of Raltegravir resulting in a reduced serum concentration and potentially a decrease in efficacy.

Halofantrine

Minor

Zinc acetate can cause a decrease in the absorption of Halofantrine resulting in a reduced serum concentration and potentially a decrease in efficacy.

Carbamazepine

Moderate

Zinc acetate can cause a decrease in the absorption of Carbamazepine resulting in a reduced serum concentration and potentially a decrease in efficacy.

Ceftibuten

Moderate

Zinc acetate can cause a decrease in the absorption of Ceftibuten resulting in a reduced serum concentration and potentially a decrease in efficacy.

Galzin Toxicity & Overdose Risk

The toxicity of zinc is much lower than that of cadmium and mercury, with an oral LD50 of around 3g/kg body weight. Studies on rats and mice have also found that the LD50 of zinc compounds ranges from 186 to 623 mg zinc/kg/day.

Galzin Novel Uses: Which Conditions Have a Clinical Trial Featuring Galzin?

16 current studies are assessing the efficacy of Galzin in providing relief for Poison oak rash, Itch and Pain.

Condition

Clinical Trials

Trial Phases

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Skin Irritation

0 Actively Recruiting

Pain

0 Actively Recruiting

oozing and weeping

0 Actively Recruiting

Exanthema

0 Actively Recruiting

Itching

3 Actively Recruiting

Phase 3, Not Applicable

Optic Atrophy, Autosomal Dominant

1 Actively Recruiting

Not Applicable

Galzin Reviews: What are patients saying about Galzin?

5

Patient Review

12/3/2008

Galzin for Excessive Copper Deposits in the Liver and Brain

I have IBS and this drug usually helps me if I take it right after meals.

5

Patient Review

9/13/2010

Galzin for Excessive Copper Deposits in the Liver and Brain

With the help of TTM, my copper levels have normalized. I have been through a lot ( massive damage from dystonia), but this treatment has really helped me.

4.7

Patient Review

10/1/2015

Galzin for Excessive Copper Deposits in the Liver and Brain

I have Wilson's Disease and was diagnosed when I was 21. I took Galzin with TTM for six months, then continued taking it by itself. The only cons are that you have to take it on an empty stomach, and the cost. This drug is not affordable, but it seems to be working as intended-- keeping me from liver toxicity. The stomach pain is ignorable since it feels like hunger pangs.

4.3

Patient Review

11/26/2007

Galzin for Excessive Copper Deposits in the Liver and Brain

The only downside to this medication is that it must be taken on an empty stomach. Other than that, it's much better than other similar treatments I've tried.

4

Patient Review

5/6/2008

Galzin for Excessive Copper Deposits in the Liver and Brain

Though I sometimes experience nausea and stomach ache after taking this capsule, it has been effective in treating my illness.

4

Patient Review

2/14/2011

Galzin for Excessive Copper Deposits in the Liver and Brain

I take this medication right after eating and have never had any issues with stomach upset. Additionally, I think the price is fair.

3.7

Patient Review

11/18/2009

Galzin for Excessive Copper Deposits in the Liver and Brain

After six months of treatment, I developed an allergy to the medication. This caused a loss of taste, itching, and numbness in my mouth.

2.3

Patient Review

10/26/2011

Galzin for Excessive Copper Deposits in the Liver and Brain

I've been managing my WD with Galzin for over a decade, and it's always helped keep my tests normal. However, I really disliked taking it on an empty stomach in the morning; it would give me terrible nausea. My doctor suggested that I try Gluzin instead, and so far it seems to be less irritating.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about galzin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can we take zinc acetate empty stomach?

"Follow the dosage guidelines and take on an empty stomach. If zinc acetate upsets your stomach, take the medicine between breakfast and lunch. Swallow the capsule whole and do not attempt to open, chew, break, or crush it."

Answered by AI

What is the use of zinc acetate tablets?

"This medication is used as a last resort to treat Wilson's disease, an inherited disease which causes the liver to hold onto too much copper and results in liver damage and other serious problems."

Answered by AI

What is galzin?

"Galzin is a medication used to prevent blood copper levels from getting too high in people with Wilson disease."

Answered by AI

Is galzin same as zinc?

"The capsules contain either 25 or 50 mg of zinc, in addition to corn starch and magnesium stearate. The 25 mg capsule shells contain titanium dioxide, and the 50 mg capsule shells contain titanium dioxide, methylparaben, and propylparaben."

Answered by AI

Clinical Trials for Galzin

Image of Johns Hopkins Bayview Medical Center in Baltimore, United States.

VR-Enhanced PMR for Post-Burn Symptoms

18+
All Sexes
Baltimore, MD

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to answer are: * Does VR-enhanced PMR (VR-PMR) reduce chronic pain, anxiety, itch, sleep disturbances, and fatigue more effectively than standard PMR? * Is VR-PMR a feasible and acceptable self-administered home-based intervention for burn survivors? Researchers will compare two self-administered intervention conditions, VR-enhanced PMR and standard PMR, using a randomized to sequence crossover design to see if VR technology enhances the therapeutic effects of PMR on chronic symptom management in burn survivors. Participants will: * Complete home-based sessions of VR-enhanced PMR * Complete home-based sessions of standard PMR * Report symptoms such as pain, itch, anxiety, sleep disturbances, and fatigue throughout the study * Use VR equipment provided for the intervention period (during the VR-PMR arm)

Recruiting
Has No Placebo

Johns Hopkins Bayview Medical Center

Sheera Lerman Zohar, PhD