Lipidil

Hypertriglyceridemia, Hypertriglyceridemia, Primary Hypercholesterolemia + 2 more
Treatment
8 FDA approvals
19 Active Studies for Lipidil

What is Lipidil

FenofibrateThe Generic name of this drug
Treatment SummaryFenofibrate is a medication used to reduce cholesterol and triglyceride levels in the blood. It belongs to a group of drugs known as fibric acid derivatives and is similar to clofibrate and gemfibrozil. Fenofibrate is used to treat high cholesterol, mixed dyslipidemia, and extremely high levels of triglycerides in the blood. It was approved by the FDA in 1993.
Tricoris the brand name
image of different drug pills on a surface
Lipidil Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tricor
Fenofibrate
2002
421

Approved as Treatment by the FDA

Fenofibrate, also known as Tricor, is approved by the FDA for 8 uses which include Hypertriglyceridemia and severe Fredrickson Type V Hypertriglyceridemia .
Hypertriglyceridemia
severe Fredrickson Type V Hypertriglyceridemia
Severe Hypertriglyceridemia (sHTG)
Primary Hypercholesterolemia
Hypertriglyceridemia
Hypertriglyceridemia
severe Fredrickson Type IV Hypertriglyceridemia
Dyslipidemias

Effectiveness

How Lipidil Affects PatientsFenofibrate is a medication used to lower cholesterol levels and treat high triglycerides. It needs to be taken once a day and works for up to 27 hours. It is usually taken in doses of 50-150mg. It is important to tell patients about the risks of muscle damage, muscle pain, and gallstones that can occur when taking fibrates.
How Lipidil works in the bodyFenofibrate helps break down fat molecules in the body by activating a receptor called PPAR-alpha. This receptor helps control how much fat and other substances are in the body, and activating it encourages the body to break down more fat molecules. This process also increases the amount of oxidative stress in the liver, which can cause serious health problems like cirrhosis and hepatitis in rare cases.

When to interrupt dosage

The proposed measure of Lipidil is contingent upon the diagnosed condition, for example, severe Fredrickson Type V Hypertriglyceridemia, Dyslipidemias and Hypertriglyceridemia. The dose likewise varies as per the delivery approach (e.g. Oral or Tablet, film coated) recorded in the table beneath.
Condition
Dosage
Administration
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Primary Hypercholesterolemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Dyslipidemias
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

Lipidil has three contraindications and should not be ingested while dealing with any of the circumstances outlined in the subsequent table.Lipidil Contraindications
Condition
Risk Level
Notes
Liver Diseases
Do Not Combine
Gallbladder Diseases
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fenofibrate may interact with Pulse Frequency
There are 20 known major drug interactions with Lipidil.
Common Lipidil Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Fenofibrate.
Aluminium clofibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Aluminium clofibrate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Fenofibrate.
Bezafibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Bezafibrate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Fenofibrate.
Lipidil Toxicity & Overdose RiskThe lowest toxic dose of fenofibrate in rats is greater than 2g/kg and 1600mg/kg in mice. If someone has recently overdosed on fenofibrate, they should be monitored and treated with supportive care, such as inducing vomiting or gastric lavage. Since it binds to proteins, hemodialysis is not likely to be effective.
image of a doctor in a lab doing drug, clinical research

Lipidil Novel Uses: Which Conditions Have a Clinical Trial Featuring Lipidil?

Fifteen active trials are investigating the use of Lipidil to treat severe Fredrickson Type V Hypertriglyceridemia, Hypertriglyceridemia and Dyslipidemias.
Condition
Clinical Trials
Trial Phases
Primary Hypercholesterolemia
10 Actively Recruiting
Phase 3, Phase 2, Not Applicable
Hypertriglyceridemia
8 Actively Recruiting
Phase 3, Phase 2
Hypertriglyceridemia
0 Actively Recruiting
Hypertriglyceridemia
0 Actively Recruiting
Dyslipidemias
1 Actively Recruiting
Phase 2

Lipidil Reviews: What are patients saying about Lipidil?

5Patient Review
9/20/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I was initially prescribed statins, which caused memory problems and extreme muscle weakness. These effects lingered for three years before my doctor switched me to Welchol. While this helped somewhat, it wasn't enough so he added 145mg of finofibrate to the mix. This lowered my cholesterol significantly with no noticeable side effects.
5Patient Review
9/14/2014
Lipidil for High Cholesterol
I've been doing great since having my gallbladder removed. This treatment was definitely worth it.
5Patient Review
1/5/2019
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I experienced none of the negative side effects that others have described. This drug was also much more effective than any other treatment I've tried in the past. I go for blood work every 3 months and haven't seen any signs of this drug affecting my body negatively.
5Patient Review
6/3/2017
Lipidil for High Amount of Triglyceride in the Blood
In addition to a statin drug, this treatment halved my triglyceride levels.
5Patient Review
9/14/2014
Lipidil for High Cholesterol
I had to get my gallbladder removed, but I've been doing great since then.
View All Reviews

Patient Q&A Section about lipidil

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Lipidil have side effects?

"If you experience any of the following side effects, see your doctor as soon as possible:

Signs of liver problems, such as dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin."

Answered by AI

What is the generic name for Lipidil?

"The generic name for fenofibrate is fenofibrate. It is a medication that is used to treat high cholesterol and triglyceride levels in the blood. It is a Prescription Only Medicine (POM) which means it can only be prescribed by a healthcare professional."

Answered by AI

When should Lipidil be taken?

"The recommended dosage of Lipidil 145 mg and 48 mg is to be taken at the same time each day, with or without food."

Answered by AI

What is Lipidil for?

"LIPIDIL is used to help regulate cholesterol and triglycerides in the blood. These are fat-like substances that can build up and cause problems."

Answered by AI

Clinical Trials for Lipidil

Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.
Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.
Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.
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