Lipidil

Hypertriglyceridemia, severe Fredrickson Type V Hypertriglyceridemia, Primary Hypercholesterolemia + 2 more
Treatment
5 FDA approvals
20 Active Studies for Lipidil

What is Lipidil

FenofibrateThe Generic name of this drug
Treatment SummaryFenofibrate is a medication used to reduce cholesterol and triglyceride levels in the blood. It belongs to a group of drugs known as fibric acid derivatives and is similar to clofibrate and gemfibrozil. Fenofibrate is used to treat high cholesterol, mixed dyslipidemia, and extremely high levels of triglycerides in the blood. It was approved by the FDA in 1993.
Tricoris the brand name
image of different drug pills on a surface
Lipidil Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tricor
Fenofibrate
2002
421

Approved as Treatment by the FDA

Fenofibrate, also known as Tricor, is approved by the FDA for 5 uses which include Primary Hypercholesterolemia and Hypertriglyceridemia .
Primary Hypercholesterolemia
Hypertriglyceridemia
Dyslipidemias
Hypertriglyceridemia
severe Fredrickson Type V Hypertriglyceridemia

Effectiveness

How Lipidil Affects PatientsFenofibrate is a medication used to lower cholesterol levels and treat high triglycerides. It needs to be taken once a day and works for up to 27 hours. It is usually taken in doses of 50-150mg. It is important to tell patients about the risks of muscle damage, muscle pain, and gallstones that can occur when taking fibrates.
How Lipidil works in the bodyFenofibrate helps break down fat molecules in the body by activating a receptor called PPAR-alpha. This receptor helps control how much fat and other substances are in the body, and activating it encourages the body to break down more fat molecules. This process also increases the amount of oxidative stress in the liver, which can cause serious health problems like cirrhosis and hepatitis in rare cases.

When to interrupt dosage

The proposed measure of Lipidil is contingent upon the diagnosed condition, for example, severe Fredrickson Type V Hypertriglyceridemia, Dyslipidemias and Hypertriglyceridemia. The dose likewise varies as per the delivery approach (e.g. Oral or Tablet, film coated) recorded in the table beneath.
Condition
Dosage
Administration
Dyslipidemias
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
severe Fredrickson Type V Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Primary Hypercholesterolemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral
Hypertriglyceridemia
145.0 mg, 48.0 mg, , 160.0 mg, 54.0 mg, 43.0 mg, 130.0 mg, 67.0 mg, 200.0 mg, 134.0 mg, 1.45 mg, 1.6 mg, 40.0 mg, 120.0 mg, 150.0 mg, 50.0 mg, 100.0 mg, 30.0 mg, 90.0 mg, 87.0 mg
Oral, Tablet, , Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral

Warnings

Lipidil has three contraindications and should not be ingested while dealing with any of the circumstances outlined in the subsequent table.Lipidil Contraindications
Condition
Risk Level
Notes
active liver disease
Do Not Combine
Gall Bladder Diseases
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Fenofibrate may interact with Pulse Frequency
There are 20 known major drug interactions with Lipidil.
Common Lipidil Drug Interactions
Drug Name
Risk Level
Description
Acenocoumarol
Major
The metabolism of Acenocoumarol can be decreased when combined with Fenofibrate.
Aluminium clofibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Aluminium clofibrate.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Fenofibrate.
Bezafibrate
Major
The risk or severity of adverse effects can be increased when Fenofibrate is combined with Bezafibrate.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Fenofibrate.
Lipidil Toxicity & Overdose RiskThe lowest toxic dose of fenofibrate in rats is greater than 2g/kg and 1600mg/kg in mice. If someone has recently overdosed on fenofibrate, they should be monitored and treated with supportive care, such as inducing vomiting or gastric lavage. Since it binds to proteins, hemodialysis is not likely to be effective.
image of a doctor in a lab doing drug, clinical research

Lipidil Novel Uses: Which Conditions Have a Clinical Trial Featuring Lipidil?

Fifteen active trials are investigating the use of Lipidil to treat severe Fredrickson Type V Hypertriglyceridemia, Hypertriglyceridemia and Dyslipidemias.
Condition
Clinical Trials
Trial Phases
Hypertriglyceridemia
4 Actively Recruiting
Phase 3
severe Fredrickson Type V Hypertriglyceridemia
0 Actively Recruiting
Dyslipidemias
1 Actively Recruiting
Phase 2
Hypertriglyceridemia
0 Actively Recruiting
Primary Hypercholesterolemia
15 Actively Recruiting
Early Phase 1, Not Applicable, Phase 3, Phase 2

Lipidil Reviews: What are patients saying about Lipidil?

5Patient Review
9/20/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I was initially prescribed statins, which caused memory problems and extreme muscle weakness. These effects lingered for three years before my doctor switched me to Welchol. While this helped somewhat, it wasn't enough so he added 145mg of finofibrate to the mix. This lowered my cholesterol significantly with no noticeable side effects.
5Patient Review
9/14/2014
Lipidil for High Cholesterol
I've been doing great since having my gallbladder removed. This treatment was definitely worth it.
5Patient Review
1/5/2019
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I experienced none of the negative side effects that others have described. This drug was also much more effective than any other treatment I've tried in the past. I go for blood work every 3 months and haven't seen any signs of this drug affecting my body negatively.
5Patient Review
6/3/2017
Lipidil for High Amount of Triglyceride in the Blood
In addition to a statin drug, this treatment halved my triglyceride levels.
5Patient Review
9/14/2014
Lipidil for High Cholesterol
I had to get my gallbladder removed, but I've been doing great since then.
5Patient Review
9/20/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I was originally prescribed statins, which caused problems with muscle weakness and memory. After three years, my doctor switched me to Welchol, which helped somewhat but didn't lower my cholesterol enough. He then added 145 mg of finofibrate, and my numbers decreased significantly with no noticeable side effects.
5Patient Review
1/5/2019
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I had a great experience with this drug and saw significant improvements compared to other treatments I've tried in the past. I didn't experience any of the negative side effects that others have described, and my blood work has been normal since starting this medication.
5Patient Review
3/12/2019
Lipidil for High Amount of Triglyceride in the Blood
I've been taking this medication for a few years to help manage my cholesterol levels. It's worked great with no negative side effects that I've experienced.
5Patient Review
6/3/2017
Lipidil for High Amount of Triglyceride in the Blood
In addition to taking a statin medication, this drug helped me to lower my triglyceride levels by half.
5Patient Review
3/12/2019
Lipidil for High Amount of Triglyceride in the Blood
I've been taking this medication for a few years to help manage my cholesterol levels. It's worked great for me with no noticeable side effects.
4.3Patient Review
1/31/2017
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I've tried every statin on the market, and each one led to a deterioration of my health in some way: muscle loss, memory issues, vertigo, etc. I finally gave up on them and switched to Fenofibrate. Later, I combined it with Zetia, and my numbers came down to the same range as when I was taking statins--but without any of the negative side effects!
4.3Patient Review
1/31/2017
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I've tried every statin on the market, and each one caused me debilitating side effects like muscle deterioration, memory loss, and vertigo. I stopped taking them altogether and saw a significant improvement in my overall health. I started Fenofibrate, which combined with Zetia brought my numbers down to the same range as when I was taking statins. Plus, no negative side effects!
4Patient Review
11/28/2017
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
This treatment has done great things for my blood fats, but I have noticed that food doesn't taste as good as it used to.
4Patient Review
11/28/2017
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
This treatment has effectively lowered my blood fats, but I have noticed that food doesn't taste as good anymore.
3.7Patient Review
11/20/2021
Lipidil for High Amount of Triglyceride in the Blood
I'm on fenofibrate 145mg daily. I stopped taking statins because they made me feel incredibly tired, and this 3-week trial of fenofibrate has brought my triglycerides down but the fatigue has started to come back. I'll have to go off of it and find something else that works better.
3.7Patient Review
11/20/2021
Lipidil for High Amount of Triglyceride in the Blood
I was taking 145mg of fenofibrate daily, but I stopped because I started to feel very tired again. This drug had lowered my triglycerides dramatically, but the tiredness was not worth it.
3Patient Review
10/18/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I had to stop taking fenofibrate because it caused muscle pain and weakness. My cholesterol was unreadable because it's so high. The drug did more harm than good, but I feel better now that I'm off of it.
3Patient Review
4/26/2021
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I haven't had my blood work done since starting fenofibrate 54mg 8 weeks ago, but I can tell you that it really helped me lower my triglic levels. I would highly recommend this medication to others.
3Patient Review
10/18/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I had to stop taking fenofibrate due to muscle pain and weakness. My cholesterol was unreadable it's so high. The drug did more harm than good. Now that I'm off it, I feel better. Still on Zetia and Pravastatin. Thinking of discontinuing those also.
3Patient Review
4/26/2021
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I had to get my blood work done after starting fenofibrate 54mg generic 8 weeks ago. My triglic levels were451! I'm following a strict diet and I hope to see a huge improvement, but I'm quitting this med. The amount of laxatives is ridiculous, amoung the other nonsense stated by others here. Diabetes + stress + pie = bad! Avoid drugs, take a lesson.
2.3Patient Review
8/4/2022
Lipidil for High Amount of Triglyceride in the Blood
I tried this for three weeks and had to stop. I felt tired, constipated, weak, light-headed, and couldn't sleep. I don't know if it did anything for my triglycerides because I was supposed to take it for 90 days. Maybe age is a factor?
2.3Patient Review
5/18/2016
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
This medication didn't help me sleep; in fact, it made my insomnia worse. As someone who already struggles with fibromyalgia and chronic pain, this was the last thing I needed.
2.3Patient Review
4/28/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
Unfortunately, this medication didn't help with my cholesterol at all. On top of that, it's given me headaches and constipation while also causing weight gain.
2.3Patient Review
5/18/2016
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
Unfortunately, this medication didn't help me sleep; if anything, it made my restless nights worse. As a result, I'm taking more pain medication to cope with the increased body pain that comes from less sleep.
2.3Patient Review
8/4/2022
Lipidil for High Amount of Triglyceride in the Blood
I'm 72, and after just three weeks on this medication, I already feel significantly worse. I'm more tired than usual, constipated, weak, lightheaded, and having trouble sleeping. Fenofibrate is supposed to be taken for 90 days to see if it's effective in lowering triglyceride levels; however, based on how I feel currently, I don't think I'll make it that long.
2.3Patient Review
4/28/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
This medication gives me headaches, constipation, and weigh gain. Plus, it didn't do anything to help my cholesterol levels. If a medication isn't going to provide any benefits, there's no point in taking it!
2Patient Review
9/12/2022
Lipidil for High Cholesterol
After my doctor switched me to this medication, Feno, I only took it three times before deciding to stop. It made me feel lightheaded and uncoordinated, which isn't worth the risk of having higher cholesterol levels.
2Patient Review
9/12/2022
Lipidil for High Cholesterol
I was switched to Feno by my doctor because statins were giving me joint pain. Unfortunately, after only three doses I had to stop taking it. It made me feel lightheaded and unsteady, which is not worth the risk of having higher cholesterol levels.
1.7Patient Review
8/17/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
Unfortunately, the Fenofribate and Atorvastatin caused me a lot of pain in my arms and neck, as well as muscle weakness. I tried stopping and starting the medication a few times to see if the pain was related to the meds, and it definitely was. Thankfully, once I stopped taking them completely, the pain went away.
1.7Patient Review
1/21/2018
Lipidil for High Amount of Fats in the Blood
I had to stop taking this after only twelve days because the side effects were so bad. I felt incredibly tired, got headaches, and my pain was amplified. No thanks; I'll take my chances without it.
1.7Patient Review
8/17/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I found that taking Fenofribate and Atorvastatin caused me pain in my arms and neck, as well as muscle weakness. I tried stopping and starting the medication a few times to see if it was just coincidence, but every time I took the medication I experienced these problems. Thankfully, once I stopped taking the medication altogether my symptoms went away.
1.7Patient Review
8/26/2016
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
The side effects of this drug (muscle pain, weakness, memory problems and weight gain) are not worth the very slim chance it could heart disease. I'm 78 years old and have no signs of heart disease, so I don't need this medication. My doctor wasn't happy with my decision, but I am.
1.7Patient Review
1/21/2018
Lipidil for High Amount of Fats in the Blood
I personally had to stop taking this after only 12 days due to the incredibly negative side effects. I felt very tired, my headache and pain got worse, and I just generally had zero energy. To me, it's not worth it.
1.7Patient Review
8/26/2016
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
The side effects of this medication (muscle pain, weakness, memory problems, weight gain) are not worth the very small chance it might help prevent heart disease. I'm 78 years old and have no signs of heart disease, so there's no need for me to take this drug.
1Patient Review
5/15/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I started taking three medications at the same time, and soon after I developed a rash over my arms, legs, and back. After doing some research, I realized that the culprit was one of the medications. Needless to say, I stopped taking it immediately.
1Patient Review
2/9/2020
Lipidil for High Cholesterol
I was very disappointed when they raised the price of this drug. I now have to pay a deductible, which is not affordable for me.
1Patient Review
5/15/2015
Lipidil for Combined High Blood Cholesterol and Triglyceride Level
I started taking three different medications and then developed a rash that covered my arms, legs, and back. After doing some research, I discovered that the culprit was one of the medications. Needless to say, I stopped taking it and hopefully the rash will clear up soon.
1Patient Review
3/15/2020
Lipidil for High Amount of Triglyceride in the Blood
DO NOT TAKE THIS PILL. I threw up violently and had excruciating stomach and back pain after just three doses. It was like ingesting rat poison.
1Patient Review
2/9/2020
Lipidil for High Cholesterol
I was very disappointed when they raised the price of this drug. Now I have to pay a 380.00 dollar deductible, which is just not feasible for me.
1Patient Review
3/15/2020
Lipidil for High Amount of Triglyceride in the Blood
Just say no to this pill. It caused me so much pain and vomiting that I felt like I had ingested rat poison.

Patient Q&A Section about lipidil

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Lipidil have side effects?

"If you experience any of the following side effects, see your doctor as soon as possible:

Signs of liver problems, such as dark urine, general feeling of being unwell, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin."

Answered by AI

What is the generic name for Lipidil?

"The generic name for fenofibrate is fenofibrate. It is a medication that is used to treat high cholesterol and triglyceride levels in the blood. It is a Prescription Only Medicine (POM) which means it can only be prescribed by a healthcare professional."

Answered by AI

When should Lipidil be taken?

"The recommended dosage of Lipidil 145 mg and 48 mg is to be taken at the same time each day, with or without food."

Answered by AI

What is Lipidil for?

"LIPIDIL is used to help regulate cholesterol and triglycerides in the blood. These are fat-like substances that can build up and cause problems."

Answered by AI

Clinical Trials for Lipidil

Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.
Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.
Have you considered Lipidil clinical trials? We made a collection of clinical trials featuring Lipidil, we think they might fit your search criteria.